Effectiveness and Efficiency Comparison of One-Day vs Eight-Day Methotrexate Protocols in Managing Low-Risk Gestational Trophoblastic Neoplasia by Agbari V, Hidayat YM, Kurniadi A, Salima S, Harsono AB, Suardi D, Yuseran H, Lisnasari D

“…The 8-day Methotrexate (MTX) 50 mg protocol has been implemented at our center; however, due to limitation of government insurance, this study aims to compare its effectiveness against the 1-day Methotrexate (MTX) 300 mg/m² protocol.Methods: A retrospective cohort study compared two protocols for low-risk GTN treatment at Dr. …”
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Comparison of Second-Trimester Uterine Artery Doppler Indices between Pregnant Women with and without Prior Cesarean Delivery and Effect on Perinatal Outcomes by Bundaree Chaiprasit, Suthasinee Mataneedol, Buppa Smanchat, Kornkarn Bhamarapravatana, Komsun Suwannarurk

“…Results: Total of 416 participants were recruited and divided equally. The mean age of participants was 30.5 years old. …”
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Assessment of the urinary uric acid-to-creatinine ratio as a diagnostic marker for perinatal asphyxia in a resource-poor setting: a case control study by Chukwunonso Chigozie Iheji, Isaac Nwabueze Asinobi, Ikenna Kingsley Ndu, Anthony Nnaemeka Ikefuna

“…In the study population, there were an equal number of asphyxiated and apparently healthy babies. …”
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Analgesic Quality Improvement in Paravertebral Blocks for Pediatric Nuss Procedure: An Exploratory Report on the Effects of Perineural Combined Glucocorticoids by Donham RN, Jin E, Caty MG, Thomas DA, Yuan C, Hollingsworth K, Zhang X, Yanez ND, Li J

“…Rebecca N Donham,1,* Evan Jin,2,* Michael G Caty,3 Donna-Ann Thomas,2 Claire Yuan,4 Kamren Hollingsworth,2 Xuewei Zhang,2 N David Yanez,5 Jinlei Li2,* 1Alabama College of Osteopathic Medicine, Dothan, AL, USA; 2Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA; 3Department of Surgery, Yale University School of Medicine, New Haven, CT, USA; 4Harvard University, Cambridge, MA, USA; 5Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA*These authors contributed equally to this workCorrespondence: Jinlei Li, Department of Anesthesiology, Yale University School of Medicine, 20 York Street, New Haven, CT, 06510, USA, Tel +1 (475) 434-4038, Email jinlei.li@yale.eduPurpose: Pectus excavatum repair using the Nuss procedure is associated with significant postoperative opioid consumption even in the presence of a continuous thoracic paravertebral block.Patients and Methods: A CQI project was initiated by adding combined glucocorticoids as perineural adjuvants to continuous thoracic paravertebral block. …”
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The Anti-Inflammatory Effect of Chenopodium Murale in Comparison to Salvia Frigida on Atopic Eczema by Zahraa Y. Hassan, Tuka Y. Hassan, Ahmed Y. Kanany

“…Fifty mice were included in the study, subdivided equally into five subgroups [control, induction, Tacrolimus-1%, Phytosterol-3%, and Phenolic-5%]. …”
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Health‐related quality of life in adult‐type ovarian granulosa cell tumor survivors by Ulla‐Maija Haltia, Saku Torvinen, Saara Bryk, Harri Sintonen, Johanna Tapper

“…The objective of our study was to assess health‐related quality of life (HRQoL) in AGCT survivors. Material and Methods 15D and European Organization for Research and Treatment of Cancer (EORTC‐QLQ‐C30) questionnaires were collected from our prospective AGCT patient cohort, consisting of 171 AGCT survivors. …”
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Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery by Roberto Visentin, Katrine Brodersen, Bjørn Richelsen, Niels Møller, Chiara Dalla Man, Andreas Kristian Pedersen, Jan Abrahamsen, Jens Juul Holst, Michael Festersen Nielsen

“…Two months after surgery, insulin secretion (p<0.05) and glucose effectiveness both improved equally in the two groups (11%, RYGB (p<0.01); 8%, SG (p>0.05)), whereas insulin sensitivity remained virtually unaltered. …”
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Gender-related differences in care-seeking behaviour for newborns: a systematic review of the evidence in South Asia by Sharif A. Ismail, Amy McCullough, Sufang Guo, Alyssa Sharkey, Sheeba Harma, Paul Rutter

“…We reviewed evidence on sex and gender differences in care-seeking behaviour for neonates as a driver for this.Methods We conducted a systematic review of literature published between January 1st, 1996 and August 31st, 2016 in Pubmed, Embase, Eldis and Imsear databases, supplemented by grey literature searches. …”
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Exploring spousal disparities: Age, earnings, and education as predictors of intimate partner violence in 29 developing countries by Rafi Amir-ud-Din, Rubina Idrees, Javaria Farooqui, Abdus Sattar Abbasi

“…Conclusion: The findings underscore the need for targeted policies to prevent IPV, particularly in low- and middle-income countries, by addressing spousal disparities in age, earnings, and education to promote gender equality.…”
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Analysis of COL1A1_1 gene (rs1107946) polymorphism as a risk factor for low birth weight by T. Yе. Shumna, T. O. Levchuk, O. M. Kamyshnyi

