Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…However, there is currently no relevant research to promote gastrostomy wound treatment and tract maturation.Methods: Herein, a nanozyme loaded bioactive hydrogels (MO-HPA) was developed to accelerate tract maturation and inhibit bacteria. …”
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Decoding ARF4 and EIF5B-Based Prognostic Signatures and Immune Landscape Following Insufficient Radiofrequency Ablation in Hepatocellular Carcinoma: Through Multi-Omics and Experim... by Zhang Y, Lu Y, Zheng S, Luo W, Tan M, Luo B

“…Hence, this study seeks to pinpoint immune biomarkers to improve treatment precision and prognostic accuracy for RFA patients.Methods: The study utilized data from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and The International Cancer Genome Consortium (ICGC) database to investigate novel immune biomarkers influencing the prognosis of patients undergoing insufficient radiofrequency ablation (IRFA). …”
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Baolier Capsule’s Secret Weapon: Piperine Boosts Cholesterol Excretion to Combat Atherosclerosis by Wei M, LYu P, Li P, Hu J, Wu R, Ouyang Q, Guo K

“…This study aimed to investigate the pharmacological effects, principal active ingredients, and mechanisms of BLEC against hypercholesterolemia and AS.Methods: Adeno-associated virus tail vein injection was utilized to construct liver-specific LXRα knockout ApoE−/− mice. …”
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The Opioid-Sparing Effects of Intraoperative Esketamine Combined with Dexmedetomidine During Laparoscopic Major Abdominal Surgery: A Randomized Controlled Double-Blind Trial by Wang W, Chen Y, Li G, Chen Y, Wu J, Shi Y, Zhong M

“…However, the advantages of OS anesthesia strategy in laparoscopic abdominal major surgery are still unknown.Methods: 157 patients undergoing laparoscopic major abdominal surgery were randomly assigned to two groups: Remi (77, remifentanil) and OS (80, esketamine combined with dexmedetomidine), the drugs were administered at 0.2-0.5 mg/kg/h (remifentanil or esketamine) and 0.2-0.7μg/kg/h (remifentanil or dexmedetomidine) in two syringes, respectively The primary outcome was the numeric rating scale (NRS) pain score on postoperative day (POD)1. …”
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Dynamic Neutrophil-to-Lymphocyte Ratio at 3-4 weeks of Intensity-Modulated Radiotherapy Combined with Normal Liver Volume Predicts Radiation-Induced Hepatic Toxicity in Hepatocellu... by Chen L, Li J, Wang X, Chen S, Wu Y, Li J, Liang S

“…Lijun Chen,* Jizhou Li,* Xiaoting Wang, Shenshen Chen, Yi Wu, Jianxu Li, Shixiong Liang Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shixiong Liang, Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, People’s Republic of China, Email liangshixionglsx@163.com Jianxu Li, Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, People’s Republic of China, Email lijianxu1236@sr.gxmu.edu.cnPurpose: This study aimed to investigate whether early dynamic variation in circulating neutrophil-to-lymphocyte ratio(NLR) during intensity-modulated radiotherapy (IMRT) can predict radiation-induced hepatic toxicity (RIHT) in patients with hepatocellular carcinoma(HCC).Patients and methods: Neutrophil and lymphocyte counts of 103 HCC patients were measured every 2 weeks before, during and after completion of IMRT.Generalized estimating equations analyses was used to analyze the dynamic changes of neutrophil and lymphocyte counts. …”
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Like mother like daughter, the role of low human capital in intergenerational cycles of disadvantage: the Pune Maternal Nutrition Study by Akanksha A. Marphatia, Akanksha A. Marphatia, Jonathan C. K. Wells, Alice M. Reid, Aboli Bhalerao, Chittaranjan S. Yajnik

“…Increasing education and delaying girls' marriage may lead to sustained intergenerational improvements across Sustainable Development Goals 1 to 5, relating to poverty, hunger, health, education and gender equality.…”
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Corneal Alterations in Patients with Osteogenesis Imperfecta: An in vivo Corneal Confocal Microscopy Study by Mangiantini P, Mallone F, D’Andrea M, Albanesi L, Lucchino L, Celli L, Celli M, Lambiase A, Moramarco A

“…This study aimed to comprehensively evaluate corneal changes in a large sample of OI patients compared to controls using in vivo confocal microscopy (IVCM).Patients and Methods: Nineteen OI patients (mean age: 34.0 ± 16.00 years; 9 females, 10 males) and 20 healthy controls (mean age: 35.5 ± 12.00; 12 females, 8 males) were included, matched for age and gender. …”
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Exploring the Real Mental Experience of Patients with Moyamoya Disease: A Qualitative Analysis by Li M, Zhang W, Zhang N, Li S, Pan Z, Xiong X, Li Q, Wei J, Li H

