Suggested Topics within your search.
Suggested Topics within your search.
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2641
Application of Protein Structure Encodings and Sequence Embeddings for Transporter Substrate Prediction
Published 2025-08-01“…In this study, we leverage recent advances in deep learning, such as amino acid sequence embeddings with protein language models (pLMs), highly accurate 3D structure predictions with AlphaFold 2, and structure-encoding 3Di sequences from FoldSeek, for predicting substrates of membrane transporters. …”
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2642
Public antibodies: convergent signatures in human humoral immunity against pathogens
Published 2025-05-01“…In this Minireview, we examine and compare public antibody identification methods, including the identification criteria used based on V(D)J gene usage and similarity in the complementarity-determining region three sequences, and explore the molecular features of public antibodies elicited against common pathogens, including viruses, protozoa, and bacteria. …”
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2643
Neutral markers reveal complex population structure across the range of a widespread songbird
Published 2024-07-01“…Abstract Understanding how both contemporary and historical physical barriers influence gene flow is key to reconstructing evolutionary histories and can allow us to predict species' resilience to changing environmental conditions. …”
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2644
Geological study of sediments from the Negro and Solimões rivers
Published 2025-04-01“… The Amazon is the largest and most complex ecosystem on the planet, and its entire evolutionary history was influenced by the dynamics of the Amazon River System. …”
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2645
Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery
Published 2019-01-01“…We focus on the applications of comparative genomics, metabolomics, evolutionary bioinformatics and structural proteomics to identify potential drug targets. …”
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2646
CrySPAI: A New Crystal Structure Prediction Software Based on Artificial Intelligence
Published 2025-03-01“…The software consists of three key modules, an evolutionary optimization algorithm (EOA) that searches for all possible crystal structure configurations, density functional theory (DFT) that provides the accurate energy values for these structures, and a deep neural network (DNN) that learns the relationship between crystal structures and their corresponding energies. …”
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2647
An adaptive differential evolution algorithm based on adaptive evolution strategy and diversity enhancement
Published 2025-09-01“…Second, we introduce a novel individual ranking factor that divides the generation of the scaling factor into three distinct phases, thereby optimizing balanced exploration and exploitation throughout the evolutionary process. …”
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2648
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2649
Comparative analysis of the global innovation index combining the graph visualization and topological data analysis approaches
Published 2025-07-01“… This study analyzes the Global Innovation Index (GII) of the 100 most innovative countries in 2022 and 2023, applying the Fruchterman-Reingold algorithm to obtain a spatial distribution of the data and utilizing persistent homology with Vietoris-Rips complexes at three scales (ε = 0.3, 1.0, and 1.5) to form connected components or structures. …”
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2650
Application of Hybrid MOPSO Algorithm to Optimal Reactive Power Dispatch Problem Considering Voltage Stability
Published 2014-01-01“…This problem is formulated as a challenging nonlinear constrained multiobjective optimization problem considering three objectives, that is, power losses minimization, voltage profile improvement, and voltage stability enhancement simultaneously. …”
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2651
Empirical study on the evolution of telecom fraud risks driven by artificial intelligence generated content
Published 2025-05-01“…The evolution patterns of telecom fraud risks driven by AIGC were categorized into three types: the long-chain type evolution pattern systematically identifies complete risk events and their inter-event evolutionary trajectories within cases, while investigation of the star-shaped and composite type evolution patterns enable recognition of divergent risk behavioral patterns and localization of core risk event nodes across homogeneous case clusters, there by establishing a theoretical foundation for developing scientifically rational governance strategies in telecom fraud countermeasures.…”
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2652
Divergence of the bZIP Gene Family in Strawberry, Peach, and Apple Suggests Multiple Modes of Gene Evolution after Duplication
Published 2015-01-01“…The comparative analysis of bZIP genes in three species provides information on the evolutionary fate of bZIP genes in apple and peach after they diverged from strawberry.…”
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2653
Genomic insights on heterogeneous resistance to vancomycin and teicoplanin in Methicillin-resistant Staphylococcus aureus: A first report from South India.
Published 2019-01-01“…Significant pbp2 upregulation was noted in three TR-MRSA strains, which had teicoplanin MICs of 16 or 32 μg/ml, whilst significant pbp4 downregulation was not noted in these strains. …”
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2654
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2655
Classification, Functions, Development and Outlook of Photoanode Block Layer for Dye-Sensitized Solar Cells
Published 2025-03-01“…We categorize block layer architectures into three distinct configurations: single layer, doped layer, and multilayer structures. …”
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2656
Global agricultural trade network characteristics and its influencing factors
Published 2025-08-01“…Abstract This study investigates the evolutionary process of the global agricultural trade network and identifies key influencing factors. …”
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2657
Chromosomal periodicity and positional networks of genes in Escherichia coli
Published 2010-05-01“…This finding generates new questions on evolutionary pressures imposed on the chromosome. Our methodological approach is based on single genome analysis. …”
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2658
Rapid and recent diversification patterns in Anseriformes birds: Inferred from molecular phylogeny and diversification analyses.
Published 2017-01-01“…Furthermore, diversification analyses showed that, after a long period of constant diversification, the median initial speciation rate was accelerated three times, and finally increased to approximately 0.3 sp/My. …”
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2659
Extending Long‐Term Avian Studies Alters Temporal and Climate‐Driven Trend Conclusions
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2660
Using principal component analysis to identify the component affecting skull weight of Japanese Quail
Published 2025-03-01“…The analysis extracted three principal components for both sexes, explaining 52.76% of the variance in males and 56.52% in females. …”
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