The influence of nitric oxide delivery on the processes of apoptosis, necroptosis and pyroptosis in the renal parenchyma after simulating cardiopulmonary bypass: an experimental st... by M. A. Tyo, N. O. Kamenshchikov, Yu. K. Podoksenov, A. V. Mukhomedzyanov, L. N. Maslov, I. V. Kravchenko, E. A. Churilina, B. N. Kozlov

“…The objective was to study the effect of the delivery of exogenous nitric oxide on the severity of apoptosis, pyroptosis, and necroptosis of the renal parenchyma after simulating cardiopulmonary bypass and cardiopulmonary bypass with circulatory arrest.Materials and Methods. 24 Altai breed rams were randomized into 4 equal groups. …”
Get full text

Modeling human capital strategies with an emphasis on organizational structure change by Shahriyar Emamdoust Haredasht, Musa Rezvani Chaman Zamin, Morteza Hazrati

“…Finally, it is suggested that in order to create more motivation and effort from employees and consequently increase their productivity, the distribution of rewards among employees with higher productivity should be continuous and equal. Research Methodology This research is an applicable research in terms of its purpose, and quantitative in terms of its method. …”
Get full text

Ex vivo-model design and evaluation of the sensitivity of blast cells to chemotherapy as a way to personalize the treatment of acute myeloid leukemia by A. S. Polyakov, Ya. A. Noskov, Yu. V. Nikitin, V. V. Tyrenko, S. N. Kolubaeva, A. N. Bogdanov, V. N. Semelev, O. R. Petrova, S. V. Bondarchuk, D. K. Zhogolev, A. D. Zolotarev, A. V. Kovalev, Yu. E. Puchkova

“…Drugs made with a more complete understanding of the biology of acute myeloid leukemia do not equal the hopes for better prognosis. The best results are achieved only with high-dose chemotherapy, which is only possible for a limited number of patients. …”
Get full text

The inclusion of insect meal from Hermetia illucens larvae in the diet of laying hens (Hy-line Brown) affects the caecal diversity of methanogenic archaea by Tiziana Maria Mahayri, Jakub Mrázek, Fulvia Bovera, Giovanni Piccolo, Giovanni Andrea Murgia, Giuseppe Moniello, Kateřina Olša Fliegerová

“…The effect of the dietary inclusion of Hermetia illucens larvae meal on the diversity of the methanogenic archaea in the caecum of laying hens (Hy-line Brown) was investigated using molecular methods. A total of 27 hens, selected equally for slaughter from 162 birds which were divided equally into 3 treatment groups including control group C with a diet containing corn-soybean meal and 2 experimental groups, HI25 and HI50, in which 25% and 50% of the soybean meal protein was replaced by the protein from a Hermetia illucens larvae meal, respectively. …”
Get full text

The Influence of Loneliness on Pain Outcomes for Adolescents: A Cross-Sectional Survey by Paula A. Forgeron, Jennifer Stinson, Kathryn Birnie, G Allen Finley, Abbie Jordan, Pamela Qualter, Ligyana Candido, Michelle Lamont, Cassidy Bradley, Delane Linkiewich, Trinity Lowthian, Samuel McNally, Natasha Trehan, Bruce Dick

“…This study describes the types of peer loneliness (intimate, relational, and collective) experienced by these adolescents and the impact that peer loneliness has on pain-related outcomes.Methods A cross-sectional online survey was completed by 128 Canadian adolescents aged 12–18 years who experienced pain for at least 3 months. …”
Get full text

Overweight effects on metabolic rate, time perception, diseases, aging, and lifespan: A systematic review with meta-regression analysis by Kuat Oshakbayev, Aigul Durmanova, Altay Nabiyev, Antonio Sarria-Santamera, Alisher Idrissov, Gulnara Bedelbayeva, Abduzhappar Gaipov, Ayan Mitra, Meruyert Gazaliyeva, Bibazhar Dukenbayeva, Gani Kuttymuratov

