DIRAS1 Drives Oxaliplatin Resistance in Colorectal Cancer via PHB1-Mediated Mitochondrial Homeostasis by Min Long, Qian Ouyang, Jingyi Wen, Xuan Zeng, Zihui Xu, Shangwei Zhong, Changhao Huang, Jun-Li Luo

“…The role of DIRAS1, a RAS superfamily member with reported tumor-suppressive functions in various cancers, remains poorly defined in CRC. Methods: The effects of DIRAS1 on CRC cell proliferation and migration were evaluated using MTT, wound healing, and colony formation assays. …”
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An anthropomorphic phantom for atrial transseptal puncture simulation training by Aya Mutaz Zeidan, Zhouyang Xu, Lisa Leung, Calum Byrne, Sachin Sabu, Yijia Zhou, Christopher Aldo Rinaldi, John Whitaker, Steven E. Williams, Jonathan Behar, Aruna Arujuna, R. James Housden, Kawal Rhode

“…This study presents a novel, patient-specific, anthropomorphic phantom for TSP simulation training that can be used with X-ray fluoroscopy and ultrasound imaging. Methods The TSP phantom was developed using additive manufacturing techniques and features a replaceable fossa ovalis (FO) component to allow for multiple punctures without replacing the entire model. …”
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Older patients affected by COVID-19: investigating the existence of biological phenotypes by Alberto Zucchelli, Marta Parigi, Silvia Giliani, Davide Liborio Vetrano, Daniela Lucente, Emanuele Marzetti, Riccardo Calvani, Giuseppe Bellelli, Alessandra Marengoni

“…Frailty was identified in 42% of the sample and 27.2% were unable to ambulate outdoors. …”
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Ten recommendations for scanning foraminifera by X-ray computed tomography by A. Searle-Barnes, A. Brombacher, A. Brombacher, O. Katsamenis, O. Katsamenis, K. Rankin, M. Mavrogordato, T. Ezard

“…</p> <p>The values of these parameters can exhibit significant variability across individuals, based on the specific needs of the study, the equipment used, and the unique attributes of the samples under consideration. Our motivation with this paper is to share our experience and offer a foundation for similar studies.…”
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Development of an artificial intelligence-based multimodal diagnostic system for early detection of biliary atresia by Ya Ma, Yuancheng Yang, Yuxin Du, Luyang Jin, Baoyu Liang, Yuqi Zhang, Yedi Wang, Luyu Liu, Zijian Zhang, Zelong Jin, Zhimin Qiu, Mao Ye, Zhengrong Wang, Chao Tong

“…This study aims to leverage diverse data sources and formats to develop an intelligent diagnostic system for BA. Methods We constructed the largest known multimodal BA dataset, comprising ultrasound images, clinical data, and laboratory results. …”
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Evaluation of Medical School Students in Terms of Attention Deficit Hyperactivity Disorder and Emotional Regulation Difficulties by Ayşe Akan, Engin Burak Selçuk, Burcu Kayhan Tetik, Mustafa Akan, Ahmet Kadir Arslan

“…This study aimed to evaluate ADHD symptoms and emotional regulation difficulties in medical students studying at a university hospital. Methods: The research was conducted between 20.10.2021 and 20.11.2021 in the family medicine department of a university hospital. …”
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Quality of life in older patients with cancer and related unmet needs: a scoping review by Franziska Springer, Ayumu Matsuoka, Kyoko Obama, Anja Mehnert-Theuerkauf, Yosuke Uchitomi, Maiko Fujimori

“…This scoping review aims to synthesize findings on quality of life (QoL) in older adults with cancer, comparing them to younger counterparts and older individuals without cancer, and identifying associated factors. Methods: PubMed and PsychINFO databases were searched for articles published until January 2024. …”
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The challenging reality of the clinical learning environment at Damascus University Faculty of Dental Medicine in Syria: A qualitative study [version 4; peer review: 1 approved, 3... by Khattab Mustafa, Issam Jamous, Bashar Jazayerli, Ghaith Alfakhry, Khaled Alhomsi

“…This study aimed to obtain in-depth qualitative understanding of the clinical learning environment at Damascus University Faculty of Dental Medicine, Syria. Methods Semi-structured interviews were held with eight postgraduate dental students at Damascus University Faculty of Dental Medicine. …”
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Changes in grocery shopping behaviour among low-income households during the COVID-19 pandemic by Angela CB Trude, Caitlin M Lowery, Gabriela M Vedovato, Shahmir H Ali, Josephine M Dudzik

“…Design: In this mixed-methods study, participants completed a survey on online grocery shopping, and a purposefully sampled subset participated in focus groups or in-depth interviews between November 2020 and March 2021. …”
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Optimising fatigue, abdominal pain and faecal incontinence in people with inflammatory bowel disease (IBD-BOOST Optimise): feasibility study of a checklist and algorithm for initia... by Thomas Hamborg, John McLaughlin, Ailsa Hart, Christine Norton, Sonia Bouri, Laura Miller, Jean-Frédéric LeBlanc, Asma Fikree, Imogen Stagg, Fionn Cléirigh Büttner

