Bioinformatics and immunoinformatics assisted multiepitope vaccine construct against Burkholderia anthina by Maha A. Alshiekheid, Ali M. Dou, Mohammad Algahtani, Wafa Abdullah I. Al-Megrin, Yaseer Ali Alhawday, Arwa Essa Alradhi, Khulud Bukhari, Basmah F. Alharbi, Ahmed N. Algefary, Basmah Awwadh Alhunayhani, Khaled S. Allemailem

“…The designed vaccine construct was evaluated for its physiochemical properties analysis in which we reported that the vaccine construct comprises 216 amino acids with a molecular weight of 22.37499 kilo Dalton, 15.55 instability index (II) is computed, and this classifies that the vaccine construct is properly stable. …”
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Commiphora myrrha resin extract-modulated cytochrome P-450 2C9 enzyme expression in cultured Hep G2 cells is associated with resin extract-derived metabolites binding to Pregnane X... by Amani Alsharidah, Zeyad Alehaideb, Sahar S. Alghamdi, Rasha S. Suliman, Saleh Althenayyan, Feras Almourfi, Bader Hazazi, Aljawharah Almogren, Abeer Al Tuwaijri, Mohamed Boudjelal, Afrah Alkhuriji, Sabine Matou-Nasri

“…CYP 2C9 gene and protein expression levels were evaluated using reverse transcription-quantitative polymerase chain reaction and Western blot. …”
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Thymic characteristics in patients with autoimmune diseases: a multicentre radiological observational studyResearch in context by Haoxiao Chang, Junqiang Yan, Anxin Wang, Ningning Wang, Peng Liu, Yemin Shi, Xin Zhao, Jinqiao Zhu, Yuan Cai, Xue Xia, Yunyi Hao, Shiyi Yin, Jing Wang, Xinli Wang, Lina Sun, Jia Ma, Xiaoyu Huang, Haonan Guan, De-Cai Tian, Kaibin Shi, Ganqin Du, Wenhao Huang, Guoyan Qi, Hao Li, Yongjun Wang, Fu-Dong Shi, Zhang Zhang, Wei-Na Jin

“…Thymic fatty replacement was evaluated using a four-point visual scoring scale (0–3). …”
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Phthalate metabolite mixtures and dose-response associations with depressive symptoms in U.S. adults by Penghui Li, Huimin Zhang, Yike Han, Shuo Xie, Wanning Li, Liyun Kong, Yue Zhang

“…Logistic regression, weighted quantile sum (WQS) regression, and quantile g-computation (QGC) models were employed to evaluate individual and mixture effects. …”
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Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study by Marie-Angélique Cazalis, Marie-Angélique Cazalis, Louis Kreitmann, Louis Kreitmann, Guillaume Monneret, Guillaume Monneret, Alexandre Pachot, Alexandre Pachot, Karen Brengel-Pesce, Karen Brengel-Pesce, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos

“…We combined CDK1, the hub gene of upregulated DEGs, and CX3CR1 and IL1b to compute expression ratios. The CDK1/CX3CR1 ratio had the best performance to predict all-cause ICU mortality, with an area under the ROC curve (AUROC) of 0.77 (95% confidence interval [CI] 0.88–0.66) at day 1 and of 0.82 (95% CI 0.91–0.72) at days 2–3 after ICU admission. …”
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Proteomic discovery analysis of quantitatively assessed emphysema in the general population. The MESA Lung Study by Daniel E. Guzman, Lisa Ruvuna, Claire J. Guo, Yifei Sun, Katherine A. Pratte, Ani W. Manichaikul, John S. Kim, Wendy S. Post, Alain G. Bertoni, Norrina B. Allen, Karol E. Watson, James S. Pankow, Eric A. Hoffman, Ruth F. Dubin, Rajat Deo, Igor Z. Barjaktarevic, Eugene R. Bleecker, Christopher B. Cooper, Victor E. Ortega, Annette T. Hastie, Robert Paine, James Michael Wells, Jeffrey L. Curtis, Edwin K. Silverman, Prescott G. Woodruff, Christine Kim Garcia, Jerome I. Rotter, Russell P. Bowler, Peter Ganz, R. Graham Barr

