Investigation of efficiency and quality of functioning of led lighting elements of electrical systems at the maximum permissible ambient temperature by R. H. Tukshaitov, N. V. Rozhencova, A. R. Denisova

“…It is shown that a filament LED lamp with 4 filaments, if it is operated for 4.5 hours a day in conditions of elevated ambient temperature, can work for almost more than one year. METHODS. The resource of filament and typical LED lamps of different power is considered in comparative terms when they are operated at a relatively high ambient temperature.RESULTS. …”
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Hepato-protective and repro-protective power of immulant (echinacea purpurea) against chlorpyrifos toxicity via apoptotic genes signaling pathway by Ahlam G. Khalifa, Fadwa A. Elroby, Asmaa K. Abdelghany

“…The study target is to evaluate the anti-apoptotic effect of IM against CPF toxicity. Methods Thirty-two adult male white albino rats were separated into four groups in equal (n = 8 rats per each) as follows: control group (C), chlorpyrifos group (CPF): rats administered CPF at a dose of 6.75 mg/kg b.wt, chlorpyrifos +immulant group (CPF + IM): rats orally gavaged CPF + IM at a dose of 6.75 mg/kg + 150 mg\kg b.wt, and immulant group (IM): rats given IM at a dose of 150 mg\kg b.wt. …”
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Validation of an AI-Powered Smart Dry Powder Inhaler (RS01X) for Asthma and COPD in a Clinical Setting by Chamaon D, Sportel E, Elferink ECM, van der Palen J

“…The objective was to validate the smart DPI compared to an external inhalation profile recorder (IPR).Methods: This monocenter cross-sectional study with 97 participants comprises patients with COPD, asthma and healthy participants. …”
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PREDICTIVE SIGNIFICANCE OF ARTERIAL STIFFNESS PARAMETERS IN EVALUATION OF CARDIOMETABOLIC RISK IN OBESITY PATIENTS by O. Yu. Druzhilova, M. A. Druzhilov, T. Yu. Kuznetsova

“…Bifunctional BP 24 hour monitoring with the arterial wall stiffness evaluation in obesity patients is more preferable method making for additional information gather for further risk stratification.…”
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Targeting AGE-RAGE Signaling Pathway with Hujin Decoction Ameliorates MAFLD in HepG2 Cells by Zhang Z, Shi J, Liu F, Zhou J, Shen Q, Shi X

“…Zixuan Zhang,1,* Jiaxi Shi,2,* Fuxuan Liu,1 Jing Zhou,1 Qi Shen,3 Xuguang Shi1 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, People’s Republic of China; 2The First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510405, People’s Republic of China; 3Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuguang Shi, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China, Tel +8613602740975, Email sxg6902@126.comPurpose: To explore the mechanism and substance basis of HJD for the treatment of MAFLD based on system pharmacology.Patients and Methods: The ingredients of HJD in vitro and in vivo were detected by UPLC-MS/MS, then network pharmacology and molecular docking technology were used to predict the mechanism and substance basis, then the establishment of in vitro MAFLD model was confirmed by oil red O staining and ELISA technology, and finally the mechanism was verified by PCR, WB and flow cell technology.Results: System pharmacology determined that succinic acid, Ginsenoside Rh4, Caffeic acid, 7-Methoxycoumarin, 5-Acetylsalicylic acid and other ingredients were the basis of pharmacodynamic substances, while RAGE[Advanced glycosylation end product-specific receptor (RAGE)], BCL2[Apoptosis regulator Bcl-2 (BCL2)], and CASP3[Caspase-3 (CASP3)] were predicted as the core targets, and AGE-RAGE was the key pathway. …”
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Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis by Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C

“…The aim of this study was to explore the pharmacological mechanism of Corilagin.Methods: This study utilized gas chromatography-mass spectrometry (GC-MS) to analyze central target tissues, comprehensively exploring the pharmacological mechanism of Corilagin in mouse models. …”
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Evaluation of Iron Overload Between Age Groups Using Magnetic Resonance Imaging and Its Correlation with Iron Profile in Transfusion-dependent Thalassemia by Pustika Amalia Wahidiyat, Stephen Diah Iskandar, Damayanti Sekarsari

“…The number of subjects between children and adults was almost equal. Most of subjects had normal cardiac iron deposition. …”
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Binary solvent extraction of intracellular lipids from Rhodotorula toruloides for cell recycling by Jingyi Song, Rasool Kamal, Yadong Chu, Shiyu Liang, Zongbao K. Zhao, Qitian Huang

“…Given the complexity of microbial cell walls and the demand for efficient and environmentally friendly extraction methods, further research is still needed in this area. …”
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A measure of the difference between test sets for generating controlled random tests by V. N. Yarmolik, V. V. Petrovskaya, I. Mrozek

“…The limitations of using the Hamming and Damerau – Levenshtein distances to obtain a measure of the difference between test sets are shown.Methods . Based on the characteristic of the interval used in the theory of the chain of successive events, a new measure of the difference between two symbolic test sets is determined. …”
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Analysis of Tumor and Tumor-Like Entities Tested on the Orthopaedic In-Training Examination From 2012 to 2023 by Sean Kelly, MD, Braden Goldberg, MD, Eli Bryk, MD, FAAOS, FAOA, FACS, Vincent Vigorita, MD

