Non-coding repeat analyses in patients with Parkinson’s disease by Makito Hirano, Makoto Samukawa, Satoko Miyatake, Satoko Miyatake, Yuko Yamagishi, Chiharu Isono, Rino Yoshikawa, Kazumasa Saigoh, Atsushi Terayama, Yuji Higashimoto, Eriko Koshimizu, Takeshi Mizuguchi, Kanako Fujii, Yoshiyuki Mitsui, Naomichi Matsumoto, Naomichi Matsumoto, Naomichi Matsumoto, Yoshitaka Nagai

“…Functional imaging, such as dopamine-transporter single photon emission computed tomography, showed abnormal findings in patients with non-coding repeat expansions.DiscussionOur findings revealed the importance of non-coding repeat expansions in Japanese patients with PD. …”
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Characteristics and Treatment Trends for Emphysematous Pyelonephritis in Korea: A 10-Year Multicenter Retrospective Study by Seung-Kwon Choi, Koo Han Yoo, Jeong Woo Lee, Seung Il Jung, Eu Chang Hwang, Joongwon Choi, Woong Bin Kim, Jung Sik Huh, Jin Bong Choi, Yeonjoo Kim, Jae Min Chung, Ju-Hyun Shin, Jae Hung Jung, Hong Chung, Sangrak Bae, Tae-Hyoung Kim

“…Materials and Methods Two hundred and seventeen patients diagnosed with EPN were evaluated using abdominal computed tomography in 2011-2021 at 15 institutes in Korea. …”
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A Two‐Step Risk Score for Prediction of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation by Alexandra Janiszewski, Julia Lueg, Daniel Schulze, Benjamin Juri, Louis Morell, Maria Hajduczenia, Pierre Hennig, Aslihan Erbay, Alexander Lembcke, Stefan Niehues, Ulf Landmesser, Karl Stangl, David Leistner, Verena Tscholl, Henryk Dreger

“…Methods and Results Between January 2019 and December 2020, 1039 patients underwent TAVI at our institution. We retrospectively evaluated clinical, electrocardiographic, echocardiographic, computed tomographic, and periprocedural data. …”
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Development and validation of a CT-based multi-omics nomogram for predicting hospital discharge outcomes following mechanical thrombectomy by Feifan Liu, Jiayi Hong, Yuhan Chen, Huan Liu, Yue Wang, Lijian Su, Sheng Hu, Jingjing Fu

“…ObjectiveThis study aimed to develop a multi-omics nomogram that combines clinical parameters, radiomics, and deep transfer learning (DTL) features of hyperattenuated imaging markers (HIM) from computed tomography scans immediately following mechanical thrombectomy (MT) to predict functional outcomes at discharge.MethodsThis study enrolled 246 patients with HIM who underwent MT. …”
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68Ga-PSMA PET/CT versus CT and bone scan for investigation of PSA failure post radical prostatectomy by Yuigi Yuminaga, Chris Rothe, Jonathan Kam, Kieran Beattie, Mohan Arianayagam, Chuong Bui, Bertram Canagasingham, Richard Ferguson, Mohamed Khadra, Raymond Ko, Ken Le, Diep Nguyen, Celi Varol, Matthew Winter

“…Objective: To evaluate the use of Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA PET/CT), compared with conventional CT abdomen/pelvis (CTAP) and whole body single photon emission CT bone scan (BS), for detection of local or distant metastasis following biochemical failure/recurrence in post-prostatectomy patients. …”
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Pharmacological targeting of ferroptosis in hypoxia-induced pulmonary edema: therapeutic potential of ginsenoside Rg3 through activation of the PI3K/AKT pathway by Yacong He, Yilang Wang, Huxinyue Duan, Demei Huang, Nan Jia, Zherui Shen, Zhenxing Wang, Mingjie Wang, Tianzhu Zhao

