Metformin's impact on asprosin and FBN1 expression: Potential mechanisms beyond insulin sensitivity in type 2 diabetes in rats by Ali Dashtkar, Mansour Karajibani, Mohsen Saravani, Roya zanganeh, Hamed Fanaei

“…The objective of this study is to investigate the effects of metformin on serum asprosin levels and FBN1 gene expression in white adipose tissue in male rats. Methods: Thirty-two male Wistar rats were randomly and equally divided into four groups (n = 8): 1. …”
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Epidemiological and etiological characteristics of community-acquired pneumonia in conscripts in the modern period. Comparative evaluation of the effectiveness of pneumococcal vacc... by P. V. Kulikov, S. D. Zhogolev, R. M. Aminev, K. D. Zhogolev, A. A. Kuzin, S. R. Rubova, A. N. Gorenchuk, E. A. Mikheeva

“…The purpose of the study is to analyze morbidity and to determine etiology of community-acquired pneumonia of conscripts, to examine the epidemiological effectiveness of pneumococcal conjugate and non-conjugate polysaccharide vaccines for the prevention of community-acquired pneumonia in soldiers.Materials and methods. The incidence of communityacquired pneumonia of conscripts in the period from 2008 to 2017 was examined. …”
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Impact of health intervention coverage on reducing maternal mortality in 126 low- and middle-income countries: a Lives Saved Tool modelling study by Xi-Ru Guo, Jue Liu, Hai-Jun Wang

“…Optimizing the allocation of health resources, promoting health equality, taking more decisive national, regional and global actions are urgently needed for LMICs to reduce MMR and reach the SDG Target 3.1.…”
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The treatment characteristics of oral antipsychotics in treatment of adolescents with schizophrenia in China by Huaning Wang, Yongjing Zhang, Tao Wu, Sijia Dong, Rui Chi, Kun Jiang, Hong Qiu, Wentian Dong, Tianmei Si

“…Antipsychotics were prescribed with equal or reduced dose compared to adults DDD, and good adherence observed. …”
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DYNAMICS OF HEART RATE VARIABILITY AND VENTRICULAR ECTOPIC ACTIVITY IN IVABRADINE-TREATED PATIENTS WITH CHRONIC HEART FAILURE by M. V. Surovtseva, N. A. Koziolova, A. I. Chernyavina

“…In patients with chronic heart failure (CHF) of ischemic aetiology, to assess the dynamics of heart rate variability (HRV) and ventricular ectopic activity during the complex, ivabradine-including therapy. Material and methods. In total, 90 patients with CHF and stable angina pectoris were examined. …”
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The relationship between deontic representations of adolescents and the characteristics of their self-attitude by N.V. Lukyanchenko, L.S. Zakharova, M.I. Alikin

“…Panteleev; "The Self-Concept Scale for Children" (the "Piers-Harris Children's Self-Concept Scale" method by E. Pierce and D. Harris, adapted by A.M. …”
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A comparative perception and impact of pictorial warnings on cigarette packaging among Malaysian smokers and non-smokers by Nurul Asyikin Yahya, Nur Aqilah Mohamed Kutty, Nurul Afira Saleh

“…This study aimed to assess the effectiveness of pictorial warnings on cigarette packaging among smokers and non-smokers. Methods A cross-sectional study using a self-administered questionnaire was conducted in Kuala Lumpur. …”
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Clinical Characteristics, Prognostic Risk Factors, and Primary Treatment for Elderly Patients with Primary Central Nervous System Lymphoma: A Seer Database-Based Research by Zhang M, Yang R, Du Y, Feng H, Liu Y, Liu H, Wu D, Niu F, He P

“…Moreover, there is currently no specific prognostic model for elderly PCNSL patients.Methods: This study retrospectively selected patients diagnosed with PCNSL between 1975 and 2016 from the National Cancer Institute Surveillance, Epidemiology, and End Results Database (SEER NCI). …”
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Internal-External Homologous Drug-Loaded Exosome-Like Nanovesicles Released from Semi-IPN Hydrogel Enhancing Wound Healing of Chemoradiotherapy-Induced Oral Mucositis by Wei X, Wang M, Dong X, He Y, Nan W, Ji S, Zhao M, Chang H, Wei H, Ding D, Chen H

