Assessment of Birth Preparedness and Complication Readiness among Pregnant Women: A Cross-sectional Study by T Elamathi, K Ananthi, Rimi Singh

“…Patients with American Society of Anaesthesiologists (ASA) I/II status were randomly allocated into two equal groups of 20 each. Group-R received 0.75% hyperbaric ropivacaine 3.5 mL+0.1 mL normal saline (total 3.6 mL) and Group-L received 0.5% hyperbaric levobupivacaine 3.5 mL+0.1 mL normal saline (total 3.6 mL). …”
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Antimicrobial activity of copper-nickel coated door handles: a blinded, randomized controlled study in a clinical setting by Idelevich, Evgeny A., Schlattmann, Andreas, Sauerland, Cristina, Gebert, Carsten, Becker, Karsten

“…However, the impact of reducing bacterial contamination through copper-coated surfaces remains controversial. Methods: A pilot study was set up in a blinded, randomized controlled design to elucidate the antimicrobial activity of door handles coated with a copper-nickel alloy. …”
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Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–... by Bingtian Dong, Yuping Chen, Xiaocen Yang, Zhengdong Chen, Hua Zhang, Yuan Gao, Enfa Zhao, Chaoxue Zhang

“…The incorporation of the eGDR index into predictive models significantly improved prediction performance for CVD events, with the area under the ROC and PR curves equal to or exceeding 0.90 in both the training and testing sets. …”
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Ultra-low dose dual-layer detector spectral CT for pulmonary nodule screening: image quality and diagnostic performance by Li Ding, Mingwang Chen, Xiaomei Li, Yuting Wu, Jingxu Li, Shuting Deng, Yikai Xu, Zhao Chen, Chenggong Yan

“…Abstract Objectives To investigate the image quality and diagnostic performance with ultra-low dose dual-layer detector spectral CT (DLSCT) by various reconstruction techniques for evaluation of pulmonary nodules. Materials and methods Between April 2023 and December 2023, patients with suspected pulmonary nodules were prospectively enrolled and underwent regular-dose chest CT (RDCT; 120 kVp/automatic tube current) and ultra-low dose CT (ULDCT; 100 kVp/10 mAs) on a DLSCT scanner. …”
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Alfentanil Enhanced the Sedation of Remimazolam During Anaesthesia Induction in Patients Undergoing Urological Day Surgery: A Randomised Controlled Trial by Lin Y, Chen Q, Liao Y, Xu B, Zhang C, Luo J, Liu S, Wu X, Guan X

“…The aim is to investigate whether alfentanil enhances sedative effects of remimazolam during anaesthesia induction in patients undergoing urological day surgery.Methods: This was a single-centre, single-blinded, randomised clinical trial. …”
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Inhibition of renal interstitial fibrosis by mulberry leaf alkaloids in rats with diabetic nephropathy by Feng Wu, Li Wei

“…In control group， 10 rats received a standard diet and a tail vein injection of equal volume of sodium citrate buffer simultaneously. …”
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CLINICAL ASSESSMENT OF THE EFFICIENCY OF THE APPLICATION OF THE IMPROVED TECHNIQUE OF MANUFACTURING PLASTIC BASES OF REMOVABLE DENTURES by O. A. Kryvchuk

“…The purpose of the research is to develop a clinical examination of the advanced technique for the manufacture of plate bases of removable dentures in edentulous patients. Materials and methods of the research. Clinical testing was carried out among 30 patients of middle and elderly age (60-82 years old), equal to men and women, with complete absence of teeth, who were made of two sets of removable dentures on both jaws (one by traditional method, another - by own one). …”
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The Comprehensive Analysis of Weighted Gene Co-Expression Network Analysis and Machine Learning Revealed Diagnostic Biomarkers for Breast Implant Illness Complicated with Breast Ca... by Huang Z, Wang H, Pang H, Zeng M, Zhang G, Liu F

“…This study aimed to identify the crosstalk genes between BII and BC and explored their clinical value and molecular mechanism initially.Methods: We retrieved the data from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA), and identified the differentially expressed genes (DEG) as well as module genes using Limma and weighted gene co-expression network analysis (WGCNA). …”
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Labdane Diterpenoids from <i>Leonotis ocymifolia</i> with Selective Cytotoxic Activity Against HCC70 Breast Cancer Cell Line by Jane Busisiwe Ncongwane, Vuyelwa Jacqueline Tembu, Comfort Mduduzi Nkambule, Douglas Kemboi, Gerda Fouche, Nyeleti Vukea, Jo-Anne de la Mare

