Cognitive impairment and vulnerability of cholinergic brain network in the Alzheimer’s continuum: free-water imaging based on diffusion tensor imaging by Simin Zhao, Yuting Nie, Lulu Wen, Xinzuo Qin, Liyuan Huang, Changbiao Chu, Miao Qu, Miao Qu

“…In AD, the FWf within Ch4 was correlated with total MoCA score (R = −0.42, p = 0.015), especially with visual spatial/executive (R = −0.47, p = 0.006) and orientation deficits (R = −0.38, p = 0.029). …”
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Clinical, functional and neuropsychological status of joint replacement patients by Akhsarbek H. Dzhigkaev, Anastasia M. Tynterova, Ivan I. Kozenkov, Eldar V. Khaibulin, Elena V. Trofimova, Konstantin Y. Popadin, Konstantin V. Gunbin, Andrey G. Goncharov

“…Neuropsychological examination included assessment of cognitive and executive functions, levels of distress, depression, anxiety and somatization. …”

A domain-based framework for cognitive profile identification in Parkinson’s disease across diverse samples by Elvira Andújar-Castillo, Carla Carrillo-Molina, Fernando Alonso, Fernando Alonso, Clara Villanueva-Iza, Clara Villanueva-Iza, Gustavo Fernández-Pajarín, Gustavo Fernández-Pajarín, Angel Sesar, Angel Sesar, Isabel Jiménez-Martín, Isabel Jiménez-Martín, Juan Francisco Martín-Rodriguez, Juan Francisco Martín-Rodriguez, Juan Francisco Martín-Rodriguez, Maria Jesús Lama, Pablo Mir, Pablo Mir, Pablo Mir, Elena Perez-Hernandez, Cristina Nombela Otero

“…Traditional neuropsychological assessments often fall short in capturing the multifaceted nature of PD-related cognitive dysfunction due to their reliance on single test metrics. …”
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A Meta-Analysis of Task-Based fMRI Studies on Alcohol Use Disorder by Maxime Roberge, Mélanie Boisvert, Stéphane Potvin

“…<b>Conclusions:</b> These findings support prior research indicating a motivational imbalance and persistent executive dysfunctions in AUD. Standardizing consumption metrics and expanding task diversity in future research is essential to further refine our understanding of the neural effects of AUD.…”
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Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER): design and rationale for a decentralised, real-world cluster-randomised con... by Azeem Majeed, Rasha Al-Lamee, Ceire Costelloe, Daniel B Kramer, Carla M Plymen, Carys Barton, Emanuela Falaschetti, Nicholas S Peters, Josephine Mansell, Patrik Bachtiger, Mihir A Kelshiker, Camille F Petri, Abdullah Alrumayh, Saloni Nakhare, Melanie T Almonte, Alexei Peters

“…They will be supported to do so by a clinical guideline developed and approved by the regional health system executive board. Patient and outcome data will be captured from pooled primary and secondary care records, supplemented by qualitative and quantitative clinician surveys. …”
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Resting-State Network Plasticity Induced by Music Therapy after Traumatic Brain Injury by Noelia Martínez-Molina, Sini-Tuuli Siponkoski, Linda Kuusela, Sari Laitinen, Milla Holma, Mirja Ahlfors, Päivi Jordan-Kilkki, Katja Ala-Kauhaluoma, Susanna Melkas, Johanna Pekkola, Antoni Rodríguez-Fornells, Matti Laine, Aarne Ylinen, Pekka Rantanen, Sanna Koskinen, Benjamin Ultan Cowley, Teppo Särkämö

“…Traumatic brain injury (TBI) is characterized by a complex pattern of abnormalities in resting-state functional connectivity (rsFC) and network dysfunction, which can potentially be ameliorated by rehabilitation. …”
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Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Jiajun Fan, Yifei Han, Yu Lu, Han Jin, Yanming Wang, Hongjun Li, Peter Shaw

