Effect of Position-Based Dosing Strategy for Metaraminol on Neonatal Acid–Base Status During Elective Caesarean Delivery: A Noninferiority Randomised Controlled Trial by Liu T, Jiang H, Xu C, Li L, Zhang H, Feng Y

“…We hypothesize that using a higher starting dose of metaraminol in the supine position will result in a non-inferior umbilical arterial pH, compared to the 15° left tilt position.Methods: Healthy women undergoing elective caesarean delivery were randomized to the supine position (n = 62) or 15° left tilt position (n = 62) after spinal anaesthesia (0.5% bupivacaine 9 mg). …”
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Successful Treatment of Freckles Using a 730-nm Picosecond Laser: A Prospective Study by Huang Y, Liu X, Zhang M, Lin T

“…This study aims to evaluate the efficacy and safety of a novel 730‐nm Ti: Sapphire picosecond laser in the treatment of freckles in Chinese patients.Methods: A total of 12 patients with freckles were enrolled. …”
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Campus closures and students’ mental health in Lebanon and Sharjah: A comparative cross-sectional study by Michael Clinton, Jacqueline Maria Dias, Myrna A. Doumit, Mohamad Alameddine, Murielle Mardi, Karen Bou- Karroum

“…Parametric test results were interpreted for non-equal sample sizes. Results: All the non-nursing students in Lebanon and 87.1 % of the nursing students in Sharjah screened positive for anxiety. …”
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Clinical and microbial study of reinforced 3D-printed maxillary denture base resin: a randomized trial by Eman Mohamed Ahmed Teama, Hoda Mohamed Amin Rashad, Eman Abd El-salam Mohamed Shakal, Eman Elsayed Hegazy

“…Purpose To evaluate the effects of adding nano ZrO2 and nano TiO2 on microbial colonization and patient satisfaction with 3D-printed maxillary complete dentures. Materials and methods Twenty-four patients who needed complete dentures were randomly distributed into three equal groups. …”
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A Strategy to Design Non-Symmetric Compound by Modifying the End-Group Functional Atoms for Photothermal and Photodynamic Therapy of Tumor by Xie X, Zeng J, Xu MY, Han XH, Fan B, Li X, Wei DD, Han XJ, Huang S

“…Xin Xie,1,2,* Jie Zeng,1,2,* Miao-Yan Xu,1,2 Xin-Hao Han,1 Bing Fan,3 Xianglong Li,4 Duo-Duo Wei,1,2 Xiao-Jian Han,1,5 Shaorong Huang1 1Institute of Geriatrics, Jiangxi Provincial People’s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, People’s Republic of China; 2School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 3Department of Radiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, People’s Republic of China; 4Jiangxi Key Laboratory of Organic Chemistry, Institute of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang, 330013, People’s Republic of China; 5The Second Department of Neurology, Jiangxi Provincial People’s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Jian Han; Shaorong Huang, Email hanxiaojian@hotmail.com; huangshaorong@ncmc.edu.cnBackground: The exploration of non-symmetric compound for combined photothermal therapy (PTT) and photodynamic therapy (PDT) in tumor treatment remains largely unexplored.Methods: Through a molecular design strategy, a series of compound (Y-4Cl, Y-2Br, and Y-2Cl-Br) with fused - ring benzothiazole - pyrrole - thiophene - indenone constructure were synthesized to explore its phototherapy properties, to investigate their phototherapeutic properties, respectively. …”
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Temporal and Seasonal Trends in Pediatric Eye Trauma in California by Bishay MN, Xu A, Nesemann JM, Keenan JD, Oatts JT

“…Proctor Foundation, University of California, San Francisco, CA, USA; 4Division of Ophthalmology, Children’s Hospital of Philadelphia, Scheie Eye Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA*These authors contributed equally to this workCorrespondence: Julius T Oatts, Division of Ophthalmology; Children’s Hospital of Philadelphia, Scheie Eye Institute, Perelman School of Medicine at the University of Pennsylvania, 3500 Civic Center Blvd, Philadelphia, PA, 19104, USA, Tel +1-215-590-2791, Email oattsj2@chop.eduPurpose: This study aims to evaluate temporal and seasonal trends in pediatric eye trauma based on emergency department (ED) visits in California.Design: Retrospective, population-based cohort study.Methods: Children who presented with ocular trauma to EDs in California between 2016 and 2021 were identified using the California Department of Health Care Access and Information datasets and classified by International Classification of Diseases (ICD) diagnosis codes. …”
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Comparative evaluation of aqueous solution and oil emulsion formulations of 0.05% cyclosporine eye drops in dry eye disease – A randomized clinical trial by Ayesha A Salam, Seema Sen, Neiwete Lomi, Noopur Gupta, Murugesan Vanathi, Radhika Tandon