“…Meng Li,1,* Wenling Zhang,2,* Ning Zhang,3 Shen Li,4 Zhongjie Pan,5 Xiaoyun Xiong,6 Qiong Li,3 Junfan Wei,7 Huawei Li1 1Nursing Department, The Third People’s Hospital of Henan Province, Zhengzhou, People’s Republic of China; 2Operation Department, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of China; 3School of Nursing Department, Xinxiang Medical University, Xinxiang, People’s Republic of China; 4School of Rehabilitation Department, Henan Vocational College of Tuina, Zhengzhou, People’s Republic of China; 5School of Medicine Department, Zhengzhou University of Industrial Technology, Zhengzhou, People’s Republic of China; 6Rehabilitation Medicine Department, The Third People’s Hospital of Henan Province, Zhengzhou, People’s Republic of China; 7Nursing Department, The Seventh Clinical College of Guangzhou University of Chinese Medicine, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Huawei Li, The Third People’s Hospital of Henan Province, 198 Funiu Road, Zhengzhou, Henan, People’s Republic of China, Tel +86 13937182631, Email 178065643@qq.com Junfan Wei, Guangzhou University of Chinese Medicine, No. 22,25 Yu’an 2nd Road, 30 District, Bao’an District, Shenzhen, People’s Republic of China, Tel +86 13253369959, Email weijunfan123456@163.comPurpose: The objective of this study was to explore the real mental experiences of moyamoya disease patients.Patients and Methods: A phenomenological research method was used, and participants were selected by purposive sampling from two tertiary care hospitals in Henan Province, China. …”
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Supporting Muslim undergraduate medical students through medical school: lessons from a novel, student-led case-based learning intervention by Zain Mohammed, Zain Mohammed, Hafsah Ba, Linta Nasim, Emily Roisin Reid

“…The facilitators reflected that the students-as-experts aspect of the intervention equalized the usual faculty-student power dynamics. …”
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Efficacy and Survival Analysis of Radiotherapy for Internal Mammary Lymph Nodes After Modified Radical Mastectomy for T1-3N3M0 the Lateral Quadrant Breast Cancer by Han X, Jiang D, Zhu C, Li D, Yin H

“…Xiumei Han,1,* Die Jiang,1,* Chaomang Zhu,2,* Duojie Li,1 Hongmei Yin1 1Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China; 2Anhui Provincial Key Laboratory of Tumor Evolution and Intelligent Diagnosis and Treatment, Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongmei Yin, Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, 233000, People’s Republic of China, Tel/Fax +86 182 2655 8221, Email yhm062573@163.comPurpose: This study aimed to investigate the efficacy and survival analysis of internal mammary lymph nodes (IMLNI) radiotherapy after modified radical mastectomy for T1-3N3M0 The lateral quadrant breast cancer.Materials and Methods: A total of 124 patients who underwent adjuvant radiotherapy after modified radical mastectomy for breast cancer in the First Affiliated Hospital of Bengbu Medical University were included. …”
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PD(L)1 Inhibitors Plus Lenvatinib Vs Atezolizumab Plus Bevacizumab Combined With HAIC for Unresectable HCC: A Propensity Score Matching Study by He Z, Chen H, Liang C, Tang X, Jiang L, Xie F, Liu Q, Zheng Y

“…Zhaoqian He,1– 3,* Hua Chen,1– 3,* Chen Liang,1– 3,* Xiang Tang,1– 3 Lingmin Jiang,1– 3 Feihu Xie,1– 3 Qi Liu,1– 3 Yun Zheng1– 3 1Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 2Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 3Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yun Zheng; Qi Liu, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, People’s Republic of China, Email zhengyun@sysucc.org.cn; liuqi9@sysucc.org.cnPurpose: To compare the clinical outcomes of different systemic therapies, specifically PD(L)1 inhibitors plus Lenvatinib versus Atezolizumab plus Bevacizumab, when combined with hepatic arterial infusion chemotherapy (HAIC) based on the FOLFOX regimen (oxaliplatin, fluorouracil, and leucovorin) as first line treatment for unresectable hepatocellular carcinoma.Patients and Methods: This real-world retrospective study enrolled 294 patients with unresectable HCC. …”
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Efficacy of Transcutaneous Electrical Acupoint Stimulation Applied During the Post-Anesthesia Recovery Period in Improving Postoperative Recovery Quality After Gynecological Laparo... by Zhou Z, Yang X, Shi M, Huang L, Wu D, Yang H, Zhang X

“…Zhihu Zhou,* Xiang Yang,* Min Shi, Liqiao Huang, Danping Wu, Huailong Yang, Xu Zhang Department of Anesthesiology, The Second Affiliated Hospital of Guilin Medical University, Guilin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xu Zhang, Department of Anesthesiology, The Second Affiliated Hospital of Guilin Medical University, No. 212, Renmin Road, Lingui District, Guilin, Guangxi, 541199, People’s Republic of China, Tel +86 189 3477 9973, Email zhangxu@glmc.edu.cnPurpose: Transcutaneous electrical acupoint stimulation (TEAS) has emerged as a promising non-pharmacological intervention to enhance postoperative recovery. …”
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Establishing the Median and 95% Effective Doses of Oliceridine for Immediate Post-Surgical Analgesia Following Laparoscopic Cholecystectomy: A Double-Blind, Sequential Dose-Finding... by Cao X, Xiao H, Yan H, Wei Y, Wen Q, Zhang Z, Xu G, Xu B, Chen J, Li X

