Standalone cages versus plate-augmented fusion in multilevel anterior cervical discectomy and fusion: A 12-month prospective study balancing clinical equivalence and radiological s... by Sayed Mohamed Elgoyoushi

“…This prospective study compares the clinical and radiological outcomes of standalone cages versus plate-augmented systems in multilevel ACDF, addressing critical debates on biomechanical stability versus procedural simplicity. Materials and Methods: A prospective cohort of 100 patients undergoing multilevel ACDF (2+ levels) was equally divided into two groups: standalone cages (Group I, n = 50) and cages with ACP (Group II, n = 50). …”
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Transferrin and Borneol-Enhanced Liposomes for Targeted Rapamycin Delivery in TBI by Cai S, Yuan Z, Chen Y, Gong M, Lai J, Yan P, Mei Z

“…We developed transferrin-modified rapamycin and borneol co-delivery liposomes (TF-RAPA/BO-LIP) to overcome these barriers, aiming to enhance both drug delivery to the brain and the treatment efficacy.Methods: We employed the emulsion-solvent evaporation method to prepare TF-RAPA/BO-LIP and characterized their particle size, zeta potential, morphology, stability, and encapsulation efficiency. …”
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Effect of 12 weeks of selective cardiorespiratory endurance and plyometrics training on 800-meter rural collegiate athletes: a randomised controlled trial by Neeraj Kumar, Anand N. Badwe

“…Participants were randomly allocated into two equal groups (group A and group B). Group A received only conventional training, including cardiorespiratory endurance training (CON), while group B received plyometric training combined with conventional training, including cardiorespiratory endurance training (PLYO). …”
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What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. by Janne Marieke Veerbeek, Erwin van Wegen, Roland van Peppen, Philip Jan van der Wees, Erik Hendriks, Marc Rietberg, Gert Kwakkel

“…Neurological treatment approaches to training of body functions and activities showed equal or unfavorable effects when compared to other training interventions. …”
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Diagnostic value of Epstein – Barr virus DNA quantification in blood leukocytes in children with infectious mononucleosis by M. I. Popkova, E. N. Filatova, E. A. Soboleva, D. A. Bryzgalova, E. A. Kulova, N. A. Sakharnov, O. V. Utkin

“…To determine the threshold value of the Epstein-Barr virus (EBV) viral load (VL) in blood leukocytes to improve the laboratory diagnostics of infectious mononucleosis in children.Materials and methods. EBV DNA quantification in blood leukocytes in children aged 1-17 years (n=163) was determined by real-time polymerase chain reaction. …”
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Successful Treatment of Immune Checkpoint Inhibitor–Induced Bullous Pemphigoid with Omalizumab: A Case Report and Review of the Literature by Chen J, Xu D, He Z, Ma S, Liu J, Dai X, Luo Y, Ye X

“…However, ICIs can lead to immune-related adverse events (irAEs), including dermatologic manifestations such as bullous pemphigoid (BP).Objective: To evaluate the efficacy and safety of omalizumab and other biologics in the treatment of ICI-induced refractory bullous pemphigoid and to derive a strategy for selecting biologic treatments for this condition.Methods: A 48-year-old female with pulmonary squamous cell carcinoma developed erythema and blisters following tislelizumab treatment. …”
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Adjunctive antihypertensive therapy of primary glaucoma with a fixed combination drug of 1% brinzolamide and 0.5% timolol: efficacy and safety by S. Yu. Petrov, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan, L. V. Vasilenkova, O. M. Filippova, A. N. Zhuravleva, O. I. Markelova

“…Purpose: a comparative study of the efficacy and safety of the combination drug Brinzopt Plus and the original drug Azarga used as adjunctive therapy in patients with primary open-angle glaucoma (POAG) previously treated with latanoprost.Material and methods. 30 patients (42 eyes) with advanced and far advanced POAG were randomly divided into 2 groups of equal size. …”
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Minimally invasive pouch technique with leukocyte platelet rich fibrin compared to non-invasive hyaluronic acid injection in reconstruction of interdental papilla in esthetic zone:... by Aya Alleithy, Hala Abuel-Ela, Susan Sarhan

“…Patients with deficient interdental papilla class I or II in the esthetic zone were selected, then patients were randomized using computer-generated block randomization into two equal groups: group A (L-PRF) and group B (HA gel). …”
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Amphotericin B Colloidal Dispersion is Efficacious and Safe for the Management of Talaromycosis in HIV-Infected Patients: Results of a Retrospective Cohort Study in China by Liu M, Yang H, Liu Q, He K, Yuan J, Chen Y

“…This study aimed to compare the efficacy and safety of Amphotericin B Colloidal Dispersion (ABCD) and AmB-D for the treatment of talaromycosis in a retrospective cohort of HIV-infected patients.Methods: This was a retrospective study and the data of HIV-infected patients with talaromycosis who received ABCD or AmB-D from January 2018 to December 2022, were retrospectively collected and analyzed. …”
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Microtensile bond strength of CAD/CAM-fabricated polymer-ceramics to different adhesive resin cements by Leyla Sadighpour, Farideh Geramipanah, Zahra Ghasri, Mehrnoosh Neshatian

