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6041
Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer’s Disease
Published 2025-01-01“…The primary goal of this study was to investigate the link between KI and AD, with a specific focus on identifying diagnostic biomarkers for KI-related AD.Methods: The first step of the present study was to use Mendelian randomization (MR) analysis to investigate the link between KI and AD, followed by verification of in vivo and in vitro experiments. …”
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6042
Eating disorders in relation to alcohol addiction—A study of drunkorexia in young adults in Poland
Published 2025-07-01“…IntroductionThe aim of the study was to determine the frequency of eating disorders occurring in combination with alcohol dependence in young adults in Poland.Material and methodsThe study was conducted in Poland between 1st July 2023 and 31st July 2024. …”
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6043
Trends and factors associated with immediate postnatal care utilisation in Ethiopia: analysis of the demographic and health surveys, 2011-2019
Published 2023-06-01“…Having less than four (adjusted OR (aOR)=3.33; 95% CI=1.77-6.24) and greater than and equal to four antenatal care visits (aOR=7.19; 95% CI=3.80-13.56), and caesarean delivery (aOR=4.39; 95% CI=2.28-8.46) were factors positively associated with immediate postnatal care utilisation. …”
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6044
Addressing the Сompetence of Experts and Specialists in the Light of Provisions of ISO/IEC 17025:2017 and International Experience in Applying Specialized Knowledge
Published 2019-10-01“…A situation when there is equality of knowledge and/or skills and personal qualities can be adapted (to some extent and without significant adjustments) to the Russian realities in forensic activities. …”
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6045
Informant accuracy of IQCODE, AD8 and GPCOGi for diagnosis of dementia: does your friend know best?
Published 2025-04-01“…A threshold of greater than 3.3 on IQCODE, greater or equal to 2 on AD8 and less than 5 on the informant component of GPCOG was used to indicate an abnormal test. …”
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6046
Serum glutathione reductase level as a disease activity biomarker in systemic lupus erythematosus: a single-centre preliminary study
Published 2025-06-01“…Objectives This study aimed to investigate serum glutathione reductase (GR) levels in patients with SLE and to assess its association with disease activity.Methods The retrospective study collected clinical data, including serum GR, complement (C) 3 and C4 levels, among patients with SLE. …”
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6047
Suboptimal Immune Reconstitution among HIV-Infected Saudi Patients following Successful Antiretroviral Treatment
Published 2019-01-01“…The inclusion criterion was patients with CD4 reconstitution of either equal to or more than 400 cells/mm3 with an undetectable HIV viral load following ART. …”
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6048
Pituitary-Thyroid Hormones and Related Indices in Euthyroid Type 2 Diabetes: Association With Thyroid Nodules
Published 2025-02-01“…We aimed to explore the correlates of TNs in euthyroid type 2 diabetes (T2D) patients.Methods: This cross-sectional study included 1965 euthyroid adults with T2D. …”
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6049
Maternal dietary diversity and associated factors with a focus on the food environment in the Tigray region, Northern Ethiopia
Published 2025-08-01“…The maternal diet diversity score was defined as adequate if it was greater than or equal to five food groups. Bivariate and multivariable binary logistic regressions were used to analyze the data. …”
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6050
The Efficacy of CT-Guided Pulsed Radiofrequency of the Dorsal Root Ganglion Combined with Methylene Blue Sympathetic Injection on Herpes-Zoster Neuralgia: A Retrospective Study
Published 2025-07-01“…This is the first report for thoracic or lumbar sympathetic nerve MB injection.Materials and Methods: 64 patients in study were divided into two groups: PRF combined with sympathetic nerves MB injection group (group A; n = 32,); PRF group (group B; n = 32). …”
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6051
Articaine Needle - Free Anesthesia Vs Conventional Anesthesia in Root Canal Treatment of Irreversible Pulpitis in Permanent Teeth: A Prospective Study on Anesthetic Efficacy and Ef...