“…Using Dixon and Massey’s up-and-down sequential allocation method, the median effective dose (ED50) and the dose required for 95% effective dose (ED95) were determined, alongside an evaluation of the agent’s safety profile.Methods: In this prospective trial, 82 participants scheduled for LC were enrolled and randomly assigned to receive either oliceridine or saline (control). …”
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Comparative effects of Zumba and Yoga on stress, body satisfaction, and self-esteem in working women: a randomized control trial by Noortje Anita Kumaat, Afif Rusdiawan, Procopio B. Dafun JR., Heri Wahyudi, Popy Elisano Arfanda, Fransisca Januarumi Marhaendra Wijaya, Himawan Wismanadi, Ary Artanty

“…Conclusions. Yoga and Zumba are equally effective, culturally adaptable interventions for improving psychological well-being and reducing stress among working women. …”
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Experiences, Challenges, and Needs of People Living with HIV in Hunan Province, China: A Qualitative Study by Shi C, Li X, Dai Y, Chen M, Mao L, Zhou X, Lei Y, Yuan W

“…Colaizzi’s seven-step analysis method and NVivo 14 was used to analyze the transcripts.Results: The participants, aged 23 to 83 years, had been living with HIV for durations ranging from one month to 19 years. …”
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Incomplete Thermal Ablation-Induced FOXP4-Mediated Promotion of Malignant Progression in Liver Cancer via NDST2 by Wan W, Pan Y, Pang J, Bai X, Li L, Kang T, Chen J, Wen R, Wen D, Yang H, He Y

“…We investigated the mechanism by which Forkhead box P4 (FOXP4) promotes the malignant transformation of residual HCC cells through N-deacetylase and N-sulfotransferase 2 (NDST2) after incomplete thermal ablation.Methods: The clinical significance of FOXP4 and NDST2 in HCC was evaluated using big data analysis. …”
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A Systematic Literature Review of the Humanistic, Economic, Sociodemographic, and Environmental Burden Associated with Severe COPD by Vlachaki I, Donhauser S, Wise RA, Chen Y, Madoni A, Scaffidi Argentina U, Mir JN, Quint JK

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PRECIS-2 used as an implementation science tool for global environmental health: A cross-sectional evaluation of the Ecolectivos study protocol to reduce burning of household plast... by Lisa M Thompson, Annalyse Ferguson, Hina Raheel, Amy E Lovvorn, Mayari Hengstermann-Artiga, Maria Renee Lopez, Melinda Higgins, Eri Saikawa, Margaret A Handley

“…Four were evaluated to be equally pragmatic as explanatory-recruitment, organization, flexibility-adherence, and primary outcome. …”
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Correlation Between Intrinsic Capacity and Muscle Strength and Quality in Older Patients with Cardiovascular Disease: A Cross-Sectional Study by Yu X, Wu D, Li F, Qiao W, Chen X

“…This study aims to explore the relationship between the decline of IC, muscle strength, and muscle quality in older patients with CVD, providing a new method and basis for early recognition of IC decline in the older adults.Methods: This cross-sectional study included 475 older individuals from communities in Zhejiang. …”
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Changing Trends in the Mental Health Status of Healthcare Workers at COVID-19 Wards Three Years After the COVID-19 Pandemic Outbreak in Saudi Arabia by Alharbi SH, Almoajel AM, Tharkar S, Alharbi AH, Almutairi K, Alzaidi HA, Kattan BF

“…Sami Hamoud Alharbi,1,* Alia Mohammed Almoajel,1,* Shabana Tharkar,1 Abdullah Hamoud Alharbi,2 Khalid Almutairi,1 Hanan Abdullah Alzaidi,1 Basmah Faisal Kattan1 1Department of Community Health Science, College of Applied Medical Science, King Saud University, Riyadh, Saudi Arabia; 2Ministry of Health, Riyadh, Saudi Arabia*These authors contributed equally to this workCorrespondence: Khalid Almutairi, Department of Community Health Science, College of Applied Medical Sciences, King Saud University, Riyadh, 12372, Saudi Arabia, Email kalmutairim@ksu.edu.saBackground: The current study aimed to investigate the severity of anxiety and depression symptoms among the healthcare workers of COVID-19 wards three years after the pandemic outbreak in Saudi Arabia.Methods: An online cross-sectional survey was conducted during the fourth quarter of 2022 and early 2023 at the COVID-19 wards of public primary healthcare hospitals of the AlQassim region of Saudi Arabia. …”
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