“…Objective Many people with inflammatory bowel disease (IBD) experience fatigue, pain and faecal incontinence that some feel are inadequately addressed. …”
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The use of peer support groups for emergency physicians during the COVID‐19 pandemic by Jill Nault Connors, Tanner Thornsberry, Julie Hayden, Kurt Kroenke, Patrick O. Monahan, Claire Draucker, Sally Wasmuth, Heather Kelker, Anne Whitehead, Julie Welch

“…Abstract Objective To test the feasibility, receptivity, and preliminary effectiveness of peer support groups for emergency medicine physicians during the COVID‐19 pandemic and gain a better understanding of their experiences with peer support. Methods This pilot study used a quasi‐experimental design to assess change in symptoms of distress, anxiety, depression and burn‐out before and after participating in a virtual, group‐based peer support intervention for a duration of 8 weeks. …”
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Prevalence of comorbidities and sur alence of comorbidities and survival analysis of CO al analysis of COVID-19 patients – an obser patients – an observational study fr ational stu... by Mihaela-Simona Popoviciu, Lorena Păduraru, Roxana Adriana Stoica, Anca Pantea Stoian, Claudiu Teodorescu, Simona Cavalu

“…In this context, the aim of our study was to perform a retrospective, observational study in order to assess the time-to-death and risk factors of mortality among COVID-19 patients. Materials and Methods. The study was conducted on 177 patients admitted to Oradea Emergency County Hospital, Bihor, Romania, between October and December 2021. …”
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Research on the differences of RF port simulation and test of X-band power device package by Yan Huizeng, Shi Mengqiao, Zhou Hao, Chen Huanbei

“…This paper discussed research on the differences of RF Port simulation and test of X-band power device package which was based on probe test method. After optimizing it with simulation software, samples are produced through HTCC process line, the result of testing the port with GSG probe is much larger than the simulation results. …”
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Effect of an Extended Reality Simulation Intervention on Midwifery Students’ Anxiety: Systematic Review by Clara Pérez de los Cobos Cintas, Nicolas Vuillerme, Guillaume Thomann, Lionel Di Marco

“… Abstract BackgroundMidwifery students often experience anxiety due to several factors, such as the clinical experiences faced. …”
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Factors Related to Evidence-Based Practices Among Mental Health Nurses in Thailand: A Cross-Sectional Study by Napapat Manitkul, Kwaunpanomporn Thummathai, Patraporn Bhatarasakoon

“…This correlational descriptive research aimed to explore the factors and examine the relationship between attitudes, knowledge/skills, organizational culture, mentorship, and demographic factors to evidence-based practices among mental health nurses working in psychiatric hospitals in Thailand. Methods: The sample consisted of 255 nurses working in psychiatric hospitals under the Thai Department of Mental Health, located in service units across the country’s four regions. …”
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Refractive Corneal Lenticule Extraction by CLEAR: Analysis of our own Data 700 Patients by К. B. Pershin, Yu. S. Kudryavtseva, N. F. Pashinova, А. Iu. Tsygankov, E. A. Antonov

“…Purpose: analysis of the results of using CLEAR technique on a significant sample of patients with myopia of various degrees.Patients and methods. …”
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Exploring midwifery role and scope in acute early pregnancy care: a survey of midwives and midwifery students in Australia by Nicole Freeman, Tracey Moroney, Jane Warland, Kate Cheney, Michelle Hobday, Zoe Bradfield

“…A gap in evidence exists in relation to the role and scope of practice of the midwife in acute early pregnancy care provision in Australia. Methods Midwives and midwifery students in Australia were purposively sampled and invited to complete an online cross-sectional survey exploring midwifery practice in acute early pregnancy care. …”
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Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism by Lauren Wagner, Megan Banchik, Tawny Tsang, Nana J. Okada, Rebecca Altshuler, Nicole McDonald, Susan Y. Bookheimer, Shafali S. Jeste, Shulamite Green, Mirella Dapretto

“…Amongst infant siblings of children with an ASD diagnosis – who are at higher likelihood for developing ASD – a high proportion also show difficulties and delays in language acquisition. Methods In this study, we used functional magnetic resonance imaging (fMRI) to examine differences in language processing in 9-month-old infants at high (HL) and typical (TL) familial likelihood for ASD. …”
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Large language models underperform in European general surgery board examinations: a comparative study with experts and surgical residents by Melih Can Gül

“…This study compared the performance of four AI models (Llama-3, Gemini, GPT-4o, and Copilot) with specialists and residents on European General Surgery Board test questions, focusing on accuracy across question formats, lengths, and difficulty levels. Methods A total of 120 multiple-choice questions were systematically sampled from the General Surgery Examination and Board Review question bank using a structured randomization protocol. …”
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Exploration of the Gaps in the Enactment and Implementation of the Domestic Violence Act of South Africa by Sabelinah M. Tshoane, Paul O. Bello, Jacob T. Mofokeng, Adewale A. Olutola

“…A sample size of roughly 200 represents quantitative aspects. …”
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