Protective Effect of Resveratrol on Exercise-induced Kidney Injury in Rats by Regulating Keap1-Nrf2 Signaling Pathway by Haitao ZHOU, Ge HU, Jing ZHANG, Qiyun ZHOU, Fei QIN

“…Objective: To investigate the protective mechanism of resveratrol on exercise-induced kidney injury in rats. Methods: Thirty-two 7-week-old SPF-grade male SD rats were randomly assigned to four groups: control group (CONT, n=8), resveratrol group (RESV, n=8), exercise-induced kidney injury model group (EIKIM, n=8), and resveratrol-treated exercise-induced kidney injury group (REIKIM, n=8). …”
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Cifoplastia con silicona (elastoplastia) versus cifoplastia tradicional con cemento para fracturas vertebrales osteoporóticas. ¿Esta nueva técnica reduce las complicaciones? by R. Luque, D. Garríguez, P. Checa Betegon, M. Sanchez, M. Olvera, J.L. Perez Gonzalez, I. Dominguez Esteban

“…However, long-term results in terms of pain relief and quality of life are similar, making both treatments equally valid.…”
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Acupuncture Modulates Spatiotemporal Neuronal Dynamics in Mild Cognitive Impairment: A Protocol for Simultaneous EEG-fMRI Study by Li YQ, Chen ZW, He H, Liu YW, Ye F, Yang ZQ, Li DH, Bao QN, Zhang XY, Zhong WQ, Wu KX, Yao J, Xu P, Yang SQ, Wang ZW, Yin ZH, Liang FR

“…However, no studies have investigated the detailed mechanisms underlying this effect.Methods: This randomized controlled neuroimaging trial will enroll 60 patients with MCI, who will be randomly assigned to one of two groups: a real acupuncture (RA) group or a sham acupuncture (SA) group. …”
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Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence by Liu B, Bao Z, Chen W, Xi X, Ge X, Zhou J, Zheng X, Zhang P, Deng W, Ding R, Zhou M, Fang J

“…We aimed to explore the applicability of tNGS in the co-detection of the responsible pathogens, antimicrobial resistance (AMR) genes, and virulence genes in patients with pneumonia.Methods: A prospective study was conducted among patients with suspected pneumonia at Ruijin Hospital from March 1 to May 31, 2023. …”
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The efficacy of moxibustion on the pressure pain threshold and substance P / leukotriene B4 contents in serum to patients with rheumatoid arthritis by Siyu Tao, Yi Yang, Jie Tang, Xue Wang, Nannan Jiang, Yuan Li, Ping Wu

“…Objective: To observe the effects of moxibustion on pressure-pain thresholds (PPTs) in affected joints and non-joint areas, as well as the contents of substance P (SP) and leukotriene B4 (LTB4) in serum of patients with rheumatoid arthritis (RA), and to explore the analgesic mechanism of moxibustion in RA patients. Methods: A total of 72 patients with RA were randomly and equally classified into the control and treatment groups. …”
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Effect of Different Doses of Intrathecal Nalbuphine as Adjuvant to Hyperbaric Bupivacaine on Characteristics of Subarachnoid Block in Pelvic and Lower Limb Orthopaedic Surgeries: A... by Anupama Kumari, Shraddha Jogani, Nilesh Shah, Sara Mary Thomas

“…Patients with American Society of Anaesthesiologists (ASA) I/II status were randomly allocated into two equal groups of 20 each. Group-R received 0.75% hyperbaric ropivacaine 3.5 mL+0.1 mL normal saline (total 3.6 mL) and Group-L received 0.5% hyperbaric levobupivacaine 3.5 mL+0.1 mL normal saline (total 3.6 mL). …”
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Second Victim Syndrome Among Healthcare Professionals: A Systematic Review of Interventions and Outcomes by Ong TSK, Goh CN, Tan EKYE, Sivanathan KA, Tang ASP, Tan HK, Ng QX

“…This systematic review aimed to synthesize the evidence on the outcomes of available interventions targeting SVS.Methods: We systematically searched MEDLINE, Embase, and the Cochrane Library databases, covering all records up to July 7, 2024. …”
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Influence of Noninvasive Respiratory Support Techniques on Gas Exchange in Cardiac Surgical Patients Suffering from Post-Operative Respiratory Failure by A. A. Eremenko, Р. V. Polyakova, M. A. Vyzhigina

“…PaO2/FiO2 during low-flow oxygen therapy was equal to 171 (137–243) mm Hg. At the background of HFNC, this index increased to 235 (183–305) mm Hg (P=0.00004), and upon transfer to NIPPV — to 228 (180–288) mm Hg (P=0.000028). …”
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Effects of exercise intensity on soleus muscle myostatin and follistatin levels of hyperglycaemic rats (Efectos de la intensidad del ejercicio sobre la miostatina y folistatina de... by Sepideh Azhir, Eidy Alijani, Sergio Francisco Martínez Huenchullán, Hamid Amni, Julien Baker, Farid Farhani