“…Of the compounds extracted, 13<i>S</i>-nepetaefolin demonstrated the greatest cytotoxic activity with an IC₅₀ of 24.65 µM (SI = 1.08) against HCC70 cells; however, it was equally cytotoxic to non-tumorigenic MCF-12A breast cells (IC₅₀ of 26.55 µM), whereas its isomer (<b>2</b>) showed no activity. …”
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Core Outcome Sets for Pain Disorders: A Systematic Review of Research and Reporting Quality by Cui Y, Li B, Jiang S, Li Y, Wang S

“…Ying Cui,1– 3,&amp;ast; Bo Li,1– 3,&amp;ast; Shiyi Jiang,4 Yuxian Li,1– 3 Sixuan Wang1– 3 1Department of Acupuncture, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2Department of Acupuncture, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China; 3Department of Acupuncture, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 4Department of Rehabilitation, Wuxi Xishan District Hospital of Traditional Chinese Medicine, Wuxi, Jiangsu, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Bo Li, Department of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, No. 314, Anshan Xi Road, Nankai District, Tianjin, 300072, People’s Republic of China, Email ibou119@163.comPurpose: To systematically review the current research status of Core Outcome Sets (COS) for pain-related diseases and to evaluate the methodological quality of existing COS.Methods: Two researchers independently conducted a comprehensive search of both English and Chinese databases. …”
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4-Octyl Itaconate Modulates Dendritic Cells Function and Tumor Immunity via NRF2 Activation by Zhu B, Zhu L, Ge Z, Zheng S, Dai X, Feng D, Tan L, Sha P, Yao Y

“…In this study, we aimed to investigate the role of itaconate in regulating the maturation and function of DCs and its underlying molecular mechanism.Methods: Bone marrow-derived dendritic cells (BMDCs) were treated with 4-octyl itaconate (4OI). …”
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Machine Learning Strategies for Preoperative PJI Diagnosis: Integrative Analysis of Serum and Synovial Fluid Markers by Chen B, Yang Y, Zhou H, Li F, Shen Y, Cheng Q, Huang W, Qin L

“…This study aims to develop a new diagnostic model for the preoperative diagnosis of PJI based on serum and synovial fluid markers and further validate its effectiveness.Methods: We retrospectively collected data from patients admitted for joint revision surgery between January 2018 and October 2022, selecting serum and synovial fluid markers as variables for the study. …”
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Intranasal Dexmedetomidine for the Management of Preoperative Anxiety-Related Insomnia: A Randomized, Three-Blinded, Clinical Trial Compared with Lorazepam and Placebo by Yang WY, Huang K, Lin ZJ, Zeng W, Liu X, Liu HB, Zhong ML, Wei J, Liang WD, Wang LF, Chen L

“…Wen-yi Yang,1,&ast; Kuan Huang,2,3,&ast; Zhi-jian Lin,1 Wen Zeng,2,3 Xin Liu,2,3 Hong-bo Liu,1 Mao-lin Zhong,2,3 Jun Wei,2,3 Wei-dong Liang,2,3 Li-feng Wang,2,3 Li Chen2,3 1The First Clinical Medical College of Gannan Medical University, Ganzhou, Jiangxi, People’s Republic of China; 2Anesthesia Surgical Center, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, People’s Republic of China; 3Anesthesia Key Laboratory of Gannan Medical University, Ganzhou, Jiangxi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Li Chen, Anesthesia Surgical Center, The First Affiliated Hospital of Gannan Medical University, 23 Qingnian Road, Zhanggong District, Ganzhou, People’s Republic of China, Tel +8615727752168, Email zgx8778@126.comPurpose: To evaluate the efficacy and safety of intranasal dexmedetomidine (Dex), oral lorazepam, and a placebo in managing preoperative anxiety-related insomnia.Patients and Methods: A total of 90 patients exhibiting symptoms of preoperative anxiety and insomnia were randomly assigned to three groups: Dex (receiving 2.5 μg/kg Dex intranasally and starch tablets orally), lorazepam (receiving saline intranasally and 2 mg lorazepam orally), and placebo (receiving saline intranasally and starch tablets orally). …”
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Association Between Locoregional Private Equity Investment in Retina Practices and Academic Vitreoretinal Caseload by Franco JJ, Pan WW, Mian SI, Wubben TJ

