Prospective Neuropsychological and Plasma Biomarker Changes in Treatment-Naïve People Living with HIV After Antiretroviral Treatment Initiation by Charalampos D. Moschopoulos, Evangelia Stanitsa, Konstantinos Protopapas, Akrivi Vatsi, Irene Galani, Henrik Zetterberg, Ion Beratis, Paraskevi C. Fragkou, Sotirios Tsiodras, Dimitra Kavatha, Antonios Papadopoulos, Sokratis G. Papageorgiou, Anastasia Antoniadou

“…Over 18 months, neurocognitive function improved, particularly in speed of information processing, executive function, and visuospatial ability, while verbal fluency, fine motor dexterity, and attention/working memory remained unchanged. …”
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A Comparative Analysis of Genetic and Epigenetic Factors in METH Addiction: A Focus on SLC (SLC6A4) and COMT Genes by Haider K. Hussain, Yolanda Loarce Tejada, Anna Barbaro

“…., 5-HTTLPR) were associated with an increased risk of METH addiction (odds ratio (OR) = 2.31, 95% confidence interval (CI): 1.45–3.68; p = 0.001); meanwhile, variations in COMT (Val158Met) were linked to both susceptibility and executive function deficits. Epigenetic modifications—most notably DNA methylation in SLC6A4 and COMT—also emerged as important contributors to addiction pathways, potentially influencing dopamine and serotonin regulation. …”
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Dysregulated C1q and CD47 in the aging monkey brain: association with myelin damage, microglia reactivity, and cognitive decline by Sarah A. DeVries, Christina Dimovasili, Maria Medalla, Maria Medalla, Tara L. Moore, Tara L. Moore, Douglas L. Rosene, Douglas L. Rosene

“…Normal aging, though lacking widespread neurodegeneration, is nevertheless characterized by cognitive impairment in learning, memory, and executive function. The aged brain is spared from neuron loss, but white matter is lost and damage to myelin sheaths accumulates. …”
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iKids study protocol: a longitudinal study to understand the impact of interactive electronic devices on the development and health of young children in England by Jenny Retzler, Daniel Jones, John J Reilly, John Stephenson, Stuart Fairclough, Christine Smith, Amy Hughes, Tony Okely, Liane Beretta De Azevedo, João Paulo de Aguiar Greca, Colette Marr

“…However, concerns exist regarding their potential negative impacts on children’s self-regulation, parent-child interaction and physical activity.The primary aim of this study is to understand the longitudinal impact of IED use, in particular duration (hours per day) and mode (educational vs non-educational; age-appropriate vs non-age-appropriate), on emerging abilities (ie, self-regulation, social development, executive function, language and numeracy) in 3-year-old to 5-year-old children. …”
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Developmental changes in independent bimanual coordination: evidence from the circles–lines coupling task in children aged 5–13 years by Satoshi Nobusako, Satoshi Nobusako, Kenya Hashizoe, Kenya Hashizoe, Akio Nakai

“…Partial correlation analyses, controlling for age, revealed significant associations between BCE/BM-OI and bimanual motor skills, suggesting that the ability to overcome intermanual interference is closely linked to age-appropriate bimanual coordination.DiscussionGiven that asymmetric bimanual control involves not only the fronto-parietal network but also executive functions in the prefrontal cortex and interhemispheric motor communication, the present behavioral findings may reflect multifaceted neural maturation during childhood—specifically, the development of the fronto-parietal network, prefrontal cortex, and transcallosal motor pathways. …”
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Mediating role of Interleukin-6 in the predictive association of diabetes with Hippocampus atrophy, Amyloid, Tau, and Neurofilament pathology at pre-clinical stages of diabetes-rel... by Asma Hallab, Sid E. O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson, Meredith Braskie, Kevin King, James R. Hall, Melissa Petersen, Raymond Palmer, Robert Barber, Yonggang Shi, Fan Zhang, Rajesh Nandy, Roderick McColl, David Mason, Bradley Christian, Nicole Phillips, Stephanie Large, Joe Lee, Badri Vardarajan, Monica Rivera Mindt, Amrita Cheema, Lisa Barnes, Mark Mapstone, Annie Cohen, Amy Kind, Ozioma Okonkwo, Raul Vintimilla, Zhengyang Zhou, Michael Donohue, Rema Raman, Matthew Borzage, Michelle Mielke, Beau Ances, Ganesh Babulal, Jorge Llibre-Guerra, Carl Hill, Rocky Vig

