Restored Collagen VI Microfilaments Network in the Extracellular Matrix of CRISPR-Edited Ullrich Congenital Muscular Dystrophy Fibroblasts by Daniela Benati, Eleonora Cattin, Federico Corradi, Tommaso Ferrari, Eleonora Pedrazzoli, Clarissa Patrizi, Matteo Marchionni, Roberto Bertorelli, Veronica De Sanctis, Luciano Merlini, Alessandra Ferlini, Patrizia Sabatelli, Francesca Gualandi, Alessandra Recchia

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Grid-Based Software for Quantification of Diabetic Retinal Nonperfusion on Ultra-Widefield Fluorescein Angiography by Amro Omari, Caitlyn Cooper, Eric B. Desjarlais, Maverick Cook, Maria Fernanda Abalem, Chris A. Andrews, Katherine Joltikov, Rida M. Khan, Andy Chen, Andrew DeOrio, Thomas W. Gardner, Yannis M. Paulus, K. Thiran Jayasundera

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Detection of litchi fruit maturity states based on unmanned aerial vehicle remote sensing and improved YOLOv8 model by Changjiang Liang, Changjiang Liang, Dandan Liu, Dandan Liu, Weiyi Ge, Weiyi Ge, Wenzhong Huang, Wenzhong Huang, Yubin Lan, Yubin Lan, Yubin Lan, Yongbing Long, Yongbing Long, Yongbing Long, Yongbing Long

“…The weight, parameter count, and computational load of the model were reduced by 17.5%, 19.0%, and 9.9%, respectively. …”
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A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab by Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang

“…Despite the wide application of low‐dose computed tomography (LDCT) in the early screening of LUAD, the identification of malignant pulmonary nodules by it remains a challenge. …”
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Locally advanced cholangiolocellular carcinoma successfully treated with curative resection after downsizing chemotherapy: a case report by Yuto Hozaka, Yota Kawasaki, Satoshi Iino, Tetsuya Idichi, Yuki Hirase, Kiyonori Tanoue, Yuko Mataki, Hiroshi Kurahara, Kosei Maemura, Takaaki Arigami, Shinichi Ueno, Shoji Natsugoe, Takao Ohtsuka

“…After a total of 10 courses of chemotherapy over 10 months the tumor was shown to be reduced in size by computed tomography imaging, and she was referred to our department for surgical resection. …”
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Dynamic Retrieval Augmented Generation of Ontologies using Artificial Intelligence (DRAGON-AI) by Sabrina Toro, Anna V. Anagnostopoulos, Susan M. Bello, Kai Blumberg, Rhiannon Cameron, Leigh Carmody, Alexander D. Diehl, Damion M. Dooley, William D. Duncan, Petra Fey, Pascale Gaudet, Nomi L. Harris, Marcin P. Joachimiak, Leila Kiani, Tiago Lubiana, Monica C. Munoz-Torres, Shawn O‘Neil, David Osumi-Sutherland, Aleix Puig-Barbe, Justin T. Reese, Leonore Reiser, Sofia MC. Robb, Troy Ruemping, James Seager, Eric Sid, Ray Stefancsik, Magalie Weber, Valerie Wood, Melissa A. Haendel, Christopher J. Mungall

“…Notably, evaluators with the highest level of confidence in a domain were better able to discern flaws in AI-generated definitions. …”
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Leveraging Machine Learning for Accurate and Fast Stellar Mass Estimation of Galaxies by Vahid Asadi, Akram Hasani Zonoozi, Hosein Haghi, Fatemeh Abedini, Atousa Kalantari, Marziye Jafariyazani, Nima Chartab

“…However, this approach can be computationally intensive and time-consuming, particularly for large data sets. …”
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Mosaic vaccine design targeting mutational spike protein of SARS- CoV-2: An immunoinformatics approach by Ysrafil Ysrafil, Arlan K. Imran, Prisca Syafriani Wicita, Vyani Kamba, Fihrina Mohamad, Ismail Ismail, Ayyub Harly Nurung, Noviyanty Indjar Gama, Sari Eka Pratiwi, Indwiani Astuti, Firzan Nainu, Talha Bin Emran