“…Trial registration: ClinicalTrials.gov NCT06410352 (05/08/2024): https://register.clinicaltrials.gov/prs/app/action/SelectProtocol?sid=S000EG8K&selectaction=Edit&uid=U0006MBT&ts=56&cx=-vph5l9.…”
Get full text

New cationic chlorin as potential agent for antimicrobial photodynamic therapy by N. V. Suvorov, V. V. Shchelkova, E. V. Rysanova, Z. T. Bagatelia, D. A. Diachenko, A. P. Afaniutin, Yu. L. Vasil’ev, E. Yu. Diachkova, I. C. Santana Santos, M. A. Grin

“…One of these innovative methods is antimicrobial photodynamic therapy (APDT), which is equally effective against antibiotic-sensitive and antibiotic-resistant pathogens. …”
Get full text

Atrophy trajectories in Alzheimer’s disease: how sex matters by Anna Inguanzo, Konstantinos Poulakis, Javier Oltra, Silvia Maioli, Anna Marseglia, Daniel Ferreira, Rosaleena Mohanty, Eric Westman, Alzheimer’s Disease Neuroimaging Initiative

“…The impact of sex on the progression of these subtypes remains a crucial area of investigation. Methods We analysed MRI data from 320 amyloid-β positive individuals with AD from three international cohorts (ADNI, J-ADNI and AIBL). …”
Get full text

Evolution of means and principles of smallpox vaccination by S. V. Borisevich, V. N. Podkuyko, A. P. Pirozhkov, A. I. Terent'ev, V. P. Krasnyansky, E. V. Rozhdestvensky, S. V. Nazarov, S. V. Kuznecov

“…The third generation were the vaccines based on vaccine strains at-tenuated by various methods. Fourth, DNA vaccines and subunit recombinant vaccines. …”
Get full text

Soil-water retention capacity of expansive soil improved through enzyme induced carbonate precipitation-eggshell powder by Yunlong Liu, Yanyan Xia, Mudassir Mehmood, Lei Wang, Wen Nie, Yingao Zhao, Zhencai Luo

“…Moreover, the reuse of ESP provides a sustainable solution for the resource utilization of agricultural waste and the improvement of expansive soil using bio-inspired methods.…”
Get full text

A Novel Concept of the “Standard Human” in the Assessment of Individual Total Heart Size: Lessons from Non-Contrast-Enhanced Cardiac CT Examinations by Maciej Sosnowski, Zofia Parma, Marcin Syzdół, Grzegorz Brożek, Jan Harpula, Michał Tendera, Wojciech Wojakowski

“…We proposed a novel body size indexing measure that may outperform common indices for quantifying total heart volume (THV). <b>Methods:</b> This index is the sum of height and the difference between height (unitless) and body surface area (unitless), [h+(h-BSA)], and if the (h-BSA) equals “zero”, it is a feature of the “standard human”. …”
Get full text

Applying Multi-Sensor Satellite Data to Identify Key Natural Factors in Annual Livestock Change and Winter Livestock Disaster (<i>Dzud</i>) in Mongolian Nomadic Pasturelands by Sinkyu Kang, Nanghyun Cho, Amartuvshin Narantsetseg, Bolor-Erdene Lkhamsuren, Otgon Khongorzul, Tumendemberel Tegshdelger, Bumsuk Seo, Keunchang Jang

“…Summer and winter variables appeared to be almost equally important in both models. The primary factors of livestock change and <i>Dzud</i> showed regional patterns: dryness in the south, temperature in the north, and foraging resource in the central and western regions. …”
Get full text

Effect of polarization potential on tribocorrosion behavior of duplex stainless steel UNS S32205 in NaCl solution by Jomar José Knaip Ribeiro, Oriana Palma Calabokis, Yamid Enrique Nuñez de la Rosa, Silvio Francisco Brunatto, Paulo César Borges

“…Finally, this study allowed the determination of the great effect of the potential applied on the tribocorrosion behaviour and the identification of differences between the cathodic protection and distilled water assays as methods to inhibit corrosion.…”
Get full text