“…The analyses of LV-adjusted metrics also show that atrophic patterns observed in the hippocampus, thalamus and pallidum were strongly correlated with HAND(especially dysfunction in executive function) and clinical markers (i.e., CD4/CD8 ratio).ConclusionWe conclude that models that control for individual variability in intracranial and ventricular volumes have the potential to minimize discrepancies and variations in structural reports of HIV, improving the diagnostic power of identified patterns and fostering greater consistency across research studies. …”
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Microstate Co-Occurrence Matrices-Based Brain Activity Pattern Changes Analysis on Chronic Tinnitus Subjects by Yingying Wang, Gui Yang, Hongyu Liu, Xin Huang, Shuqing Han, Zhixiang Gu, Liyang Shao, Lei Zhang, Yuan Tao

“…The findings provide new insights into tinnitus-related brain network dysfunction and suggest EEG microstates co-occurrence probabilities as potential neurophysiological markers for diagnosis and intervention.…”
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Compensatory cerebellar activation during fluid intelligence processing following mild traumatic brain injury by Anat Leibovici, Nofar Itzhaki, Hadar Shapsa, Jenya Yvgeny, Lerer, Moran Shechtman, David Mesika, Reut Raizman, Galia Tsarfaty, Zion Zibly, Lior Ungar, Anton Peled, Raquel C. Gardner, Sigal Liraz Zaltsman, Moshe Bondi, Evgeny Gaidukov, Jeremy D. Schmahmann, Aleksandra Plavsic, Abigail Livny

“…Abstract Cognitive outcome following mild traumatic brain injury (mTBI) vary widely, with many individuals experiencing long-term impairments associated with frontoparietal network dysfunction. Mild TBI patients have demonstrated functional reorganization, suggesting an expansion of activation to cerebellar regions during specific executive functions. …”
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Differences in gait apraxia due to reduced regional cerebral blood flow in the supplementary motor area in corticobasal syndrome: a report of two cases by Kota Igari, Motoki Fujimaki, Mera Mai, Moe Sakuma, Shinji Saiki

“…For example, the freezing gait shown in Case 1 likely resulted from pre-SMA impairment, which is critical for movement initiation, while the exaggerated leg movements in Case 2 reflected dorsal SMA dysfunction, involved in motor execution. These results indicate that gait apraxia, which is often underdiagnosed, should be recognized as a potential early indicator of CBS. …”
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Cognitive and emotional disturbances in adult patients with myotonic dystrophy type 1 by E. K. Erokhina, K. V. Shamtieva, E. A. Melnik, D. O. Kazakov, S. A. Kurbatov, E. P. Pavlikova, O. A. Tikhonova, E. A. Mershina, V. E. Sinitsyn, D. V. Vlodavets

“…The group of patients with the congenital form had the most severe cognitive deficits, especially in tests of executive functions and visuospatial perception. Cognitive impairment was also characteristic of the adult form, but to a lesser extent. …”
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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…AD is associated with memory impairment, bvFTD with behavioral dysfunction, and MCI as a transitional stage between normal cognition and dementia. …”
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Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease by Arnau Puig‐Davi, Carla Franch‐Marti, Iñigo Ruiz‐Barrio, Frederic Sampedro, Jesus Perez‐Perez, Jordi A. Matias‐Guiu, Fernando Cuetos, Gonzalo Olmedo‐Saura, Laura Perez‐Carasol, Andrea Horta‐Barba, Ignacio Aracil‐Bolaños, Javier Pagonabarraga, Jaime Kulisevsky, Saul Martinez‐Horta

“…ABSTRACT Objective Huntington's disease (HD) speech/language disorders have typically been attributed to motor and executive impairment due to striatal dysfunction. In‐depth study of linguistic skills and the role of extrastriatal structures in HD is scarce. …”
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Comparing phthalate exposure between bottlenose dolphins (Tursiops truncatus) residing in urban and rural environments by Miranda K. Dziobak, Miranda K. Dziobak, Tita Curtin, Randall S. Wells, Ryan Takeshita, Cynthia R. Smith, Eric Zolman, Christina N. Toms, Christina N. Toms, Robyn F. Allen, Leslie B. Hart

