Predicting OSA Using Radiographs of the Airway Anatomy by Du M, Gui Y, Guo Y, Liu J, Deng W, Huang J, Liu T, Zhang X, Pang F

“…., Guangzhou, 510000, People’s Republic of China; 4Department of Anesthesiology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 5Department of Otolaryngology Head and Neck Surgery, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiangmin Zhang; Feng Pang, Department of Sleep Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26 Yuanchun Two Road, Guangzhou, Guangdong, 510065, People’s Republic of China, Tel +86 15013071537, Email zhangxm36@mail.sysu.edu.cn; pangf6@mail.sysu.edu.cnObjective: This study aims to analyze the tongue body shape and upper airway anatomical parameters in patients with Obstructive Sleep Apnea (OSA) and to explore the anatomical causes of OSA.Methods: A total of 345 subjects participated in this study. …”
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Comparative Analysis of Clinical Efficacy and Safety of Pyrotinib Plus Capecitabine versus Trastuzumab Emtansine (T-DM1) as Second-Line Treatment for HER2-Positive Advanced Breast... by Han H, Wang C, Jiang F, Sun P, Liu J

“…This study aims to compare the clinical efficacy and safety of T-DM1 against pyrotinib plus capecitabine.Methods: Patients are females with HER2-positive, locally advanced, or metastatic breast cancer who at least 18 years old and have received anti-HER2 therapy in the past. …”
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Preoperative Neutrophil-to-Albumin Ratio as a Prognostic Indicator in Advanced Gastric Cancer Undergoing Radical Gastrectomy by Ye H, Kang R, Chen M, Zhang S, Yang J

“…Huaping Ye,1,* Rong Kang,2,* Mao Chen,3 Si Zhang,3 Jinfeng Yang1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 3Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinfeng Yang, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email yangjinfeng13@163.com Si Zhang, Department of Emergency Medicine, The First Affiliated Hospital of Chengdu Medical College, No. 278, The Middle Section of Baoguang Avenue, Xindu District, Chengdu City, Sichuan Province, 610500, People’s Republic of China, Email 692653629@qq.comObjective: This study aimed to evaluate the prognostic significance of the preoperative neutrophil-to-albumin ratio (NAR) in patients with advanced gastric cancer undergoing radical gastrectomy.Methods: A retrospective analysis was conducted involving 526 patients diagnosed with locally advanced gastric adenocarcinoma who underwent radical gastrectomy between January 2017 and December 2019. …”
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Association Between Dietary Flavonoid Intake and Cardiovascular Health in Cancer Survivors: A Cross-Sectional Study by Li J, Chen G, Xie Z, Lin J, Luo S, Xu S

“…The purpose of this study was to explore the associations between dietary flavonoid intake and cardiovascular health in cancer survivors.Patients and Methods: We obtained data from the National Health and Nutrition Examination Survey (NHANES) 2007– 2008, 2009– 2010, and 2017– 2018 cycles. …”
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Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses by Chen S, Sun S, Zhou Z, Zhou Z, Zhang R, Song W, Xin H, Yang Q, Dai S, Huang K, Niu W, Shi H, Guo Y

“…However, little is known about the causal relationship between immune factors and diseases of the reproductive system.Methods: Thorough two-sample Mendelian randomization (MR) analyses were conducted to determine the causal effects of 731 immune traits on reproductive ill-health, including abnormal spermatozoa (AS), polycystic ovary syndrome (PCOS), and spontaneous abortion (SA). …”
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Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson’s Disease by Wen X, Cao W, Ding H, Chen A, Sun Z, Wang Y, Xi Y, Wu S

“…The present study was to test this hypothesis.Methods: EVs isolated from FGF2-primed astrocytes (FGF2-EVs) were characterized by transmission electron microscopy and nanoparticle tracking analysis. …”
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A Comparison of Stereotactic Radiation Therapy in Elderly Patients with Central or Peripheral Stage I-II (T1-3 N0 M0) Non-Small Cell Lung Cancer by Ji X, Shi X, Hu J, Jiang W, Zhou B, Zhou H, Yuan X, Li Y, Huang H, Wang J, Ding W, Wang Y, Sun X