“…Objective We performed a proteomic discovery analysis of percent emphysema on computed tomography (CT) in a population-based, multiethnic sample from the Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study. …”
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Zinc Glycine supplementation improves bone quality in meat geese by modulating gut microbiota, SCFA's, and gut barrier function through Wnt10b/NF-κB axis by Zeshan Zulfiqar, Muhammad Arslan Asif, Mengqi Liu, Shuhang Zhang, Hamid reza Rafieian Naeini, Yalei Cui, Boshuai Liu, Yinghua Shi

“…The effects of different Zn sources on bone quality were evaluated in this study. A total of 300 one-d-old Wanpu mixed-sexed geese fed 2 basal diets added with best suited levels of 80 mg/kg inorganic zinc (ZnSO4), and 80 mg/kg Organic zinc (Zn-Glycine) for 60 d. …”
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Minimally Invasive Transthoracic Intramyocardial Cellular Transplantation Under Echocardiographic Guidance for Myocardial Impairment by Sulei Li, Bo Tao, Junsong Liu, Dongyue Liu, Yujia Wang, Jibin Zhang, Lei Tian, Baixuan Xu, Yan Fang, Yabin Wang, Xin Lou, Jinming Zhang, Feng Lan, Feng Cao, Hanjia Gao, Xiaoxia Fu

“…Cardiac function and morphology were evaluated by echocardiography. Results:. The operation time and postoperative recovery time of MI-TTEPIM group were significantly shorter than those of MI-SIM group ((28.3 ± 3.6) min vs. (97.0 ± 6.7) min, P < 0.001; (1.3 ± 0.3) d vs. (7.5 ± 0.9) d, P < 0.001). …”
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CBCT-based online adaptive radiotherapy of the bladder – geometrical and dosimetrical considerations compared to conventional IGRT by Jann Fischer, Laura Anna Fischer, Jona Bensberg, Natalia Bojko, Mohamed Bouabdallaoui, Jasper Frohn, Petra Hüttenrauch, Mandy Klingebiel, Daniela Schmitt, Katharina Tegeler, Daniela Wagner, Alina Wenzel, Jessica Moldauer, Niklas Christian Scheele, Hanne Elisabeth Ammon, Stephanie Bendrich, Sandra Donath, Leif Hendrik Dröge, Manuel Guhlich, Andrea Hille, Olga Knaus, Martin Leu, Jan Oelmann, Rami El Shafie, Georg Stamm, Arndt F. Schilling, Stefan Rieken

“…For each adaptive fraction (fx), three plans were evaluated: the scheduled plan (initial plan recalculated based on daily CBCT), the adapted plan (re-optimized to daily anatomy), and the verification plan (dose distribution recalculated on the verification CBCT - vCBCT). …”
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Age-stratified associations between radiotherapy and SPMs for FPHNC: a population-based cohort study by Yuan-Yuan Li, Qiong Liu, Si-Qi Ying, Xiu-Quan Wu, Xiao-Hui Zhang, Xiao-Mei Xie, Bing-Dong Sui, Yan Jin, Yang Jiao, Franklin R. Tay

“…Methods Using data from the Surveillance, Epidemiology, and End Results program (2004−2015), incidence rate ratios (IRRs) and standardized incidence ratios (SIRs) were evaluated for solid and hematologic SPMs associated with radiotherapy within different age groups. …”
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Risk factors for complete uterine rupture in patients with trial of labor after cesarean delivery by Hortense Didier‐Mathon, Gilles Kayem, Thibault Thubert, Loîc Sentilhes, Charles Garabedian, Thomas Schmitz, Diane Korb, Edouard Lecarpentier, François Goffinet, Cyril Raiffort, Marie‐Victoire Senat, Elie Azria, Aude Ricbourg, Alix Defline, Pierre Delorme