“…Polymerase chain reaction genotyping method was used. Results. It was found that the frequency of the C allele detection was equal to 39.60 %, the A allele – 60.42 %, chi-square (df = 1) 29.17, P < 0.05. …”
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Cellular and molecular screening of connective tissue dysplasia in adolescent athletes (pilot study) by M. V. Dvornichenko, A. E. Sizikova, T. V. Saprina, E. N. Pashkova, M. S. Shcherbinko, I. A. Khlusov, V. V. Novitsky

“…The purpose of the study is to evaluate the cellular and molecular parameters of bone remodeling in the blood as potential markers of undifferentiated forms of connective tissue dysplasiaMaterials and methods. The structural and functional status of cellular elements of in vitro culturing of mononuclear leukocytes of peripheral blood in adolescent athletes connected with phenotypic manifestations of undifferentiated connective tissue dysplasia (UCTD) were investigated. 25 pupils of sport schools from 10–14 years old (main disciplines: figure skating, gymnastics, athletics) were examined with the help of express analysis. …”
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Altered Neuroplasticity in Epilepsy is Associated with Neuroinflammation and Oxidative Stress: In vivo Evidence of Brain-Derived Extracellular Vesicles by Wang S, Zhang H, Li R, Liu Z, Xiang D

“…While preclinical studies implicate neuroinflammation and oxidative stress in epilepsy-associated neuroplasticity, in vivo molecular-level evidence in humans is lacking.Patients and Methods: We used astrocyte-derived extracellular vesicles (ADEVs) and neuron-derived extracellular vesicles (NDEVs) as brain-derived biomarkers to explore biomarkers of neuroplasticity, neuroinflammation, and oxidative stress. …”
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Promising Response to Neoadjuvant Chemotherapy Plus Immunotherapy in Metaplastic Breast Carcinoma by Tan Q, Li N, Wang Y, Du T, Liang G, Zhao Z, Tang J, Wu H

“…This study aimed to evaluate the efficacy of combining NAC with immune checkpoint inhibitors (ICIs) in MpBC patients.Methods: We conducted a retrospective analysis of MpBC patients treated with NAC, with or without the addition of immunotherapy, at Sun Yat-sen university Cancer center between 2017 and 2024. …”
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First Experience in Small Incision Lenticule Extraction with the Femto LDV Z8 and Lenticule Evaluation Using Scanning Electron Microscopy by Mengmeng Wang, Fengju Zhang, Christine Carole Copruz, Longhui Han

“…To evaluate the specifications and technique properties of the new Femto LDV Z8 in creating intrastromal refractive lenticules during small incision lenticule extraction (SMILE). Methods. Six enucleated porcine eyeballs were equally divided into two groups (Femto LDV Z8 or VisuMax) and were randomly assigned to three experienced refractive surgeons who performed SMILE on each group. …”
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Demographic profile of pediatric malignancies in Himachal Pradesh by Anupam Badhan, Parveen Bhardwaj, Vijay Yadav, Neelam Grover, Rajeev Kumar Seem

“…Acute lymphoblastic leukemia was the most common hematological malignancy noted in 22.58%, followed equally by Hodgkin's disease and non-Hodgkin's lymphoma (20% of total hematological malignancies). …”
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Effects of bioactive peptides combined with probiotics on serum uric acid in patients with hyperuricemia by HAN Dan，ZHAO Ya，HUANG Enshan，YE Shuhua，WANG Wanjin，WU Fangmin，WANG Dingliang，ZHANG Ronghua

“…Objective: To evaluate the effect of bioactive peptides combined with probiotics on serum uric acid (SUA) in patients with hyperuricemia (HUA), so as to provide the evidence for prevention and treatment of HUA. Methods: The patients with HUA aged 18 to 65 years were selected and randomly divided into an intervention group and a control group. …”
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Diagnostics of Transmission Bearing Units Based on Thermal Load Study by A. G. Pastukhov, E. P. Timashov

“…To establish the functional relationship between the temperature in the friction zone and the diagnostic temperature, the method of finite element analysis is used under steady-state thermal conductivity conditions. …”
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Comparison of active tuberculosis occurrence associated with Janus kinase inhibitors and biological DMARDs in rheumatoid arthritis by Jin-Won Kwon, Yun-Kyoung Song, Jaehee Lee, Junwoo Jo

“…Patients without LTBI and using JAK inhibitors had a significantly lower risk of tuberculosis across all ages and sexes compared with bDMARD users.Conclusion Patients with RA using JAK inhibitors have a significantly lower risk of active tuberculosis than bDMARD users in South Korea; however, patients with RA having LTBI are equally at risk regardless of the treatment received (JAK inhibitor vs bDMARD). …”
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Depictions of older adults residing in nursing homes: a Goffman-inspired thematic analysis of children’s picture books in a Danish context by Stinne Glasdam, Ragnhild Julante Andersen Gulestø, Christie Stilwell

“…Older adult characters were often depicted as equals to children, while the middle generation functioned as a bridge between generations without much interaction with older adults. …”
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The influence of an interactive educational approach on advance care planning counseling in individuals with psychiatric disorders by Yi-Chien Chen, Fang-Ying Chu, Ling-Yu Chang, Ming-Yuan Hsieh, Chao-Hsien Lee

“…This research explores the influence of an interactive educational approach on the ACP process for psychiatric patients and whether this approach can enhance their comprehension, attitudes, and intentions regarding Advance Decisions (AD). Methods To accommodate potential variances and ensure robustness in our findings, we ultimately elected to recruit 90 participants. …”
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