“…Conclusion: Both aqueous solution and oil emulsion 0.05% cyclosporine formulations appear to be equally effective in the management of dry eye disease with a comparatively better response with oil emulsion formulations.…”
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Antidepressant use in the Canary Islands (Spain): a retrospective study of provincial, island and municipal trends and associated factors by Alexis Oliva, Vanessa Moreno, Mariana Sapino, Sandra Dévora, Susana Abdala-Kuri

“…To this end, several factors were analyzed, such as living in a rural or urban area, the population over 65 years of age, the population density or the socioeconomic status.MethodsData were extracted from the community pharmacy wholesaler at the population level. …”
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Efficacy and Safety of Aflibercept Biosimilars Relative to Reference Aflibercept Therapy for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis by Aljuhani HS, Hubayni RA, Qedair J, Bukhari ZM, Alzahrani A, Bawazir RO, Badghaish OS, Alqahtani F

“…Hazem Saleh Aljuhani,1,* Rahaf A Hubayni,2,3,* Jumanah Qedair,2,3 Ziad M Bukhari,4 Ahmed Alzahrani,4 Razan Osama Bawazir,2,3 Orjwan Salah Badghaish,2,3 Faisal Alqahtani5 1Ophthalmology Department, Jeddah Eye Hospital, Jeddah, Saudi Arabia; 2College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia; 3King Abdullah International Medical Research Center, Jeddah, Saudi Arabia; 4Ophthalmology Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia; 5Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia*These authors contributed equally to this workCorrespondence: Hazem Saleh Aljuhani, Ophthalmology Department, Jeddah Eye Hospital, Jeddah, Saudi Arabia, Tel +966545254296, Email Aljuhanihazem@gmail.comPurpose: To assess the efficacy and safety of aflibercept biosimilars compared to reference aflibercept therapy for neovascular age-related macular degeneration (nAMD) through a systematic review and meta-analysis.Methods: A comprehensive literature search was conducted across multiple databases. …”
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Evaluation of Applying Standardized Patients in Certification Assessment of Clinical Practice Ability Standardized Training for Psychiatric Resident Physicians by Yao F, Chen JS, Chen LH, Ye BY, Yang CJ, Li XZ

“…Fei Yao,1,2,* Jian-Song Chen,1,2,* Li-Hong Chen,1,2 Bi-Yu Ye,1,2 Chan-Juan Yang,1,2 Xuan-Zi Li1,2 1Department of Education, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, 510370, People’s Republic of China; 2School of Mental Health, Guangzhou Medical University, Guangzhou, Guangdong, 510370, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuan-Zi Li; Chan-Juan Yang, Department of Education, The Affiliated Brain Hospital, School of Mental Health, Guangzhou Medical University, No. 36 mingxin Road, Guangzhou, Guangdong, 510370, People’s Republic of China, Tel +86 20 81268042, Email lixuanzi@gzhmu.edu.cn; yangw2020@gzhmu.edu.cnObjective: The aim of this study was to explore the application of standardized patient (SP) in the certification assessment of clinical practice ability standardized training for psychiatric resident physicians.Methods: Candidates and examiners who participated in the graduation examination of clinical practice ability standardized training for psychiatric resident physicians in Guangdong Province from 2020 to 2023 were selected as the research participants. …”
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Circulating Interleukin-22 Is a Biomarker for Newly Diagnosed Type 2 Diabetes Mellitus and Associated with Hypoglycemic Effect of Sitagliptin by Sun P, Xiao Y, Dong Y, Feng Y, Zheng H, Liao X

“…This study aimed to assess serum IL-22 levels in participants with type 2 diabetes mellitus (T2DM) and analyze the association between IL-22 levels and T2DM risk.Methods: Serum IL-22 concentrations of recruited healthy participants (n=48), newly diagnosed T2DM participants (n=46), and T2DM participants receiving placebo (n=7) or dipeptidyl peptidase-4 inhibitors (DPP-4i) sitagliptin monotherapy (n=7) were measured using a commercial enzyme-linked immunosorbent assay (ELISA) kit. …”
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Comprehensive assessment of the quality of life in heart transplant recipients: experience at Shumakov National Medical Research Center of Transplantology and Artificial Organs by I. I. Muminov, A. A. Yusova, N. N. Koloskova, A. O. Shevchenko, R. Yu. Bangarov, M. S. Nesterova

“…For comparative analysis, HT recipients were divided into three equal groups based on the total score obtained when assessing each factor in the TxEQ questionnaire. …”
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Neutrophil Extracellular Traps Enhance Procoagulant Activity and Predict Poor Prognosis in Patients With Metastatic Breast Cancer by Gong Y, Chen B, Tan Q, Wei W

“…This study aims to determine whether NETs promote hypercoagulability and if NETs and plasma hypercoagulability markers are biomarkers of survival in MBC.Methods: Circulating levels of neutrophil extracellular trap (NET) markers and hypercoagulability markers (TAT, fibrinogen, and D-dimer) were assessed in 112 MBC patients before treatment, compared to 55 healthy controls. …”
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Comparison and Analysis on the Existing Single-Herbal Strategies against Viral Myocarditis by Yu Cao, Yang Liu, Tian Zhang, Jing Pan, Wei Lei, Boli Zhang