“…Logistic regression was used to compute crude odds ratios (ORs) and 95% confidence intervals (CIs) for uterine rupture. …”
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Cardiovascular magnetic resonance radiologic-pathologic correlation in radiomic analysis of myocardium in non-ischemic dilated cardiomyopathy by Amine Amyar, Shiro Nakamori, Long Ngo, Masaki Ishida, Satoshi Nakamura, Taku Omori, Keishi Moriwaki, Naoki Fujimoto, Kyoko Imanaka-Yoshida, Hajime Sakuma, Kaoru Dohi, Warren J. Manning, Reza Nezafat

“…Radiomic first-order and textural features were computed for each sequence from the mid-septal myocardium near the biopsy region. …”
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Exploring the Optoelectronic and Photovoltaic Characteristics of Lead‐Free Cs2TiBr6 Double Perovskite Solar Cells: A DFT and SCAPS‐1D Investigations by M. Khalid Hossain, Sahjahan Islam, M. Najmus Sakib, M. Shihab Uddin, Gazi F. I. Toki, Mirza H. K. Rubel, Jahanara Nasrin, Sara H. Shahatha, M. R. Mohammad, Asma A. Alothman, Chaitany Jayprakash Raorane, Rajesh Haldhar, Hichem Bencherif

“…Here, density functional theory (DFT) calculations are performed to examine the prospect of Cs2TiBr6 perovskite as a layer of absorber for photovoltaic cells (SCs). These computations looked at the material's structural, optical, and electrical characteristics. …”
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Improvements to the Met Office's global ocean–sea ice forecasting system including model and data assimilation changes by D. Mignac, J. Waters, D. J. Lea, M. J. Martin, J. While, A. T. Weaver, A. Vidard, C. Guiavarc'h, D. Storkey, D. Ford, E. W. Blockley, J. Baker, K. Haines, M. R. Price, M. J. Bell, R. Renshaw

“…This paper describes and evaluates the impacts of recent model and data assimilation (DA) updates on global FOAM when compared to its current operational version. …”
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Conservative treatment versus hip arthroscopy in patients with femoroacetabular impingement: a multilevel meta-analysis of randomized controlled trials by Nikolai Ramadanov, Jonathan Lettner, Maximilian Voss, Robert Hable, Robert Prill, Dobromir Dimitrov, Roland Becker

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Machine Learning Prediction Model of Waitlist Outcomes in Patients with Primary Sclerosing Cholangitis by Xun Zhao, MD, Maryam Naghibzadeh, MD, Yingji Sun, MSc, Arya Rahmani, BSc, Leslie Lilly, MD, Nazia Selzner, MD, PhD, Cynthia Tsien, MD, MPH, Elmar Jaeckel, MD, Mary Pressley Vyas, Rahul Krishnan, PhD, Gideon Hirschfield, MD, PhD, MB, Mamatha Bhat, MD, PhD

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Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches by Qihui Wu, Wei Wang, Zhuangzi Huang, Xianghao Lin, Maozhong Yao, Chuipu Cai, Guohu Weng, Yong Gu, Hongying Li, Jinman Liu, Jiansong Fang, Weirong Li

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A New Hyperparameter Tuning Framework for Regression Tasks in Deep Neural Network: Combined-Sampling Algorithm to Search the Optimized Hyperparameters by Nguyen Huu Tiep, Hae-Yong Jeong, Kyung-Doo Kim, Nguyen Xuan Mung, Nhu-Ngoc Dao, Hoai-Nam Tran, Van-Khanh Hoang, Nguyen Ngoc Anh, Mai The Vu

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Potential Protective Effect of Hepatitis B Immunity Against Diabetes Mellitus: A Retrospective Propensity-Matched Cohort Study by Nhu Quynh Phan, Shih-Jung Lin, Ngoc Hoang Le, Van Thuan Nguyen, Tan Ha Mai, Jin-Hua Chen, Min-Huei Hsu, Dinh Khanh Hoang, Phung Manh Thang, Ya-Li Huang, Chiehfeng Chen

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Prognostic factors in locally advanced oesophageal squamous cell carcinoma: a clinical and radiomic analysis of neoadjuvant immunochemotherapy before surgery by Yan Zhu, Zhenzhong Zhang, Shuangqing Chen, Genji Bai, Qingqing Xu, Lili Zhang, Max Gao, Aichao Ruan, Lili Guo

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