Targeting Biomarkers of Proliferation and Inflammation (Ki67, p53, and COX-2) in Actinic Keratoses with Photodynamic Therapy by Justyna Ceryn, Aleksandra Lesiak, Magdalena Ciążyńska, Dorota Sobolewska-Sztychny, Marcin Noweta, Olga Stasikowska-Kanicka, Karol Ciążyński, Iris Zalaudek, Joanna Narbutt

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Digitally delivered cognitive behavioral therapy for insomnia (CBT-I) for patients with chronic pain and insomnia (The Back2Sleep Trial): study protocol for a randomized controlled... by Maria Louise Stage Olsen, Jonas Bloch Thorlund, Robert Zachariae, Werner Vach, Laila Bendix, Julie Jespersen, Preben Kidmose, Christine Parsons, Kristian Kidholm, Henrik Bjarke Vægter

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Postoperative Harris Hip Score Versus Harris Hip Score Difference in Hip Replacement: What to Report? by Nikolai Ramadanov, Maximilian Voss, Robert Hable, Hassan Tarek Hakam, Robert Prill, Mikhail Salzmann, Dobromir Dimitrov, Roland Becker

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An Optimal Internet of Things-Driven Intelligent Decision-Making System for Real-Time Fishpond Water Quality Monitoring and Species Survival by Saima Kanwal, Muhammad Abdullah, Sahil Kumar, Saqib Arshad, Muhammad Shahroz, Dawei Zhang, Dileep Kumar

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Investigation of a Novel Noninvasive Risk Analytics Algorithm With Laboratory Central Venous Oxygen Saturation Measurements in Critically Ill Pediatric Patients by Sarah A. Teele, MD, MSHPEd, Avihu Z. Gazit, MD, Craig Futterman, MD, William G. La Cava, PhD, David S. Cooper, MD, MPH, MBA, Steven M. Schwartz, MD, MS, Joshua W. Salvin, MD, MPH

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Propofol orchestrates long non-coding RNAs in MCF7 cells, unraveling new avenues for breast cancer intervention by Cigir Biray Avci, Tuba Gokdogan Edgunlu, Tugba Suzek, Neslihan Pinar Ozates, Bakiye Goker Bagca, Aysegul Demirtas Bilgic, Cilem Ozdemir, Bakiye Ugur

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Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary... by Katrine Schultz Overgaard, Thomas Rueskov Andersen, Laurits Juhl Heinsen, Gokulan Pararajasingam, Roda Abdulkadir Mohamed, Freja Sønder Madsen, Irmelin Irene Aagaard Biesenbach, Kurt Højlund, Jess Lambrechtsen, Søren Auscher, Kenneth Egstrup

“…Abstract Background Pericoronary adipose tissue attenuation (PCATa), derived from coronary computed tomography angiography (CCTA), is a novel marker of inflammation in the coronary arteries. …”
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Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks by Hao Ye, Carlos Franco, Mostafa A. Aboouf, Markus Thiersch, Semih Sevim, Joaquin Llacer‐Wintle, Andrea Veciana, Gemma Llauradó‐Capdevila, Kaiyuan Wang, Xiang‐Zhong Chen, Qiao Tang, Roc Matheu, Pedro D. Wendel‐Garcia, Pedro A. Sánchez‐Murcia, Bradley J. Nelson, Cong Luo, Josep Puigmartí‐Luis, Salvador Pané

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Best evidence summary of the acute cardiac tamponade care practice (急性心包填塞护理实践的最佳证据总结) by CHEN Yizhu (陈一竹), XU Zhiying (许志英), JIA Xiaojing (贾晓静)

“…The quality of the selected literatures was evaluated by two researchers respectively, and the literatures meeting the criteria were included and the evidence was summarized. …”
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Trends of Female Breast Cancer Incidence, Mortality, and Survival in Fujian Province of China: 2011–2020 and Projection to 2025 by Yeying Wen, Jingyu Ma, Zhisheng Xiang, Yongtian Lin, Yongying Huang, Linying Liu, Yan Zhou, Yang Sun

“…Relative survival were computed as the ratio of observed survival to expected survival. …”
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Effective Extracellular Volume Fraction Determined by Equilibrium Contrast-Enhanced CT for Differentiating Autoimmune Pancreatitis from Pancreatic Ductal Adenocarcinoma by Akihiko Kanki, Yoshihiko Fukukura, Hidemitsu Sotozono, Kiyoka Maeba, Atsushi Higaki, Yuki Sato, Akira Yamamoto, Ryo Moriwake, Tsutomu Tamada

