DTI-RME: a robust and multi-kernel ensemble approach for drug-target interaction prediction by Yuqing Qian, Xin Zhang, Yizheng Wang, Quan Zou, Chen Cao, Yijie Ding, Xiaoyi Guo

“…Abstract Background Drug-target interaction (DTI) refers to the specific mechanisms by which drug molecules interact with biological targets within a biological system. Computational methods are widely employed for DTI prediction, as they are time-efficient and resource-saving compared to experimental approaches. …”
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A CT-based machine learning model for using clinical-radiomics to predict malignant cerebral edema after stroke: a two-center study by Lingfeng Zhang, Gang Xie, Yue Zhang, Yue Zhang, Junlin Li, Junlin Li, Wuli Tang, Wuli Tang, Ling Yang, Ling Yang, Kang Li

“…PurposeThis research aimed to create a machine learning model for clinical-radiomics that utilizes unenhanced computed tomography images to assess the likelihood of malignant cerebral edema (MCE) in individuals suffering from acute ischemic stroke (AIS).MethodsThe research included 179 consecutive patients with AIS from two different hospitals. …”
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Feasibility and Safety of Bedside Percutaneous Catheter Drainage of Necrotic Pancreatic Fluid Collections in the Intensive Care Unit by Pankaj Gupta, Shreya Sehgal, Jyoti Gupta, Jayanta Samanta, Harshal Mandavdhare, Vishal Sharma, Usha Dutta, Rakesh Kochhar, Manavjit Singh Sandhu

“…The management of pancreatic fluid collections (PFCs) in this group is challenging. We aimed to evaluate the feasibility and safety of bedside percutaneous ultrasound (USG)-guided interventions in necrotic PFC in ICU patients. …”
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Quinoline Quest: Kynurenic Acid Strategies for Next-Generation Therapeutics via Rational Drug Design by Masaru Tanaka, István Szatmári, László Vécsei

“…Thus, contemporary research highlights halogenation, esterification, and computational modeling to enhance structure–activity relationships. …”
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A Modified Kalman Filter Based on Radial Basis Function Neural Networks for the Improvement of Numerical Weather Prediction Models by Athanasios Donas, George Galanis, Ioannis Pytharoulis, Ioannis Th. Famelis

“…This self-adaptive computational system enables the simultaneous targeting of the systematic and the remaining non-systematic parts of the forecast error, producing an innovative and efficient post-process strategy. …”
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Design of a multi-epitope vaccine candidate against Helicobacter pylori in gastric cancer: an immunoinformatic approach by Shojaeian, Ali, Sanami, Samira, Mahmoudvand, Shahab, Amini, Razieh, Alibakhshi, Abbas

“…The complexity of such a bacterium has made it difficult to develop an effective treatment. Thus, a computational approach to developing antigenicity, stability, and safety in vaccines against this pathogen will aid in the management of related diseases. …”
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AI-Driven Mapping System for Smart Parking Management Applications Using an INS-GNSS-Solid-State LiDAR-Monocular Camera Fusion Engine Empowered by HD Maps by Kai-Wei Chiang, Syun Tsai, Jou-An Chen, Surachet Srinara, Meng-Lun Tsai, Chih-Yun Hsieh, Jyun-Yang Hung, Chalermchon Satirapod, Naser El-Sheimy

“…The goal was to achieve high accuracy with minimal computational resources and infrastructure costs. The proposed system’s performance for dynamic HD map object updating was evaluated through parking management tests. …”
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The Application of Artificial Intelligence in Medical Diagnostics: Implications for Sports Medicine by Michał Bolek, Dominika Musialska, Aleksandra Kędzia, Bartosz Jagieła, Monika Fidyk, Magda Minkiewicz, Maciej Dyda

“…These AI-driven tools can predict injury risks by evaluating training loads, biomechanics, and real-time physiological signals. …”
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Spectrum Fitting Approach for Passive Wireless SAW Sensor Interrogation Using Software-Defined Radio by Shihao Wang, Qi Wang, Guopeng Zhu, Lei Liu, Xinning Cao, Tingxin Ren, Yue Zhou, Hao Jin

“…However, conventional frequency estimation methods often rely on iterative algorithms with high computational complexity, limiting their real-time applicability. …”
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Rapid assessment of seismic performance for multi-story RC frame buildings using direct prediction method by Xin Chen, Haojie Hu, Wenwei Fu, Tao Liu, Yong Sun, Cong Liu

“…Traditional methods for seismic performance calculation are usually based on refined finite element models, resulting in low computational efficiency. In this paper, a direct prediction method for rapid assessment of the seismic performance for multi-story reinforcement concrete (RC) frame buildings is proposed. …”
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Arterial Anastomosis to Injured Vessels: Outcomes in Lower Extremity Trauma Reconstruction by Ellen Wang, BS, Jessica R. Nye, BS, Imran Rizvi, MD, Kylie R. Swiekatowski, BA, Bora Kahramangil, MD, Paul Won, MD, Noa G. Kopplin, BS, Stephen F. Parlamas, BS, Jeffrey G. Trost, MD, Mohin A. Bhadkamkar, MD

