Effects of caloric restriction and exercise-induced weight loss on physiological dysregulation in postmenopausal women: The mediating role of fat mass and adipose tissue distributi... by Éloïse Routhier, Martin Brochu, Alan A. Cohen, Denis Prudhomme, Ahmed Ghachem

“…Total adipose tissue and its distribution were measured using dual-energy X-ray absorptiometry and computed tomography scan. DM was calculated using 7 blood biomarkers: total cholesterol, HDL-C, LDL-C, triglycerides, C-reactive protein, albumin, and ferritin. …”
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AI-assisted detection for chest X-rays (AID-CXR): a multi-reader multi-case study protocol by Fergus Gleeson, Alex Novak, Indrajeet Das, Ruchir Shah, Edwin van Beek, Sarim Ather, Howell Fu, Nabeeha Salik, Alan Campbell, Farhaan Khan, Abdala Trinidad Espinosa Morgado, Marusa Kotnik, Louise Wing, John Murchison, Jong Seok Ahn, Sang Hyup Lee, Ambika Seth

“…Advances in machine learning and computer vision technologies have led to the development of several artificial intelligence (AI) tools to detect abnormalities on CXRs, which may expand diagnostic support to a wider field of health professionals. …”
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Effects of canine movement on maxillary anterior en-masse retraction with clear aligners: a finite element study by Xin Yue Tang, Ting Jiang, Han Su, Daphne Yuchen Chin, Jia Yi Chen, Yu Qi Qin, Guo Hua Tang

“…Abstract Background In clear aligner therapy, tooth movement can be designed individually by computer software. However, the deformation of the aligner created by the virtual movement of one tooth may affect the actual movement of other teeth. …”
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Craniocaudal spread patterns of retropharyngeal lymph node metastasis in patients with hypopharyngeal carcinoma by Satomi Yoshimi, Ryo Toya, Mika Nakatake, Yoshiyuki Fukugawa, Hideki Ishimaru, Reiko Ideguchi, Hirofumi Koike, Yutaro Tasaki, Shinya Shiraishi, Yorihisa Orita, Toshinori Hirai, Natsuo Oya

“…Methods Two board-certified radiation oncologists evaluated the craniocaudal spread of RPLN metastases (RPLNMs) and the position of the hyoid bone using magnetic resonance images (diagnostic position) and RT-planning computed tomography simulator images (RT position with neck extension). …”
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Wen-Shen-Tong-Luo-Zhi-Tong Decoction alleviates bone loss in aged mice by suppressing LONP1-mediated macrophage senescence by Qinfeng Zhou, Kaixuan Wang, Cong Wang, Xiaoxian Sun, Lining Wang, Jie Sun, Yalan Pan, Muzhe Li, Zitong Zhao, Shijie Zhou, Qing Wang, Yafeng Zhang, Yong Ma, Yang Guo

“…However, the specific mechanisms by which WSTLZTD exerts its anti-SOP effects—particularly through modulating macrophage senescence—remain unclear.Objective The study aims to elucidate the role of WSTLZTD in macrophage senescence and SOP.Materials and methods Aged mice received low, medium, high-dose WSTLZTD. Bone loss was evaluated via micro-computed tomography, hematoxylin and eosin staining and osteocalcin, tartrate-resistant acid phosphatase marker analysis. …”
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Performance of lung cancer screening with low‐dose CT in Gejiu, Yunnan: A population‐based, screening cohort study by Meng‐Na Wei, Zheng Su, Jian‐Ning Wang, Maria J. Gonzalez Mendez, Xiao‐Yun Yu, Hao Liang, Qing‐Hua Zhou, Ya‐Guang Fan, You‐Lin Qiao

“…Background The performance of lung cancer screening with low‐dose computed tomography (CT) (LDCT) in China is uncertain. …”
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Discovery of Arylfuran and Carbohydrate Derivatives from the BraCoLi Library as Potential Zika Virus NS3^pro Inhibitors by Fernanda Kelly Marcelino e Oliveira, Beatriz Murta Rezende Moraes Ribeiro, Ellen Gonçalves de Oliveira, Marina Mol Sena Andrade Verzola, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Ricardo José Alves, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira, Jônatas Santos Abrahão, Mateus Sá Magalhães Serafim

“…Due to the lack of available therapeutics and few promising hit molecules, we computationally screened the well-described ZIKV protease (NS3^pro) as a drug target to revisit the small-molecule database Brazilian Compound Library (BraCoLi) and select potential inhibitors. …”
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Exploring therapeutic paradigm focusing on genes, proteins, and pathways to combat leprosy and tuberculosis: A network medicine and drug repurposing approach by Mohd Imran, Ahmed S. Alshrari, Mariah N. Hafiz, Mohammed M. Jawad, Abida Khan, Fadiyah Jadid Alanazi, Syed Mohammed Basheeruddin Asdaq

“…System biology networks revealed regulatory hub genes and molecular docking studies evaluated CHEMBL compounds as potential therapeutics. …”
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Fibrolamellar hepatocellular carcinoma: a case report and gene analysis by Akira Watanabe, Norifumi Harimoto, Hideyuki Saito, Reika Kawabata-Iwakawa, Takaomi Seki, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Kenichiro Araki, Hayato Ikota, Takashi Ishige, Koshi Mimori, Ken Shirabe

