Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies by Guangxu Zhang, Yuren Shi, Haoyu Ge, Yuanzhou Wang, Lu Lu, Shibo Jiang, Qian Wang

“…Here we conducted a comprehensive phylogenetic and comparative analysis of H5N1 clade 2.3.4.4b across multiple species, in order to identify the molecular characteristics and frequency of resistance mutations in these two genotypes, elucidate their evolutionary trajectories, and assess their implications for public health. …”
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Inverse design of adaptive flexible structures using physical-enhanced neural network by Moslem Mohammadi, Abbas Z. Kouzani, Mahdi Bodaghi, Ali Zolfagharian

“…The proposed metamaterial structure was experimentally validated through three-dimensional (3D) printing using flexible thermoplastic polyurethane (TPU) filament, demonstrating the efficiency and effectiveness of the proposed methodology.…”
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İletişim, İdeoloji ve Oyun Teorisi İlişkisi: Evrimsel Oyunlar, Ciddi Oyunlar ve Strateji Oyunları by Zeliha Oçak

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Arboreal camera trapping reveals diel-vertical migrations in arboreal wildlife of the Peruvian Amazon rainforest by Arata Honda, Chris Beirne, Ruthmery Pillco Huarcaya, Flor Perez Mullisaca, Caleb Quispe Quispe, Rosio Vega Quispe, Eleanor Flatt, Andrew Whitworth

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C→U transition biases in SARS-CoV-2: still rampant 4 years from the start of the COVID-19 pandemic by Peter Simmonds

“…However, only the most C→U polymorphic sites showed evidence for a preferred 5′U context previously associated with APOBEC 3A editing. There was a similarly weak preference for unpaired bases suggesting much less stringent targeting of RNA than mediated by A3 deaminases in DNA editing. …”
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Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection. by Maxwell Shapiro, Laurie T Krug, Thomas MacCarthy

“…We validated this model by analyzing the A3 evolutionary footprints in 25 HSV-1 isolates. …”
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Intranasally administered whole virion inactivated vaccine against clade 2.3.4.4b H5N1 influenza virus with optimized antigen and increased cross-protection by Jin-Ha Song, Seung-Eun Son, Ho-Won Kim, Seung-Ji Kim, Se-Hee An, Chung-Young Lee, Hyuk-Joon Kwon, Kang-Seuk Choi

“…By analyzing the evolutionary trends of clade 2.3.4.4b H5N1 viruses, we identified a key mutation (R90K) that increases heat stability while preserving antigenicity. …”
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Energy Consumption Analysis of Using Mashrabiya as a Retrofit Solution for a Residential Apartment in Al Ain Square, Al Ain, UAE by Lindita Bande, Anwar Ahmad, Saada Al Mansoori, Waleed Ahmed, Amna Shibeika, Shama Anbrine, Abdul Rauf

“…This study aims to investigate how an optimized mashrabiya pattern can impact the energy and the Predicted Mean Vote (PMV) in a 3-bedroom apartment, fully oriented to the south, of an expat family. …”
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Dualism of the Aging Process (analytical review) by V. N. Shabalin

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Brain-associated alterations of Hippo pathway transcription in early maturing Atlantic salmon by Ehsan Pashay Ahi, Jukka-Pekka Verta, Johanna Kurko, Annukka Ruokolainen, Pooja Singh, Paul Vincent Debes, Jaakko Erkinaro, Craig R. Primmer

“…A gene encoding a co-factor of the Hippo pathway, vgll3, is a major determinant of maturation timing in salmon. …”
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miR-122 shows potential as a biomarker and therapeutic target in NSCLC by inhibiting WNT/β-catenin and PI3K/AKT pathways and key transcription factors linked to EMT and metastasis by Amirbahador Abbasifarid, Ruhollah Dorostkar, Majdedin Ghalavand

“…Notable participants in these transformative changes include the PI3K/AKT and WNT/β-catenin signaling pathways and the transcription factors Snail, ZEB, and P4HA1. …”
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The “One-fifth Rule” with Rollbacks for Self-Adjustment of the Population Size in the (1 + (λ,λ)) Genetic Algorithm by Anton Olegovich Bassin, Maxim Viktorovich Buzdalov, Anatoly Abramovich Shalyto

