Long-Term Administration of Anthraquinone Rhein on Induction of Constipation in Sprague-Dawley Rats via SCF/c-Kit Signaling Pathways by Bo Zhang, Mingdong Huo, Zhicheng Chen, Feng Gao, Yan Liu, Xingxin Zhou

“…Herein, we aimed to investigate the long-term stimulation of rhein on induction of constipation in rats and its underlying mechanisms. Materials and Methods. After establishing rat models of constipation, the rats were randomly divided into two equal subgroups and administered daily with normal saline (model control group) or 10 ml/kg PEG4,000 (PEG-treated group). …”
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Profile of the geriatric patient hospitalised at Universitas Hospital, South Africa by Anna M. van Staden, Dirk J.V. Weich

“…The majority of the patients were single and an equal amount were living in old age homes and with their families. …”
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Preoperative chronic opiate use associated with a worse joint-specific function and quality of life before and after total hip and knee arthroplasty by Eliott S. Martinson, Nick D. Clement, Deborah J. MacDonald, Chloe E. H. Scott, Colin R. Howie

“…However, patients were equally satisfied with outcomes. Cite this article: Bone Jt Open 2025;6(4):405–412.…”
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Novel Obstetric Air Cushion for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section: A Randomized Controlled Clinical Trial by Dong Y, Cao WW, Weng H, Liu R, Huang DD

“…We assessed the effect of a novel obstetric air cushion pretreatment on the incidence of hypotension after spinal anesthesia.Patients and Methods: Eighty parturients were randomly assigned to the air cushion or blank control group (Group A or B, respectively). …”
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Prognostic Value of the Triglyceride-Glucose Index Combined with Non-HDL-C/HDL-C Ratio for Predicting Coronary Microvascular Dysfunction in ACS Patients Post-PCI by Hang S, Tang N, Li K, Zhang Q, Hao J, Zhang Y, Qi C

“…This study aimed to evaluate the combined predictive value of the triglyceride-glucose index (TyG) and non-HDL-C/HDL-C ratio (NHHR) for CMD in ACS patients post-PCI.Methods: A retrospective analysis of 542 ACS patients undergoing PCI (2021– 2023) was conducted. …”
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A Flow Cytometric Approach to Assess RBC-Bound IgG Antibodies in Different Age Populations by Anwar Ullah, Lina Liu, Xia Qi, Hui Liu

“…After incubation, antihuman globulin (AHG) was added and checked for the index of agglutination (IAG) using flow cytometry method. A control sample was also analyzed using the same method. …”
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Impact of root canal shaping using TruNatomy on postoperative pain and operative torque generation: a randomized clinical trial by Tarek Ali Al-Mosalmy, Heba Maged El-Far, Madiha Mahmoud Gomaa, Dina Ahmed Morsy

“…Aim To compare the effect of canal shaping using TruNatomy (TN) rotary system to RaCe (RC) rotary system on post-operative pain in necrotic maxillary bi-rooted premolars, while simultaneously inspecting the real-time dynamic forces produced during instrumentation. Methods In this parallel group superiority trial, following power calculation, 40 patients diagnosed with pulp necrosis in asymptomatic bi-rooted maxillary premolars were recruited and randomly allocated into two equal groups (n = 20) according to the instrumentation system used. …”
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Axial Ligand Effects on the Mechanism of Ru-CO Bond Photodissociation and Photophysical Properties of Ru(II)-Salen PhotoCORMs/Theranostics: A Density Functional Theory Study by Niq Catevas, Athanassios Tsipis

“…The Ru-CO bonding properties were scrutinized using Natural Bond Orbital (NBO), Natural Energy Decomposition Analysis (NEDA) and Natural Orbital of Chemical Valence (NOCV) methods. The nature of the Ru-CO bond is composite, i.e., electrostatic, covalent and charge transfer. …”
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Teacher in the situation of setting a learning task by E.V. Chudinova

“…The condition for the emergence of cumulative action in solving a learning task is a special authorial position of the teacher. <strong>Methods and materials.</strong> Five teachers (women from 28 to 54 years old, experience in the D.B. …”
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The Probiotic Effects of Lactobacillus brevis CD2 on Caries Related Variables of Dental Plaque Biofilm by Guglielmo Campus, Maria Grazia Cagetti, Anna Lehrkinder, Ali Alshabeeb, Nicole Caimoni, Peter Lingström

“…Plaque acidogenicity was assessed using the microtouch method after a 10 ml mouth rinse containing 10% sucrose for 1 minute (on day 0 and day 28). …”
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PANoptosis-Relevant Subgroups Predicts Prognosis and Characterizes the Tumour Microenvironment in Ovarian Cancer by Chen Y, Deng Z, Chen J, Lin J, Zou J, Li S, Sun Y

“…However, its prognostic relevance in OC remains unclear.Methods: Utilizing data from The Cancer Genome Atlas (TCGA), we analyzed transcriptomic and clinical signatures of OC patients. …”
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Health Literacy, Label Comprehension, and Consumer Perceptions of Quasi-Drug Information Among Korean Adults: A Cross-Sectional Study by Ko Y, Kim HJ, Lee SM