“…Case presentation A 14-year-old male patient underwent abdominal computed tomography (CT) to diagnose appendicitis, wherein a hepatic tumor was detected. …”
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Sleep hygiene and sleep quality among yoga and naturopathy medical students in India: a multisite cross-sectional study by Karishma Silwal, Prakash Babu Kodali, Hemanshu Sharma, Nair Dhiren Ajit, Abhay M. Shankaregowda, Renjish Mohanan, M. Jerin Subha, K. Vibhas, S. Sivaraman, Kinjal Bhalavat, V. R. Dhilip, Jyoti Nair, Vanitha Shetty, A. N. Vineetha, Dhanya U. M. Kumar, Rakesh Gupta, Ayswarya Rohini Pandian, Vakeel Khan, Pradeep M. K. Nair

“…Logistic regression models were employed to compute adjusted odds ratios (AORs) as measures of association.ResultsThe average SHI and PSQI scores were 22.49 (±6.34) and 6.52 (±3.01), respectively. …”
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Introducing the MESMER-M-TPv0.1.0 module: spatially explicit Earth system model emulation for monthly precipitation and temperature by S. Schöngart, S. Schöngart, L. Gudmundsson, M. Hauser, P. Pfleiderer, Q. Lejeune, S. Nath, S. I. Seneviratne, C.-F. Schleussner, C.-F. Schleussner, C.-F. Schleussner

“…For each ESM, we train on a single-ensemble member across scenarios and evaluate the emulator performance using simulations with historical and Shared Socioeconomic Pathways (SSP5-8.5) forcing. …”
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VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation by Zhihua Wang, Minghao Wang, Zhirong Luo, Yi Fu, Xiaomiao Zhu, Dongyu Li, Wenkai Jiang, Xiaogang Cheng, Chengxiong Cai, Xiaoru Zhu, Paul R. Cooper, Shengchao Wang, Wenxi He

“…Mineralization and transfection assays were conducted to evaluate the roles of histone deacetylase (HDAC)2 and HDAC5. …”
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Associations of three healthy dietary patterns with homeostatic dysregulation: results from the China Multi-Ethnic Cohort study by Hongmei Zhang, Quzong Deji, Ning Zhang, Yi Xiang, Yuan Zhang, Jiajie Cai, Tingting Yang, Jianzhong Yin, Yonglan Wei, Xianbin Ding, Xiong Xiao, Xing Zhao

“…Additionally, quantile G-computation was utilized to evaluate the relative contribution of each food group to the association with HD. …”
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Parenting in the Digital Age: A Scoping Review of Digital Early Childhood Parenting Interventions in Low- and Middle-Income Countries (LMIC) by Lena Jäggi, Lena Jäggi, Stella M. Hartinger, Stella M. Hartinger, Stella M. Hartinger, Günther Fink, Günther Fink, Dana C. McCoy, Milagros Alvarado Llatance, Milagros Alvarado Llatance, Kristen Hinckley, Kristen Hinckley, Kristen Hinckley, Lucero Ramirez-Varela, Leonel Aguilar, Andreana Castellanos, Daniel Mäusezahl, Daniel Mäusezahl, Daniel Mäusezahl

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Advanced and interpretable corneal staining assessment through fine grained knowledge distillation by Yuqing Deng, Pujin Cheng, Ruiwen Xu, Lirong Ling, Hongliang Xue, Shiyou Zhou, Yansong Huang, Junyan Lyu, Zhonghua Wang, Kenneth K. Y. Wong, Yimin Zhang, Kang Yu, Tingting Zhang, Xiaoqing Hu, Xiaoyi Li, Xiaoying Tang, Yan Lou, Jin Yuan

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Spectral Analysis of Light-Adapted Electroretinograms in Neurodevelopmental Disorders: Classification with Machine Learning by Paul A. Constable, Javier O. Pinzon-Arenas, Luis Roberto Mercado Diaz, Irene O. Lee, Fernando Marmolejo-Ramos, Lynne Loh, Aleksei Zhdanov, Mikhail Kulyabin, Marek Brabec, David H. Skuse, Dorothy A. Thompson, Hugo Posada-Quintero

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An AI explained systematic modular approach for enhanced Electricity Theft Detection for urbanized Smart Grid environment by Muhammad Ammar, Nadeem Javaid, Ali Arishi

“…In addition to its application on the state grid corporation of China dataset, we evaluate SATBlend on the Pakistan residential electricity consumption dataset, demonstrating its robustness and scalability across varied real-world datasets. …”
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Data-driven projections of candidate enhancer-activating SNPs in immune regulation by Markus Hoffmann, Tiago Vaz, Shreeti Chhatrala, Lothar Hennighausen

“…Results We developed a data-driven computational protocol to prioritize high-potential SNPs informed from former knowledge for experimental validation. …”
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Consistent microbial insights across sequencing methods in soil studies: the role of reference taxonomies by Niranjana Rose Edwin, Aoife Duff, Coline Deveautour, Fiona Brennan, Florence Abram, Orla O'Sullivan

“…Amplicon sequencing represents a cost-effective, less computationally demanding option, while shotgun sequencing provides deeper taxonomic resolution and access to the latest databases, making it suitable for detailed microbial profiling. …”
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Utilization of 3D printing modeling techniques in the simulation instruction of ultrasound-guided puncture procedures on scoliotic spines of spinal muscular atrophy by Di Xia, Fangliang Xing, Jiao Zhang, Jiaxin Lang, Gang Tan, Xulei Cui

“…Methods The 3D models of the scoliotic spines were developed from 3D reconstructions of high-resolution, computed tomography images from patients with spinal scoliosis, while the models of the skin to the bone structure were constructed based on the 3D reconstructions of the skin contours. …”
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