Modified Xi-Jiao-Di-Huang Decoction Alleviates Sepsis via Regulating Macrophage Polarization by Inhibiting the PIM2/NF-κB Pathway by Ge F, Tian F, Zhu Y, Yan Q, Sun Q, Lu J

“…The purpose of this study was to investigate the protective effects of MXJDH in septic mice and explore its mechanism of action.Methods: Utilizing UPLC-Q-TOF-MS, we identified the primary constituents of the compound MXJDH. …”
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Synthesis and electrophysical properties of nanostructured composites NіCо/BaTiO₃ and NiCo/TiO₂ by S. M. Makhno, O. M. Lisova, G. M. Gunya, P. P. Gorbyk, M. T. Kartel

“…NiCo particles were obtained by the method of chemical precipitation of nickel and cobalt carbonates in equal parts from a hydrazine hydrate solution at the temperature of 350 K. …”
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Unexpected Efficacy of Albumin-Bound Glycerol Monolaurate Against Multidrug-Resistant Bacterial Isolates: A Time-Kill Assay Study by Alrabiah MA, Hassan AA, Mubaraki MA, Albarrag AM, Dkhil MA, Somily AM, Delic D, Hafiz TA

“…Glycerol monolaurate (GML) is known for its antimicrobial properties, primarily against Gram-positive bacteria, with limited evidence of efficacy against Gram-negative pathogens.Methods: This study evaluated the antibacterial activity of GML alone and in combination with human serum albumin (HSA) against clinical isolates of carbapenem-resistant and vancomycin-resistant bacteria using MIC and time-kill assays.Results: Contrary to previous reports, we demonstrate that GML exhibits significant antibacterial activity against Gram-negative bacteria, including strains resistant to conventional antibiotics. …”
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Isoliquiritigenin Alleviates Periodontitis by Suppressing Inflammation via NF-κB Signaling Pathway of Immune Cell by Wang X, Zhao T, Liang B, Fang J, Dong Q, Chen Q

“…., Ltd, Hangzhou, 310051, People’s Republic of China; 5Centre for Bone, Joint and Sports Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, 510000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qianqian Chen; Qiu Dong, Email 18221767137@163.com; dong1005@stu2019.jnu.edu.cnBackground: Periodontitis, a chronic infectious disease, presents significant treatment challenges due to antibiotic resistance and high recurrence rates, necessitating novel therapeutics.Methods: Network pharmacology identified ISL’s potential targets in periodontitis, focusing on NF-κB signaling pathway. …”
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Inhibition of Ovarian Cancer Growth, Metastasis and Reverse the Tumor Microenvironment by Dual Drug-Loaded Polymer Micelle Targeting Tumor Microenvironment by Zhang L, Guo R, Chen M, Liu M, Liu Y, Yu Y, Zang J, Kong L, Li X

“…Transforming the immune environment from an immunosuppressive state to an anti-tumor state through the phenotypic transformation of tumor-associated macrophages is crucial for inhibiting the growth, metastasis, and recurrence of ovarian cancer.Methods: A polymer micelle (RC-PH-Ms) containing paclitaxel (PTX) and honokiol (HNK) was designed based on high expression of reactive oxygen species in the tumor microenvironment. …”
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Enhancing Periodontal Ligament Regeneration via PDLSC Delivery Using Electrospun PCL/Collagen/Cellulose Acetate Scaffolds and Collagen Hydrogel Incorporated with Curcumin-Loaded ZI... by Lan X, Wang Y, Yin M

“…This study explores a tissue engineering strategy that combines polycaprolactone (PCL)/collagen/cellulose acetate electrospun scaffolds with collagen hydrogels to deliver curcumin-loaded ZIF-8 nanoparticles fand periodontal ligament stem cells (PDLSCs).Methods: Scaffolds were fabricated via electrospinningand collagen hydrogels incorporated PDLSCs and curcumin-loaded ZIF-8 nanoparticles (CURZIF-8) were developed using cross-linking. …”
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Intravenous Versus Oral Omadacycline or Linezolid for Acute Bacterial Skin and Skin Infections: A post hoc Analysis of the OASIS Trials by George D. Rodriguez, Nathan Warren, Roman Yashayev, Surya Chitra, Maria Amodio-Groton, Kelly Wright