“…The total distance covered per session in MICT and HIIT was equal. 48 hours following the last training session, rats were anesthetized and soleus muscles were excised. …”
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TRAP1 Improves Diabetic Retinopathy by Preserving Mitochondrial Function by Li Y, Xu W, Zhao G, Guo Y, Wang L, Du Q, Fei Y, Hu X, Hu H, Chen L, Xu Y

“…Tumor necrosis factor-associated protein 1 (TRAP1), a mitochondrial chaperone regulating stress responses, remains unexplored in DR pathogenesis.Methods: We established in vivo and in vitro models of DR. …”
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Investigation into the Efficacy of Formic Acid Fumigation for Inactivating Clinically Isolated Filamentous Fungi by Yuan K, Tian B, Zhan A, Chen Z, Ye L, Ling Y, Liu S, Bai X, Zhao Y

“…We aim to develop an efficient inactivation protocol for molds and provide valuable insights into laboratory techniques for fungal inactivation.Methods: Initially, 238 clinical isolates from 23 species of molds were evaluated for the inactivation efficacy of formic acid, formaldehyde, and peracetic acid. …”
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Chinese Massage (Tuina) Attenuates Knee Osteoarthritis by Modulating Autophagy-Related Cytokines: A Multidisciplinary Methodological Investigation by Wang Z, Zhao C, Li M, Zhang L, Diao J, Wu Y, Yang T, Shi M, Lei Y, Wang Y, Li M, Bian Y, Zhou Y, Xu H

“…Zhen Wang,1,* Chi Zhao,1,2,* Mengmeng Li,1,2,* Lili Zhang,1,* Jieyao Diao,1 Yiming Wu,2 Tao Yang,2 Mingwei Shi,2 Yang Lei,2 Yu Wang,3 Miaoxiu Li,4 Yanqin Bian,5 Yunfeng Zhou,1 Hui Xu1,2 1College of Acupuncture and Massage, Henan University of Chinese Medicine, Zhengzhou, People’s Republic of China; 2Acupuncture and Massage Department, The Third Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, People’s Republic of China; 3College of Computer Science, Xidian University, Xian, People’s Republic of China; 4College of Acupuncture and Massage, Shanghai University of Chinese Medicine, Shanghai, People’s Republic of China; 5Orthopaedic Research Laboratory, University of California, Davis, CA, USA*These authors contributed equally to this workCorrespondence: Hui Xu, Email 15036065036@163.comBackground: Tuina therapy has demonstrated its potential in modulating autophagy-related factors in knee osteoarthritis (KOA); however, its core therapeutic targets and specific mechanisms require systematic elucidation through interdisciplinary research.Objective: This study investigated the mechanism by which Tuina alleviates KOA progression using multidimensional approaches, including Mendelian randomization (MR), in vivo experiments, and machine learning.Methods: Genetic data from genome-wide association studies of 60 cytokines and KOA were analyzed using MR analysis to identify autophagy-related factors significantly associated with KOA. …”
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Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model by Zhang K, Zhou F, Zhu C, Yuan L, Li D, Wang J, Lu W

“…Therefore, in the present study, we chose digoxin as the inhibitor to investigate whether HIF-1α contributes to the progression in a mouse model of COPD and possible mechanism.Methods: The COPD model was established by cigarette smoke (CS) exposed; animals were intragastrically treated with vehicle or different doses of digoxin (0.02 mg/kg and 0.1 mg/kg). …”
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Uso de Moodle para fortalecer competencias ciudadanas en estudiantes de fisioterapia: un diseño pretest-postest (Use of Moodle to strengthen citizenship competencies in physiother... by Milena Boneth-Collante, Jorge Salazar-Rodríguez, Adriana Angarita-Fonseca

“…In the analysis by subgroups, it was found that those who obtained a score equal to or less than 60 in the initial evaluation significantly improved their knowledge [pretest = 51.6 (9.9), posttest = 60 (15.1), p-value = 0.018]. …”
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Xietu Hemu Prescription Improves Metabolic Dysfunction-Associated Steatotic Liver Disease: A Real-World Cohort Study by Xiang LL, Cao YT, Wang XX, Wang GX, Zhang YJ, Li RH, Qi F, Huai JX, Sun J, He XJ, Zhou XQ

