Boosting Hydroxyl Radical Generation with Nitrogen Vacancy–Modified Carbon Nitride for Triggering Dual Damage of Cancer Nucleus DNA–Mitochondria against Hypoxic... by Zhang Y, Liu M, Xue S, Li N, Hong J, Gu J, Ren X, Li H, Xu J, Zhang C, Liang T, Zhao B, Wang X

“…A hypoxic tumor microenvironment is the bottleneck of photodynamic therapy (PDT) and significantly weakens overall therapeutic efficacy.Methods: In this study, we introduce nitrogen vacancy–modified PCN (NV-PCN), a novel metal-free and O2-independent photosensitizer designed for PDT. …”
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Estimating the risk of zoonotic transmission of swine influenza A variant during agricultural fairs in the United States: a mathematical modeling by Dana C. Pittman Ratterree, Sapna Chitlapilly Dass, Martial L. Ndeffo-Mbah, Martial L. Ndeffo-Mbah

“…We investigate the transmissibility of influenza A variant from pigs to humans using epidemiological data from a 2011 zoonotic outbreak of an influenza H3N2 variant during an agricultural county fair in Pennsylvania.MethodsWe developed a mathematical model for the transmission of a swine influenza pathogen among pigs and humans at an agricultural fair. …”
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Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review by Leqing Zhou, Chuyang Huang, Sheng Sun, Keping Ning, Shan Tang

“…We aim to conduct a systematic review and meta-analysis comparing the long-term oncologic and renal function outcomes of KSS with those of radical nephroureterectomy (RNU) for UTUC.Materials and methodsA literature search was conducted on PubMed, Embase, and Web of Science in January 2024. …”
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Digital mapping of Ghana’s soil properties and nutrients: performance of spline and weighted average approaches by Kora B.D. Simperegui, Anselme K.K. Kouame, Benjamin Kwesie, Prem S. Bindraban, William Adzawla, Eric Asamoah, Mohamed El Gharous

“…This involved two profile data harmonization methods—equal-area spline and thickness-weighted average—with a quantile random forest model. …”
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Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain by Chen Y, Tang G, Lu J, Tang S, Xiong X, Chen C, Pei L, Shi J

“…This study aims to clarify the mechanism of C/EBP-β regulating TGF-β 1 mediated spinal astrocyte A1/A2 polarization in the neuropathic pain caused by vincristine.Methods: Neuropathic pain model was established in rats by intraperitoneal injection of Vincristine (VCR). …”
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Glaucoma Home Monitoring Using Online Circular Contrast Perimetry Over 6 Months: Performance and Patient Attitudes in the Developing World Setting by Hoang TT, Mai TQ, Pham DT, Nguyen XT, Nguyen DA, Vu DT, Hoang HT, Skalicky SE

“…This study assessed the longitudinal performance and user feedback of home OCCP in an Asian population.Methods: Twenty glaucoma and fifteen healthy participants underwent a comprehensive ocular examination and visual field tests in clinic, using OCCP and standard automated perimetry. …”
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The interplay between home and job demands, resources, and the intention to stay in nursing: A cross-sectional study by Jasperina Brouwer, Stéfanie André, Nienke Renting

“…Background: Concerns about the global nursing shortage highlight that, while increasing graduates is considered as essential, addressing retention issues is equally critical to mitigate the shortage effectively. …”
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Knowledge, Attitude, and Belief of Healthcare Professionals Toward Obesity Stigmatization by Lang H, Zhang X, Yan N, Du J, Jiang X

“…This study aimed to investigate healthcare professionals’ knowledge about obesity-related health impacts, attitudes regarding weight bias (negative or discriminatory attitudes toward individuals with obesity), and beliefs about the causes and nature of obesity.Methods: This cross-sectional study was conducted among healthcare professionals between Jan, 2024 and Feb, 2024 in The Department of General Medicine, Chengdu Second People’s Hospital, using a self-designed questionnaire.Results: A total of 388 valid questionnaires [303 (78.09%) female and a mean age of 37.71 ± 8.46 years] were included. …”
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From Gene to Intervention: NLRC4 and WIPI1 Regulate Septic Acute Lung Injury Through Autophagy by Yang X, Sun Z, Liu Z, Chen H, Fang Y, Tao W, Zhao N, Ouyang X, Liu F, Qian K

