The Temporal Changes in Ankle Joint Pathology, Pain and Secondary Osteoporosis in Collagen-Induced Arthritis Rats by Liu Q, Nan N, Li W, Dong M, Pu W, Liu Y, Zhao J, Hao H

“…Pain is the most important symptom of RA, and some patients with well-controlled inflammation may still experience pain.Purpose: To explore the relationship and dynamic changes between synovial inflammation and pain and bone destruction in collagen-induced arthritis (CIA) model rats, and to choose a better time window for drug treatment.Methods: The CIA model rats were constructed for 1, 2, 3, and 4-week groups. …”
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Comparative long-term efficacy of short-term spinal cord stimulation versus bipolar pulsed radiofrequency for refractory postherpetic neuralgia: a 24 month prospective study by Yun Li, Junnan Wang, Yang Chen, Feng Qiu, Tao Sun, Xuli Zhao

“…This study compares the long-term efficacy and safety of short-term spinal cord stimulation (stSCS) versus bipolar pulsed radiofrequency (bPRF) in managing refractory PHN. Methods In this prospective, controlled observational study, 140 PHN patients (aged ≥ 18 years; PHN duration ≥ 3 months) with inadequate pain relief from standard therapies were enrolled and randomized equally into two groups (n = 70 each). …”
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Mendelian Randomization Analysis Supports a Causal Relationship Between Circulating Inflammatory Proteins and Basal Cell Carcinoma by Fu ZD, Wang Y, Yan HL, Wu JH

“…Zhi-da Fu,1,2,* Yao Wang,3,* Hong-li Yan,2 Jian-hua Wu1 1Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Center for Reproductive Medicine, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 3Shanghai International Travel Healthcare Center, Shanghai Customs District, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-hua Wu, Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China, Email wujh_chyy@163.com Hong-li Yan, Center for Reproductive Medicine, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China, Email hongliyan@smmu.edu.cnBackground: It has been shown that the Basal cell carcinoma (BCC) is associated with chronic inflammation of skin conditions, the circulating inflammatory protein levels may be a more intuitive index in response to inflammation, however, the cause-and-effect relationship between circulating inflammatory proteins and BCC is currently unknown.Methods: This study performed a Mendelian randomization (MR) analysis using the plasma inflammatory protein levels from a large genome-wide protein quantitative trait loci study as the exposure data, and the outcome data from a GWAS for BCC. …”
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Molecular Characteristics and Antimicrobial Resistance of Linezolid-Resistant Staphylococcus aureus in Osteoarticular Infections: A 11-Year Study From a Hospital in Xi’an by Zhou S, Zhou K, Yang P, Kong M, Liu H, Zhang R, Hou Z, Liu J

“…Shan Zhou,1,* Ke Zhou,1,* Peihong Yang,1,* Meijuan Kong,1 Hao Liu,1 Rui Zhang,1 Zheng Hou,2 Jiayun Liu1 1Department of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi’an, Shanxi, 710032, People’s Republic of China; 2Institute of Medical Research, Northwestern Polytechnical University, Xi’an, Shanxi, 710129, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiayun Liu, Email jiayun@fmmu.edu.cn Zheng Hou, Email houzheng@nwpu.edu.cn; hzh_0001@163.comPurpose: This study examines the distribution of pathogens and the characteristics of linezolid-resistant Staphylococcus aureus (LRSA) in osteoarticular infections (OAIs) over an 11-year period.Methods: Identification and initial antimicrobial susceptibility testing were conducted using the VITEK2 compact system. …”
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The Value of Common Laboratory Markers in Predicting the Severity of COVID-19 Patients by Chen L, Jiang YH, Li MY, Huang B, Yuan L, Wan JH, Qin TY, Zeng TT, Chen QG

“…Lian Chen,1,* Yu-Huan Jiang,2,* Mei-Yong Li,3 Bo Huang,3 Lei Yuan,2 Jin-Hua Wan,2 Ting-Yu Qin,2 Ting-Ting Zeng,2 Qing-Gen Chen2 1Department of Ultrasound Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 3Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China*These authors contributed equally to this studyCorrespondence: Qing-Gen Chen, Department of Clinical Laboratory, the First Affiliated Hospital of Nanchang University, Nanchang, 330006, People’s Republic of China, Tel/Fax +86 0791-86319420, Email 272880243@qq.comPurpose: The aim of the present study was to identify more effective laboratory markers to assess the severity of corona virus disease 2019 and predict the progression of the disease by collecting more laboratory markers and variables.Patients and Methods: In this study, most risk factors, including epidemiological characteristics, blood cell counts, cytokines, and infection markers, were collected from 126 patients with COVID-19 to assess their predictive value.Results: The area under curve (AUC) of Albumin (Alb) to fibrinogen (Fib) ratio (AFR) (0.791), Lactate dehydrogenase (LDH) (0.792), myoglobin (MYO) (0.795), C-reactive protein (CRP) (0.801) and lymphocyte count (0.859) were higher than other markers to distinguish severe from non-severe patients in receiver operating characteristic (ROC) analysis. …”
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Mexiletine in the Treatment of LQT2, LQT3, and Acquired LQTS: A Meta-Analysis by Dhiya Ihsan, Mohammad Iqbal, Charlotte Johanna Cool, Chaerul Achmad, Miftah Pramudyo, Hawani Sasmaya Prameswari, Mohammad Rizki Akbar