“…Liu-lan Xiang,1,2,* Yu-tian Cao,1,2,* Xiao-xiao Wang,3,* Gao-xiang Wang,1,* Yu-juan Zhang,4 Rui-han Li,1,2 Fang Qi,5 Jia-xuan Huai,1,2 Jing Sun,1,2 Xiao-jin He,3 Xi-qiao Zhou1 1Department of Endocrinology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, People’s Republic of China; 2The First Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 3Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, People’s Republic of China; 4Department of Endocrinology, Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 5Department of Geriatrics, Panjin Liao-Oil Field Gem Flower Hospital, Liaoning, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xi-qiao Zhou, Email zhouxiqiao@njucm.edu.cn Xiao-jin He, Email xomaestro@163.comPurpose: This study aims to evaluate the efficacy of the Xietu Hemu prescription (XHP) in improving metabolic dysfunction-associated steatotic liver disease (MASLD) through a Real World Study approach.Methods: This was a single-center, prospective, real-world cohort study of 262 patients with MASLD who met the inclusion and exclusion criteria from November 2021 to November 2023 at Jiangsu Provincial Hospital of Traditional Chinese Medicine. …”
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Adverse drug reactions and contributing factors in patients with drug-resistant tuberculosis: A 7-year retrospective cohort study in Addis Ababa, Ethiopia by Bisrat Solomon, Yimtubezinash Woldeamanuel, Tigest Ajeme, Mbazi Senkoro, Tsegahun Manyazewal

“…Factors associated with adverse drug reactions were hospitalization (AHR = 1.53, 95 % CI: 1.10–2. 13), baseline anemia (AHR = 1.58, 95 % CI: 1.16–2.17), the age group of 25–49 years (AHR = 1.53, 95 % CI: 1.05–2.21), and age greater than or equal to 50 years (AHR = 1.87, 95 % CI: 1.19–2.93). …”
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The observance of maternal rights charter in labor with postpartum anxiety in mothers delivering at maternity hospitals by Marziye Shahpari, Mahnaz Zarshenas, Marzieh Akbarzadeh

“…Maternal rights in the physical aspect were observed equally by the midwife instructor, staff, and residents. …”
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PLATINUM-BASED CHEMORADIOTHERAPY AS DEFINITIVE TREATMENT IN ADVANCED SQUAMOUS CELL CARCINOMA OF HEAD AND NECK IN REAL-WORLD SETTING by Hadila da Silva Veras Sousa, Vivian Naomi Horita, Matheus Yung Perin, Daniel Naves Araújo Teixeira, Joyce Gruenwaldt, Eduardo Baldon Pereira, Carlos Takahiro Chone, Gustavo Jacob Lourenço, Ligia Traldi Macedo, Carmen Silvia Passos Lima

“…Survival outcomes were estimated with the Kaplan-Meier method, and statistical comparisons were performed using the log-rank test and Cox proportional hazards regression for univariate and multivariate analyses. …”
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Predicting Sleeping Disorders After mTBI: A Role for Inflammation and Brain Network Biomarkers by Du R, Yu Y, Zhu X, Wang R, Yang Y, Li Y, Zhang S, Su H

“…Rui Du,1,* Yue Yu,1– 4,* Xiwen Zhu,2 Ranchao Wang,1 Yu Yang,1 Yang Li,1 Subo Zhang,3 Hui Su4 1Department of Radiology, Zhenjiang First People’s Hospital, Zhenjiang, Jiangsu, People’s Republic of China; 2Department of Surgery, Lishui People’s Hospital, Nanjing, Jiangsu, People’s Republic of China; 3Department of Radiology, The Second People’s Hospital of Lianyungang, Lianyungang, Jiangsu, People’s Republic of China; 4Department of Radiology, Gaoyou People’s Hospital, Yangzhou, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Subo Zhang, Department of Radiology, The Second People’s Hospital of Lianyungang, No. 41 Hailian East Road, Haizhou District, Lianyungang, Jiangsu, People’s Republic of China, Tel +0518-85775003, Email zhangsubolyg@126.com Hui Su, Department of Radiology, Gaoyou People’s Hospital, No. 10, Dongyuan Road, Gaoyou, Jiangsu, People’s Republic of China, Tel +86 18852869930, Email 18852869930@163.comPurpose: To predict the occurrence of sleeping disorders (SD) in patients with mild traumatic brain injury (mTBI) 3 months after injury.Methods: This study recruited a total of 232 patients with mTBI and underwent a three-month follow-up period. …”
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Small fiber damage in patients with chemo-induced polyneuropathy by O. A. Tikhonova, D. S. Druzhinin, O. P. Tuchina, A. V. Vinogradova, S. A. Doktorova, M. I. Dolgaleva, A. M. Tynterova

“…To evaluate the changes in the number of thin fibers in patients with chemotherapy‑induced polyneuropathy and oncological diseases of the gastrointestinal tract (GIT) and pelvic organs (PO), as well as to analyze the relationship of fiber density with clinical and neurophysiological parameters and neuropathic pain syndrome.Materials and methods. The study included 34 patients over 18 years old, divided equally into two groups: the first group – patients with GIT organs cancer, in which oxaliplatin was the main drug; the second group – patients with PO cancer, in which paclitaxel/docetaxel was the main drug. …”
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