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281
Navigating the Uncommon: Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Successfully Managed with Implantable Cardioverter Defibrillator (ICD)
Published 2024-10-01“… With a high risk of sudden cardiac mortality, arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited cardiomyopathy characterized by right ventricular dysfunction and ventricular arrhythmias (VA). In this case study, a 35-year-old presented with palpitations and revealed epsilon waves on the right precordial electrocardiogram (ECG) leads which led to the suspicion of ARVC. …”
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282
Resting-State Functional MRI in Dyslexia: A Systematic Review
Published 2025-05-01“…Increased and decreased connectivity in various regions related to executive function, language, and salience processing indicate that broader cognitive mechanisms play a key role in reading performance.…”
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283
Study on Large‐Scale Brain Network Abnormalities in Patients With Beta‐Thalassemia
Published 2025-06-01“…Results In β‐TM patients, FC within brain networks was significantly reduced in the anterior default mode network (aDMN), posterior default mode network (pDMN), left frontoparietal network (lFPN), right frontoparietal network (rFPN), ventral attention network (VAN), and executive control network (ECN). In contrast, FC was significantly increased in the dorsal sensorimotor network (dSMN) and posterior visual network (pVN). …”
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284
Obesity-related alterations of intrinsic functional architecture: a resting-state fMRI study based on the human connectome project
Published 2025-05-01“…Additionally, the fALFF alterations in insula/temploral pole and also the rDLPFC-PCL FC partially mediated the relationship between body mass index and the executive function. Furthermore, cross-modal correlation analyses indicated that ICC and fALFF alterations were related to noradrenaline transporter and dopamine receptor distributions, respectively.DiscussionTogether our findings suggested that obesity is associated with atypical neurotransmitter systems and dysfunctional architecture especially in the prefrontal cortex, insula, sensorimotor cortex, and default mode circuits. …”
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285
Recent Advances in the Molecular Mechanisms Underlying Pyroptosis in Sepsis
Published 2018-01-01“…Sepsis is recognized as a life-threatening organ dysfunctional disease that is caused by dysregulated host responses to infection. …”
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286
Protocol for assessing auditory function, cochlear synaptopathy, and afferent terminal morphology in laboratory mice
Published 2025-09-01“…This protocol provides a reproducible framework for studying molecular-structural synaptopathy in mouse models of cochlear dysfunction.For complete details on the use and execution of this protocol, please refer to Pal et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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287
Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms
Published 2012-01-01“…., cancer, cardiopathies, nonalcoholic fatty liver diseases, and neurodegenerative diseases), mitochondria can receive harmful signals, dysfunction and then, participate to pathogenesis. They can undergo either a decrease of their bioenergetic function or a process called mitochondrial permeability transition (MPT) that can coordinate cell death execution. …”
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288
Impaired flexibility in patients with tropical spastic paraparesis/HTLV-associated myelopathy: evaluation via pendulum fleximeter
Published 2023-03-01“… Background Flexibility is crucial to the harmonious execution of joint movements. While skeletal muscle dysfunction in patients with HTLV-1 can interfere with mobility, it is unclear whether these patients experience reduced flexibility.…”
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289
Perioperative Management of Type-3c Gaucher's Disease for Kyphoscoliosis Correction and Spinal Cord Detethering
“…Thorough preoperative evaluation, meticulous planning, and execution with adequate backup plans and appropriate pain management helped with faster recovery.…”
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290
Inhibition of VDAC1 oligomerization blocks cysteine deprivation-induced ferroptosis via mitochondrial ROS suppression
Published 2024-11-01“…Our results demonstrate that the mitochondria-targeted antioxidants MitoQ and MitoT effectively block ferroptosis induction and that dysfunction of complex III of the mitochondrial electron transport chain contributes to ferroptosis induction. …”
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291
Resveratrol combats chronic diseases through enhancing mitochondrial quality
Published 2024-03-01“…Resveratrol (RSV), as a functional food component extracted from natural plants, has been widely studied and recognized in preventing and treating various diseases, with major mechanisms including executing anti-inflammation and anti-oxidation functions, and improving mitochondrial quality. …”
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292
The amygdala and the pursuit of future rewards
Published 2025-01-01“…Based on this framework, we suggest that amygdala neurons constitute vulnerabilities for dysfunction that contribute to maladaptive reward pursuit in psychiatric and behavioral conditions. …”
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293
Мodification of Mechanical Limbal Stem Cell Deficiency Model
Published 2018-03-01“…Ocular surface diseases related with limbal epithelial stem cells dysfunction were united in term “limbal stem cell deficiency” (LSCD). …”
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294
Cortico-striatal action control inherent of opponent cognitive-motivational styles
Published 2025-02-01“…Furthermore, we investigated rats exhibiting preferably goal-directed (goal trackers, GTs) versus cue-driven attention (sign-trackers, STs), to determine the impact of such cognitive-motivational biases on cortico-striatal control. GTs executed more cued turns and initiated such turns more slowly than STs. …”
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295
A Pneumatic Soft Glove System Based on Bidirectional Bending Functionality for Rehabilitation
Published 2025-02-01“…Stroke-related hand dysfunction significantly limits the ability to perform daily activities. …”
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296
Effectiveness, Tolerability and Safety of a Compound Based on D-chiro-inositol + Myo-inositol, Melatonin, Folic Acid, and Vitamin D in Patients with Menstrual Cycle Disorders
Published 2024-02-01“…These disorders often encompass ovulatory dysfunction, accompanied by analytical and clinical anomalies linked to hyperandrogenism, collectively defining polycystic ovary syndrome (PCOS). …”
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297
Platelets and diseases: signal transduction and advances in targeted therapy
Published 2025-05-01“…Originating from megakaryocytes in the bone marrow, platelets are small in size but possess a highly specialized structure that enables them to execute a wide range of physiological functions. The platelet cytoplasm is enriched with functional proteins, organelles, and granules that facilitate their activation and participation in tissue repair processes. …”
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298
A Bioimpedance-Based Device to Assess the Volume Conduction Properties of the Tongue in Neurological Disorders Affecting Bulbar function
Published 2021-01-01“…<italic>Goal:</italic> Current instruments for bulbar assessment exhibit technical limitations that hinder the execution of clinical studies. The volume conduction properties (VCP) of the tongue reflect ionic content and myofiber integrity and they can serve as a new biomarker for evaluating neurological disorders with bulbar dysfunction. …”
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299
Myocardial Hibernation in Patients with Arterial Hypertension and Ischemic Heart Disease as a Cause of Heart Failure
Published 2013-06-01“…Myocardial biopsies were obtained during the execution of the CABG for angina pectoris (n = 10) or ventriculoplasty in combination with CABG (n = 6). …”
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300
Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots
Published 2025-03-01“…Background: Partial heart transplantation (PHT) has emerged as a pioneering approach for treating infants with irreparable heart valve dysfunction. However, the scarcity of suitable donors presents a significant bottleneck to its widespread application. …”
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