“…Western blotting, network pharmacology and computational simulations were utilized to identify molecular targets of G-Rg3. …”
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Blood eosinophil count correlates with alveolar damage in emphysema-predominant COPD by Saya Nakamura, Keiko Wakahara, Suguru Majima, Eito Yokoi, Eriko Fukutani, Ryo Otsuki, Shingo Iwano, Toyofumi Fengshi Chen-Yoshikawa, Fumie Kinoshita, Takashi Abe, Toyokazu Sashio, Tomoki Kimura, Kenji Izuhara, Naozumi Hashimoto, Makoto Ishii, Yoshinori Hasegawa

“…Blood eosinophil count, serum IgE level, serum periostin level, and chest computed tomography (CT) scans were evaluated. Eosinophilic COPD was defined as COPD with a blood eosinophil count ≧ 300/µL. …”
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Establishing an intraoperative, mobile CBCT-based workflow for gynecologic brachytherapy: primary experience and benefit assessment by Andre Karius, Andre Karius, Vratislav Strnad, Vratislav Strnad, Christoph Bert, Christoph Bert, Rainer Fietkau, Rainer Fietkau, Ricarda Merten, Ricarda Merten, Claudia Schweizer, Claudia Schweizer

“…Dosimetric effects were evaluated by calculating common dose–volume parameters for target volume and organs at risk (OARs) and comparing them in both a previous patient cohort and scenarios simulating sole ultrasound guidance. …”
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Dietary intake and quality for young adolescents in sub‐Saharan Africa: Status and influencing factors by Isabel Madzorera, Sabri Bromage, Mary Mwanyika‐Sando, Alain Vandormael, Huda Sherfi, Amare Worku, Sachin Shinde, Ramadhani Abdallah Noor, Till Baernighausen, Deepika Sharma, Wafaie W. Fawzi

“…Dietary intake was assessed using food frequency questionnaires, and diet quality computed using the Global Diet Quality Score (GDQS). …”
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Association between per- and polyfluoroalkyl substances exposure and blood pressure: From epidemiological evidence to mechanistic insights by Ziwen An, Yayuan Mei, Zhenzhen Tan, Zexuan Jiang, Xiuli Zeng, Longfei Li, Zheyuan Liu, Haiyan Shi, Jing Li, Wenjing Duan, Yiming Zhu, Mingmei Guo, Yi Liu, Ang Li, Huicai Guo

“…We employed multiple linear regression and quantile g-computation models to examine the effects of plasma PFASs on systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP). …”
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Artificial neural network-based forecasting of air temperature reduction in a tube bank under electric field by Ekuong Tang, Attakorn Asanakham, Thoranis Deethayat, Tanongkiat Kiatsiriroat

“…The heat transfer rate and outlet air temperature were the output results. The study evaluated the optimal ANN model structure, including the appropriate number of neurons in the hidden layer, the number of epochs, and the suitable activation function for predicting heat transfer performance under an electric field. …”
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Stereotactic body radiotherapy: a new non-invasive way to conduct pulmonary artery denervation by Manzhen Liao, Manzhen Liao, Taoyue Yao, Yonghui Xie, Shelby Kutty, Jinqiao Liu, Wei Peng, Wei Peng, Ting Huang, Huaiyang Chen, Huaiyang Chen, Haoqin Fan, Zhenghui Xiao, Qiming Liu, Yunbin Xiao

“…Pulmonary artery sympathetic nerves were evaluated by pathological staining.ResultsThe SBRT procedure was successfully performed in all six rabbits. …”
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Regression-based leaf nitrogen concentration estimation of young Cephalotaxus hainanensis in small and imbalanced samples by Mengmeng Shi, Tian Wang, Ling Lin, Qingxue Li, Zhulin Chen, Xingjing Chen, Peng Wang, Xuefeng Wang

“…This study used a non-destructive method that combines computer vision and machine learning to estimate the LNC in Cephalotaxus hainanensis, an endangered tree species. …”
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Detection and In Vivo Validation of <i>Dichorhavirus</i> e-Probes in Meta-Transcriptomic Data via Microbe Finder (MiFi^®) Discovers a Novel Host and a Possible New Strain... by Avijit Roy, Jonathan Shao, Andres S. Espindola, Daniel Ramos Lopez, Gabriel Otero-Colina, Yazmín Rivera, Vessela A. Mavrodieva, Mark K. Nakhla, William L. Schneider, Kitty Cardwell

