Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors. by Anna Cichonska, Balaguru Ravikumar, Elina Parri, Sanna Timonen, Tapio Pahikkala, Antti Airola, Krister Wennerberg, Juho Rousu, Tero Aittokallio

“…To evaluate its performance, we first predicted unmeasured binding affinities in a large-scale kinase inhibitor profiling study, and then experimentally tested 100 compound-kinase pairs. …”
Get full text

Multidetector computed tomography to predict heavy bleeding and need for angiographic embolization in patients with postpartum hemorrhage by H.M. Kim, J.Y. Lee, W.J. Seong

“…Purpose: This retrospective study was designed to evaluate the usefulness of multidetector computed tomography (MDCT) in the identification of heavy bleeding, as a determinant of angiographic embolization (AE) in patients with postpartum hemorrhage (PPH). …”
Get full text

Computational Analysis of Blended Winglet Designs to Reduce the Wake Turbulence on the Airbus A380 Wingtip by Joseph Ciano Pinto, Siva Marimuthu, Parvathy Rajendran, Manikandan Natarajan, Rajadurai Murugesan

“…With the use of modern computational fluid dynamics tools, the current A380 winglets’ performance was evaluated to identify the level of lift, drag and wake vortex patterns. …”
Get full text

Association of non-Alcoholic Fatty Liver Disease with Urolithiasis detected on non-Contrast Computed Tomography by Kamil Abdulmajeed Ahmed, Saeed Nadhim Younis

“… Background & Objectives: We aimed to assess whether there is an association between urolithiasis and non-alcoholic fatty liver disease using non-enhanced computed tomography. Methods :This is a case control study done from October to December 2019, a total of 284 non-contrasts CT scans of reviewed. …”
Get full text

CONTRAST-ENHANCED COMPUTED TOMOGRAPHIC CHOLANGIOGRAPHY IN DIFFERENTIAL DIAGNOSIS OF THE MALIGNANT AND BENIGN CAUSES OF BILIARY OBSTRUCTION by V. V. Zarubin, A. P. Kurazhov, V. D. Zavadovskaja, O. V. Rodionova, O. S. Tonkikh, I. Yu. Klinovitskiy, M. A. Zorkaltsev, V. I. Haritonkin

“…In the world literature, there are few reports on the assessment of the diagnostic potential of multispiral computed tomography under conditions of direct contrasting of the biliary tree using endoscopic retrograde cholangiopancreatography, percutaneous transhepatic cholangiography, or through pre-installed palliative drainage in the bile ducts. …”
Get full text

Enhanced EEG signal classification in brain computer interfaces using hybrid deep learning models by Abir Das, Saurabh Singh, Jaejeung Kim, Tariq Ahamed Ahanger, Anil Audumbar Pise

“…Abstract Brain-computer interfaces (BCIs) establish a communication pathway between the human brain and external devices by decoding neural signals. …”
Get full text

Optimizing Esophageal Cancer Diagnosis with Computer-Aided Detection by YOLO Models Combined with Hyperspectral Imaging by Wei-Chun Weng, Chien-Wei Huang, Chang-Chao Su, Arvind Mukundan, Riya Karmakar, Tsung-Hsien Chen, Amey Rajesh Avhad, Chu-Kuang Chou, Hsiang-Chen Wang

Get full text

Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach by Mohibullah Shah, Farva Sitara, Asifa Sarfraz, Muhammad Shehroz, Tehreem Ul Wara, Asia Perveen, Najeeb Ullah, Aqal Zaman, Umar Nishan, Sarfraz Ahmed, Riaz Ullah, Essam A. Ali, Suvash Chandra Ojha

Get full text

Computational analysis of Annona muricata phytochemicals for targeted modulation of endocrine networks in polycystic ovary syndrome by Babatunji Emmanuel Oyinloye, Oluwaseun Emmanuel Agboola, Aderonke Moyosola Ayeni, Oluwatoyin Mary Oyinloye, Samuel Sunday Agboola, Olajumoke Tolulope Idowu, Makhosazana Siduduzile Mathenjwa-Goqo, Olutunmise Victoria Owolabi, Bolajoko Idiat Ogunyinka, Foluso Oluwagbemiga Osunsanmi, Basiru Olaitan Ajiboye, Olaposi Idowu Omotuyi

“…Molecular modeling and evaluations were done on three protein receptors involved in hormonal imbalance. …”
Get full text