Prenatal Rosiglitazone Administration to Neonatal Rat Pups Does Not Alter the Adult Metabolic Phenotype by Hernan Sierra, Reiko Sakurai, W. N. Paul Lee, Nghia C. Truong, John S. Torday, Virender K. Rehan

“…This study aimed to determine the effects of prenatally administered RGZ on the metabolic phenotype of adult rats. Methods. Pregnant Sprague-Dawley rat dams were administered either placebo or RGZ at embryonic days 18 and 19. …”
Get full text

Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway by Jingsong Wang, Qingyuan Zheng, Jun Jian, Xiuheng Liu, Zhiyuan Chen, Shanshan Wan, Lei Wang

“…Objective(s): To explore the effects of puerarin on renal ischemia/reperfusion injury and the possible mechanism.Materials and Methods: The experimental mice were injected with puerarin (50 or 100 mg/kg) per day or equal sterile saline by intraperitoneal injection for one week, and a renal I/R injury model was constructed. …”
Get full text

Pedigree investigation and predictive gene testing of the APC gene for colonic adenomatous polyposis by Fang Ruihua, Wang Zhaoming, Qiu Xiaoqian, Zhu Weiye, Ge Sai, Wang Chenglong, Qiu Geng, Gao Xianhua, Xu Xiaodong, Xing Junjie, Wang Hao, Zhang Wei, Yu Enda, Zhao Ziye

“…Specifically, when the age of the subjects is less than or equal to 25 years old, the detection rate approaches 50%.…”
Get full text

Conflict of Interest Disclosure in American Arthroplasty Surgical Literature by Robert T. Tisherman, MD, Richard A. Wawrose, MD, Aditya M. Mittal, BS, Stephen R. Chen, MD, Joseph Chen, BS, Christopher J. Como, MD, Malcolm Dombrowski, MD, Jeremy D. Shaw, MD

“…The total value of disclosed COI equaled $1.71 billion. The total value of undisclosed conflicts of interest equaled $334 million. …”
Get full text

Technical considerations regarding saliva sample collection to achieve comparable protein identification and detection via one- and two-dimensional gel electrophoresis among humans by Szabolcs Maar, Lilla Czuni, Jørgen Kosberg Hassve, Aniko Takatsy, Szilard Rendeki, Tibor Mintal, Ferenc Gallyas, Jr., Ildiko Bock-Marquette

“…Moreover, for superb interpretation, it became equally significant to obtain the information from the same exact specimen. …”
Get full text

Is extra virgin olive oil a promising remedy for reducing the impact of postmenopausal osteoporosis? An experimental study by El-Sayed El-Shafaey, El-Sayed El-Shafaey, Eman Ali, Magda Elkomy, Mohamed Abdo Rizk, Saleh Altuwaijri, Saleh Albarrak

“…Therefore, this study aims to provide a potentially novel therapeutic approach by examining olive oil's effects on bone mineral density (BMD), biochemical markers, biomechanical properties, and histopathological changes in an ovariectomized (OVX) rat model.MethodsIn this study, Twenty-four 6-month-old female Wistar rats were randomly allocated into four equal groups (n = 6 rats, for each group): control group, rats given 1mL/100g olive oil, ovariectomized rats (OVX-group), and OVX rats treated with olive oil. …”
Get full text

Serum vitamin D levels in older adults with and without dyslipidemia: A comparison using baseline data from the Birjand Longitudinal Aging Study (BLAS) by Fatemeh Alizadeh, Fatemeh Salmani, Farshad Sharifi, Mitra Moodi, Masomeh Khorashadizadeh, Zoya Tahergorabi

“…Summary: Background &amp; Aims: Nowadays, research on extraskeletal effects of Vitamin D on human health is growing This study aimed to Serum vitamin D levels measurement in older adults with and without dyslipidemia: a comparison using baseline data from the Birjand Longitudinal Aging Study (BLAS). Methods: This cross-sectional study included 420 elderly people over 60 years old divided into in two equal groups with and without dyslipidemia. …”
Get full text