“…Conclusion Oral therapy is equally efficacious to IV therapy when omadacycline or linezolid is used to treat ABSSSIs. …”
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Obesity Prevalence, Associated Factors and Complications among Adult Population Attending Family Medicine Clinic in Hatta Hospital, United Arab Emirates by Ayesha Rashid, Uzma Farheen, Zahid Nabi Qureshi, Muhammad Ejaz

“…Gender distribution was kept almost equal with 50.5% male and 49.5% female participants. …”
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Excess winter cardiovascular morbidity in Ivanovo Region in 2009-2013 years by A. V. Kontsevaya, J. A. Balanova, M. M. Loukianov, M. B. Khudyakov, O. A. Belova, S. V. Romanchuk

“…To study excess cardiovascular morbidity during winter in Ivanovo Region in 2009-2013 years. Material and methods. Excess winter morbidity index (EWMI) was calculated using special formula. …”
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Exploring the Mechanism of Action of Xuebijing Injection in Treating Acute Respiratory Distress Syndrome Based on Network Pharmacology and Animal Experiments by Li J, Shen M, Yin Z

“…Jin Li,1,* Meirong Shen,2,* Zuan Yin3 1Department of Intensive Care Unit, The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang City, Jiangxi Province, 330006, People’s Republic of China; 2Department of Intensive Care Unit, Ganzhou People’s Hospital, Ganzhou City, Jiangxi Province, 341000, People’s Republic of China; 3Department of Emergency, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang City, Jiangxi Province, 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zuan Yin, Department of Emergency, Jiangxi Provincial People’s Hospital, 152 Aiguo Road, Donghu District, Nanchang City, Jiangxi Province, 330006, People’s Republic of China, Email yuzan201709@126.comObjective: To explore the mechanism of Xuebijing injection (XBJ) in treating acute respiratory distress syndrome (ARDS) using network pharmacology and animal experiments.Methods: Active ingredients of XBJ were analyzed via TCMSP, and ARDS-related targets were identified through DisGENET and Genecard. …”
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The Influence of Subclinical Hypothyroidism on Endocrine and Metabolic Characteristics in Patients with Polycystic Ovary Syndrome by Dai F, Wu Z, Qin S, Wu F, Wang M, Liu X, Liu F

“…Fang Dai,1,* Zijian Wu,2,* Shuai Qin,1 Fang Wu,3 Mingqiang Wang,4 Xiangxiu Liu,1 Fen Liu1 1Department of Endocrinology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, People’s Republic of China; 2Department of Brain surgery, The Second People’s Hospital of Guizhou Province, Guiyang, People’s Republic of China; 3Department of Obstetrics, The First People’s Hospital of Guizhou Province, Guiyang, People’s Republic of China; 4Teaching Evaluation Center, Guizhou University of Traditional Chinese Medicine, Guiyang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Dai, Department of Endocrinology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 71 Baoshan North Road, Guiyang, Guizhou, 550001, People’s Republic of China, Email 13765063256@163.comObjective: To analyze the influence of subclinical hypothyroidism (SCH) on endocrine and metabolic characteristics in patients with polycystic ovary syndrome (PCOS).Methods: A total of 198 cases of PCOS patients admitted to our hospital from January 2022 to December 2023 were selected for the study. …”
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Supporting implementation of universal prevention initiatives in K-12 schools: impacts on fidelity through organizational readiness and team functioning in a cluster-randomized tri... by Christopher M. Fleming, Hannah G. Calvert, Lindsey Turner

