Thiazolo-pyridopyrimidines: An in silico evaluation as a lead for CDK4/6 inhibition, synthesis and cytotoxicity screening against breast cancer cell lines by Chaithra R Shetty, C. S. Shastry, Parasuraman P, Srinivas Hebbar

“…Methods: We designed and synthesized a range of substituted thiazolo-pyridopyrimidines (4a-p). Computational ADME/T analysis and molecular docking were performed using the crystal structure of CDK4/6. …”
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In vivo evaluation of a new hybrid graft using retrograde visceral perfusion for thoracoabdominal aortic repair in an animal modelCentral MessagePerspective by Sabine Wipper, MD, Harleen K. Sandhu, MD, MPH, Tilo Kölbel, MD, Anthony L. Estrera, MD, Constantin Trepte, MD, Christoph Behem, MD, Charles C. Miller, III, PhD, E. Sebastian Debus, MD

“…To improve technical feasibility and safety, the new Thoracoflo graft, consisting of a proximal stent graft connected to a 7-branched abdominal prosthesis, was evaluated in a pig model for technical feasibility testing, before implantation in humans. …”
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Digitally deployed, GP remote consultation video intervention that aims to reduce opioid prescribing in primary care: protocol for a mixed-methods evaluation by Nick Hex, Christopher Price, Yu Fu, Ben Allen, Tracy Finch, Denis Martin, Cormac G Ryan, Alan M Batterham, Niki Jones, Ewan Maule

“…The intervention arm will comprise 50 General Practitioner (GP) Practices using System 1 (a clinical computer system hosting the intervention) who will deliver the video to their patients via text message. …”
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A comparison of CXR-CAD software to radiologists in identifying COVID-19 in individuals evaluated for Sars CoV-2 infection in Malawi and Zambia. by Sam Linsen, Aurélie Kamoun, Andrews Gunda, Tamara Mwenifumbo, Chancy Chavula, Lindiwe Nchimunya, Yucheng Tsai, Namwaka Mulenga, Godfrey Kadewele, Eunice Nahache Kajombo, Veronica Sunkutu, Jane Shawa, Rigveda Kadam, Matthew Arentz

“…AI based software, including computer aided detection software for chest radiographs (CXR-CAD), was developed during the pandemic to improve COVID-19 case finding and triage. …”
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Photon counting CT vs. flat-panel CT in the evaluation of enhancement patterns in chronic subdural hematoma after middle meningeal artery embolization by Christoph J. Maurer, Lars Behrens, Stefan Schiele, Mahmoud Zaki, Guilherme Quint, Christina Wolfert, Björn Sommer, Franz J. Stangl, Ansgar Berlis

“…This study investigates whether specific enhancement patterns can predict radiological outcomes and evaluates the utility of photon-counting computed tomography (PCCT) in distinguishing contrast enhancement from hemorrhage.MethodsWe retrospectively analyzed 105 cSDHs imaged with either PCCT or flat-panel CT immediately after embolization. …”
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CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials by Dimitrios Zouraris, Angelos Mavrogiorgis, Andreas Tsoumanis, Laura Aliisa Saarimäki, Giusy del Giudice, Antonio Federico, Angela Serra, Dario Greco, Ian Rouse, Julia Subbotina, Vladimir Lobaskin, Karolina Jagiello, Krzesimir Ciura, Beata Judzinska, Alicja Mikolajczyk, Anita Sosnowska, Tomasz Puzyn, Mary Gulumian, Victor Wepener, Diego S.T. Martinez, Romana Petry, Naouale El Yamani, Elise Rundén-Pran, Sivakumar Murugadoss, Sergey Shaposhnikov, Vasileios Minadakis, Periklis Tsiros, Harry Sarimveis, Eleonora Marta Longhin, Tanima SenGupta, Ann-Karin Hardie Olsen, Viera Skakalova, Peter Hutar, Maria Dusinska, Anastasios G. Papadiamantis, L. Cristiana Gheorghe, Katie Reilly, Emilie Brun, Sami Ullah, Sebastien Cambier, Tommaso Serchi, Kaido Tämm, Candida Lorusso, Francesco Dondero, Evangelos Melagrakis, Muhammad Moazam Fraz, Georgia Melagraki, Iseult Lynch, Antreas Afantitis

“…The CompSafeNano project, a Research and Innovation Staff Exchange (RISE) project funded under the European Union's Horizon 2020 program, aims to advance the safety and innovation potential of nanomaterials (NMs) by integrating cutting-edge nanoinformatics, computational modelling, and predictive toxicology to enable design of safer NMs at the earliest stage of materials development. …”
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Evaluation and mitigation methods for virtual reality motion sickness(面向虚拟现实晕动症的评估与缓解方法) by 顾展滔(GU Zhantao), 丁玎(DING Ding), 陈亦婷(CHEN Yiting), 张文杰(ZHANG Wenjie)

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High‐Definition and Autofluorescence Bronchoscopic Imaging for Evaluating Epithelial Changes in Squamous Cell Lung Cancer After Neoadjuvant Immunochemotherapy: A Case Report by Kei Morikawa, Koji Kojima, Hideki Marushima, Yoshiya Sugiura, Junki Koike, Hisashi Saji, Masamichi Mineshita