“…This study aimed to develop a novel therapeutic approach.Methods: We fabricated internally-externally homologous drug-loaded exosome-like nanovesicles (ORI/ENs) derived from Rabdosia rubescens and encapsulated them in a semi-interpenetrating network hydrogel system (ORI/ENs/Gel) to repair chemoradiotherapy-induced OM. …”
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Endometriosis and Mortality Risk in US Women: Findings From NHANES 1999–2006 by Liu L, Shao C, Li L, Wu N

“…We assessed the association between endometriosis and all-cause and cause-specific mortality using a retrospective cohort study design based on data from the National Health and Nutrition Examination Survey (NHANES) 1999– 2006.Materials and Methods: Both crude and multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for endometriosis and age at endometriosis with all-cause mortality were estimated using weighted Cox proportional hazards regression. …”
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Comparison of Effects of ACEIs and ARBs on Albuminuria and Hyperkalemia in Indonesian Hypertensive Type 2 Diabetes Mellitus Patients by Putri S. Agustina, Em Yunir, Pukovisa Prawiroharjo, Johanda Damanik, Rani Sauriasari

“…Therefore, it necessitates a detailed evaluation of the effects of ACEIs and ARBs on albuminuria and their side effect, hyperkalemia, specific to Indonesian T2DM patients. Methods. This cross-sectional study involved 134 T2DM patients whose treatment was restricted to either ACEIs (n = 57) or ARBs (n = 77) for at least two months before the study during May–October 2018. …”
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Exploring safety aspects of maternity care through the lens of midwifery students’ clinical experiences in Belgium, Czech republic, Estonia, Norway, Slovakia: A qualitative study by Daniela Javornická, Synnøve Mari Eidsvik Folkvord, Annelies Jaeken, Terézia Krčméryová, Helena Kisvetrová, Mary Steen

“…This paper explores aspects of maternity care services impacting patient safety as identified by midwifery students in five European countries. Methods A 2-stage qualitative design employed an interpretivist approach. …”
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Generación Z y gamificación: el dibujo pedagógico de una nueva sociedad educativa / Generation Z and gamification: the pedagogical drawing of a new educational society by Juan Carlos Manzanares Triquet

“…The educator of the 21st Century is being part of a pedagogical imbalance that crashes against the peculiarities of Generation Z students, who are eager to be part of a learning experience equal to their digital reality. Generation Z students embody some features that are requiring new ways to understand the learning process along with new tools to stimulate it. …”
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Mediators affecting the higher risk of stillbirth among foreign‐born women in Sweden: A nationwide cohort study by Minna Lundén, Ingela Hulthén Varli, Helena Kopp Kallner, Hanna Åmark

“…The risk among the other groups of foreign‐born women was, however, equal to the risk among women originating from Sweden. …”
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Evaluation of the federal hospital atlas in the context of the hospital reform 2024: a critical analysis of the healthcare provision in German hospitals by Jonas Roos, Theresa Isabelle Wilhelm, Ron Martin, Kristian Welle, Elio Assaf, Robert Kaczmarczyk

“…These results point to imbalances and underscore the need for political action to ensure equal access and high-quality hospital care across regions and providers.…”
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Predicting Drug Resistance: The Use of Novel Inflammatory Markers in Identifying ESBL-Producing Klebsiella pneumoniae by Ma X, Yuan J, Tang L, Chen X, Zhou Y, Wang N, Sun H