“…Jovany J Franco,&amp;ast; Warren W Pan,&amp;ast; Shahzad I Mian, Thomas J Wubben Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA&amp;ast;These authors contributed equally to this workCorrespondence: Thomas J Wubben, Department of Ophthalmology and Visual Sciences University of Michigan Kellogg Eye Center, 1000 Wall Street, Ann Arbor, MI, 48105, USA, Email twubben@med.umich.eduPurpose: Private equity (PE) firms acquire stakes in non-publicly traded companies to generate value through operational improvements. …”
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Detectability of Iodine in Mediastinal Lesions on Photon Counting CT: A Phantom Study by Joric R. Centen, Marcel J. W. Greuter, Mathias Prokop

“…<b>Conclusions:</b> Iodine detectability with PCCT is at least equal to CCT for simulated mediastinal lesions of 1–12 mm, even at a dose reduction of 66%. …”
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Medical Insurance Reimbursement and the Effects of Tuberculosis Management in Guangxi Province, China: A Retrospective Cross-Sectional Study by Liu A, Liu S, Pan P, Liao Y, Huang J, Tang Y, Ye L, Liang H

“…Aimei Liu,1,2,&ast; Sang Liu,1,2,&ast; Peijiang Pan,3,&ast; Yanyan Liao,3 Junli Huang,2 Yucheng Tang,2 Li Ye,3,4 Hao Liang3,4 1Department of Infectious Diseases, Chest Hospital of Guangxi Zhuang Autonomous Region, Liuzhou, Guangxi, People’s Republic of China; 2Guangxi Center for Tuberculosis Control and Medical Quality, Liuzhou, Guangxi, People’s Republic of China; 3Biosafety III Laboratory, Life Science Institute, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 4Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Li Ye, Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, No. 22 Shuangyong Road, Nanning, Guangxi, TX 530000, People’s Republic of China, Email yeli@gxmu.edu.cn Hao Liang, Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, No. 22 Shuangyong Road, Nanning, Guangxi, TX 530000, People’s Republic of China, Email lianghao@gxmu.edu.cnPurpose: This study aims to compare the differences in medical insurance reimbursement for TB treatment in Guangxi and to analyze the effects of such variations, thereby contributing to the enhancement of TB care and control.Patients and Methods: A survey was conducted across 49 randomly selected TB-designated hospitals in Guangxi using structured questionnaires and patient records. …”
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DYNAMICS OF DATA OF DIFFERENTIAL WHITE BLOOD CELL COUNT IN PATIENTS WITH GENERALIZED PERIODONTITIS WITH DIFFERENT BLOOD GROUPS by Y.L. Bandrivsky

“…The material and research methods. 855 males aged 20 - 55 years were examined. …”
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Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach by Li X, Xiao Y, Yang M, Zhang X, Yuan Z, Zhang Z, Zhang H, Liu L, Zhao M

“…This study aimed to explore shared diagnostic genes, potential mechanisms, and the role of immune cells in the COPD-sepsis relationship using Mendelian randomization (MR) and bioinformatics approaches, while also identifying potential therapeutic drugs.Methods: Two-sample MR analysis was performed using genome-wide association data to assess genetically predicted COPD and sepsis. …”
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Sheng-Jiang Powder Alleviates Th17/Treg Immune Imbalance of Experimental Autoimmune Encephalomyelitis by Regulating the Fatty Acids Metabolism by Wu L, Xu H, Xia H, Peng L, Qin L, Gong Q, Zhao M, Wu Z, Zhao Y, Zheng Z

“…Sheng-Jiang powder (SJP), a traditional Chinese medicine formula, has demonstrated anti-inflammatory effects and may offer a novel therapeutic option for MS.Aim: This study aimed to investigate the therapeutic efficacy and underlying mechanism of SJP in myelin oligodendrocyte glycoprotein 35– 55 (MOG35-55)-induced experimental autoimmune encephalomyelitis (EAE) mice.Methods: The efficacy of SJP was assessed using the MOG35-55-induced EAE model. …”
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Predictive Value of Plasma D-Dimer for Cerebral Herniation Post-Thrombectomy in Acute Ischemic Stroke Patients by Zhang W, Xing W, Feng J, Wen Y, Zhong X, Ling L, He J

“…This study aims to explore the predictive value of emergency preoperative plasma D-dimer levels in cerebral herniation after successful thrombectomy.Methods: Between January 2019 and December 2023, patients with AIS who received a successful thrombectomy in our single comprehensive stroke center were retrospectively enrolled. …”
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