“…Various immunoinformatics tools were utilized to provide the highest potential for a mosaic vaccine that could activate immune responses against COVID-19. Results: The evaluation of the constructed vaccine revealed that it is antigenic and immunogenic as well as nonallergenic. …”
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Targeted lipidomics dataset of central nervous system and plasma from mice with experimental autoimmune encephalomyelitisMendeley Data by Jörn Lötsch, Irmgard Tegder, Natasja de Bruin, Dominique Thomas, Gerd Geisslinger

“…It supports statistical and machine learning applications and enables the evaluation of data augmentation strategies, including statistical and generative AI approaches. …”
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Association of socioeconomic status on return to work following primary total hip arthroplasty: a Danish population-based cohort study on 9,431 patients from 2008–2018 by Peter Alsing, Julie B Pajaniaye, Martin G Stisen, Søren Overgaard, Erzsébet Horváth-Puhó, Inger Mechlenburg, Alma B Pedersen

“…Work status information before and after THA was obtained from the Danish Register for Evaluation of Marginalization. We computed cumulative incidence of RTW up to 24 months after THA. …”
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Artificial intelligence analysis of thermal energy for convectively heated ternary nanofluid flow in radiated channel considering viscous dissipations aspects by Hamid Qureshi, Amjad Ali Pasha, Muhammad Asif Zahoor Raja, Zahoor Shah, Salem Algarni, Talal Alqahtani, Waqar Azeem Khan, Moinul Haq

“…Dataset generated from Python and Mathematica is filtered and embedded into LMNNA for evaluation and comparison of results.Temperature and flow rate profile are analyzed against variations in sundry characteristics. …”
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Modelling emission and transport of key components of primary marine organic aerosol using the global aerosol–climate model ECHAM6.3–HAM2.3 by A. Leon-Marcos, M. Zeising, M. van Pinxteren, S. Zeppenfeld, A. Bracher, A. Bracher, E. Barbaro, A. Engel, M. Feltracco, I. Tegen, B. Heinold

“…Based on the most comprehensive evaluation to date, the computed levels of biomolecules in the ocean and species-resolved PMOA concentrations are compared with ground-based measurements across the globe. …”
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Effects of hybrid emergency department on extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients by Takashi Nakata, Daisuke Kudo, Yasushi Kudo, Atsushi Tanikawa, Ken Katsuta, Hiroyuki Ohbe, Masakazu Kobayashi, Akira Suda, Satoshi Yasuda, Shigeki Kushimoto

“…Background: Hybrid emergency department (ED), which are equipped with fluoroscopy and computed tomography has been developed in Japan as a novel emergency care room. …”
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Percutaneous implantation of self-expandable aortic valve in high risk patients with severe aortic stenosis: The first experiences in Serbia by Nedeljković Milan A., Beleslin Branko, Tešić Milorad, Vukčević Vladan, Stanković Goran, Stojković Siniša, Orlić Dejan, Bilbija Ilija, Matković Miloš, Simić Tijana, Menković Nemanja, Mrdović Igor, Ussia Gian Paolo, Perišić Zoran, Babić Momčilo

“…Pre-procedure screening included detailed clinical and echocardiographic evaluation, coronary angiography and computed tomography scan. …”
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Performance of CAD4TB artificial intelligence technology in TB screening programmes among the adult population in South Africa and Lesotho by Nonhlanhla Nzimande, Keelin Murphy, Klaus Reither, Shannon Bosman, Irene Ayakaka, Tracy R. Glass, Fiona Vanobberghen, Bart K.M. Jacobs, Aita Signorell, Jabulani Ncayiyana