“…Methods: A meta-analysis was conducted using systematic electronic searches of PubMed, Embase, and Cochrane Library. …”
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The Impact of Abusive Supervision on Nurses’ Organizational Silence: The Multiple Linear Mediation of Psychological Capital and Fear by Liang Y, Zhang Y, Feng Y, Huang Y, Zhang C

“…In this case, abusive management may occur.Methods: A cross-sectional survey design was employed. …”
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Patterns of prescription antihypertensive drug utilization and adherence to treatment guidelines in the city of Novi Sad by Tomas Ana, Tomić Zdenko, Milijašević Boris, Ban Milica, Horvat Olga, Vukmirović Saša, Sabo Ana

“…The use of more expensive ACEi was observed, despite the guidelines deeming all the drugs of these class equally effective in treatment of hypertension. …”
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Impact of 30-minute and 90-minute Naps on Aerobic and Anaerobic Intermittent Performance in Collegiate Soccer Players by Xu A, Wang N, Gao Y, Li X

“…Anran Xu,1,* Ning Wang,1,* Yang Gao,1 Xiaotian Li1,2 1Department of Physical Education and Research, Central South University, Changsha, 410083, People’s Republic of China; 2School of Sports Training, Wuhan Sport University, Wuhan, 430079, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yang Gao, Department of Physical Education and Research, Central South University, Changsha, 410083, People’s Republic of China, Email 1062065203@qq.com Xiaotian Li, Department of Physical Education and Research, Central South University, Changsha, 410083, People’s Republic of China, Email xiaotianli@csu.edu.cnPurpose: This study aims to investigate the effects of 30-minute and 90-minute naps on collegiate soccer players’ aerobic and anaerobic performance following a normal night of sleep, and to compare the performance differences between the two nap durations.Patients and Methods: A total of 25 male collegiate soccer players (age: 20 ± 1 years, height: 180.4 ± 5.6 cm, weight: 72.1 ± 4.2 kg, BMI: 22.1 ± 2.2 kg·m⁻²) participated in the RAST and 30– 15. …”
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Comparison between surgical outcome of bilateral recession and unilateral recession-resection in intermittent exotropia by Sheren M Aboshanab, Mohamed Y Saif, Elsayed M El Toukhi, Ahmed T. Gouda

“…The patients were randomly divided into two equal groups: BLR group and R&R group, each of 26 patients. …”
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Antibiofilm and Anticancer Activity of Multi-Walled Carbon Nanotubes Fabricated with Hot-Melt Extruded Astaxanthin-Mediated Synthesized Silver Nanoparticles by You HS, Jang YS, Sathiyaseelan A, Ryu SJ, Lee HY, Baek JS

“…The antibiofilm and anticancer effects were studied comprehensively by loading the AST AgNPs onto MWCNT-Silica.Methods: AgNPs-loaded MWCNT-silica (MWCNT-Ag) was prepared through the binding reaction of TSD and silanol groups and the aggregation interaction of Ag and TSD. …”
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Ultrasound guided thoracic dorsal root ganglia pulsed radiofrequency verified by fluroscopy for patients with lung cancer and metastatic thoracic cage pain: a randomized controlled... by Dina Kamel Abdel Maksoud, Sahar Ahmed El Karadway, Nagwa Ahmed Ibrahim, Dina Nabil Abbbas

“…The current study aimed to investigate the effect of ultrasound guided pulsed radiofrequency (PRF) of thoracic DRG on metastatic thoracic cage pain intensity and impact of pain on daily life of patients with lung cancer.Materials and Methods 30 patients with lung cancer thoracic cage metastatic pain were randomized equally to receive active PRF plus 0.5 ml lidocaine 2% for each thoracic DRG modulation (group 1) or non-active PRF plus 0.5 ml of lidocaine 2% (group 2). …”
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Evaluation of comparative efficacy of Celastrus paniculatus (Jyotishmati) capsule versus sertraline capsule in the management of Chittodvega (generalized anxiety disorder): protoco... by Sadhana Misar, Mayank Rai, Reeya Gamne

