High Humidity Alters Myeloid-Derived Suppressor Cells in Spleen Tissue: Insights into Rheumatoid Arthritis Progression by Wang H, Wang M, Wang T, Li X, Wen C, He Z, Huang L

“…Furthermore, there is a lack of evidence linking humidity to the worsening of RA symptoms in animal models.Methods: The Collagen-induced arthritis (CIA) mouse model was established using C57BL/6 mice. …”
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Change of the elasticity COEFFICIENT of the walls of the common carotid artery as a predictor of adverse cardiovascular events in hypertensive patients after ischemic hemispheric s... by O. A. Lisovaya

“…The most optimal predictive value is the cutoff point of distensibility coefficient is equal to 27.05 kPa (AUC=0.847±0.038; 95% CI =0,774-0,921; sensitivity =90.6%, specificity=70.6%). …”
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Effect of Exercise and Nutrition Intervention for Older Adults with Impaired Physical Function with Preserved Muscle Mass (Functional Sarcopenia): A Randomized Controlled Trial by Ji S, Baek JY, Go J, Lee CK, Yu SS, Lee E, Jung HW, Jang IY

“…The effectiveness of a program combining exercise and nutritional support—known interventions for individuals with low muscle mass—was evaluated for its impact on older adults with functional sarcopenia.Methods: An unblinded, parallel-group randomized controlled trial was conducted in a public medical center in a rural Korean community. …”
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Evaluation of the Diagnosis Accuracy of the AWGS 2019 Criteria for “Possible Sarcopenia” in Thai Community-Dwelling Older Adults by Adulkasem N, Vanitcharoenkul E, Chotiyarnwong P, Asavamongkolkul A, Unnanuntana A

“…Our secondary aim was to explore the use of adjunct variables to improve the diagnostic accuracy of the “possible sarcopenia” criteria for detecting sarcopenia.Methods: This study is a secondary analysis of an epidemiological investigation of the prevalence of sarcopenia among Thai older adults that was conducted during 2021– 2022. …”
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Sanming Model of Medical Service Integration: Impact on Medical Expenditures, Service Provision, and Resource Allocation in China by Lin K, Liu X, Xiang L, Luo F

“…This study evaluates the model’s impact on medical expenditures, service provision, and resource allocation.Methods: We conducted an interrupted time series analysis on outcome variables related to medical expenditures, service provision, and resource allocation in Sanming City. …”
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Microleakage of high viscosity glass-ionomer and glass-carbomer with and without coating before and after hydrothermal aging by Asli Patır Münevveroğlu, Alev Ozsoy, beyza ballı akgol, ruhan bozatlioglu, pelin korkut, busra uysal, Mutlu Ozcan

“… Objective: The objective of this study was to evaluate the microleakage patterns of GIC and GGC with and without their protective surface coatings on enamel and dentin margins before and after aging. Material and Methods: Two rectangular cavities (height: 2 mm; width: 3 mm; depth: 1.5 mm) were prepared on each tooth at the cemento-enamel junction were prepared on human permanent molars (N=56) and the teeth were randomly assigned to be restored with one of the following: a) high viscosity glass-ionomer cement (GIC) (EQUIA Fil, C Corp., Tokyo, Japan) (n=28), b) glass-carbomer cement (GCC) (Glass Carbomer Products, Leiden, The Netherlands) (n=28). …”
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Clinical Significance of Abnormal Serum LGALS3BP Expression in Patients with Idiopathic Inflammatory Myopathies by Huang L, Huang X, Zhou W, Jiang Y, Zhu H, Lao Y, Deng Z, Tang Y, Wang J, Li X

“…The correlation between serum LGALS3BP levels, clinical features, and inflammatory markers in patients with IIM was also assessed.Methods: Based on the Gene Expression Omnibus (GEO) database, we used bioinformatics analysis to screen for overlapping extracellular protein-differentially expressed genes between any two groups of DM, ASS, IMNM, and healthy controls (HCs). …”
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Decoding Drug Interactions: Character and Degree of Pharmacokinetic Interactions Between Telmisartan and Sorafenib or Donafenib in Rats by Li Y, Du W, Shan C, Yu Z, An J, Dong Z