Published 2025-04-01“…Suhui Qian,1,* Ziying Meng,2,* Haiyan Zhang,1 Kaicheng Li,1 Fei Zhang,1 Sen Zhang,1 Jianfei Liu,1 Zhou Zhou1 1Department of Stomatology, Huaibei People’s Hospital, Huaibei, Anhui, People’s Republic of China; 2Stomatology Department of Suixi County Hospital, Huaibei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhou Zhou, Email Zz178685@163.comObjective: This study aimed to compare the anesthetic efficacy of articaine needle-free anesthesia with conventional lidocaine nerve block anesthesia for root canal treatment in permanent teeth with irreversible pulpitis.Methods: In this prospective clinical trial, 94 patients were randomly allocated to receive either articaine needle-free anesthesia (n=47) or lidocaine nerve block anesthesia (n=47). …”
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6052
The impact of pulmonary hypertension on the risk of early graft dysfunction in related kidney transplantation
Published 2024-09-01“…To study the prevalence of pulmonary hypertension among patients with end-stage renal disease and to determine its impact on the development of early renal graft dysfunction.Material and methods. The study was based on the analysis of treatment results in 650 patients who underwent kidney transplantation from a living related donor. …”
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6053
Efficient system design of capacitive coupling wireless charging for low-power applications
Published 2025-05-01“…The methods used include LCLC and LCL compensation topologies resonate with the capacitive coupler and deliver high voltage to the charging pads. …”
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6054
FAM105B Promotes Hepatocellular Carcinoma Progression and Metastasis by Activating the PI3K/AKT/MTOR Signaling Pathway and Inducing Epithelial-Mesenchymal Transition
Published 2025-07-01“…However, its role in HCC is not well understood.Methods: FAM105B expression in HCC patients was validated using public clinical datasets. …”
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6055
Amelioration of Inflammation and Metabolic Blockage in GALC Deficient Mice After Enzyme Replacement Therapy via Extracellular Vesicles
Published 2025-07-01“…Early intervention is critical to mitigate disease progression and limit neurological injury.Methods: To assess the therapeutic potential of early enzyme replacement therapy (ERT), HeLa cells were genetically engineered to overexpress GALC, and extracellular vesicles (EVs) containing GALC were isolated. …”
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6056
Anti-Inflammatory Regulatory Role of Signal Transducer and Activator of Transcription 3 Phosphorylation in Regulating Hypersensitivity Responses to Echinococcus granulosus Hydatid...
Published 2025-04-01“…Shan-Shan Li,1,2,* Jing-Ru Zhou,3,* Chun-Sheng Wang,1,2 Jia-Ling Wang,1 Yu-Qian Li,1,2 Xilizati Kulaixi,1 Li-Wei Cao,1,2 Bayina Batesurong,1,2 Jian-Rong Ye1 1Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China; 2The First Clinical Medical College of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China; 3Department of Anesthesiology, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830063, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Rong Ye, Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, No. 137, Liyushan South Road, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China, Tel +86 18999938777, Email ywjianrongym@126.comObjective: This study aims to investigate the anti-inflammatory regulatory function of signal transducer and activator of transcription 3 (STAT3) phosphorylation in hypersensitivity responses triggered by Echinococcus granulosus hydatid cyst fluid through in vitro RBL-2H3 cell culture.Methods: RBL-2H3 cells were cultured in vitro and sensitized with immunoglobulin E (IgE), followed by intervention with STAT3 inhibitors Stattic and JSI-124. …”
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6057
Prescription of essential medication during the final hospitalization of patients with heart failure or cancer
Published 2025-02-01“…However, it is not known whether their usage is equally common for patients with other chronic and progressive conditions, such as heart failure (HF), or for those who are not under specialized palliative care (PC-). …”
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6058
Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients
Published 2019-09-01“…The peptic ulcer of the stomach, duodenum and “other diseases of the digestive system” (8.8 % and 7.7 %, respectively) are represented in almost equal shares. In the etiological structure of liver cirrhosis, viral (39 %) and alcoholic (36 %) liver diseases are leading. …”
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6059
Elucidating Molecule-Crosstalk of Neutrophil Extracellular Traps Between Cardiovascular Disease and Psoriasis: Insights Into Mendelian Randomization, Single-Cell RNA Analysis, Shar...
Published 2025-03-01“…Neutrophil extracellular traps (NETs) are implicated in both conditions, but the mechanisms remain unclear.Methods: We integrated bulk and single-cell RNA sequencing, mendelian randomization, immune microenvironment analysis, and molecular docking to explore the molecular interactions between LVH and PSO, focusing on NET-related pathways. …”
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6060
Impact of preoperative mild cognitive impairment on cerebrovascular events and cognitive status in patients undergoing coronary artery bypass grafting: data from 5-year follow-up
Published 2021-10-01“…Neurodynamic disorders occurred equally frequently in both groups (63,8% and 57,8% of patients, respectively). …”
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