“…Aim and objectives To evaluate the comparative efficacy of Jyotishmati versus sertraline in the management of Chittodvega. Methods In this randomized active controlled double blind equivalence trial a total of 70 patients will be enrolled and divided into two equal groups. …”
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EPIDEMIOLOGICAL ANALYSIS OF CARIES IN CHILDREN DURING OUT-PATIENT TREATMENT IN DONETSK REGION by A. V. Makhniova

“…The purpose of this work is an epidemiological analysis of caries in children during out-patient treatment at the dentist`s in Donetsk region. Material and methods. The data of 33 697 children of three age groups were analyzed. …”
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Support and Its Effect for Persons Affected by COPD and Their Next of Kin - an Systematic Integrative Review by Johansson H, Jonasson LL, Berterö C

“…The result was analyzed with a constant comparison method.Results: Persons with COPD receive support from their next of kin, practically and emotionally. …”
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Unveiling Ventilator-Associated Pneumonia: S100A8 as a Promising Biomarker Through Integrated RNA-Seq Analysis by Wang Q, Dong J, Jing X, Long Y, Jia H, Li Y, Wang J

“…There was an urgent need for new diagnostic biomarkers for VAP.Methods: The transcriptome of VAP patients was analyzed and computed using bioinformatics techniques in this study. …”
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The Impact of Needle-Directed Thrombolysis in Thrombosed Arteriovenous Fistulas on Angioplasty Efficacy and the Prognostic Factors Associated with Success by Zhou Y, Lyu Q, Lai Q, Gao X, Chen L, Zhang X, Wan Z

“…Yu Zhou,1,* Qiong Lyu,2,* Qiquan Lai,1 Xuejing Gao,1 Ling Chen,1 Xi Zhang,1 Ziming Wan1 1Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of General Practice, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ziming Wan, Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Chongqing, 400016, People’s Republic of China, Tel +86-18696635322, Email wanziming001@163.comPurpose: Urokinase thrombolysis is a feasible method for salvage of thrombosed arteriovenous fistulas (AVFs). …”
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Plasma Fetuin-B Levels are Associated with Nervous Symptoms and Conduction Velocity in Patients with Painful DPN by Lin K, Wang X, Gu T, Feng K, Zeng W, Yang L

“…Ke Lin,1,* Xiaocui Wang,2,* Tao Gu,3,* Keduo Feng,1 Wang Zeng,1 Liu Yang1 1Department of Neurology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing, People’s Republic of China; 2Department of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, Second Affiliated Hospital of Army Medical University, Chongqing, People’s Republic of China; 3Department of Radiology, Second Affiliated Hospital of Army Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ke Lin; Liu Yang, Department of Neurology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing, People’s Republic of China, Email ayalinke@126.com; 510586640@qq.comAim: To assess the plasma concentrations of the novel hepatokine fetuin-B in individuals with type 2 diabetes with or without diabetic peripheral neuropathy (DPN), and to evaluate the relationship among fetuin-B levels, nervous function, and metabolic parameters.Methods: A total of 333 participants were recruited and divided into three groups: DPN, painful DPN (pDPN), and non-DPN. …”
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Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation by Zhou Y, Lou C, Xu X, Feng B, Fan X, Wang X

“…Yijing Zhou,* Chengli Lou,* Xiuqin Xu, Bo Feng, Xiaoping Fan, Xiangjing Wang Department of Nephropathy, Jiaxing Traditional Chinese Medicine Hospital, Jiaxing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yijing Zhou, Email zyj13967332522@163.comPurpose: Ursolic acid (UA) improves diabetic nephropathy (DN), but its regulatory mechanism requires further verification.Methods: The bioactive component-target network of UA in DN was determined using a network pharmacology approach. …”
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Ultrasound-guided pulsed radiofrequency versus perineural platelet rich plasma injection for the treatment of idiopathic carpal tunnel syndrome: a prospective randomized controlled... by Engi Yousry Hashem, Faten Saeed Shamandy, Ahmed Fawzy Elmulla, Magdy AbdelAziz Mansour

“…The secondary outcomes included functional outcome evaluated by the Boston Carpal Tunnel Questionnaire (BCTQ), Nerve Conduction Velocity (NCV) and median nerve cross-sectional area (CSA). Methods This prospective, double-blinded, randomized controlled study was conducted on Seventy-five patients diagnosed with mild to moderate CTS, they were randomly allocated into three equal groups. …”
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