“…Therefore, this study aimed to evaluate these pharmacokinetic interactions in male Sprague-Dawley (SD) rats.Methods: The animals were divided into seven groups (n = 6) and treated with sorafenib, donafenib, or telmisartan as monotherapy (groups I–III), multi-dose sorafenib or donafenib with single dose telmisartan (groups IV and V), or multi-dose telmisartan with single dose sorafenib or donafenib (groups VI and VII). …”
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Study on the spatial and temporal differences and influencing factors of out-of-pocket payments as a share of total health expenditure in China by Xiaoyu Dong, Huaizhi Cheng, Ruotong Tian, Lingxiao Gao, Wenpei Lyu, Jiaqi Zhang, Doudou Huang, Bin Guo

“…However, in China, research in this area is relatively scarce, and few studies have been conducted from a macro perspective and space-time dimension. Methods Based on the panel data of 31 provinces in China, the spatiotemporal distribution characteristics of the proportion of OOP payments in China from 2013 to 2022 were analyzed using spatial autocorrelation. …”
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Correlational Analysis of Resistant Hypertension with Diabetes Mellitus, Chronic Kidney Disease, and the Interplay of Sodium, Calcium, Magnesium, and Phosphorus by Feng XD, Wang SF, Qiao SY, Huang JY, Ma ZL, Zhou D, Tang JY, Wei YH

“…Xin-Di Feng,1,* Shao-Feng Wang,2,* Si-Yu Qiao,1 Jia-Ying Huang,3 Zi-Lin Ma,1 Duan Zhou,1 Jing-Yi Tang,3 Yi-Hong Wei1 1Department of Cardiovascular, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of Traditional Chinese Medicine, Chuansha Huaxia Community Health Service Center, Shanghai, People’s Republic of China; 3Department of Industry-university Cooperative Research Center, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing-Yi Tang, Department of Industry-university cooperative research Center, Shanghai University of Traditional Chinese Medicine, No. 1200, Cailun Road, Pudong New District, Shanghai, 201203, People’s Republic of China, Tel +86-13601815342, Email dr_tang@163.com Yi-Hong Wei, Department of Cardiovascular, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No. 725, Wanping South Road, Xuhui District, Shanghai, 200032, People’s Republic of China, Tel +86-13801686228, Email tcmwyhdoc@163.comObjective: To analyze the relationship between resistant hypertension (RH) and hypertension, diabetes mellitus, chronic kidney disease, sodium, calcium, magnesium, phosphorus.Methods: A total of 475 patients with hypertension admitted to Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from January 2021 to December 2023 were divided into hypertension group (HT group) and resistant hypertension group (RH group). …”
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Comparison of the Dural Puncture Epidural and Conventional Epidural Analgesia Maintained Using Programmed Epidural Boluses for Labor Analgesia by Mo X, Yu J, Qin Z, Ma J, Chen Y, Chen X

“…We hypothesized that DPE, when combined with PIEB, not only speeds up analgesia onset but also improves neuraxial analgesia maintenance over EP.Patients and Methods: A total of 126 term nulliparous women with singleton pregnancies with a VAS pain score > 50 mm and cervical dilation < 5 cm were randomized to receive EP+PIEB or DPE+PIEB for labor analgesia, initiated with 15 mL of 0.0625% ropivacaine with 0.4 μg/mL of sufentanil using the EP or DPE technique (using 25-gauge Whitacre needle) technique and both maintained with the same solution for PIEB (fixed volume 10 mL, intervals 45 minutes, lockout interval 15 minutes) with labor analgesia. …”
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Determining the 90% Effective Dose of Remimazolam to Prevent Physical Movement in Surgical Abortions: A Biased-Coin Up-and-Down Sequential Allocation Trial by Fang F, Li H, Li L, Yan B, Yin P, Hu B, Zhu S, Kang X

“…However, its dosing references from clinical studies such as gastrointestinal and bronchoscopic anesthesia have resulted in high incidence of physical movement.Purpose: Determining the optimal dosage (the 90% effective dose [ED90]) for preventing physical movement during surgical abortions.Patients and Methods: Fifty-seven individuals aged 18 to 45 undergoing surgical abortion were included. …”
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Prognostic Value of Red Blood Cell Width Distribution-to-Platelet Ratio in Patients with Snakebite-Associated Multiple Organ Dysfunction Syndrome: A Retrospective Observational Stu... by Liang X, Xing D, Zhuang Z, Feng H, Li S, Fang X, Wang F, Qiu L, Chen XL

