A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetes by Valentina Codazzi, Nicola Baldoni, Giulia M. Scotti, Anna Giovenzana, Andrea Rigamonti, Giulio Frontino, Eugenia Bezzecchi, Camillo Bechi Genzano, Alessandra Mandelli, Debora Carnovale, Ilaria Marzinotto, Vito Lampasona, Paolo Fiorina, Andrea Giustina, Lorenzo Piemonti, Manuela Battaglia, Marco J. Morelli, Riccardo Bonfanti, Alessandra Petrelli

“…Methods This study introduces an approach leveraging the multi-omics factor analysis (MOFA) strategy, a computational method for unsupervised integration analysis, to explore endotypes. …”
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Fine-Tuning Quadcopter Control Parameters via Deep Actor-Critic Learning Framework: An Exploration of Nonlinear Stability Analysis and Intelligent Gain Tuning by Hassan Moin, Umer Hameed Shah, Muhammad Jawad Khan, Hasan Sajid

“…The state equations are obtained using the Lagrange method, whilst the aerodynamic coefficients are computed numerically using blade element momentum theory. …”
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Discovery of selective ACAT2 antagonist via a combination strategy based on deep docking, pharmacophore modelling, and molecular dynamics simulation by Yanfeng Liu, Feng Ding, Liangying Deng, Shuran Zhang, Lixing Wu, Huangjin Tong

“…In this study, we established a multilayer virtual screening workflow and subjected biologically evaluated representative compounds to enzyme inhibitory assays. …”
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Machine Learning‐Enhanced Optimization for High‐Throughput Precision in Cellular Droplet Bioprinting by Jaemyung Shin, Ryan Kang, Kinam Hyun, Zhangkang Li, Hitendra Kumar, Kangsoo Kim, Simon S. Park, Keekyoung Kim

“…Among the five algorithms evaluated, the multilayer perceptron model demonstrates the highest prediction accuracy, while the decision tree model offers the fastest computation time. …”
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An Approach to Modeling and Developing Virtual Sensors Used in the Simulation of Autonomous Vehicles by István Barabás, Calin Iclodean, Horia Beles, Csaba Antonya, Andreia Molea, Florin Bogdan Scurt

“…The complexity of the virtual model must correspond to the reality of the evaluated system, becoming as complex as necessary and nevertheless as simple as possible, allowing for computer simulation results to be validated by experimental measurements. …”
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In vivo bone regeneration performance of hydroxypropyl methylcellulose hydrogel-based composite bone cements in ovariectomized and ovary-intact rats: a preliminary investigation by Mosharraf Hossain, Tamima Sultana, Ji Eun Moon, Soobin Im, Je Hoon Jeong

“…Two prepared biocomposites including HG/β-TCP/HA and HG/β-TCP/HA/PMMA were injected into the tibial defects of both OVX and NOVX rats for evaluating in vivo osteogenesis after 12 weeks. Micro-computed tomography and histological analysis using hematoxylin and eosin (H&E) and Masson's trichrome stains of the two composite cements implanted into the tibial defects of OVX and NOVX rats revealed enhanced bone regeneration potential. …”
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Annotated intraoral image dataset for dental caries detection by Syed Muhammad Faizan Ahmed, Muhammad Huzaifa Ghori, Aamna Khalid, Ayesha Nooruddin, Niha Adnan, Abhishek Lal, Fahad Umer

“…Five AI models (YOLOv5s, YOLOv8s, YOLOv11, SSD-MobileNet-v2, and Faster R-CNN) were trained and evaluated, with YOLOv8s achieving the best performance (mAP = 0.841 @ 0.5 IoU). …”
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How does digitalization promote productivity growth in China? by Kaixuan Bai, Zhiyang Shen, Shuyuan Zhou, Zihan Su, Rongrong Yang, Malin Song

“…In the context of Industry 4.0, advancements in computer technology and the digital revolution have profoundly impacted global economic growth. …”
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A Hybrid Deep Learning Model for Waste Detection and Classification Utilizing YOLOv8 and CNN by Ain Atiqa Mustapha, Sarah ‘Atifah Saruchi, Heru Supriyono, Mahmud Iwan Solihin

“…The effectiveness of the hybrid model is evaluated using a specialized dataset related to waste recycling, which demonstrates significant improvements compared to individual models. …”
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Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer by Li Ning, Li Ning, Xiu Li, Xiu Li, Yating Xu, Yating Xu, Yu Si, Yu Si, Hongting Zhao, Qinling Ren, Qinling Ren