“…Results: T2DM and IL-6 were associated with worse executive function, Hippocampus atrophy, lower Aß42/Aß40 ratio, and higher Aß40, Aß42, total Tau, and NfL levels. …”
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The impact of physical exercise interventions on social, behavioral, and motor skills in children with autism: a systematic review and meta-analysis of randomized controlled trials by YanAn Wang, Guoping Qian, Sujie Mao, Shikun Zhang

“…BackgroundAutism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social impairments, sensory processing issues, repetitive behavior patterns, motor abnormalities, and executive function impairments.ObjectiveTo systematically review and meta-analyze the effects of various exercise modalities on flexibility and cognitive control, social skills, behavioral problems, motor skills, and coordination in children with ASD, providing scientific evidence for clinical practice to guide effective exercise interventions for children with ASD.MethodsLiterature searches were conducted in PubMed, EMbase, Cochrane Library, EBSCOhost, and Web of Science databases, covering the period from database inception to February 15, 2024. …”
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Cognitive deficits in multiple sclerosis: a systematic review Déficits cognitivos na esclerose múltipla: uma revisão sistemática by Maria Lúcia Brito Ferreira

“…RESULTS: There is consensus on cognitive impairment of multiple sclerosis patients, especially on memory, speed processing, executive function, attention and concentration domains. …”
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Associations between sleep quality, plasma neurofilament light, and cognition in older adults without dementia by Hai-Hua Guo, Dong-Xin Liang, Qun Zhang, Yan Fu, Liang-Yu Huang, Ze-Hu Sheng, Lan Tan, Zuo-Teng Wang

“…Baseline and follow-up demographics, sleep indices, plasma NFL levels, and cognition scores (including Mini-Mental State Examination [MMSE], Montreal Cognitive Assessment [MoCA], Alzheimer’s Disease Assessment Scale-Cognitive Subscale [ADAS13], Clinical Dementia Rating Scale-Sum of Boxes [CDRSB], Executive Function [EF], Language [LAN], and Memory [MEM]) were also collected. …”
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Psychotic relapse prediction via biomarker monitoring: a systematic review by Alexandros Smyrnis, Christos Theleritis, Christos Theleritis, Panagiotis Ferentinos, Nikolaos Smyrnis, Nikolaos Smyrnis

“…After exclusion of studies related to the distinction of patients from controls or treatment effects, the 42 remaining studies were divided into 5 groups, based on the type of biomarker used as a predictor: the genetic biomarker subgroup (n = 4, or 9%), the blood-based biomarker subgroup (n = 15, or 36%), the neuroimaging biomarker subgroup (n = 10, or 24%), the cognitive-behavioral biomarker subgroup (n = 5, or 12%) and the wearables biomarker subgroup (n = 8, or 19%).ResultsIn the first 4 groups, several factors were found to correlate with the state of relapse, such as the genetic risk profile, Interleukin-6, Vitamin D or panels consisting of multiple markers (blood-based), ventricular volume, grey matter volume in the right hippocampus, various functional connectivity metrics (neuroimaging), working memory and executive function (cognition). …”
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Probabilitas Pelaksanaan Hak Angket Terhadap Pemilihan Umum di Indonesia by Nuranida Hasanah, Wicipto Setiadi

“… This study aims to analyze the role of the right of inquiry in the Parliament's oversight function juridically and the probability of using the right of inquiry in elections in Indonesia. …”
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Reduction in Brain Parenchymal Volume Correlates with Depression and Cognitive Decline in HIV-Positive Males by Radmila Perić, Duško Kozić, Snežana Brkić, Dajana Lendak, Jelena Ostojić, Vojislava Bugarski Ignjatović, Jasmina Boban