“…This study aims to explore the prognostic value of red blood cell distribution width (RDW) to platelet ratio (RPR) on multi-organ dysfunction (MODS) in patients with snake bites.Methods: A retrospective study included 637 patients with snakebite between 2015 and 2020 from two hospitals in Anhui province, China. …”
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Assessment of Dual Rinse Combined with Sodium Hypochlorite Irrigating Solution on Post-Instrumentation Pain and Bacterial Load Reduction: A Randomized Clinical Trial by Laila Zakaria Ismail Abdel-Hamid, Randa Mohamed El Boghdadi, Shaimaa Ismail Gawdat, Sherifa Tarek Salem, Noha Salah Soliman

“… Objective: The study compared the efficacy of Dual Rinse combined with sodium hypochlorite in comparison to sodium hypochlorite irrigating solution on post instrumentation pain incidence, reduction of the load of intracanal bacteria and periapical MMP-9 expression in patients with pulp necrosis. Material and Methods: Thirty-four patients diagnosed with a necrotic mandibular premolar having a single root canal were included. …”
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Tranexamic acid and tourniquet versus tourniquet for controlling blood loss during open abdominal myomectomy: a double-blind placebo-controlled randomised trial by George U Eleje, Kingsley E Ekwuazi, Victor I Amulu, Joseph T Enebe, Cyril C Dim, David M Aqua, Chidinma C Okafor, Chigozie G Okafor

“…Objectives To compare blood loss in reproductive-age women who received intravenous tranexamic acid plus tourniquet versus tourniquet and placebo during an open abdominal myomectomy.Methods This is a prospective three-centre double-blind randomised placebo-controlled trial of consenting eligible 114 women with uterine fibroids scheduled for open abdominal myomectomy. …”
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LncRNA PVT1 Promotes the Progress of Hypertrophic Scar via Regulating the Proliferation and Migration of Myofibroblasts Through Targeting miR-29a-3p/STAT3 by Han P, Liu R, Guan X

“…This research was aimed at exploring the clinical value of lncRNA PVT1 in HS formation and its potential mechanisms in human hyperplastic scar myofibroblasts (HSFs).Patients and Methods: Fifty-seven HS patients were enrolled. RT-qPCR was conducted to examine the RNA levels of lncRNA PVT1, miR-29a-3p and STAT3. …”
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Vaccarin Ameliorates Renal Fibrosis by Inhibiting Ferroptosis via Nrf2/SLC7A11/GPX4 Signaling Pathway by Cui M, Xu Q, Duan L, Lu J, Hu J

“…This study aimed to investigate the effects of vaccarin on RF and its molecular mechanisms.Methods: Network pharmacology was used to analyze the effect of vaccarin on RF, and molecular docking and molecular dynamics simulations were performed to assess the binding of nuclear factor erythroid 2-related factor 2 (Nrf2) to vaccarin. …”
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Development of Hybrid District Heating Systems by A. V. Sednin, K. M. Dyussenov

“…The issue of using electricity in district heating systems as an excess resource of integrated energy systems within the framework of equalizing the daily and seasonal schedule of energy consumption is also considered. …”
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The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma by Erdoglija Milan, Grgurević Uglješa, Cerović Snežana, Jović Milena, Baletić Nenad, Sotirović Jelena

“…This research should influence further studying of etiology and development of acquired middle ear cholesteatoma. Methods. We investigated clinical, histological and immunohistochemical characteristics of cholesteatoma in 50 samples from operated patients with acquired middle ear cholesteatomas. …”
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Runoff Variations and Quantitative Analysis in the Qinghai Lake Basin Under Changing Environments by Li Mo, Xinxiao Yu, Yonghan Feng, Tao Jiang

“…Abrupt changes were detected using the Mann–Kendall and cumulative anomaly methods, while the Budyko framework attributed runoff variations to dominant factors. …”
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