Associations of Leukocyte-Derived Chemotaxin-2 (LECT2) with Insulin Resistance and Metabolic Syndrome in Type 2 Diabetes: A Cross-Sectional Study by Sha Y, Lu J, Jin R, Li L, Zhang M

“…The results could offer fresh perspectives on the diagnosis and therapeutic strategies for T2D and associated metabolic disorders.Methods: A cross-sectional study was conducted on 148 T2D patients, including 90 with MetS and 58 without MetS. …”
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Comparative Analysis of Short-Term Outcomes in Thoracoscopic Minimally Invasive Versus Traditional Mitral Valve Replacement: Randomized Clinical Trial Study by Yusuf Shieba, Abd Elhalim Shalaby, Tamer Elbanna, Mohamed-Adel Elgamal, Ahmed El-minshawy

“…Objective: The aim of this research is to investigate the short-term outcomes of thoracoscopic minimally invasive mitral valve replacement in comparison with the conventional technique. Subjects and Methods: This study included 100 patients with isolated mitral valve disease, who were randomly divided into two equal groups. …”
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Stakeholders’ Perceptions of the Peer-to-Peer Energy Trading Model Using Blockchain Technology in Indonesia by Faisal Yusuf, Riri Fitri Sari, Purnomo Yusgiantoro, Tri Edhi Budhi Soesilo

“…The results of filling out the questionnaire were analyzed using four methods: IFE/EFE matrix; IE matrix; SWOT matrix; and SPACE matrix to assess the results and their suitability to each other. …”
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Effect of combination antihypertensive therapy, including renin-angiotensin-aldosterone system inhibitors, on oxidative stress and arterial remodeling in hypertensive patients with... by Z. M. Akhilgova, A. P. Roitman, N. G. Rakova, A. V. Bugrov, E. A. Pavlovskaya, M. S. Zastrozhin, A. G. Avtandilov

“…To study the effect of triple combination therapy on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction (HFpEF).Material and methods. The study involved 76 people with diagnosed HFpEF. …”
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Copper-Based Nanoparticles for Effective Treatment Against Sepsis-Induced Lung Injury in Mice Model by Li JM, Zhang L, Pei SL, Guo L, Shen HL, He J, Guo YY, Zhang WQ, Lin F

“…In this study, a novel class of ultrasmall nanoparticles (Cu4.5O USNPs) was developed to address sepsis-induced lung injury (SILI).Methods: The synthesized nanoparticles were thoroughly characterized to assess their properties. …”
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Non-Pharmaceutical Interventions on COVID-19 in Workers and Residents of Nursing Homes in Geneva: A Mixed Qualitative and Quantitative Study by Lakshmi Krishna Menon, Ania Wisniak, Simon Regard, Silvia Stringhini, Idris Guessous, Jean-François Balavoine, Omar Kherad, The SEROCoV-WORK + Study Group

“…Incident rate ratios (IRRs) were the calculated levels of NPI restrictiveness. Methods: We used a mixed methodology to identify factors that might have affected COVID-19 expansion in nursing homes in the canton of Geneva, Switzerland. …”
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Predicting Superaverage Length of Stay in COPD Patients with Hypercapnic Respiratory Failure Using Machine Learning by Zuo B, Jin L, Sun Z, Hu H, Yin Y, Yang S, Liu Z

“…This model is capable of predicting in advance whether an inpatient’s length of stay will exceed the average duration, thereby enhancing its clinical application and utility.Methods: The study included 568 COPD patients with hypercapnic respiratory failure, 426 inpatients from the Department of Respiratory and Critical Care Medicine of Yancheng First People’s Hospital in the modeling group and 142 inpatients from the Department of Respiratory and Critical Care Medicine of Jiangsu Provincial People’s Hospital in the external validation group. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…The high porosity of biomaterials induces more M2 macrophages, while the natural compound kaempferol inhibits the expression of matrix metalloproteinase 9 (MMP9) and thus inhibits the associated inflammatory and immunological responses.Methods: portable electrospinning dressings (PEDs) were prepared from the spinning solution using a portable electrospinning device. …”
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Research Progress of Liver Cancer Recurrence Based on Energy Metabolism of Liver Cancer Stem Cells by Wu M, Wang H, Wu X, Zeng H, Miao M, Song Y