“…SLC6A2, SLC6A4, NOS2, PPARA, PPARG, ACHE, CYP2C19, CYP51A1, and CHRM2 were equally targeted by six herbs and identified as viral myocarditis-associated symbols. …”
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The Succession of Cervical Canal Microbiota in Endometrial Cancer and Cervical Cancer: A Clinical Metagenomics Study by Lei S, Wang J, Zhang M, Huang J, Liu Y, Long Y, Xing Y, Yu Z

“…Shibo Lei,1,2,* Jing Wang,1,* Man Zhang,2 Jing Huang,3 Ying Liu,1 Ying Long,1 Yixuan Xing,4 Zheng Yu2 1The Affiliated Cancer Hospital of Xiangya School of Medicine/Hunan Cancer Hospital, Central South University, Changsha, People’s Republic of China; 2Human Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, People’s Republic of China; 3Department of Parasitology, School of Basic Medical Science, Central South University, Changsha, People’s Republic of China; 4The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yixuan Xing, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, People’s Republic of China, Email 234428043@qq.com Zheng Yu, Human Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, People’s Republic of China, Email yuzheng@csu.edu.cnObjective: To define stage-specific cervical canal microbiota signatures across the continuum of gynecologic malignancies from benign endometrial cancer (BE)/cervical cancer precancerous lesions (CIN) to endometrial cancer (EC)/cervical cancers (CC), and to evaluate their potential as diagnostic biomarkers and therapeutic targets.Methods: In the observational study, metagenomic sequencing was employed to investigate the cervical canal microbiota of 45 patients, including BE, EC, CIN, and CC. …”
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Interplay of education and community norms in justifying intimate partner violence among ever-married women aged 15–49 years in Bangladesh: a cross-sectional study by Mohammad Hridoy Patwary, Sumaiya Nusrat Esha

“…This study examines the interplay between education and community norms in shaping the attitudes toward IPV among ever-married women aged 15 to 49 in Bangladesh. Methods This study utilized data from the 2022 Bangladesh Demographic and Health Survey (BDHS). …”
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Prevalence and Associated Factors of Depression in Patients with Ischaemic Stroke: A Cross-Sectional Study by Li Y, Qin W, Chen Y, Zhang D, Zhao Y

“…Yifan Li,1,* Wei Qin,1,* Yitong Chen,2 Dongli Zhang,1 Yongchen Zhao1 1Department of Integrative Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding, Hebei, People’s Republic of China; 2Clinical Specialty of Integrated Chinese and Western Medicine, Hebei University, Baoding, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongli Zhang; Yongchen Zhao, Department of Integrative Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding City, Hebei Province, 071000, People’s Republic of China, Tel +86 0312 5981919, Email zhang_dongli@yeah.net; zhaoyongchen69@outlook.comObjective: To investigate the prevalence and severity of depression in patients with ischaemic stroke and identify its associated factors using a cross-sectional design over a 6-month period.Methods: This cross-sectional study included 499 patients with ischaemic stroke who met the diagnostic and inclusion criteria. …”
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Expert consensus on implementing patient-reported outcomes in telehealth: findings from an international Delphi study by Elizabeth J. Unni, Liv Marit Valen Schougaard, Olalekan Lee Aiyegbusi, Kedar K. V. Mate, Elizabeth J. Austin, Klara Greffin, Natasha Roberts, Birgith Engelst Grove, Holger Muehlan, ISOQOL Clinical practice SIG PROs in Telehealth Working Group

“…This study aimed to generate expert consensus on the utilization of PROs in telehealth. Methods Delphi methodology was used to achieve consensus among international experts with a predetermined consensus threshold of 70%. …”
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Isolation and Characterization of a Novel Lytic Phage N22 and Its Effect on Drug-Resistant Klebsiella Pneumoniae by Liu D, Qin K, Hong C, Huang W, Li W, Lian P, Li M, Chen H, Liu X

“…This study aimed to address the multidrug resistance crisis in intensive care units by exploring the use of ceftazidime/avibactam (CAZ/AVI), a widely used clinical antimicrobial agent, in conjunction with phage therapy.Materials and Methods: We screened a clinical strain of KP from ICU and successfully isolated phage N22 from hospital wastewater. …”
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Institutional Factors Influencing Student Performance in Management of Second Stage of Labour in Kakamega County Hospitals, Kenya by George Lipesa, John Okath, Damaris Ochanda

“…Aim: The study's precise goal was to assess institutional factors influencing student performance in managing the second stage of labour in Kakamega County hospitals, Kenya. Methods: The study employed an analytical cross-sectional research design using a quantitative data collection approach. …”
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