“…Diagnostic efficacy was evaluated through receiver operating characteristic (ROC) analyses. …”
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An interpretable machine learning model for predicting bone marrow invasion in patients with lymphoma via 18F-FDG PET/CT: a multicenter study by Xinyu Zhu, Denglu Lu, Yang Wu, Yanqi Lu, Liang He, Yanyun Deng, Xingyu Mu, Wei Fu

“…Additionally, a comparative diagnostic study evaluated reader performance with and without model assistance. …”
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective coh... by Damien Denimal, Maharajah Ponnaiah, Franck Phan, Anne-Caroline Jeannin, Alban Redheuil, Joe-Elie Salem, Samia Boussouar, Pauline Paulstephenraj, Suzanne Laroche, Chloé Amouyal, Agnès Hartemann, Fabienne Foufelle, Olivier Bourron

“…Methods The lower limb arterial calcification score (LLACS) was evaluated through computed tomography at baseline and after an average follow-up of 31.2 ± 3.7 months in a cohort of 150 patients with T2D. …”
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Medium and long-term aortic remodeling following aortic valve replacement combined with anticoagulation for DeBakey I aortic dissection by Yuanyuan Li, Shifeng Yang, Congshan Ji, Haoyuan Yang, Jinshu Sun, Juncheng Jiang, Ximing Wang, Long Wang

“…Seventy-two patients with preoperative and at least six months postoperative aortic computed tomography angiography images were included and stratified into a valve replacement group (n = 30) and a non-valve replacement group (n = 42). …”
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Closed circuit artificial ıntelligence model named morgaf for childhood onset systemic lupus erythematosus diagnosis by Emil Aliyev, Yagizhan Ugur, Veysel Cam, Yagmur Bayindir, Dilara Unal, Zeynep Balik, Seher Sener, Yelda Bilginer, Seza Ozen

“…Our study aims to develop a closed computer-based AI model to assist clinicians in diagnosis. …”
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Weight-adjusted-waist index: an innovative indicator of breast cancer hazard by Xinyi Huang, Hengzheng Cheng, Laifu Deng, Shuting Wang, Jiaxiu Li, An Qin, Chunqiang Chu, Wenyi Du, Xiao Liu

“…The waist circumference was divided by the square root of the body’s mass to compute WWI. Data were assessed via descriptive statistics to present data distributions according to BC grouping and WWI grouping, receiver operating characteristic curves (ROCs) to evaluate the obesity indicators’ applied value, logistic regression to reflect associations between WWI and BC prevalence, and restricted cubic splines (RCSs) and subgroup analysis forest plots to visualise and complement the relationships. …”
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Identifying Data-Driven Clinical Subgroups for Cervical Cancer Prevention With Machine Learning: Population-Based, External, and Diagnostic Validation Study by Zhen Lu, Binhua Dong, Hongning Cai, Tian Tian, Junfeng Wang, Leiwen Fu, Bingyi Wang, Weijie Zhang, Shaomei Lin, Xunyuan Tuo, Juntao Wang, Tianjie Yang, Xinxin Huang, Zheng Zheng, Huifeng Xue, Shuxia Xu, Siyang Liu, Pengming Sun, Huachun Zou

“…We trained a supervised machine learning model and developed pathways to classify individuals before evaluating its diagnostic validity and usability on an external cohort. …”
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Plasma glucose, HbA1c, insulin and lipid profile in Sudanese type 2 diabetic patients with cardiovascular disease: a case control study [version 2; peer review: 2 approved, 1 not a... by Rami Adam Humaida, Mariam Abbas Ibrahim, Ahmed Abd Alla, Nuha Eljailli Abubaker, Salsabbil Idris Abdallah

“…The purpose of this study is to evaluate the plasma levels of glucose, HbA1c, insulin, and lipid profile in Sudanese T2DM patients. …”
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Utilization of partograph and associated factors among obstetric caregivers in Ethiopia: a systematic review and meta-analysis by Mulat Ayele, Eyob Shitie Lake, Gizachew Yilak, Getinet Kumie, Biruk Beletew Abate, Alemu Birara Zemariam, Befkad Derese Tilahun

“…Cochrane I2 statistics were computed to assess heterogeneity among studies. A subgroup analysis was done based on the study region to minimize underlying heterogeneity. …”
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A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer by Hossein Khorramdelazad, Kowsar Bagherzadeh, Ali Rahimi, Ali Darehkordi, Alireza Najafi, Milad Karimi, Majid Khoshmirsafa, Gholamhossein Hassanshahi, Elaheh Safari, Reza Falak

“…Methods The molecular dynamic simulation method was employed to compute A1 binding affinity and energy for the CXCR4 receptor compared to AMD3100. …”
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