“…ObjectivesThis study evaluated the microtensile bond strength (µTBS) of polymer-ceramic and indirect composite resin with 3 classes of resin cements.Materials and MethodsTwo computer-aided design/computer-aided manufacturing (CAD/CAM)-fabricated polymer-ceramics (Enamic [ENA; Vita] and Lava Ultimate [LAV; 3M ESPE]) and a laboratory indirect composite resin (Gradia [GRA; GC Corp.]) were equally divided into 6 groups (n = 18) with 3 classes of resin cements: Variolink N (VAR; Vivadent), RelyX U200 (RXU; 3M ESPE), and Panavia F2 (PAN; Kuraray). …”
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Distribution and Antibiotic Resistance Analysis of 13,048 Clinically Common Isolates by Zhao J, Yue P, Li ZJ, Xu T, Xing GZ, Shao Y, Yu HY

“…Jing Zhao,1,* Peng Yue,2,* Zhi-jie Li,3,* Ting Xu,1 Guo-zheng Xing,1 Yan Shao,1 Hong-yuan Yu1 1Department of Clinical Laboratory, Beijing Aerospace General Hospital, Beijing, People’s Republic of China; 2Northern Medical Branch of PLA General Hospital, Haidian, Beijing, 100080, People’s Republic of China; 3Obstetrics and Gynecology, Beijing Aerospace General Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong-yuan Yu, Email 13051839088@163.comObjective: This study investigated the distribution and antibiotic resistance profiles of common bacteria isolated from clinical specimens at a hospital’s microbiology laboratory between 2020 and 2022.Methods: A retrospective analysis was conducted on microbial culture results from clinical specimens collected over three years, including sample types, departmental distribution, pathogen species, and resistance profiles.Results: A total of 13,048 unique pathogenic strains were isolated, predominantly from respiratory and urine specimens. …”
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Network Analysis of Depressive Symptoms, Social Support, and Diabetes Distress Among Patients with Type 2 Diabetes: A Cross-Sectional Study by Chen H, Dong X, Chen S, Chen X, Lu X, He J, Ji W, Hou C, Bai D, Gao J

“…This study aimed to identify the central components of DD and to examine the interconnectedness between DS, SS, and DD components.Methods: A cross-sectional survey design was employed in this study. …”
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Relative Factors Analysis of the Occurrence and Location of Intratracheal Granuloma Following Tracheotomy by Li W, Hu Y, Hu Y, Zhou M, Li Y, Peng J

“…This study investigates the relationship between clinical factors and the occurrence and location of intratracheal granuloma.Methods: Clinical parameters from 872 patients who underwent tracheotomy between January 1, 2010, and December 30, 2018, were collected from the Hospital Information System. …”
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Initial hypotensive therapy of primary glaucoma with the domestic latanoprost generic: efficacy and safety by S. Yu. Petrov, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan, L. V. Vasilenkova, O. M. Filippova, A. N. Zhuravleva

“…Purpose: a comparative study of the efficacy and safety of the Latanoprost-Optic drug and the original latanoprost drug administered to previously untreated patients with primary open-angle glaucoma (POAG). Material and methods. A double-blind, randomized, parallel-group study involved 60 patients (70 eyes) with newly diagnosed POAG, who were randomly divided into 2 groups of equal size. …”
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Altered regional homogeneity in patients with unilateral acute open globe injury: a resting-state functional MRI study by Huang X, Li H, Ye L, Zhang Y, Wei R, Zhong Y, Peng D, Shao Y

“…Each subject underwent a resting-state functional magnetic resonance imaging scan. The ReHo method was used to assess local features of spontaneous brain activity. …”
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Health status, functioning and risk profiles for secondary health conditions in adolescents and young adults with spina bifida: a cross-sectional study at time of transition by Inge Eriks-Hoogland, Moritz Schwethelm, Lorena Müller, Jivko Stoyanov, Jürgen Pannek, Marija Glisic

“…Descriptive statistics were used to describe the study population and to analyse the frequency and co-occurrence of congenital and acquired secondary health conditions. The equality of proportions test was used to test the prevalence of secondary health conditions based on important personal and clinical characteristics. …”
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Cumulative effect and subchronic toxicity of the supramolecular complex of fenbendazole by A. I. Varlamova

“…The purpose of the research is to study the cumulative effect and subchronic toxicity of supramolecular complex of fenbendazole (SMCF).Materials and methods. The cumulative effect of SMCF was studied on 20 outbred white rats weighing 180 g that were divided into experimental and control groups of 10 animals each. …”
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INFLAMMATORY-DESTRUCTIVE PROCESS IN PERIODONTIUM WHILE MODELLING HYPО- AND HYPERREACTIVITY OF THE ORGANISM by Yu.Yu. Yarov

“…The animals were divided into three equal groups. In the first group, drugs that disrupt the reactivity of the organism were not used (normoreactivity of the organism). …”
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Association of a Liver Allocation Policy Change With Domestic Travel for Liver Transplantation by Katie Ross-Driscoll, PhD, MPH, Chandrashekhar Kubal, MD, PhD, Arrey-Takor Ayuk-Arrey, MPH, Jonathan Fridell, MD, David Axelrod, MD, MBA

“…Changes to allocation policy alone may not equalize patient means or desire to travel for transplant care.…”
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Mannitol versus mannitol with hypertonic saline for brain relaxation during craniotomies using ultra-sonographic optic nerve sheath diameter by Eslam Mohammed Ahmed El-Genaidy, Said Mohamed El-Medany, Ashraf Arafat Abdelhalim, Ragab Saad Beltagy, Tarek Ahmed Rayan

“…Background This study compared the effect of conventional doses of mannitol alone versus combined lower doses of mannitol-hypertonic saline on brain debulking during elective craniotomies.Patients and methods Sixty participants aged 18–60 years, ASA class I or II, who were scheduled for elective supratentorial brain tumor surgery, were randomly separated into 2 equal groups. …”
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