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Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD by Yuanxin Zhong, Larry W. Baum, Justin D. Tubbs, Rui Ye, Lu Hua Chen, Tian Wu, Se-Fong Hung, Chun-Pan Tang, Ting-Pong Ho, Robert Moyzis, James Swanson, Chi-Chiu Lee, Pak C. Sham, Patrick W. L. Leung

“…Conclusions These findings re-validate the abnormal development of the neural system in ADHD and extend the existing neuro-dysfunction hypothesis to a multi-system perspective. …”
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Investigating the association of the plasma lipidomic profile with cognitive performance and genetic risk in the PsyCourse study by Mojtaba Oraki Kohshour, Sergi Papiol, Anna Tkachev, Elena Stekolshchikova, Kristina Adorjan, Monika Budde, Urs Heilbronner, Maria Heilbronner, Janos L. Kalman, Daniela Reich-Erkelenz, Sabrina K. Schaupp, Fanny Senner, Thomas Vogl, Jens Wiltfang, Eva Z. Reininghaus, Georg Juckel, Udo Dannlowski, Andreas J. Fallgatter, Carsten Spitzer, Max Schmauß, Martin von Hagen, Peter Falkai, Philipp Khaitovich, Thomas G. Schulze, Eva C. Schulte

“…Likewise, the association of polygenic risk scores (PRS) for SCZ, BD, executive function (EF), and educational attainment (EA) with lipid plasma levels were also investigated. …”
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Functional brain abnormalities in post COVID-19 condition and their relationship with cognition by Lourdes Carreras-Vidal, Laura Pacheco-Jaime, Mar Ariza, Neus Cano, Maite Garolera, Carla Garcia-Vicente, Ignacio Roura, Clara Capdevila-Lacasa, Javier Oltra, Jèssica Pardo, Cristina Martín-Barceló, Anna Campabadal, Roser Sala-Llonch, Nuria Bargallo, Cristian Barrué, Javier Bejar, Claudio Ulises Cortés, Carme Junqué, NAUTILUS-Project Collaborative Group, Bàrbara Segura

“…Among its symptoms is persistent cognitive dysfunction that is potentially linked to altered brain functional connectivity (FC). …”
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Induction of a Transient Dysexecutive Syndrome in Parkinson’s Disease using a Subclinical Dose of Scopolamine by M. A. Bédard, S. Lemay, J. F. Gagnon, H. Masson, F. Paquet

“…Parkinson’s Disease (PD) is often associated with a subcortico-frontal syndrome (SCFS) that is mainly characterized by executive dysfunctions. The complete biochemistry of these dysfunctions remain misunderstood although many studies have suggested a role of the dopaminergic lesions. …”
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Evaluating the effects of liraglutide, empagliflozin and linagliptin on mild cognitive impairment remission in patients with type 2 diabetes (LIGHT-MCI): study protocol for a multi... by Jie Liu, Jie Zhang, Wen Zhang, Ying Wang, Lu Zhang, Bing Zhang, Kun Wang, Weili Yan, Yan Bi, Zhou Zhang, Xiang Xu, Wenhui Zhu, Fangyi Li, Xiaoya Zhang, Xiaowei Zhu, Congcong Yu, Huijie Yang, Shihua Chen, Sijue Yang, Beibei Zhai, Tianyu Wu, Shengyi Zhao, Xuewei Tong, Yanjie Duan, Yining Chao, Jindan Wu, Xinhua Ye, Haiyan Cheng

“…Introduction Diabetes is a significant modifiable risk factor for cognitive dysfunction. There are currently no effective treatments that delay or reverse the progression of cognitive dysfunction. …”
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Application of Motor Imagery in Stroke Rehabilitation by WANG Jiayu, WANG Jiening, QI Rui

“…The applications of MI in stroke rehabilitation mainly cover upper limb motor dysfunction，lower limb motor dysfunction，swallowing and speech dysfunction，and depression following stroke. …”
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