“…Although traditional teaching advocates that microsurgical anastomoses should be performed to uninjured vessels outside the zone of injury (ZOI), there is no defined way to assess the extent of the ZOI, and uninjured vessels may not be available. To evaluate the complications ascribed to the ZOI and injured vessels, outcomes between arterial anastomoses fashioned from within the ZOI versus noninjured recipient vessels were compared. …”
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DNA Binding with Dipyrromethene Ruthenium(II) Complexes by Maria Isabel Murillo, Carlos Felipe Mejia, Andrés Restrepo-Acevedo, Benjamin Barraud, Adrian L. Orjuela, Marcos Flores-Alamo, Rubén A. Toscano, Jorge Alí-Torres, Alexander D. Ryabov, Ronan Le Lagadec

“…The DNA-binding ability of the <b>Ru-3</b>–<b>Ru-6</b> complexes was evaluated by UV–vis DNA titration. Compound <b>Ru-3</b> exhibited the highest binding energy, outperforming the complexes containing a dipyrrin ligand substituted by chlorides (<b>Ru-4</b> and <b>Ru-5</b>) or a <i>meso</i>-substituted dipyrrin (<b>Ru-6</b>). …”
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Assessment of concrete-to-concrete shear bond behavior using 3-D direct shear testing by Mohamad Ezzedine El Dandachy, Dalia AlMohamad, Matthieu Briffaut, Abdulkader El-Mir, Joseph J. Assaad, Hilal El-Hassan

“…The substrate post-hardening surface morphology was evaluated using a high-resolution laser profilometer. …”
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Investigating the role of non-synonymous variant D67N of ADGRE2 in chronic myeloid leukemia by Ayesha Afzal, Harooma Jamshaid, Yasmin Badshah, Maria Shabbir, Janeen H. Trembley, Sameen Zafar, Ghulam Murtaza Kamal, Tayyaba Afsar, Fohad Mabood Husain, Suhail Razak

“…Methods Non-synonymous SNPs of ADGRE2 were retrieved from the ENSEMBL, COSMIC, and gnomAD genome browsers, and the pathogenicity of deleterious variants was assessed using several established computational tools, including SIFT, CADD, REVEL, PolyPhen, and MetaLR. …”
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Case Report: Pulmonary sclerosing pneumocytoma mimicking as a neuroendocrine tumor on 18F-FDG and 68Ga-DOTATATE PET/CT: a case presentation by Ronghua Yu, Ronghua Yu, Wei Zhao, Yonglin Yu, Xianwen Hu

“…She underwent a chest computed tomography (CT) scan which revealed a circular soft tissue density shadow in the upper lobe of the left lung. …”
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Variance and covariance components of agronomic and quality traits assessed in tetraploid potato and their implications on practical breeding by Kathrin Thelen, Kathrin Thelen, Vanessa Prigge, Anja Kohlmorgen, Katja Muders, Bernd Truberg, Stefanie Hartje, Juliane Renner, Benjamin Stich, Benjamin Stich

“…Model calculations and computer simulations can be used to optimize the resource allocation in potato breeding programs but require quantitative genetic parameters. …”
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Risk Assessment by a New FMEA Model based on an Extended AHP Method under a Fuzzy Environment by Reza Fattahi, Reza Tavakkoli-Moghaddam, Mohammad Khalilzadeh, Nasser Shahsavari-Pour, Roya Soltani

“…In this study, a new fuzzy analytic hierarchy process (AHP)-based FMEA model is introduced for evaluating the risks of various failure modes more precisely. …”
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Design optimization of Bakelite support for LNG ISO tank 40 ft using finite element analysis by Tuswan Tuswan, Taufiq Rafif Naufal, Mursid Ocid, Sari Dian Purnama, Rizal Nandiko, Yuniati Yuniati, Sasmito Agus, Machfudin Andik, Sandjaja Irfan Eko, Utina Muhammad Ridwan, Harmadi Rudias, Muttaqie Teguh

“…To ensure structural integrity and regulatory compliance, the resulting designs are evaluated under the ISO 1496 standard loading scenarios, including lifting, stacking, and racking. …”
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GeoDGP: One‐Hour Ahead Global Probabilistic Geomagnetic Perturbation Forecasting Using Deep Gaussian Process by Hongfan Chen, Gabor Toth, Yang Chen, Shasha Zou, Zhenguang Huang, Xun Huan

“…The current operational first‐principles Michigan Geospace model provides effective forecasts of dBH, but requires significant computational resources to achieve real‐time speeds. …”
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Enhanced heat transfer in parabolic trough using novel perforated plus-shaped turbulator by Attia Boudjemline, Ali B.M. Ali, S.A.M. Mehryan, A.I. Ismail, Ibrahim Mahariq, Nidhal Ben Khedher

“…Two PSTT configurations—simple and perforated—are evaluated, with variations in pitch lengths (160–20 mm), clearances (0.75–0.05 mm), and hole diameters (1–5 mm). …”
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