“…This study aimed to evaluate HL and its impact on comprehending quasi-drug labels, assess consumer perceptions of key label elements and their perceived importance, and provide actionable recommendations for improving label design and health communication.Methods: An online cross-sectional survey of 500 Korean adults (aged 20– 69) was conducted in September 2023 using proportionate stratified sampling based on the 2020 Korean Census. …”
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Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients by Chen Y, Zhang ZJ, Zhang XF, Peng Y, Jiao Z, Wu JX

“…Yueting Chen,1,&amp;ast; Zuo-Jing Zhang,2,&amp;ast; Xiao-Feng Zhang,2 Yuan Peng,2 Zheng Jiao,1,&amp;ast; Jing-Xiang Wu2,&amp;ast; 1Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Zheng Jiao, Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, People’s Republic of China, Email jiaozhen@online.sh.cn Jing-Xiang Wu, Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui District, Shanghai, 200030, People’s Republic of China, Tel +86 021-22200000-3302, Fax +86 021-32260806, Email wjx1132@163.comPurpose: This study aimed to characterize the pharmacokinetics/pharmacodynamics (PK/PD) of remimazolam in patients under general anesthesia using a population analysis and to develop a web-based dashboard tool that directly displays the optimal dosing regimen for general anesthesia.Patients and Methods: A total of 20 patients received remimazolam for general anesthesia, during which intensive arterial blood samples and bispectral index (BIS) values were collected. …”
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A randomised trial to compare the safety, tolerability and efficacy of three drug combinations for intermittent preventive treatment in children. by Kalifa Bojang, Francis Akor, Ousman Bittaye, David Conway, Christian Bottomley, Paul Milligan, Brian Greenwood

“…Thus, we have investigated whether SP plus AQ, SP plus piperaquine (PQ) and dihydroartemisinin (DHA) plus PQ might be equally safe and effective when used for IPT in children in an area of seasonal transmission.…”
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Physical development and sociocultural context influences on children’s physical activity by Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David Stodden, Guilherme dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira de Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely

“…Health policies should encourage equal gender participation in culturally significant sports or activities of a particular region/country, specifically within the family context.…”
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Determination of administered activities for the treatment of Graves' disease with iodine-131: Proposition of a simplified dosimetric procedure by Idrissa Adamou Soli, Djibrillou Moussa Issoufou, Skander Rahabi, Ada Ali, Eric Adehossi, Salah Eddine Bouyoucef

“…Empirical determination of activity in the treatment of GD gives higher activities (1.5 times) to patients than dosimetric methods based on the determination of extrapolated effective half-life.…”
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Ixodidae tick-borne infections in kemerovo region and in novokuznetsk by Z. A. Khokhlova, R. A. Gileva, T. V. Sereda, Z. A. Klinova, N. S. Kolobova, A. I. Osokina

“…To analyse the epidemiological situation on the ixodidae tick-borne infections in Kemerovo Region and to determine their clinical and epidemiological peculiarities in Novokuznetsk.The materials and methods. There have been analysed the official statistical data on the tick-borne infections, morbidity in the course of 10 years. …”
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Increased Stress Hyperglycemia Ratio Predicts Poor Clinical Outcome in Critically Ill COPD Patients: A Retrospective Study by Qiao M, Yang H, Qin M, Li Y, Wang H

“…The present study aimed to investigate the relationship between SHR and adverse clinical outcomes in critically ill COPD patients.Methods: A total of 1,580 patients diagnosed with COPD were included in this retrospective cohort study. …”
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Awareness, Beliefs, and Psychological Impact of Patients with Alopecia Areata in Saudi Arabia: A Multi-Center Study by Almulhim NA, Alojail HY, Aljughayman MA, Almarri FH, Alsultan NH, Albash LA, Almukhaimar SK, Alkhamis AA, Albaqshi MA, Alkhawajah AA

“…This study aims to assess the awareness, beliefs, and psychological impact of patients with Alopecia Areata.Patients and Methods: This cross-sectional study was conducted in Eastern and Central provinces of Saudi Arabia and utilized online questionnaires to evaluate knowledge, beliefs, and psychological effects of patients with Alopecia Areata. …”
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OBJECTIVE ACCOMMODATION RESPONSE VALUE (COMPLETENESS OF CYCLOPLEGIA) AFTER DIAGNOSTIC INSTILLATIONS OF DIVERSE MEDICATIONS by N. A. Tarasova, E. P. Tarutta, G. A. Markosian, M. V. Maksimova

“…Purpose: to compare the extent of cycloplegia by residual accommodation response after instillations of various medications. Materials and methods. 54 patients, aged 8 to 23, with varied degrees of myopia were instilled twice, with an interval of 10 minutes, with one of the following medications: Cyclopentolate 1 %, Tropicamide 1 %, Midrimax, and Phenylephrine 2.5 %. …”
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