“…Self-adjustment of parameters can significantly improve the performance of evolutionary algorithms. A notable example is the (1 + (λ,λ)) genetic algorithm, where adaptation of the population size helps to achieve the linear running time on the OneMax problem. …”
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Methods and Strategies for Improving the Novel View Synthesis Quality of Neural Radiation Field by Shun Fang, Ming Cui, Xing Feng, Yanna Lv

“…Neural Radiation Field (NeRF) technology can learn a 3D implicit model of a scene from 2D images and synthesize realistic novel view images. …”
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Mitochondrial Unfolded Protein Response (mtUPR) Activation Improves Pathological Alterations in Cellular Models of Ethylmalonic Encephalopathy by José Manuel Romero-Domínguez, Paula Cilleros-Holgado, David Gómez-Fernández, Rocío Piñero-Pérez, Diana Reche-López, Ana Romero-González, Mónica Álvarez-Córdoba, Alejandra López-Cabrera, Marta Castro De Oliveira, Andrés Rodríguez-Sacristán, Susana González-Granero, José Manuel García-Verdugo, Angeles Aroca, José A. Sánchez-Alcázar

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A conserved pheromone receptor in the American and the Asian palm weevils is also activated by host plant volatiles by Ludvine Brajon, Arthur Comte, Rémi Capoduro, Camille Meslin, Binu Antony, Mohammed Ali Al-Saleh, Arnab Pain, Emmanuelle Jacquin-Joly, Nicolas Montagné

“…Sequences of these two receptors exhibit more than 70 amino acid differences, but modelling of their 3D structures revealed that their putative binding pockets differ by only three amino acids, suggesting possible tuning conservation. …”
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Clade 2.3.4.4b highly pathogenic H5N1 influenza viruses from birds in China replicate effectively in bovine cells and pose potential public health risk by Junlong Xiong, Shiping Ding, Jiangtao Zhou, Yunqi Cui, Xiaona Chen, Lihong Huang, Jiahao Zhang, Wenbao Qi, Ming Liao

“…In February 2024, H5N1 highly pathogenic avian influenza viruses (HPAIVs) of clade 2.3.4.4b were first reported in dairy cows in the USA. …”
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EUROPEAN COURT OF HUMAN RIGHTS JUDGEMENT AS A BASIS FOR REVIEW OF THE NATIONAL COURTS' JUDGEMENT by L. Terekhova

“…Supreme Court puts forward three conditions for the implementation of the revi-sion of the judicial act on a national level, which should be available at the same time: 1) the continuous nature of the adverse effects; 2) the existence of violations of the Convention or gross procedural violations; 3) a causal link between the breach and the consequences.The author point out that the regulation of possible conflicts between the Convention and national legislation is based on cooperation (not confrontation) States and the European Court of Human Rights. …”
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A general theory of the complex pronotum morphology of treehoppers in Smiliinae and its relatives (Hemiptera: Membracidae) and its applicability to other subfamilies by Kanta SUGIURA, Tensho TERANO, Haruhiko ADACHI, Jin HAGIWARA, Keisuke MATSUDA, Kenji NISHIDA, Paul HANSON, Shigeru KONDO, Yasuhiko CHIKAMI, Hiroki GOTOH

“…Treehoppers are characterized by exaggerated and three-dimensionally modified pronotal structures, known as "helmets". …”
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BESO Topology Optimization Driven by an ABAQUS-MATLAB Cooperative Framework with Engineering Applications by Dong Sun, Xudong Yang, Hui Liu, Hai Yang

“…Validation cases including 2D cantilever beams and 3D wheel hubs demonstrate the method’s precision and computational efficiency. …”
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Phylogenetic Analysis of the Mpox Virus in Sub-Saharan Africa (2022–2024) by Millicent Ochieng, Daniel Kiboi, Carolyne Nasimiyu, Eric Osoro, Dorcus C. A. Omoga, Josiah O. Kuja

“…A marked disparity in APOBEC3-associated mutations was observed, with Clade IIb exhibiting significantly higher enrichment than Clade I, suggesting clade-specific host adaptation pressures. …”
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