A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank by Ana Torralbo, Jonathan M. Davitte, Damien C. Croteau-Chonka, Cai Ytsma, Chris Tomlinson, Natalie K. Fitzpatrick, Sheng-Chia Chung, Ghazaleh Fatemifar, Adrian S. Cortes, Tom G. Richardson, Matthew Barclay, Julia Carrasco-Zanini, Chris Finan, Harry Hemingway, Aroon D. Hingorani, Valerie Kuan, Claudia Langenberg, Georgios Lyratzopoulos, R. Thomas Lumbers, Maik Pietzner, Anoop D. Shah, Johan H. Thygesen, Natalie Zelenka, John C. Whittaker, Margaret G. Ehm, Spiros Denaxas

“…As a result, the current phenotyping landscape is fragmented. We developed a computational framework to harmonize electronic health record (EHR) data, participant questionnaires, and clinical registry information, defining 313 disease phenotypes among 502,356 UK Biobank (UKB) participants. …”
Get full text

A Robust Image Encryption Protocol for Secure Data Sharing in Brain Computer Interface Applications by Sunil Prajapat, Pankaj Kumar, Kashish Chaudhary, Kranti Kumar, Gyanendra Kumar, Ali Kashif Bashir

“…Brain-computer interface (BCI) technology has emerged as a transformative means to link human neural activity with electronic devices. …”
Get full text

Causes and Management of Chest Computed Tomography Lesions Progression in Pulmonary Tuberculosis during Antituberculosis Treatment by Shuangyin Yang, Yanmei Feng, Kuiliang Yang, Jie Pu, Pu Wang

“…Background: Even with early antituberculosis (TB) treatment, some patients with pulmonary TB (PTB) may experience progression of chest computed tomography (CT) lesions. However, there is limited information on the causes and management of this progression during treatment. …”
Get full text

Comparing different intestinal contrast agents in multislice computed tomography enterography examination for Crohn’s disease by Li Jiayan, Zhang Junmei, Cao Di

“…[Objectives] To compare different intestinal contrast agents in multislice computed tomography enterography (MSCTE) examination for Crohn’s disease (CD). …”
Get full text

Student Critical Self-Reflection and Perceptions of Video-Based Pro-Section Computer-Assisted Instruction by Emily S. Ho, Erica Dove, Lorna Aitkens, Andrea Duncan, Anne M. R. Agur

“…Introduction The cost, high resource demands, and psychological significance of in-person cadaveric labs are barriers to their use. Computer-assisted instruction (CAI) of gross anatomy is widely available as an alternative option. …”
Get full text

Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography by Anh T. Tran, Dmitriy Desser, Tal Zeevi, Gaby Abou Karam, Julia Zietz, Andrea Dell’Orco, Min-Chiun Chen, Ajay Malhotra, Adnan I. Qureshi, Santosh B. Murthy, Shahram Majidi, Guido J. Falcone, Kevin N. Sheth, Jawed Nawabi, Seyedmehdi Payabvash

Get full text

An Efficient Optimal CapsNet Model-Based Computer-Aided Diagnosis for Gastrointestinal Cancer Classification by Fahdah A Almarshad, Prasanalakshmi Balaji, Liyakathunisa Syed, Eman Aljohani, Santhi Muttipoll Dharmarajlu, Thavavel Vaiyapuri, Nourah Ali AlAseem

Get full text

A Novel SSVEP Brain-Computer Interface System Based on Simultaneous Modulation of Luminance and Motion by Meng Li, Ning Li, Xiaorong Gao, Ruijuan Ma, Jianwei Dong, Xiaogang Chen, Hongyan Cui

“…Steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) have received significant attention owing to their high information transfer rate (ITR) and low training requirements. …”
Get full text

Drug Repurposing for Targeting ISL LIM Homeobox 2 in Treatment of Endometriosis: A Computational Study by Soodeh Mahdian, Raha Favaedi, Gelareh Mikaeeli, Ashraf Moini, Maryam Shahhoseini

“…This study aims to repurpose drugs to target ISL2 for endometriosis treatment.Materials and Methods: In this computational study, we sought to confirm that ISL2 is an appropriate target for this study by evaluating its expression in the endometrial tissues of patients diagnosed with endometriosis, as well as in tissues from a control group of healthy women. …”
Get full text

Amplitude Modulation Depth Coding Method for SSVEP-Based Brain–Computer Interfaces by Ruxue Li, Zhenyu Wang, Xi Zhao, Guiying Xu, Honglin Hu, Ting Zhou, Tianheng Xu

“…In steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs), the limited availability of frequency resources inherently constrains the scale of the instruction set, presenting a substantial challenge for efficient communication. …”
Get full text

Effect of brain computer interface combined with acupuncture therapy on motor and cognitive function in stroke patients by LU Jie, WANG Ping, LI Hongyan, WANG Jinfeng, LI Xiang, WANG Chunli

“…Objective To investigate the effect of a brain computer interface combined with acupuncture therapy on the recovery of motor function, cognitive function and daily living ability in stroke patients. …”
Get full text