“…Xin Ma,1,2,* Jing Yuan,1,* Lihong Tang,1,* Xue Chen,1,* Yan Zhou,3 Ningna Wang,1 Hong Sun1 1Department of Clinical Laboratory, Urumqi Friendship Hospital, Urumqi City, Xinjiang Uygur Autonomous Region, People’s Republic of China; 2School of Basic Medicine, Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, People’s Republic of China; 3The second Medical College, Xinjiang Medical University, Laboratory Class, Karamay City, Xinjiang Uygur Autonomous Region, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Sun, Urumqi Friendship Hospital, Tianshan District, Urumqi City, Xinjiang Uygur Autonomous Region, 830049, People’s Republic of China, Tel +86-13899816208, Email 632598426@qq.comPurpose: To explore the association of the Systemic Inflammatory Response Index (SIRI) and Systemic Inflammatory Immunity Index (SII) with extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae (K. pneumoniae) and its resistance prediction.Methods: A total of 425 patients with K. pneumoniae infections were included in the study. …”
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Study on the Mechanism of UMI-77 in the Treatment of Sepsis-Induced Acute Lung Injury Based on Transcriptomics and Metabolomics by Zhang J, Xia Z, Dong C, Zhu J, Ni H, Xu Y, Xu Y

“…Although UMI-77 has demonstrated efficacy in mitigating lung injury in sepsis, the molecular mechanisms underlying its action have not yet been fully elucidated.Methods: This study aimed to delineate the mechanism by which UMI-77 counteracts sepsis-induced ALI using comprehensive transcriptomic and metabolomic analyses.Results: UMI-77 significantly ameliorated histopathological changes in the lungs of mice with sepsis-induced ALI Transcriptomic analysis revealed that 124 differentially expressed genes were modulated by UMI-77 and were predominantly implicated in chemokine-mediated signaling pathways, apoptosis regulation, and inflammatory responses. …”
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Exploration of Key Brain Regions Involved in Acupuncture and Moxibustion Analgesia: An Imaging-Based Study by He L, Zhou R, Hou S, Huang D, Zhao X, Wang M, Huang M, Yin T, Yin H, Yu S

“…Advancements in neuroimaging techniques have opened a novel pathway for investigating alterations in brain function resulting from acupuncture and moxibustion analgesia.Purpose: The purpose of this study was to investigate the brain regions activated during acupuncture and moxibustion treatment for pathological pain using neuroimaging, to better understand the underlying analgesic mechanisms.Patients and Methods: An electronic search of PubMed was conducted using the keywords “acupuncture”, “moxibustion”, “analgesia”, and “neuroimaging”. …”
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Synthesis of Zinc Oxide-Doped Carbon Dots for Treatment of Triple-Negative Breast Cancer by Wang M, Lan S, Song M, Zhang R, Zhang W, Sun X, Liu G

“…Mengqi Wang,1,* Shuting Lan,2,* Mingjun Song,3 Rongrong Zhang,2 Wenqi Zhang,2 Xiaomei Sun,2 Gang Liu2 1College of Life Science and Oceanography, Weifang University, Weifang, Shandong, People’s Republic of China; 2Key Laboratory of Medical Cell Biology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People’s Republic of China; 3College of Chemical Engineering and Environmental Chemistry, Weifang University, Weifang, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mengqi Wang; Gang Liu, Email wangmengqi@tju.edu.cn; 20190043@immu.edu.cnIntroduction: The anti-cancer properties of zinc oxide-doped carbon dots (CDs/ZnO) in inhibiting triple-negative breast cancer (TNBC) progression merit more investigation.Methods: With citric acid as the carbon source, urea applied as the nitrogen source, and zinc oxide (ZnO) used as a reactive dopant, CDs/ZnO were synthesized by microwave heating in the current study, followed by the characterization and biocompatibility assessments. …”
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Biliary Microbial Community and Metabolic Potential in Patients with Multiple Common Bile Duct Stones by Xia T, Feng S, Zou Z, Zhou J, Cai X, Ye J, Dai C

“…In this study, we aimed to investigate the characteristics and metabolic potential of biliary microbiota in patients with multiple CBDS.Methods: Eligible patients were prospectively enrolled in this study at First Affiliated Hospital of Soochow University between December 2022 and October 2023. …”
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