Novel Approach Methodologies in Modeling Complex Bioaerosol Exposure in Asthma and Allergic Rhinitis Under Climate Change by Esra Atalay-Sahar, Ece Yildiz-Ozturk, Su Ozgur, Arzu Aral, Emre Dayanc, Tuncay Goksel, Ralph Meuwissen, Ozlem Yesil-Celiktas, Ozlem Goksel

“…This review critically evaluates the potential of NAMs in researching airway diseases, with a focus on allergy and asthma. …”
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An imaging and genetic-based deep learning network for Alzheimer's disease diagnosis by Yuhan Li, Donghao Niu, Keying Qi, Dong Liang, Dong Liang, Xiaojing Long, Xiaojing Long

“…Conventional computer-aided diagnostic techniques for Alzheimer's disease (AD) predominantly rely on magnetic resonance imaging (MRI) in isolation. …”
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Analysis of Respiratory System Functional Parameters at Different Time Points after COVID-19 by O. I. Savushkina, E. S. Muravieva, S. N. Avdeev, I. Ts. Kulagina, M. M. Malashenko, A. A. Zaytsev

“…The objective: to define the type and evaluate the severity of respiratory functional disorders after COVID-19. …”
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Deep learning surrogate models for spatiotemporal prediction of coastal flooding inundations in Tianjin, China by Wanchao Bian, Jiayi Fang, Pin Wang, Qinke Sun, Jian Fang, Feng Kong, Tangao Hu

“…Four models—U-Net, CNN-LSTM, ConvLSTM, and CNN-Transformer—were developed and evaluated. The training dataset was generated using the LISFLOOD-FP hydrodynamic model under extreme sea-level scenarios. …”
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The Thermal Comfort Performance in an Indonesian Refugee Tent: Existing Conditions and Redesigns by Muhammad Haiqal, Laina Hilma Sari, Husni Husin, Akhyar Akhyar, Abdul Munir, Kamila Bilqis

“…Ensuring thermal comfort in these shelters is crucial for the well-being and recovery of displaced individuals. This study evaluates the thermal comfort of refugee tents deployed in Aceh through a combination of field measurements and computational simulations using Ansys Fluent 19.2 (CFD software). …”
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Joining forces for pathology diagnostics with AI assistance: The EMPAIA initiative by Norman Zerbe, Lars Ole Schwen, Christian Geißler, Katja Wiesemann, Tom Bisson, Peter Boor, Rita Carvalho, Michael Franz, Christoph Jansen, Tim-Rasmus Kiehl, Björn Lindequist, Nora Charlotte Pohlan, Sarah Schmell, Klaus Strohmenger, Falk Zakrzewski, Markus Plass, Michael Takla, Tobias Küster, André Homeyer, Peter Hufnagl

“…We prioritized requirements and evaluated the use of AI in real clinical settings with 14 different pathology laboratories in Europe and Asia. …”
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RAMAS-Net: a module-optimized convolutional network model for aortic valve stenosis recognition in echocardiography by Yejia Gan, Wanzhong Huang, Yan Deng, Xiaoying Xie, Yuanyuan Gu, Yaozhuang Zhou, Qian Zhang, Maosheng Zhang, Yangchun Liu

“…The model enhanced the ResNet50 backbone by replacing Stage 4 with Spatial and Channel Reconstruction Convolution (SCConv) and Multi-Dconv Head Transposed Attention (MDTA) modules, aiming to reduce redundant computations and improve feature extraction capabilities.ResultsThe proposed method was evaluated on the TMED-2 echocardiography dataset, achieving an accuracy of 94.67%, an F1-score of 94.37%, and an AUC of 0.95 for AS identification. …”
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An integrated graph-spatial method for high-performance geospatial-temporal semantic query by Zichen Yue, Wei Zhu, Xin Mei, Shaobo Zhong

“…We implemented a GraST prototype system by integrating PostGIS and Neo4j, and conducted performance evaluations and case studies on large-scale real-world datasets. …”
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Repurposing piroxicam enhances the antineoplastic effects of docetaxel and enzalutamide in prostate cancer cells using 2D and 3D in vitro culture models by Amani Yehya, Fatima Ghamlouche, Raed Karami, Sana Hachem, Zahraa Salhab, Yen-Nien Liu, Georges Daoud, Wassim Abou-Kheir

“…Non-steroidal anti-inflammatory drugs (NSAIDs), widely used for treating inflammation, are being explored for their potential efficacy in cancer treatment, including prostate cancer (PCa). This study aims to evaluate the efficacy of Piroxicam (PXM), an NSAID, in enhancing the sensitivity of PCa cells to chemotherapy and hormonal drugs.MethodsComputational analysis was conducted to identify differentially expressed genes between our established murine PCa cell models, PLum-AD (androgen-dependent) and PLum-AI (androgen-independent), to uncover potential therapeutic targets. …”
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Life Cycle Assessment in the Early Design Phase of Buildings: Strategies, Tools, and Future Directions by Deepak Kumar, Kranti Kumar Maurya, Shailendra K. Mandal, Basit A. Mir, Anissa Nurdiawati, Sami G. Al-Ghamdi