“…Xiaoqin Ji,1,* Xuebing Shi,2,* Jun Hu,3 Wanrong Jiang,3 Bin Zhou,3 Houlong Zhou,3 Xi Yuan,3 Yikun Li,3 Hua Huang,3 Jiasheng Wang,3 Wei Ding,3 Yong Wang,4 Xiangdong Sun3 1Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 2Department of Radiation Oncology, Nanjing Jiangbei Hospital, Nanjing, People’s Republic of China; 3Department of Radiation Oncology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 4Department of Outpatient Clinic, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yong Wang; Xiangdong Sun, Email 292917354@qq.com; sunxd_81@126.comPurpose: The objective of this study was to compare the clinical outcomes of stereotactic body radiation therapy (SBRT) in elderly patients aged 65 or older with clinical stage I–II non-small-cell lung cancer (NSCLC), specifically examining the differences between centrally located lung tumors and peripherally located lung tumors.Methods: From April 2009 to January 2020, a total of 136 patients with 136 tumors (65 central, 71 peripheral; NSCLC) at an early stage (T1-3N0M0) were treated with SBRT at a single institution. …”
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Clinical Features of Juvenile Open-angle Glaucoma by A. V. Malyshev, A. S. Apostolova, A. A. Sergienko, A. F. Teshev, G. Yu. Karapetov, M. K. Ashhamahova, B. N. Hatsukova

“…Juvenile open-angle glaucoma (JOAG) is a genetically determined disease of young age, which is diagnosed before the 40, which is based on anomalies in the structure of the drainage system of the eye.Objective: to identify the features of morphometric and biomechanical parameters of the fibrous capsule in patients with JOAG.Materials and methods. 19 eyes of 10 patients with JOAG were examined. …”
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Impact of Fungal Co-Infection on Teicoplanin Plasma Trough Concentration in Critically Ill Adults: A Novel Consideration for Dose Adjustment by Cheng L, Wang L, You X, Xiong L, Dai Q, Wang Q

“…However, the effect of fungal co-infection on the plasma trough concentration (Cmin) of teicoplanin in critically ill patients remains unclear.Materials and Methods: A retrospective cohort study was carried out. …”
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Relative contribution of diet and physical activity to increased adiposity among rural to urban migrants in India: A cross-sectional study. by Sanjay Kinra, Poppy Alice Carson Mallinson, Jenny A Cresswell, Liza J Bowen, Tanica Lyngdoh, Dorairaj Prabhakaran, Kolli Srinath Reddy, Mario Vaz, Anura V Kurpad, George Davey Smith, Yoav Ben-Shlomo, Shah Ebrahim

“…<h4>Conclusions</h4>We found that increased energy intake and reduced energy expenditure contributed equally to greater adiposity among urban migrants in India. …”
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The Aggregate Index of Systemic Inflammation (AISI) is a Novel IgA Nephropathy Prognosis Predictor by Liu H, Tang G, Yu D, Gu P, Zhu X, Wang A, Yuan Y, Jiang X

“…We aimed to evaluate its predictive value in IgAN.Patients and Methods: This retrospective single-center study included 1792 biopsy-confirmed IgAN patients from October 2019 to September 2023 with> 12-month follow-up. …”
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Changes in Serum Bilirubin and Total Bile Acids During Biologic Therapy in Patients with Ulcerative Colitis: A Retrospective Study by Ren Z, Zhang Z, Li H, Fu P, Wang R, Wang S, Li Y

“…This study aims to assess their monitoring potential in UC during biologic therapy.Methods: We conducted a retrospective single-center study including 138 UC patients and 150 controls with normal colonoscopy results. …”
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Cancer-Derived Exosomal LINC01615 Induces M2 Polarization of Tumor-Associated Macrophages via RBMX-EZH2 Axis to Promote Colorectal Cancer Progression by Li A, Hong J, Ma X, Huang Y, Jiang Q, Zhang C, Wang Y, Huang Y

“…However, the specific role of cancer derived exosomal lncRNA in the M2 polarization of macrophages remains largely unknown.Methods: Bioinformatic analysis was used to screen out the differentially expressed lncRNAs in colorectal cancer (CRC). …”
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Auxiliary Diagnosis of Pulmonary Nodules&amp;rsquo; Benignancy and Malignancy Based on Machine Learning: A Retrospective Study by Wang W, Yang B, Wu H, Che H, Tong Y, Zhang B, Liu H, Chen Y

“…Its nonspecific clinical presentation and heterogeneous imaging characteristics hinder accurate differentiation between benign and malignant lesions, while biopsy’s invasiveness and procedural constraints underscore the critical need for non-invasive early diagnostic approaches.Methods: In this retrospective study, we analyzed outpatient and inpatient records from the First Medical Center of Chinese PLA General Hospital between 2011 and 2021, focusing on pulmonary nodules measuring 5– 30mm on CT scans without overt signs of malignancy. …”
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Prediction of Abnormal Functional Performance in Chronic Obstructive Pulmonary Disease Using Respiratory Models: A Pilot Study by Ribeiro CO, Lopes AJ, de Melo PL