“…Immunogenic cell death-related features (ICDRs) were constructed using multiple machine algorithms, and ICDRs were evaluated in training and validation sets to provide quantitative tools for predicting prognosis in clinical practice. …”
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The Role of Quantitative Assessment of Visceral Adipose Tissue of the Heart as a Predictor for Cardiovascular Events by V. Yu. Chernina, S. P. Morozov, L. A. Nizovtsova, I. A. Blokhin, D. I. Sitdikov, V. A. Gombolevskiy

“…Objective of this article – to evaluate possibilities to visualize cardiac visceral adipose tissue by echocardiography, computed tomography (CT), and magnetic resonanse imaging (MRI) and to systematize data on its physiological and pathological roles. …”
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Digital phenotyping as a new method of screening for mental disorders by E. D. Kasyanov, Ya. V. Kovaleva, G. E. Mazo

“…Digital phenotyping is one of the clinical tools in the field of information technology that allows you to evaluate a person’s phenotype using various personal information devices, such as a smartphone, tablet, smartwatch, various sensors and other computer tools. …”
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Acute pulmonary embolism treatment in lung transplant recipients: mechanical thrombectomy and catheter directed thrombolysis by Ahmad Arar, Samuel L. Rice, Mhd Wisam Alnablsi, Akhilesh Pillai, Jamaal Benjamin, Rehan Quadri, Daniel Lamus, Anil Pillai

“…Follow-up assessments encompassed a minimum of one year and up to 3 years post-treatment, evaluating various parameters including ICU stay, ventricular pressures, pulmonary function, and laboratory tests. …”
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The Integration of AI into the Nursing Process: A Comparative Analysis of NANDA, NOC, and NIC-Based Care Plans by Ester Gilart, Anna Bocchino, Patricia Gilart-Cantizano, Eva Manuela Cotobal-Calvo, Isabel Lepiani-Diaz, Daniel Román-Sánchez, José Luis Palazón-Fernández

“…The experts established the referral plans using the Delphi technique. Responses were evaluated with a validated rubric (EADE-2) and analyzed using nonparametric tests. …”
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Usefulness of an intraoperative flipped monitor in laparoscopic surgery with situs inversus totalis: a case report of laparoscopic-assisted ileocecal resection by Ryoma Yokoi, Jesse Yu Tajima, Shigeru Kiyama, Masahiro Fukada, Ryuichi Asai, Yuta Sato, Itaru Yasufuku, Yoshihiro Tanaka, Naoki Okumura, Katsutoshi Murase, Takao Takahashi, Nobuhisa Matsuhashi

“…Case presentation A 41-year-old man with SIT was diagnosed with an appendiceal tumor and underwent laparoscopic-assisted ileocecal resection. Preoperatively, we evaluated anatomical variations using 3D-computed tomography and simulated mirror images by watching flipped videos of patients with normal anatomy undergoing similar operations. …”
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Surgical treatment of a patient with a comminuted fracture of the scapula (clinical observations) by A. A. Prokhorov, S. V. Novikov, N. N. Karchebnyy, A. N. Mironov, M. A. Panin, A. S. Petrosyan, V. E. Dubrov

“…After a preliminary analysis of the computed tomography data, the surgical technique protocol and the choice of implants were determined. …”
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Effect of Disk Friction Loss Reduction on Flow Phenomena in Low-specific Speed Centrifugal Pump: An Experimental and Numerical Approach by D. Satish, A. Doshi, M. Bade

“…In this research article, a low NS = 19 rpm centrifugal pump was evaluated using computational fluid dynamics (CFD) and experimental analysis at different 1000, 900 and 800 rpms over a range of flow rates (Q). …”
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Fundamentals of Innovative Aircraft Heat Exchanger Integration for Hydrogen–Electric Propulsion by Bernhard Gerl, Matthias Ronovsky-Bodisch, Niccoló Ferrari, Martin Berens

“…A correlation between the fan pressure ratio, flight speed, and exchangeable fuel cell heat is established, providing a simplified computational approach for evaluating feasible operating conditions within this process. …”
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Wear Characteristics of Spark Plasma Sintered Lightweight High Entropy Alloys: A Short Review by Kazeem Oladiti Sanusi, Nicholus Malatji, Mxolisi Brendon Shongwe, Samson Olaitan Jeje, Lehlogonolo Rudolf Kanyane

“…The prospects for HEAs include chances for innovative alloy compositions, the use of computational modeling, and an emphasis on sustainability. …”
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Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities by Stošić Srđan, Juković Mirela, Golubović Jagoš, Panjković Milana, Stojanović Sanja

“…Imaging modalities like computed tomography (CT) and MRI play a crucial role in evaluating the degree of neo-plastic extension and potential calvarial and dural invasion, thus being of significant importance in preoperative planning and management.…”
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