Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…Man Ni,1,2 Weilong Peng,1,2 Xiaoguang Wang,1,2 Jingui Li1,2 1School of Veterinary Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, People’s Republic of China; 2Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, 225009, People’s Republic of ChinaCorrespondence: Jingui Li, School of Veterinary Medicine, Yangzhou University, No. 48, Daxue North Road, Hanjiang District, Yangzhou City, Jiangsu, 225009, People’s Republic of China, Email jgli@yzu.edu.cnPurpose: An increasing proportion of the aging population has led to a rapid increase in the number of elderly patients with ulcerative colitis (UC). …”
Get full text

A new conceptual model for seed germination and seedling tillering of winter wheat in the field by Jinping Chen, Peter A. Whalley, Zhongyang Li, Xiaoxian Zhang, Malcolm J. Hawkesford, W. Richard Whalley

Get full text

Russian Strategy for Eurasian Integration: Key Elements, Determinants and Prospects for Development by D. S. Alekseev

“…Eurasia is gradually turning into the point of intersection of various longterm political and economic initiatives undertaken by the leading actors of contemporary international relations, including the Russian Federation, the European Union, the United States and the People’s Republic of China. This trend compounded by a complicated dynamics of integration and disintegration processes in the post-Soviet states further exacerbates tensions in the region, already fraught with conflict. …”
Get full text

Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury by Zhu Y, Xu G

“…Yan Zhu,1,2 Gaosi Xu1,2 1Department of Nephrology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, Jiangxi Province, People’s Republic of China; 2Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, People’s Republic of ChinaCorrespondence: Gaosi Xu, Email gaosixu@163.comAbstract: Podocyte injury was widely recognized as a fundamental mechanism driving the progression of focal segmental glomerulosclerosis (FSGS). …”
Get full text

Investigation of reactive power referring to recent studies of time-averaged stored energy density by Jiangwei Chen, Jiacheng Qiu

Get full text

Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation by Cao R, Jing J, Ma Y, Qi W, Huang X, Zhang C, Lu Z, He J, Wang G, Ma Y, Zhang H

“…Run Cao,1,* Jing Jing,1,* Yuting Ma,1,2,* Wenqing Qi,1 Xinyu Huang,1 Chaofang Zhang,1 Zhizhuo Lu,1 Jiayi He,1 Guiling Wang,1 Yuanfang Ma,1 Hailong Zhang1 1Joint National Laboratory for Antibody Drug Engineering, the First Affiliated Hospital, Henan University, Kaifeng, Henan, People’s Republic of China; 2Xuzhou Central Hospital, Xuzhou, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Zhang; Yuanfang Ma, Joint National Laboratory for Antibody Drug Engineering, the First Affiliated Hospital, Henan University, Kaifeng, Henan, People’s Republic of China, Email hailong6891@163.com; mayf@henu.edu.cnPurpose: Metformin (Met) is widely used to treat a variety of diseases, but its role in ulcerative colitis (UC) has not been fully elucidated. …”
Get full text

Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections by Yan T, Wang Q, Ma C, Teng X, Gong Z, Chu W, Zhou Q, Liu Z

“…Tao Yan,1,2 Qiuyan Wang,2 Chengcheng Ma,2 Xuan Teng,2 Zhen Gong,2 Wenwen Chu,2 Qiang Zhou,2 Zhou Liu1 1Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, 230031, People’s Republic of China; 2Department of Clinical Laboratory, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of ChinaCorrespondence: Zhou Liu, Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, People’s Republic of China, Email liuzhou0112@ahmu.edu.cnPurpose: Klebsiella pneumoniae is a globally prevalent pathogen responsible for severe hospital- and community-acquired infections, and presents significant challenges for clinical management. …”
Get full text

Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review by Gao A, Tian X, Lang D, Chen Y

“…Aili Gao, Xin Tian, Dexiu Lang, Yue Chen Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Yue Chen, Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, People’s Republic of China, Tel/Fax +86-020-83593472, Email cheny767@mail3.sysu.edu.cnAbstract: Scleromyxedema (SM) is a rare primary cutaneous mucinosis characterized by systemic papules and scleroderma-like manifestations, often associated with monoclonal gammopathy. …”
Get full text

Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. …”
Get full text

Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…Hong Liu,1,* Manxue Mei,1,* Hua Zhong,2 Shuyin Lin,1 Jiahui Luo,1 Sirong Huang,1 Jiuyao Zhou1 1Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2Department of Gerontology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiuyao Zhou, Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China, Email yaoli@gzucm.edu.cn, zhoujiuyao@vip.tom.comBackground: Chronic kidney disease (CKD) is a progressive condition that arises from diverse etiological factors, resulting in structural alterations and functional impairment of the kidneys. …”
Get full text

Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Shuyu Zheng,1,2 Zejuan Xie,1 Ziao Zhou,1 Shanshan Wang,1 Yanlin Xin,1 Jiamin Lin,1 Keyu Cheng,1 Tianming Lu,1 Ruogu Qi,1 Yuanyuan Guo1 1Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang Province, 310009, People’s Republic of ChinaCorrespondence: Ruogu Qi; Yuanyuan Guo, Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China, Email rqi@njucm.edu.cn; guoyy@njucm.edu.cnPurpose: Metastatic non-small cell lung cancer (NSCLC) remains a global health threat, with patients facing inevitable disease progression despite standard-of-care therapy. …”
Get full text