“…Forty public K-12 schools in Idaho, located in rural areas or townships, were recruited for the trial and were equally randomized to either the basic supports condition, including standard trainings, or to the RS3 condition. …”
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PREVALENCE OF DENTAL CARIES AND CHRONIC CATARRHAL GINGIVITIS IN SCHOOL-AGE CHILDREN IN DIFFERENT REGIONS OF UKRAINE by I.O. Trubka, O.A. Udod, N.O. Savychuk, L.V. Korniienko, S.I. Dramaretska, A.О. Savychuk

“…The prevalence of CCG in Vinnytsia among children aged 7-8 was equal to 18.7±4.5%, among children aged 12-13 – 36.0±5.5%, in Chernihiv – 31.6±7.5% and 40, 4±6.0%, in Kyiv – 22.9±6.1% and 43.3±5.0%, respectively. …”
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Relationship Between the ZJU Index and Infertility Risk in Reproductive-Aged US Women: An Analysis of NHANES 2013–2018 by Tian L, Qin X, Yang M, Tang W, Feng L, Huang J, Hu H

“…This study aims to examine the association between the ZJU index and infertility in reproductive-aged women.Methods: We conducted a cross-sectional study using data from the 2013– 2018 National Health and Nutrition Examination Survey (NHANES). …”
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Assessment of a patient safety culture: a nationwide cross-sectional study comparing public and private hospitals in Kuwait by Fatemah M. Alsaleh, Shaikha Albraikan, Hadeel Alzoubi, Eman A. Abahussain, Hossam Elamir

“…Results A total of 890 questionnaires were distributed equally between the public and private sectors. The overall response rate was 94.9%. …”
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HUMAN RIGHTS: PHILOSOPHICAL AND LEGAL ANALYSIS by ALBOV A.P.

“…Human rights must be considered as the most important ontological element of the law itself, which is based on the concept of justice, equality and freedom, and, therefore, positive national and international law cannot contradict basic human rights. …”
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Dynamic risk and protective factors in mentally disordered offenders: forensic psychiatry treatment monitoring, prison release and length of stay by Kerstin Weber, Lena Magnenat, Sandrine Morier, Christophe Menu, Philippe Bertschy, François R. Herrmann, Panteleimon Giannakopoulos

“…For risk, both a numeric scale and a structured professional judgement approach equally showed significant improvement over time. …”
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Clinicopathological and imaging features of struma ovarii: a retrospective study by Mei Chen, Shusheng Liao, Youfeng Xu, Xianwang Ye, Xiupeng Jia, Shengmin Zhang

“…The cystic wall and septation showed equal enhancement and slow regression. Two patients showed low enhancement in the protrusion and with slow regression. …”
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Exploring gender disparities: a survey among orthopedic residents by Rossella Ravaglia, Vittoria Mazzola, Paolo Ferrua, Luca La Verde, Matteo Formica, Pietro Simone Randelli

“…Although training opportunities appear to be equally distributed, the reported gender disparities seem to arise from subjective perceptions and cultural attitudes rather than measurable differences. …”
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Comparison of microcurrent and low level laser therapy on matrix metalloproteinases and tissue inhibitors of metalloproteinases expressions in surgical wound healing by Ayman Mohammed El Makakey, Mohammed H. Hassan, Nehad A. Abo-zaid, Bakheet E. M. Elsadek, Mahmoud A. Hifny, Radwa Mahmoud Elsharaby, Mohammed E. Ali

“…Abstract Purpose The purpose of this study was to compare the modulation effects of Microcurrent Therapy (MT) and Low-Level Laser Therapy (LLLT) on Matrix Metalloproteinases (MMPs) and tissue inhibitors of Metalloproteinases (TIMPs) expressions during healing of surgical wounds using appendectomy wound as a model. Methods Ninety patients who recently underwent appendectomy were randomly divided into 3 main groups of equal numbers. …”
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