“…Mingming Wu,1,2,* Huayu Wang,2,3,* Xiangxiang Wu,1,2 Huahui Zeng,1,2 Mingsan Miao,1,2 Yagang Song1,2 1Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 2Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Zhengzhou, Henan, 450046, People’s Republic of China; 3College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yagang Song, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China, Tel/Fax +86-0371-65962546, Email songyagang1016@163.comObjective: The aim of this study is to investigate the recurrence and progression of liver cancer by focusing on the energy metabolism of liver cancer stem cells.Methods: A comprehensive literature search was conducted using databases including CNKI, PubMed, Wanfang, and Citexs to analyze the etiology and treatment of hepatocellular carcinoma (HCC), the factors and mechanisms contributing to HCC recurrence, and the impact of energy metabolism in HCC stem cells on the development of HCC. …”
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LncRNA MALAT1/Calpain-1 Axis in ATO Induced hERG Channel Deficiency by Yan C, Li Y, Li X, Li Y, Zhang Y, Sun J, Ding Q, Zhao X, Li B

“…Furthermore, it sought to identify pharmacological agents that could mitigate the cardiotoxic effects of ATO and establish viable intervention targets for the prevention and management of acLQTS.Methods: First, we employed gene chip arrays to identify target long noncoding RNAs (lncRNAs). …”
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Glymphatic System Dysfunction in Elderly Patients with Late-Onset Epilepsy and Comorbid Chronic Insomnia Revealed by Diffusion Tensor Imaging Along the Perivascular Space (DTI-ALPS... by Wang Y, Hu J, Zhang YY, Wang FY, Wu JC, Wang L

“…Yu Wang,1,2,* Jie Hu,2,3,* Yue-Yu Zhang,2,3 Fu-Yu Wang,4 Jun-Cang Wu,2 Long Wang2 1Graduate School of Wan Nan Medical College, Wuhu, Anhui, 241002, People’s Republic of China; 2Department of Neurology, The Second People’s Hospital of Hefei, Hefei, Anhui, 230011, People’s Republic of China; 3The Fifth Clinical Medical College of Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China; 4Department of Pharmacy, The Second People’s Hospital of Hefei, Hefei, Anhui, 230011, People’s Republic of China*These authors contributed equally to this workCorrespondence: Long Wang, Department of Neurology, The Second People’s Hospital of Hefei, Hefei, Anhui, 230011, People’s Republic of China, Email guxindao606@126.comPurpose: This study assessed the influence of glymphatic system (GS) dysfunction on cognitive decline in patients with late-onset epilepsy (LOE) and comorbid chronic insomnia utilizing diffusion tensor imaging along the perivascular space (DTI-ALPS).Methods: Clinical data were collected from 42 elderly LOE patients, 17 with and 25 without chronic insomnia, as well as from 22 healthy controls (HCs) matched for age and sex. …”
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Opioid-Free versus Opioid-Sparing Anesthesia for Postoperative Pain and Early Recovery After Laparoscopic Cholecystectomy: A Randomized Controlled Trial by Xiong M, Liu Y, Liang Y, Wang H, Zhang L, Zhang Z, Fang M

“…This study compared the efficacy of OFA and OSA in managing postoperative pain and recovery after laparoscopic cholecystectomy (LC).Patients and Methods: A single-center, randomized controlled trial was conducted with 86 adults undergoing LC. …”
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Efficacy of external warming in attenuation of hypothermia in surgical patients by Zeba Snježana, Šurbatović Maja, Marjanović Milan, Jevđić Jasna, Hajduković Zoran, Karkalić Radovan, Jovanović Dalibor, Radaković Sonja

“…The aim of this study was to evaluate the efficiency of external warming system in alleviation of cold stress and hypothermia in patients who underwent major surgical procedures. Methods. The study was conducted in the Military Medical Academy in Belgrade. …”
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Construction of a Nomogram Model for Predicting Prognosis in Breast Cancer Patients Based on the Expression of THRSP and ACACA Proteins Tissues by Wei B, Li F, Yan H, Shen J