Development and Validation of a Nosocomial Infection Nomogram Model in the NICU: A Novel and Nurse-Led Way to Prediction in Preterm Infants by Shang Y, Chen L, Hu X, Zhang K, Cheng Q, Shui X, Deng Z

“…Yanyan Shang,* Ling Chen,* Xindie Hu, Keqian Zhang, Qian Cheng, Xiaoyu Shui, Zhiyue Deng Department of Neonatology, Renmin Hospital of Wuhan University, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiyue Deng; Xiaoyu Shui, Department of Neonatology, Renmin Hospital of Wuhan University, Wuchang District, Jiefang Road, No. 99, Wuhan, Hubei, 430060, People’s Republic of China, Tel +86 18086403090, Email 2015302180361@whu.edu.cn; 15926276672@163.comPurpose: Nosocomial infections (NI) are a leading cause of mortality in preterm infants in the Neonatal Intensive Care Unit (NICU). …”
Get full text

Chronic Stress Mediates Inflammatory Cytokines Alterations and Its Role in Tumorigenesis by Liu Z, Lei M, Bai Y

“…Zhihan Liu,* Meng Lei,* Yanxia Bai Department of Otorhinolaryngology-Head & Neck Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanxia Bai, Department of Otorhinolaryngology-Head & Neck Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, Tel +86 85323965, Email yanxiabai@xjtufh.edu.cnIntroduction: Prolonged psychological stress is closely associated with cancer due to its role in promoting the release of stress hormones through the sustained activation of the sympathetic-adrenal-medullary system. …”
Get full text

Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

“…Dehong Wu,1,* Mengdi Yin,2,* Dandan Cao,2,* Xiafeng Zhang,2 Yichun Zhu,2 Ying Wei,2 Yiling Li,2 Chengping Wen,2 Jia Zhou2 1Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310005, People’s Republic of China; 2Institute of Basic Research in Clinical Medicine, College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jia Zhou; Chengping Wen, Email zhoujia@zcmu.edu.cn; chengpw2010@126.comBackground: Rheumatoid arthritis (RA) is a chronic autoimmune disease and increasing evidence suggests that disturbances in the composition and function of gut microbiota are potentially implicated in the progression of RA. …”
Get full text

National Patient Satisfaction Survey as a Predictor for Quality of Care and Quality Improvement – Experience and Practice by Cui J, Du J, Zhang N, Liang Z

“…Juan Cui,1,2 Jing Du,2 Ning Zhang,1 Zhanming Liang3 1Affairs Management Office, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong Province, People’s Republic of China; 2Department of Medical Management, Health Commission of Shandong Province, Jinan, Shandong Province, People’s Republic of China; 3College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, AustraliaCorrespondence: Ning Zhang, Email zn394114326@126.comBackground: Patient satisfaction is an important predictor of quality of care and hospital services. …”
Get full text

Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients by Wang M, Tang J, Pan Z, Jiang H, Hu D, Zhu B, Liang Z, Zhao X, Li Y

“…Mengxia Wang,1,* Jieke Tang,1,* Zhaojie Pan,2 Hongxue Jiang,1 Donghua Hu,1 Beibei Zhu,2 Zhaojia Liang,1 Xiangfeng Zhao,1 Yalan Li1 1Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China; 2Department of Digestive Endoscopy Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yalan Li, Department of Anesthesiology, The First Affiliated Hospital of Jinan University, No. 613, Huangpu West Avenue, Tianhe District, Guangzhou, Guangdong Province, 510630, People’s Republic of China, Email tyalan@jnu.edu.cnPurpose: The provision of comfortable and safe environment for painless gastroscopy in obese patients is an urgent clinical problem. …”
Get full text

A Novel Nomogram for Predicting the Risk of Pneumonia After Intracerebral Hemorrhage by Sun Y, Zhang L, Huang B, He Q, Hu B

“…Yuanyuan Sun,* Lei Zhang,* Baisong Huang, Quanwei He, Bo Hu Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Quanwei He; Bo Hu, Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan , 430022, People’s Republic of China, Tel +8613554111043 ; +8613707114863, Email hequanwei2008@126.com; hubo@mail.hust.edu.cnBackground: Pneumonia is among the most dangerous complications of infection after intracerebral hemorrhage. …”
Get full text

Screening and Identification of Antipyretic Components in the Postfrost Leaves of Morus alba Based on Multivariable and Continuous-Index Spectrum-Effect Correlation by Yongsheng Qu, Liang Wang, Wei Guo

“…In ancient Chinese materia medica and the current Pharmacopoeia of the People’s Republic of China, LMA are recorded to be harvested after frost for medicinal purpose. …”
Get full text

Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…Xiuqi Li,1,* Shupeng Liu,1,* Mengyang Yu,1 Wanlin Xi,1 Xiaofei Wu,1 Dan Liu,2 Aijing Liu,1 Hongyun Wang1 1Clinical Pharmacology Research Center, Peking Union Medical College Hospital, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People’s Republic of China; 2School of Life Science and Biopharmaceuticals, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongyun Wang, Email wanghy@pumch.cnBackground: Proton pump inhibitors (PPIs) and potassium competitive acid blockers (P-CABs) are widely used to treat acid-related diseases (ARDs). …”
Get full text

Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry by Huijun Li, Jieshan Wu, Chao Chen, Wenfeng Xin, Wensheng Zhang

Get full text