“…The E-probe Diagnostic for Nucleic Acid Analysis (EDNA) was developed to reduce computational effort and then integrated within Microbe-Finder (MiFi^®) online platform to design and evaluate e-probes in raw High Throughput Sequencing (HTS) data. …”
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Efficacy of Lycium barbarum (Goji berry) mouthwash for managing periodontitis: a randomized clinical trial [version 4; peer review: 2 approved, 1 approved with reservations] by Laasya Shettigar, Aditi Chopra, Richard Lobo, Amee Sanghavi, Shobha Ullas Kamath, Prajna P Nayak, Ashmeet Shah, Usha Y Nayak, Mangalore Shravya S, Padmaja A Shenoy, ShivaPrasada Gadag

“…Hence the present study aims to evaluate the efficacy of goji berry mouthwash compared to chlorhexidine mouthwash for managing periodontitis. …”
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Impact of Distal Tibiofibular Joint Anatomy on Reduction Outcome in Dynamic Suture Button Stabilization of the Distal Syndesmosis—A CT Analysis by Robert Hennings, Carolin Fuchs, Firas Souleiman, Henkelmann Jeanette, Ullrich Joseph Spiegl, Christian Kleber, Annette B. Ahrberg-Spiegl

“…<b>Materials and Methods:</b> Forty-four (21 females, 23 males) consecutive postoperative bilateral computed tomography scans after stabilization of the DTFJ by SBS in the course of operative treatment of unstable ankle fractures were retrospectively analyzed. …”
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Selection and validation of reference genes for quantitative real-time PCR during the developmental stages of seeds in Sophora davidii by Jingjing Li, Jingjing Li, Shanrong Han, Shanrong Han, Zongren Xu, Bin Deng, Na Zheng, Na Zheng, Yaqiong Su, Yaqiong Su, Ziyao Qiao, Ziyao Qiao, Yun Yang, Yun Yang, Hong Zhang, Zongsuo Liang, Jing Liu, Shuai Liu

“…Five computational tools—GeNorm, NormFinder, BestKeeper, ΔCt, and RefFinder—were employed to comprehensively analyze the stability of these genes.ResultsAmong the candidate genes, EF1G and RL291 exhibited the highest expression stability, whereas RL182 proved unsuitable as a reference gene. …”
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Ascending Aortic Calcification as a Potential Predictor for Low Bone Mineral Density: A Pilot Study by Hirofumi Bekki, Takeshi Arizono, Yuki Suzuki, Akihiko Inokuchi, Takahiro Hamada, Ryuta Imamura, Ryunosuke Oyama, Yuki Hyodo, Eiji Kinoshita, Takumi Kita

“…Method. Plain film and computed tomography (CT) images of the thorax were obtained from 91 patients with hip fractures. …”
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Rising Threat: Long‐Term Trends in the Incidence and Mortality of Thymic Epithelial Tumor by Zishan Chen, Shiwen Liu, Chunting Chen, Jinmang Zhuang, Xinying Xu, Maolin Liu, Fancai Lai, Fei He

“…Conclusions The incidence and mortality of TETs have steadily increased over time, and these trends might be related to the widespread use of computed tomography for lung cancer screening and the increasing number of TETs found incidentally. …”
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Specific bone region localization of osteolytic versus osteoblastic lesions in a patient-derived xenograft model of bone metastatic prostate cancer by Takeshi Hirata, Seung Chol Park, Michelle T. Muldong, Christina N. Wu, Tomonori Yamaguchi, Amy Strasner, Omer Raheem, Hiromi Kumon, Robert L. Sah, Nicholas A. Cacalano, Catriona H.M. Jamieson, Christopher J. Kane, Koichi Masuda, Anna A. Kulidjian, Christina A.M. Jamieson

“…Methods: Quantitative micro-computed tomography (micro-CT) and histological analyses were performed to evaluate the effects of direct injection of PCSD1 cells or media alone (Control) into the right femurs of Rag2−/−γc−/− male mice. …”
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