“…In addition, a nomogram model to predict the prognosis of breast cancer patients was constructed in this study.Methods: Retrospective analysis of 202 cases of breast cancer patients who underwent surgical treatment in our hospital from October 2019 to March 2021, and collection of patients’ cancer tissues and non-Tumor tissue specimens. …”
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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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The Prevalence, Characteristics, and Factors Associated with Chinese Herbal Medicine Use Among Chinese Middle-Aged and Older Adults with Chronic Lung Disease: A Cross-Sectional Stu... by Tian H, Zhu X, Liu H, Liao Y, Cui K, Liu J, Gong X

“…This study aims to examine the prevalence and influencing factors of CHM use among middle-aged Chinese patients with CLD.Patients and Methods: The data analyzed in this study were extracted from the China Health and Retirement Longitudinal Study in 2018. …”
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Study of the Chemical Composition and Anti-Inflammatory Mechanism of Shiyiwei Golden Pill Based on UPLC-Q-TOF/MS and Network Pharmacology by Han C, Chen J, Shen C, Liang Q, An Y, Zhou C, Liu K, Xia Q, He Q, Zhang H

“…This study aimed to investigate the chemical composition and anti-inflammatory effects of SYW, as well as its potential mechanisms.Methods: The components of SYW were identified using ultrahigh-performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS). …”
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Behavioral Changes During COVID-19 Omicron Variant Infection on Children with Autism Spectrum Disorder in China by Ye F, Hou X, Chen J, Qin H, Xu X, Liu D, Liu J, Sun Q, Liu H, Hu F, Zhou Y, Xu P, Zhang Q

“…Fang Ye,1,* Xiaonan Hou,1,* Jie Chen,1 Hui Qin,1 Xiaojing Xu,1 Die Liu,1 Jing Liu,2 Qi Sun,1 Haiyan Liu,3 Fang Hu,4 Yuwan Zhou,5 Pengfei Xu,1,* Qi Zhang1,* 1Department of Pediatrics, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 3Department of Pediatrics, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi an, People’s Republic of China; 4Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510623, People’s Republic of China; 5Department of Prevention Care, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Pengfei Xu; Qi Zhang, Department of Pediatrics, China-Japan Friendship Hospital, No. 2 East Yinghua Road, Chaoyang District, Beijing, 100029, People’s Republic of China, Email xpf@263.net; zhangqi0355@sina.comPurpose: The objective of this study was to investigate the behavioral changes in the core features and challenging behaviors of children with Autism Spectrum Disorder (ASD) during the COVID-19 Omicron wave (from December 2022 to January 2023) in China.Patients and Methods: A total of 515 caregivers of children with ASD completed an online survey. …”
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Prevalence and Molecular Characteristics of 16S rRNA Methylase Genes in Clinical Isolates of Carbapenem-Resistant Enterobacterales by Li C, Zhang F, Li G, Wang W

“…Caiyun Li,1,* Fa Zhang,1,* Gang Li,2,3 Wen Wang2,3 1Department of Clinical Laboratory, Nanjing Pukou People’s Hospital, Nanjing, 211800, People’s Republic of China; 2Center of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wen Wang, Email 42170662@qq.comObjective: To analyze the prevalence and molecular characteristics of 16S rRNA methylase genes in clinical isolates of carbapenem-resistant Enterobacterales, for clinical doctors provide a reference basis for the rational use of drugs.Methods: The Enterobacterales isolated from our hospital from 2020 to 2022 were selected and identified by VITEK 2 Compact automatic bacterial identification instrument. …”
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Assessing Racial and Gender Disparities in Asthma Education, Knowledge, and Healthcare Access Among Adolescents by Abballe A, Forman A, Jamet KE, Pant J

“…The goal is to identify gaps in asthma education and knowledge, as well as other barriers that may contribute to the underdiagnosis of asthma within these groups.Patients and Methods: This cross-sectional survey included adolescents aged 10– 18 years, with responses collected through Qualtrics. …”
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