“…Life Cycle Assessment (LCA) has emerged as a key methodology for evaluating environmental impacts throughout a building’s life cycle, yet its integration in the early design phase remains limited. …”
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Integrating CT radiomics and clinical data with machine learning to predict fibrosis progression in coalworker pneumoconiosis by Xiaobing Li, Xiaobing Li, Xiaobing Li, Xiaobing Li, Xiaobing Li, Qian Li, Qian Li, Qian Li, Qian Li, Xinyi Xie, Wei Wang, Xuemei Li, Tingqiang Zhang, Tingqiang Zhang, Tingqiang Zhang, Tingqiang Zhang, Li Zhang, Li Zhang, Li Zhang, Li Zhang, Yongsheng Liu, Yongsheng Liu, Yongsheng Liu, Yongsheng Liu, Li Wang, Li Wang, Li Wang, Li Wang, Wutao Xie

“…The performance of these models was evaluated in the test cohort using receiver operating characteristic (ROC) curves and decision curve analysis (DCA).ResultsIn the training cohort, the area under the curve (AUC) for the clinical, radiomics, and joint models were 0.835, 0.879, and 0.945, respectively. …”
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Comparison of Superovulated Embryo Quality in Simmental Cattle Inseminated with 0 °C-Refrigerated and Liquid Nitrogen-Frozen Semen by Jie-Ru Wang, Fei Huang, Peng Niu, Hong Cheng, Hui-Min Qu, Xiao-Peng Li, Xue-Yan Wang, Jie Wang, Jia-Jia Suo, Di Fang, Qing-Hua Gao

“…Semen collected from five bulls was equally divided into two groups: one diluted with a 0 °C refrigeration solution and stored at 0 °C, and the other diluted with a cryopreservation solution and stored in liquid nitrogen for 24 h. We evaluated sperm motility, progressive motility (assessed via a computer-assisted sperm analyzer), acrosome integrity, and plasma membrane integrity in both groups. …”
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A Rational Design Method for the Nagoya Type-III Antenna by Daniele Iannarelli, Francesco Napoli, Antonella Ingenito, Alessandro Cardinali, Antonella De Ninno, Simone Mannori

“…Considering previous studies on helicon waves theory, we compare three different design methods, each based on simplifying different modelling assumptions, and evaluate the predictions of these models with results from full-wave 3D simulations. …”
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Development and validation of a multi-omics hemorrhagic transformation model based on hyperattenuated imaging markers following mechanical thrombectomy by Lina Jiang, Guoping Zhu, Yue Wang, Jiayi Hong, Jingjing Fu, Jibo Hu, Shengxiang Xiao, Jiayi Chu, Sheng Hu, Wenbo Xiao

“…Model performance was evaluated using metrics such as accuracy, sensitivity, specificity, receiver operating characteristic curves, and area under curve (AUC). …”
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Prognostic impact of extracellular volume fraction derived from equilibrium contrast-enhanced CT in HCC patients receiving immune checkpoint inhibitors by Xiaona Fu, Yusheng Guo, Kailu Zhang, Zhixuan Cheng, Chanyuan Liu, Yi Ren, Lianwei Miao, Weiwei Liu, Shanshan Jiang, Chen Zhou, Yangbo Su, Lian Yang

“…Abstract This study aimed to investigate whether extracellular volume (ECV) fraction derived from equilibration contrast-enhanced computed tomography (CECT) affects prognosis in HCC patients receiving ICIs. …”
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A guideline study for optimal machine learning approaches to predict the off-design performance of sCO2-PCHEs by Xin Sui, Wenqi Wang, Chunyang Liu, Peixin Dong

“…Then, the sensitivity of ML models to hyperparameter, split ratio, and data distribution is evaluated. Finally, a mutual assessment is conducted to rank their accuracy and generalization when predicting the heat transfer coefficient across three real-world operating scenarios. …”
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Effect of brown adipose tissue activation on myocardial fluorine-18-fluorodeoxyglucose uptake by Saud A. Alenezi, Shorouk F. Dannoon, Naheel S. Alnafisi, Saqr M. Asa'ad, Medhat M. Osman, Abdelhamid H. Elgazzar

“…The scans were retrospectively reviewed by two nuclear medicine physicians who visually evaluated the intensity of myocardial [18F] FDG uptake. …”
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Exploring dihydropyrimidone derivatives as modulators of carbohydrate catabolic enzyme to mitigate diabetes by Syed Parween Ali, Farheen Mansoor, Shaymaa Fadhel Abbas Albaayit, Farman Ali, Ayed A. Dera, Muhammad Shahbaz, Jawad Ullah, Hailah M. Almohaimeed, Reem M. Gahtani, Ahmed M. Abdulfattah, Fahad M. Alshabrmi, Sarfaraz Alam, Saeed Ullah

“…Dihydropyrimidones, a core structural class present in various biologically active natural compounds, have been recognized for their diverse therapeutic potential, including anti-diabetic properties. In this study, we evaluated a library of previously synthesized 37 Dihydropyrimidone derivatives to assess their potential as α-glucosidase inhibitors. …”
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Radiation-induced changes of reactive astrocyte distribution in mice as a late response to partial-brain proton irradiation by Robin Hegering, Sindi Nexhipi, Theresa Suckert, Johannes Soltwedel, Elke Beyreuther, Mechthild Krause, Antje Dietrich, Armin Lühr

“…Dose distributions were simulated on pre-irradiation cone-beam computed tomography and co-registered to the histological slices. …”
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Planned Y-shaped Muscle Wrapping for Salvaging Aortic Graft Infection: Latissimus Dorsi and Reverse Serratus Anterior Muscles by Itaru Tsuge, MD, PhD, Susumu Saito, MD, PhD, Kazuhiro Takatoku, MD, Takehiko Matsuo, MD, PhD, Kenji Minatoya, MD, PhD, Naoki Morimoto, MD, PhD

“…Postoperative computed tomography and the clinical course indicated successful regulation of infection. …”
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