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6801
Evaluation of psychotropic effects of a novel chromone-containing allylmorpholine derivative in BALB/c mice
Published 2025-06-01“…The study of behavioral changes in Danio rerio after exposure to a new group of substances – chromone-containing allylmorpholines – revealed their ability to exert dose-dependent sedation, and one of the compounds of the series – (E)-4-[3-(6-chloro-4-oxo-4H-chromene-3-yl)-4-cyclohexylallyl]morpholin-4-ium chloride (33a), in addition to sedative, also exerted anxiolytic action at low concentrations. …”
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6802
Divergent transmission dynamics and drug resistance evolution of HIV-1 CRF01_AE and CRF07_BC in Tianjin, China (2013–2022)
Published 2025-05-01“…Phylogenetic analysis indicated that CRF01_AE has a significantly higher evolutionary rate (2.08 × 10⁻3 vs. 1.48 × 10⁻3 substitutions/site/year, P < 0.05), while CRF07_BC demonstrates a greater cluster formation capacity (56.6% vs. 37.1%, P < 0.05). …”
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6803
The GATA-like transcription factor Gat201 determines alkaline-restricted growth in Cryptococcus neoformans
Published 2025-06-01“…RNA-seq analysis shows that Gat201 pathway genes, including co-factors GAT204 and LIV3, are rapidly activated within minutes of inoculating C. neoformans in RPMI media, and strains mutated for GAT204 and, to a lesser extent, LIV3 also show improved growth. …”
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6804
Proteomic study of evolved Pseudomonas aeruginosa strains grown in Staphylococcus aureus- and Klebsiella pneumoniae-conditioned media
Published 2025-07-01“…Both SASn- and KPSn-evolved PA strains positively and negatively regulated H2 and H3-Hcp secretion islands (HSIs) of T6SS, respectively, while the UmMd-evolved strain negatively regulated both H2 and H3-T6SS. …”
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6805
Spatiotemporal evolution and driving force analysis of drought characteristics in the Yellow River Basin
Published 2025-01-01“…Downstream precipitation was 83.9 % and 25.3 % higher than that upstream and midstream, respectively. …”
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6806
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6807
Exploring thoracic aorta ECM alterations in Marfan syndrome: insights into aorta wall structure
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6808
The Convergence of Heavy and Light Seeds to Overmassive Black Holes at Cosmic Dawn
Published 2025-01-01“…The convergence of evolutionary tracks erases seeding information from the mass ratio by z ∼ 4–6. …”
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6809
Some key problems on estimation of height of water-conducting fractured zone for thick coal seam top coal caving
Published 2025-08-01“…In view of the problems and deficiencies to quote empirical formula for top coal caving in thick coal seams, the basis of the empirical formula is analyzed and the applicable conditions, which are large mining areas, single-layer mining thickness of 1~3 m, and cumulative mining thickness not exceed 15 m for coal seam slice mining, are clarified and emphasized. …”
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6810
Investigating the response mechanisms of the intertidal seagrass Zostera japonica to increased UVB radiation through physiological, transcriptomic, and metabolomic analyses
Published 2025-02-01“…Furthermore, its unique evolutionary history has endowed Z. japonica with distinct characteristics that differentiate its response to environmental changes from those of other marine and terrestrial plants. …”
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6811
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6812
A Spectroscopic and Photometric Study of MWC 342 and Its B[e] Phenomenon over the Last 40 Years
Published 2025-05-01“…Several mostly short-term photometric and spectroscopic studies resulted in contradictory conclusions about the nature and evolutionary status of MWC 342. It has been classified as a pre-main-sequence Herbig Be star, an evolved suspected binary system, and a long-period variable star. …”
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6813
Research Status and Prospect of Amphibian Symbiotic Microbiota
Published 2025-03-01“…Finally, the future directions of research on amphibian symbiotic microbiota are examined, with five recommendations presented: (1) Establish a comprehensive sample library and database of amphibians and their symbiotic microbiota to create a solid foundation for scientific research. (2) Explore the coevolutionary paths between amphibians and symbiotic microbiota to clarify the dynamic evolutionary patterns and principles of their interactions. (3) Strengthen research on specific areas of amphibians, especially the microbial communities in the oral cavity and cloaca. (4) Enhance research on the symbiotic microbiota of the Gymnophiona. (5) Strengthen international cooperation to build cross-border research platforms and jointly promote the rapid development of global amphibian symbiotic microbiology. …”
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6814
Dynamically Driven Evolution of Molecular Gas in the Barred Spiral Galaxy M83 Traced by CO J = 2–1/1–0 Line Ratio Variations
Published 2025-01-01“…Azimuthally, it starts from low R _21/10 ≲ 0.7 in the interarm regions and becomes high ≳0.7 in the bar and spiral arms, suggesting that the density and/or kinetic temperature of molecular gas increase by about a factor of 2–3. This evolution is seen even in the parts of spiral arms without star formation, and R _21/10 is often elevated even higher to ∼0.8–1.0 when H ii regions exist in the vicinity. …”
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6815
Prevalence, Molecular Characterization, and Antimicrobial Resistance Profile of Enterotoxigenic <i>Escherichia coli</i> Isolates from Pig Farms in China
Published 2025-03-01“…These relationships suggest evolutionary trade-offs favoring either rapid proliferation or virulence. …”
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6816
The Galactic Population of Magnetars: A Simulation-based Inference Study
Published 2025-01-01“…Population synthesis modeling of the observed dynamical and physical properties of a population is a highly effective method for constraining the underlying birth parameters and evolutionary tracks. In this work, we apply a population synthesis model to the canonical magnetar population to gain insight into the parent population. …”
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6817
Genetic characteristics of the diploid offsprings in potato Cooperation 88 induced by diploid donor IVP101
Published 2024-11-01“…These results reveal the variation and evolutionary characteristics of chloroplast genomes in Solanum plants.…”
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6818
Minimal repeats are ubiquitous sites of crossover and recombination across the human genome
Published 2025-05-01“…Results We found approximately four million AT/TA D3Us and one hundred thousand CG/GC D3Us across the human genome. …”
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6819
Sperm swarm optimization for many objective power flow problems with enhanced performance evaluation in power systems
Published 2025-05-01“…Additional comparisons with OPF models based on FACTS and fuzzy-evolutionary OPF models demonstrate the claimed advantages in practical applications. …”
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6820
Human-in-the-Loop Optimization of the Stiffness and Alignment of a Prosthetic Foot to Reduce the Metabolic Cost of Walking
Published 2025-01-01“…The metabolic cost during the post-test with standard settings was in between the pre-test with standard settings (−6.6%) and the post-test with optimal settings (−4.3%), indicating that part of the decrease in cost could be explained by motor adaptation of the user. …”
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