“…Tumor-related questions constituted 10–16% of each OITE, with an equal number of questions concerning benign and malignant entities. …”
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Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vas... by Sina Mahdavifard, Hamid Reza Malekzadeh

“…Therefore, we aimed to study the impact of the combination of thiamine and niacin on hepatic NF-kβ signaling, metabolic profile, and Glo-I activity in male rats with type-2 diabetes (T2DM).Materials and Methods: Forty male rats were divided equally into five groups: control, diabetic, diabetic treated with thiamine (180 mg/l in drinking water), niacin (180 mg/l), and a combination of both. …”
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Combining Supervised and Reinforcement Learning to Build a Generic Defensive Cyber Agent by Muhammad Omer Farooq, Thomas Kunz

“…Sophisticated mechanisms for attacking computer networks are emerging, making it crucial to have equally advanced mechanisms in place to defend against these malicious attacks. …”
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User experience with pregnancy tracker mobile apps: Findings from comment-based qualitative study. by Md Alamgir Hossain, Janet Perkins, Md Tanvir Hasan, Sharon Low Bee Lian, Ribica Chowdhury, Md Tanzirul Alam, Anisuddin Ahmed, Mohammad Sohel Shomik, Shams El Arifeen, Ahmed Ehsanur Rahman, Aniqa Tasnim Hossain, M Shafiqur Rahman

“…While most of the apps are user-friendly, not all of them are equally appealing. This study aimed to explore the user experience (UX) of pregnancy tracker mobile apps used by pregnant women.…”
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Periconception glycemic control and congenital anomalies in women with pregestational diabetes by Annie M Dude, Nevert Badreldin, Amanda Schieler, Lynn M Yee

“…Our study cohort is racially and ethnically diverse, with approximately equal numbers of women identifying as white non-Hispanic, black non-Hispanic and Hispanic, with 3.4% identifying as Asian. …”
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Institutional priorities and student engagement: a multi-stakeholder analysis of physical education in Israel by Ali Alayan, Ahmad Salhab, Paz Carmel, Ronit Ahdut HaCohen

“…Instrument reliability was confirmed via Cronbach's alpha coefficients (≥0.70), and data were analyzed using descriptive statistics and chi-square tests.ResultsAlthough 83% of students rated PE as equally important as other academic subjects, 70.7% reported receiving only one hour per week. …”
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Psychiatrists’ experiences with the implementation of safewards and other quality improvement work: an explorative, qualitative interview study by Martin Lindow, Mårten J. Tyrberg, Veikko Pelto-Piri, Anna Björkdahl

“…This study aimed to identify key facilitators and barriers to psychiatrists’ engagement in implementing Safewards and other quality improvement work. Methods In this qualitative exploratory study, semi-structured interviews and inductive content analysis were utilized. …”
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Non-menstrual pelvic symptoms and women's quality of life: a cross-sectional observational study. by Marlon de Freitas Fonseca, Felipe Ventura Sessa, Claudio Peixoto Crispi, Nilton de Nadai Filho, Bruna Rafaela Santos de Oliveira, Rafael Ferreira Garcia, Claudio Peixoto Crispi

“…This study aimed to compare the relative burdens of 4 different non-menstrual pelvic symptoms on HQoLife: Deep dyspareunia (DDyspareunia), non-menstrual pelvic pain (NMPelvicPain), non-menstrual dyschezia (NMDyschezia) and non-menstrual dysuria (NMDysuria).<h4>Subjects and methods</h4>This is a pre-planned cross-sectional interdisciplinary retrospective observational study. …”
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Views on patient portal use for adolescents in mental health care - a qualitative study by Martine Stecher Hornum, Aslak Steinsbekk, Torunn Hatlen Nøst

“…Most informants thought that healthcare providers should have the autonomy to determine which information should be shared with whom, but also requested guidelines to ensure equal practice and support in difficult situations. …”
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A Prospective Tumour Marker for Breast Cancer: YWHAB and Its Role in Promoting Oncogenic Phenotypes by Gopaul VL, Winstone L, Gatien BG, Nault BD, Maiti S, Opperman RM, Majumder M

“…The potential of YWHAB as a therapeutic target or biomarker for BRCA is investigated here.Methods: After YWHAB was knocked down with siRNA, BRCA cell lines were used for in vitro assays (proliferation, migration, epithelial-to-mesenchymal transition). …”
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Enhanced phoxim biodegradation by immobilizing Novosphingobium sp. RL4 on attapulgite-sodium alginate by Tong Peng, Tong Peng, Yining Huang, Tao Yang, Tao Yang, Yinquan Wang, Ling Jin

“…Based on the specific surface area, mass-transfer performance results, adsorption isotherms, and degradation efficiency, the addition of ATP or BC to SA has an equally positive impact on the degradation of phoxim by immobilized microspheres. …”
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