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1541
The ecological niche and population history shape mosquito population genetics on a group of three Caribbean islands
Published 2025-05-01“…Results Both the genetic diversity and population genetic structure were found to differ strongly between sets of species, leading to a subdivision into three species groups: (1) non-native species with low genetic diversity across all three investigated islands, (2) locally native species with high genetic diversity and closely related haplotypes occurring on different islands and (3) locally native species with high genetic diversity and locally restricted haplotypes. …”
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1543
Systematic genetic characterization of the human PKR kinase domain highlights its functional malleability to escape a poxvirus substrate mimic
Published 2024-11-01“…To systematically explore the evolutionary opportunities available at this dynamic interface, we generated and characterized a library of 426 SNP-accessible nonsynonymous variants of human PKR for their ability to escape inhibition by the model pseudosubstrate inhibitor K3, encoded by the vaccinia virus gene K3L. …”
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1544
A Novel NSGA-III-GKM++ Framework for Multi-Objective Cloud Resource Brokerage Optimization
Published 2025-06-01“…This paper presents NSGA-III-GKM++, an advanced multi-objective optimization model that integrates the NSGA-III evolutionary algorithm with an enhanced K-means++ clustering technique to improve the convergence speed, solution diversity, and computational efficiency. …”
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1545
Author Correction: Development and evolution of Drosophila chromatin landscape in a 3D genome context
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1546
Dilemma and sustainable development strategy of sharing teaching resources for big data majors in universities based on game theory
Published 2024-12-01“…In response to these issues, this article constructed a dynamic information evolution game model based on game theory, which integrated three sub models: static game, incomplete information game, and evolutionary game. …”
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Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer.
Published 2014-01-01“…The Eve expression pattern differs between inbred lines, but the stripe 3 and 7 boundaries seem unaffected by Hb8Δ. The data reveal segregating variation in regulatory elements, which may reflect evolutionary turnover of characterized TFBS due to drift or co-evolution.…”
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1548
Resistance to FLT3 inhibitors involves different molecular mechanisms and reduces new DNA synthesis
Published 2025-03-01“…Acute myeloid leukaemia (AML) is a hard to treat blood cancer. Mutations in FLT3 are common among the genetic aberrations that characterise the cancer. …”
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1549
The Critical Role of Dust on the [O iii] Planetary Nebula Luminosity Function’s Bright-end Cutoff
Published 2025-01-01“…We further show that when our core-mass–nebular extinction law is combined with post-AGB stellar evolutionary models, the result is a large range of population ages where the brightest PNe all have nearly identical [O iii ] luminosities. …”
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1550
Realistic three dimensional fitness landscapes generated by self organizing maps for the analysis of experimental HIV-1 evolution.
Published 2014-01-01“…Self-Organizing Maps (SOM) are a class of Artificial Neural Network (ANN) for the generation of topological ordered maps. Here, three-dimensional (3D) data driven fitness landscapes, derived from a collection of sequences from HIV-1 viruses after "in vitro" passages and labelled with the corresponding experimental fitness values, were created by SOM. …”
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1551
The autoimmune disease risk variant NCF1-His90 is associated with a reduced risk of tuberculosis in women
Published 2025-01-01“…Additionally, healthy individuals with the NCF1 rs201802880 AA genotype had significantly lower circulating white blood cell (5.56 ± 1.78 vs 6.43 ± 1.59, p=0.003) and neutrophil (3.23 ± 1.20 vs 3.74 ± 1.23, p = 0.02) counts compared to those with the GG or GA genotypes, with this difference being more pronounced in women than in men.ConclusionThis study demonstrates that the autoimmune disease-causal NCF1 variant is associated with a protective effect against TB infection.…”
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A study on the financial information disclosure mechanism of digital intelligence based on the participation of four parties
Published 2025-05-01“…Through Matlab simulations, the evolutionary relationships and equilibrium game strategies among the four parties are examined.Conclusion(1) There are four conditional stabilization points in the four-way evolutionary game. …”
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Small mammal communities of Tuva Republic (Southern Siberia, Russia) in a changing climate
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Complete chloroplast genomes of three Pleurozia species and comparative analyses with P. purpurea: codon usage bias and phylogeny
Published 2025-07-01“…The liverwort genus Pleurozia, a morphologically specialized bryophyte group, holds unique taxonomic and evolutionary significance. This study sequenced and assembled the chloroplast genomes of three Pleurozia species (P. acinosa, P. gigantea, and P. subinflata), with genome sizes of 118,233 bp, 118,423 bp, and 118,304 bp, respectively. …”
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Driving forces behind the development of the "Integrated Control and Prevention of Three Highs and Six Diseases" strategy for chronic disease management in Shandong province: a mul...
Published 2025-02-01“…This study elucidates the evolutionary mechanism of the "Integrated Control and Prevention of Three Highs (high blood pressure/glucose/lipids) and Six Diseases (coronary heart disease, stroke, renal lesions, retinal lesions, peripheral neuropathy, and peripheral vascular lesions)" strategy for chronic disease management to explore its future development direction. …”
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A Fusion Method Based on Physical Modes and Satellite Remote Sensing for 3D Ocean State Reconstruction
Published 2025-04-01“…Accurately and timely estimating three-dimensional ocean states is crucial for improving operational ocean forecasting capabilities. …”
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