“…Although autophagy is crucially involved in the inflammatory response, its precise molecular mechanisms in SALI remain unclear, forming the basis of this study.Methods: Herein, two microarray datasets (GSE33118 and GSE131761) and three single-cell sequencing datasets (SCP43, SCP548, and SCP2156) derived from human samples were used to ascertain the interrelationship between Differentially Expressed Autophagy-Related Genes (DEARGs) and SALI. …”
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The allocation and fairness of hospital pharmacist human resources in China: a time-series study by Hengfan Ni, Ma Yuan, Peng Wan, Qiu Xiang, Du Hongling, Tang Minghai, Li Jian

“…The study aims to analyze the supply and demand of pharmacist human resources in Chinese healthcare institutions and evaluate the equity of their distribution to provide a reference for the rational management of pharmacist resources. Methods This was a time-series study that was conducted using data obtained from Health and Health Statistical Yearbook that is performed every year by the National Health Commission of the People’s Republic of China. …”
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Ultrasonic Parameters as Biomarkers for Tumor Staging and Aggressiveness in Breast Cancer: Correlation with GP73 and miR-27a by Tao ZY, Rong R, Zhou LP

“…Zi-Yu Tao,1,* Rong Rong,2,* Lei-Ping Zhou3 1Obstetrics and Gynecology Hospital Fudan University, Shanghai, 200233, People’s Republic of China; 2Department of Clinical Laboratory, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, 230000, People’s Republic of China; 3Department of Ultrasound, International Peace Maternity and Child Health Hospital, Shaghai, 200063, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei-Ping Zhou, Department of Ultrasound, International Peace Maternity and Child Health Hospital, Shaghai, 200063, People’s Republic of China, Tel +86-13761708810, Email Zhouleiping68@163.comObjective: To investigate correlations between CEUS parameters and serum GP73/miR-27a in breast cancer.Methods: In the study, 117 highly suspected breast cancer diagnosed and treated in our hospital during March 2022 to April 2024 were included. …”
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SEMAGLUTIDE: Weight loss, glycaemic control and safety profile in obese patients with and without type-II diabetes-An experience from Karachi, Pakistan by Muhammad Y. Memon, Tasnim Ahsan, Rukhshanda Jabeen, Saba Latif, Saeeda F. Qasim, Paras Imran

“…Objective To assess the efficacy and safety of Semaglutide (a GLP-1 receptor agonist) in obese patients with and without Type-II Diabetes Mellitus. Methods This observational analytic cohort study was conducted in a private medical institute in Karachi Pakistan; from August 2022 to January 2023. …”
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Comparing the Prognostic Value of Lactate to the Neutrophil to Lymphocyte Ratio Among Sepsis Patients: A Prospective Cohort Study by Bou Chebl R, Haidar S, Kattouf N, Assaf M, Alwan JS, Khamis MM, Abdeldaem K, Makki M, Tamim H, Abou Dagher G

“…This study compares the prognostic value of lactate and NLR in septic patients.Methods: This prospective cohort study included 874 adult septic or septic shock patients presenting to a tertiary care center’s Emergency Department between September 2018 and February 2021. …”
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Alkannin Induces G2/M-Phase Arrest, Apoptosis, and Inhibition of Invasion by Targeting GSK3β in Esophageal Squamous Cell Carcinoma by Ma H, Xu P, Jia Y, Zhou Y, Li X, Wang Y, Ma K

“…This study aims to investigate the therapeutic effects of Alkannin on ESCC and elucidate its potential targets and molecular mechanisms.Methods: Cell Counting Kit-8 (CCK-8) assays, colony formation assays, Hoechst 33342 staining, wound healing assays, Transwell migration assays, flow cytometry, and Western blotting were used to investigate the therapeutic effects of Alkannin on ESCC in vitro. …”
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Analysis of Electroacupuncture Parameters for Irritable Bowel Syndrome: A Data Mining Approach by Tang Y, Tang X, Wen Q