“…Summary: There is growing evidence of the performance accuracy and potential impact of Computer-Aided Diagnosis (CAD) products in TB-burdened settings. …”
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Machine learning, clinical-radiomics approach with HIM for hemorrhagic transformation prediction after thrombectomy and treatment by Sheng Hu, Junyu Liu, Jiayi Hong, Yuting Chen, Ziwen Wang, Jibo Hu, Shiying Gai, Xiaochao Yu, Jingjing Fu

“…BackgroundThis study aimed to develop a clinical-radiomics model using hyperattenuated imaging markers (HIM), characterized by hyperattenuation on head non-contrast computed tomography immediately after thrombectomy, to predict the risk of hemorrhagic transformation (HT) in patients undergoing endovascular mechanical thrombectomy (MT).MethodsA total of 159 consecutive patients with HIM were screened immediately after MT for inclusion. …”
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Impact of the no-touch harvesting technique on the vessel diameter of saphenous vein grafts for coronary artery bypass graftingCentral MessagePerspective by Hiroshi Kurazumi, MD, PhD, Ryo Suzuki, MD, PhD, Ryosuke Nawata, MD, Toshiki Yokoyama, MD, Sarii Tsubone, MD, Akihito Mikamo, MD, PhD, Kimikazu Hamano, MD, PhD

“…The diameter mismatch between the saphenous vein grafts and the coronary artery at the anastomotic site was also measured; preoperative diameter was measured using ultrasound imaging, and the postoperative diameter was measured using electrocardiogram-gated enhanced computed tomography. Results: A total of 135 saphenous vein grafts (66 and 69 grafts in the conventional and no-touch groups, respectively) were evaluated for postoperative patency. …”
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In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients with COPD Using Functional Respiratory Imaging by Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J

“…Dave Singh,1 Nicolas Roche,2,3 Libo Wu,4 Hosein Sadafi,5 Jan De Backer,6,7 Navid Monshi Tousi,5 Jonathan Marshall8 1Respiratory Research Group, University of Manchester, Medicines Evaluation Unit, Manchester University National Health Service Foundation Trust, Manchester, UK; 2Department of Respiratory Medicine, Hospital Cochin, APHP Centre, Paris, France; 3Université Paris Cité, Institut Cochin, U1016, Paris, France; 4Product Development Operations, AstraZeneca, Durham, NC, USA; 5Department of Computational Engineering, FLUIDDA NV, Kontich, Belgium; 6FLUIDDA NV, Kontich, Belgium; 7Department of Respiratory Medicine, University of Antwerp, Antwerp, Belgium; 8Global Medical Respiratory, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UKCorrespondence: Jonathan Marshall, Global Medical Respiratory, BioPharmaceuticals Medical, AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CV2 0AA, UK, Tel +44 20 3749 5000, Email jonathan.marshall1@astrazeneca.comIntroduction: Inhalation is the foundational route for administering pharmacological treatments for chronic obstructive pulmonary disease (COPD). …”
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Unveiling the antiviral inhibitory activity of ebselen and ebsulfur derivatives on SARS-CoV-2 using machine learning-based QSAR, LB-PaCS-MD, and experimental assay by Silpsiri Sinsulpsiri, Yuji Nishii, Qing-Feng Xu-Xu, Masahiro Miura, Patcharin Wilasluck, Kanokwan Salamteh, Peerapon Deetanya, Kittikhun Wangkanont, Aphinya Suroengrit, Siwaporn Boonyasuppayakorn, Lian Duan, Ryuhei Harada, Kowit Hengphasatporn, Yasuteru Shigeta, Liyi Shi, Phornphimon Maitarad, Thanyada Rungrotmongkol

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Stacked Ensemble Learning for Classification of Parkinson’s Disease Using Telemonitoring Vocal Features by Bolaji A. Omodunbi, David B. Olawade, Omosigho F. Awe, Afeez A. Soladoye, Nicholas Aderinto, Saak V. Ovsepian, Stergios Boussios

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