“…Caroline Oliveira Ribeiro,1,&amp;ast; Agnaldo José Lopes,2,&amp;ast; Pedro Lopes de Melo1,3,&amp;ast; 1Biomedical Instrumentation Laboratory - Institute of Biology and Faculty of Engineering, State University of Rio de Janeiro, Rio de Janeiro, Brazil; 2Pulmonary Function Laboratory, State University of Rio de Janeiro, Rio de Janeiro, Brazil; 3BioVasc Research Laboratory - Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil&amp;ast;These authors contributed equally to this workCorrespondence: Pedro Lopes de Melo, Email plopes@uerj.brIntroduction: The contribution of respiratory models to understanding and predicting functional capacity abnormalities in chronic obstructive pulmonary disease (COPD) has not yet been investigated.Purpose: The aims of this study were: (1) To investigate the associations between the extended Resistance-Inertance-Compliance (eRIC) and the fractional-order (FrOr) models with changes in Glittre-ADL and handgrip tests and; (2) To evaluate the accuracy of these models in predicting abnormal functional capacity in COPD.Patients and Methods: The study was carried out in a group of 40 adults with COPD and a control group of 40 healthy individuals, both evaluated by respiratory oscillometry, spirometry, Glittre-ADL test and handgrip test. eRIC and fractional order models were also used to quantify biomechanical changes and obtain physiological information. …”
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Prevalence of Urinary Incontinence, Risk Factors and Its Impact: Multivariate Analysis from Indonesian Nationwide Survey by Rochani Sumardi, Chaidir A Mochtar, Junizaf Junizaf, Budi I Santoso, Siti Setiati, Siti A Nuhonni, Partini P Trihono, Harrina E Rahardjo, Firtantyo A Syahputra

“… Aim: to describe the profile of urinary infection (UI) and to analyze its risk factors and impacts. Methods: subjects were enrolled consecutively from pediatric, urology, obstetrics & gynecology, and geriatric outpatient clinics at six teaching hospitals in various regions of Indonesia. …”
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Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation by Li S, Zhu H, Zhai Q, Hou Y, Yang Y, Lan H, Jiang M, Xuan J

“…However, the therapeutic effects and potential mechanisms of Lang Qing Ata (LQAtta) against NASH remain elusive.Materials and Methods: The components of LQAtta were identified using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-MS/MS). …”
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Impact of Radiation Therapy Techniques on Hippocampal Doses and Psychological Status in Patients With Nasopharyngeal Carcinoma by Gai X, Huang S, Zeng J, Chen J, Liu F, Li S, Lv W, Guo F, Cai C, Hong J, Su L

“…Xiujuan Gai,1– 3,&ast; Shiqi Huang,1,2,&ast; Jiang Zeng,1,2,4 Jun Chen,1,2,4 Feng Liu,1,2,4 Shan Li,1,2,4 Wenlong Lv,1,2,4 Feibao Guo,1,2,4 Chuanshu Cai,1,2,4 Jinsheng Hong,1,2,4 Li Su1,2,4 1Department of Radiotherapy, Cancer Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, People’s Republic of China; 2Department of Radiotherapy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical Universisty, Fuzhou, Fujian, 350212, People’s Republic of China; 3Department of Oncology, Laiyang Central Hospital of Yantai, Yantai, 265200, People’s Republic of China; 4Key Laboratory of Radiation Biology of Fujian Higher Education Institutions, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Li Su; Jinsheng Hong, Department of Radiotherapy, Cancer Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, People’s Republic of China, Email lily2230@126.com; 13799375732@163.comPurpose: To investigate the impact of Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) on hippocampal radiation dosage and psychological status in patients newly diagnosed with nasopharyngeal carcinoma (NPC).Patients and Methods: A retrospective analysis was conducted on 269 NPC patients who received initial treatment between January 2013 and April 2022. …”
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Phytosomes Loaded with Mastoparan-M Represent a Novel Strategy for Breast Cancer Treatment by Zhao H, Bao S, Chen S, Yang Q, Lou K, Gai Y, Lin J, Liu C, Liu H, Zhang C, Yang R

“…Furthermore, we investigated the underlying anti-tumor mechanisms of Mast-M.Methods: The synthesis of Phy-Mast-M involved a co-solvent technique, followed by solvent evaporation. …”
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Age, Sex, and Symptom-Dependent Variations in Total IgE and Eosinophils in Atopic Patients: A Five-Year Retrospective Study by Zhao L, Wu Y, Zhu H, Lin Y, Su H, Hu J, Zhang M, Bao W

“…Age, sex and allergic symptoms may influence these biomarkers and the relationship among t-IgE, eosinophils, and atopic diseases remained unknown.Methods: A five-year retrospective study enrolled 7654 patients with allergic symptoms underwent allergen testing. …”
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