“…This study endeavors to identify effective EA parameters for IBS through data mining methodologies.Methods: To retrieve randomized controlled trials (RCTs) on EA for IBS published between 2013 and 2024, a comprehensive search was conducted across nine databases. …”
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MDT Reduces Perioperative Thrombotic Events in Elderly Orthopedic Patients by Chen T, Lei X, Tian J, Mai H, Yu Y, Wu W, Wen L, Saw PE, Zhang M

“…Tonghua Chen,1,* Xiaojun Lei,1,* Jingwei Tian,1,* Haochen Mai,1 Yuanfang Yu,1 Wenxia Wu,1 Liqiang Wen,1 Phei Er Saw,1 Meng Zhang1,2 1Department of General Practice, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 2Department of General Practice, Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Shanwei, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Phei Er Saw; Meng Zhang, Email caipeie@mail.sysu.edu.cn; zhangm7@mail.sysu.edu.cnPurpose: To minimize the occurrence of acute thromboembolic events in elderly patients during the perioperative period and prevent adverse clinical outcomes, this study explores an efficient, and precise approach to the formulation of antithrombotic regimens under a multidisciplinary team (MDT) consultation model.Patients and Methods: This single-center retrospective study included elderly patients on long-term antithrombotic therapy who underwent orthopedic surgery in our hospital between January 2019 and May 2023. …”
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The Effects of HFOV-VG vs HFOV on Bronchopulmonary Dysplasia and Neurobehavioral Development in Preterm Infants with Perinatal Acute Respiratory Distress Syndrome by Tao M, Yan L, Hu Y, Shen L, Cai N

“…Min Tao,* Ling Yan,* Yuan Hu, Leilei Shen, Na Cai Department of Pediatrics, The First Hospital Affiliated to Army Medical University, Chongqing, 400038, People’s Republic of China*These authors contributed equally to this workCorrespondence: Na Cai, Department of Pediatrics, The First Hospital Affiliated to Army Medical University, No. 30, Gaotanyan Street, Chongqing, 400038, People’s Republic of China, Tel +86-23-68766213, Email caina@tmmu.edu.cnObjective: This study aimed to explore whether high-frequency oscillatory ventilation with volume-guarantee (HFOV-VG) strategy could reduce the incidence of bronchopulmonary dysplasia (BPD) and improve poor neurological prognosis in premature infants with perinatal acute respiratory distress syndrome (NARDS) compared with high-frequency oscillatory ventilation (HFOV) alone.Methods: This retrospective single-center study conducted in the neonatal intensive care unit (NICU) from January 2016 and December 2023. …”
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Robotic-assisted versus conventional hip arthroplasty: a comparative analysis of perioperative blood management and early outcomes by Annapareddy Adarsh, Jayakumar Tarun, Reddy Manideep, Mulpur Praharsha, Gurram Vijay Kumar Reddy, Prasad Vemaganti Badri Narayana, Gurava Reddy A. V.

“…A total of 200 patients undergoing primary THA were equally divided into RATHA (using the MAKO SmartRobotics system) and CTHA cohorts. …”
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Machine Learning-Driven Prediction of One-Year Readmission in HFrEF Patients: The Key Role of Inflammation by Ma F, Hu Y, Han P, Qiu Y, Liu Y, Ren J

“…Predicting one-year readmission risk is crucial for optimizing treatment and reducing costs.Methods: We conducted a single-center retrospective study on adult HFrEF patients admitted to the Cardiovascular Department of the First Affiliated Hospital, Zhejiang University School of Medicine on January 2020 and March 2023. …”
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Biaxial Flexural Strength of High-Translucence Monolithic Ceramics upon Various Thicknesses by Niwut Juntavee, Apa Juntavee, Sirintana Phetpanompond

“…HTY-PSZ was stronger than ZLS, but each was equally strong for thickness in the range of 0.4–2.0 mm.…”
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