“…Additional correlations were found with the anterior and middle cingulate gyri, which are crucial for executive functioning and attentional control. Notably, smaller right basal forebrain volumes were associated with greater depressive symptom severity, suggesting the region’s specific involvement in mood regulation. …”
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Dynamin-1 is a potential mediator in cancer-related cognitive impairment by Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M. Acharya, Alexandre Chan

“…Dynamin-1 (DNM1) is crucial for synaptic activity, neurotransmission, and associative memory, positioning it as a potential biomarker of cancer-related cognitive impairment (CRCI), a neurological consequence of cancer treatment characterized by memory loss, poor concentration, and impaired executive function. Through a stepwise approach, this study investigated the role of DNM1 in CRCI pathogenesis, incorporating both human data and animal models. …”
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Sequential consumption of sauce- and elegant-flavor baijiu enhances post-drinking comfort: a randomized crossover study in Guangdong, China by Yu Fu, Jianan Liu, Guoliang He, Shaohui Fan, Deliang Wang, Cheng Wang

“…Positive affect was greater at both time points (p < 0.01), with no change in negative affect.Sequential consumption of sauce-flavor followed by elegant-flavor baijiu appears to accelerate alcohol elimination, enhance executive function, and promote positive emotional recovery. …”
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Social and Emotional Learning: Easing the Transition to High School for 2e Learners by Charles Willis, C. Matthew Fugate

“…This transition can be particularly difficult for twice-exceptional students who often struggle with the necessary executive functioning skills needed to meet these expectations, as well as their own self-awareness, self-efficacy, and the self-advocacy skills they need to help ease this transition. …”
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The Presidentialization of Political Parties Due to Presidentialized Systems of Government: Theoretical  nsights with Reference to the Fifth French Republic by Łukasz Jakubiak

“…This also affects the functioning of political parties. Hence, the aim of the article is to identify the key characteristics of presidentialized political parties that operate within presidentialized systems of government. …”
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The instrument of interpellation in parliamentary law in France by Vučković Jelena P., Kovačević Anika N.

“…The authors define and thoroughly analyze the characteristics, functions and significance of interpellation, which represents the traditional parliamentary prerogative in the area of political control of the executive authority, while it also represents a significant right of members of parliament, which is both individual and collective. …”
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Formation of the runoff of small rivers in a large city of the Volga basin (on the example of Nizhny Novgorod). by Sergey V. Yasinsky, Maria B. Alieva, Marina V. Shmakova

“…Small rivers perform two functions: they are part of the ecological framework and as fl ow systems, they remove large volumes of pollutants. …”

Midlife cognitive testing in Africa: validity of the Harmonised Cognitive Assessment Protocol in the Kenya Life Panel Survey by Jinkook Lee, Anthony Ngugi, Joshua R Ehrlich, William H Dow, Alden L Gross, Madeline Duhon, Eric Ochieng, Jean N Ikanga, Michael W Walker, Michelle Layvant, Edward A Miguel

“…The HCAP assessment was administered in 2023 at an average age of 37 years (10–90 range 34 to 41).Primary and secondary outcome measures For each individual, the CFA generates a general cognitive performance score, and cognitive performance scores for five distinct domains, including memory, executive functioning, language, orientation to time and place, and visuospatial functioning.Results Fit of the models to the data was adequate for general cognitive performance (root mean squared error of approximation (RMSEA)=0.03; comparative fit index (CFI)=0.94; standardised root mean residual (SRMR)=0.05), language (RMSEA=0.02; CFI=0.95; SRMR=0.05) and good for memory (RMSEA=0.05; CFI=0.99; SRMR=0.02) and executive functioning (RMSEA=0.03; CFI=0.98; SRMR=0.03). …”
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Diagnosis and treatment of vascular cognitive disorders by V. V. Zakharov

“…CI in subcortical variant is characterized with attention and executive functions deficit, frequently in combination with emotional disorders, postural instability and gait disturbances of frontal origin. …”
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