“…ABSTRACT In recent years, perioperative immune checkpoint inhibitors have become indicated for early‐stage lung cancer, emphasizing the importance of high‐resolution endoscopic evaluation of preoperative drug therapy. At the initial evaluation, a male patient in his 60s presented with a primary lesion obstructing the right upper lobe bronchus. …”
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To determine the efficacy of ultrasonography in the evaluation of bone fill at the regenerate site for mandibular distraction osteogenesis over clinical and radiographic assessment... by Neelam Andrade, Neha Aggrawal, Guruprasad Jadhav, Vyankatesh Sahu, Paul C. Mathai

“…Until date conventional radiographs and computed tomography are the preferred diagnostic modalities to monitor the distraction osteogenesis regenerate. …”
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Pythagorean fuzzy N-bipolar soft sets-based multi-criteria decision-making framework for sustainability evaluation and risk assessment in manufacturing industries by Maha M. Saeed, Sagvan Y. Musa, Baravan A. Asaad, Zanyar A. Ameen

“…Abstract Sustainability evaluation in manufacturing industries is increasingly vital for promoting responsible growth and long-term competitiveness amid environmental, social, and economic challenges. …”
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Evaluating Petrophysical Properties Using Digital Rock Physics Analysis: A CO₂ Storage Feasibility Study of Lithuanian Reservoirs by Shruti Malik, Pijus Makauskas, Ravi Sharma, Mayur Pal

“…As the global concern over greenhouse gas emissions grows, CO₂ storage in deep saline aquifers and depleted reservoirs has become crucial for climate change mitigation. This study evaluates the feasibility of Lithuanian deep saline aquifers, specifically, Syderiai and Vaskai, for effective CO₂ storage. …”
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Energy Urban Domain: Personalized Evaluation of Expert and Non-Expert Stakeholder Interaction With Artificial Intelligence Through ChatGPT Using the VIRTSI Model by George A. Tsihrintzis, Elissaios Sarmas, Vangelis Marinakis, Dimitrios P. Panagoulias, Evangelia-Aikaterini Tsichrintzi, Maria Virvou

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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening by Chun‐Lin Yang, Yi‐Wen Wu, Huang‐Ju Tu, Yun‐Hsuan Yeh, Tony Eight Lin, Tzu‐Ying Sung, Mu‐Chun Li, Shih‐Chung Yen, Jui‐Hua Hsieh, Ming‐Chin Yu, Sen‐Yung Hsieh, Hsing‐Pang Hsieh, Shiow‐Lin Pan, Kai‐Cheng Hsu

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Evaluation of Organ Dose following Radiotherapy of the Brain using Bio-Based Head Phantom Made From Soy-Lignin bonded Rhizophora spp. by Siti Hajar binti Zuber, Nurul Ab. Aziz Hashikin, Nor Hafizah Ishak, Nursyatina Abdul Raof, Mohd Fahmi Mohd Yusof, Mohd Zahri Abdul Aziz

“…The custom-made head phantom was fabricated using Rhizophora spp. bonded with soy flour and lignin, and its potential as phantom material was evaluated in previous studies. Organs at risk and planning target volume were identified using the treatment planning system, which was guided by computed tomography raw images. …”
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Quantitative Evaluation of Marginal and Internal Fit of CAD/CAM Ceramic Crown Restorations Obtained by Model Scanner, Intraoral Scanner, and Different CBCT Scans by Bora Akat, Ayben Şentürk, Mert Ocak, Mehmet Ali Kılıçarslan, Kaan Orhan, Merve Önder, Fehmi Gönüldaş

“…(1) Background: This study aimed to evaluate the marginal and internal fit of ceramic crowns produced by various digital methods using microcomputed tomography (MCT) imaging. (2) Methods: The ceramic crown preparation was performed on typodont maxillary first premolar. …”
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SE-CapsNet: Automated evaluation of plant disease severity based on feature extraction through Squeeze and Excitation (SE) networks and Capsule networks by Shradha Verma, Anuradha Chug, Ravinder P. Singh, Amit P. Singh, Dinesh Singh

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Evaluation of the vacuum effect on headspace solid-phase microextraction of volatile organic compounds from aqueous samples using finite element analysis modeling by Bulat Kenessov, Aset Muratuly

“…This research was aimed at the evaluation of the possible effect of vacuum on the equilibration time and extracted amounts of analytes with various HLC and fiber coating-headspace distribution constants (Kfh) using the computational model recently developed in COMSOL Multiphysics® software. …”
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Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties by Keisuke Iida, Masayuki Tera, Takatsugu Hirokawa, Kazuo Shin-ya, Kazuo Nagasawa

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Evaluation of the Performance of a YOLOv10-Based Deep Learning Model for Tooth Detection and Numbering on Panoramic Radiographs of Patients in the Mixed Dentition Period by Ramazan Berkay Peker, Celal Oguz Kurtoglu

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A Comprehensive Approach for Performance Evaluation in Petrochemical Industry: Integrating Sustainable Balanced Scorecard, Dynamic Network DEA, and DEMATEL in a Neutrosophic Enviro... by Hasan Abedifar, Bijan Rahmani Parchikolaei, Seyyed Mohammad Hadji Molana, Mahnaz Ahadzadeh Namin

“…Sustainability is increasingly vital in modern industries, necessitating comprehensive evaluation frameworks that assess both efficiency and sustainability. …”
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