Predictive Laboratory Markers for Gastrointestinal Complications in Children with Henoch-Schönlein Purpura by Guo Q, Xia S, Ding Y, Liu F

“…Identifying reliable predictive markers for GIS complications is crucial for early intervention and improved patient outcomes.Objective: This study aims to identify laboratory markers predictive of GIS complications in children with HSP using a machine learning approach.Methods: This retrospective study included children diagnosed with HSP and a control group from May 2020 to January 2024. …”
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COST-EFFECTIVENESS OF APIXABAN AS COMPARED WITH WARFARIN AND ACETYLSALICYLIC ACID IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION IN THE RUSSIAN FEDERATION by A. V. Rudakova, V. A. Parfenov

“…Over lifetime horizon apixaban as compared with warfarin and aspirin required additional treatment costs equal to 112.72 and 101.35 thousands rubles, respectively. …”
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Age at diagnosis of autism spectrum disorders: is there an association with socioeconomic status and family self-education about autism? by Hrdlicka M, Vacova M, Oslejskova H, Gondžová V, Vadlejchova I, Kocourkova J, Koutek J, Dudova I

“…Mothers were significantly more active in seeking information on autism than fathers or both parents equally (80 vs 9 vs 28 cases, respectively; P<0.001). …”
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Utilizing Targeted Next-Generation Sequencing for Rapid, Accurate, and Cost-Effective Pathogen Detection in Lower Respiratory Tract Infections by Qin L, Liang M, Song J, Chen P, Zhang S, Zhou Y, Li H, Tang J, Ma Y, Yang B, Xu J, Zhang J

“…Lisha Qin,1,* Mengyuan Liang,1,2,* Jianping Song,1,* Ping Chen,1,* Shujing Zhang,3,* Yaya Zhou,1 Hui Li,1 Jian Tang,1 Yanling Ma,1 Bohan Yang,1 Juanjuan Xu,1 Jianchu Zhang1 1Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Zhengzhou University People’s Hospital, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of China; 3Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianchu Zhang, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China, Tel +86-13971445469, Email zsn0928@163.comObjective: To evaluate the diagnostic performance and clinical impact of targeted next-generation sequencing (tNGS) in patients with suspected lower respiratory tract infections.Methods: Following propensity score matching, we compared the diagnostic performances of tNGS and metagenomic next-generation sequencing (mNGS). …”
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Risk Factors for Depression and Nomogram Prediction Among Chinese Coronary Heart Disease Patients: A Multi-Center Study from 2016 to 2018 by Tong H, Zhang J, Jiang L, Dong L, Hu J

“…Hongxuan Tong,1,* Jiale Zhang,1,* Lijie Jiang,1 Lei Dong,2 Jiatong Hu3 1Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, People’s Republic of China; 2Breast Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 3Acupuncture Department, Guang ‘anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongxuan Tong, Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, No. 16 Nanxiao Street of Dongzhimennei, Dongcheng District, Beijing, People’s Republic of China, Email Thongxuan1@163.com Jiatong Hu, Doctor, Acupuncture Department, Guang ‘anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiangge Street, Xicheng District, Beijing, People’s Republic of China, Email 13716031300@163.comBackground: This study aimed to assess the prevalence and identify risk factors associated with depression among coronary heart disease (CHD) patients at different stages in China.Methods: Conducted as a hospital-based, cross-sectional study across 48 hospitals in 23 provinces, the research spanned from October 2016 to April 2018. …”
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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…However, limited research has explored the diagnostic potential of SF IL-10 in chronic PJI patients.Objective: The study aimed to investigate the relationship between SF IL-10 and incidence of chronic PIJ, and to evaluate its diagnostic reliability.Design and Methods: We analyzed data from 137 patients who underwent revision surgery for aseptic loosening or chronic PJI between 2017 and 2019 in our hospital. …”
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Evaluation of ChatGPT-4 in detecting referable diabetic retinopathy using single fundus images by Owais Aftab, Hamza Khan, Brian L. VanderBeek, Drew Scoles, Benjamin J. Kim, Jonathan C. Tsui

“…Design: A cross-sectional study comparing ChatGPT-4′s versus retina specialists’ identification of more than mild DR (mtmDR) and vision-threatening DR (VTDR). Methods: Images in equal proportions of normal, mild, moderate, and severe nonproliferative DR (NPDR), proliferative DR (PDR), and blurry images with and without suspected PDR were presented to a panel of blinded retina specialists who identified images as readable or unreadable, and potentially as mtmDR or VTDR. …”
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Ocular Manifestations of Perinatal HIV Infection in Kenyan Children on HAART: A Cross-Sectional Comparative Study by Alisi L, Armentano M, Visioli G, Mingaine MS, Albanese GM, Lucchino L, Bruscolini A

“…This study aims to report the prevalence of ocular involvement in a cohort of children with perinatally acquired HIV.Methods: This cross-sectional study recruited 73 HIV-positive and 59 HIV-negative age-matched children in Kenya. …”
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Good governance: Challenges and opportunities of Iran\'s context in achieving sustainable health development by Azam Raoofi, Hajar Haghighi, Khatere Khanjankhani, Masoomeh Ggholami, Amirhossein Takian

“…Participation, accountability, rule of law, equity and equality, transparency, corruption control, effectiveness and efficiency are among the recurring components of governance in different models. …”
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Inclusion in the cancer patient pathway among cancer patients with and without pre-existing mental or substance use disorders: a nationwide register-based study by Ina H. Heiberg, Lise Balteskard, Bjarne K. Jacobsen, Jørgen G. Bramness, Ragnar Nesvåg, Kjell Magne Tveit, Anne Høye

“…Methods This population-based registry study included incident cancer patients aged 21–79 between 2015 and 2018 (n = 65,328). …”
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A Comparative Investigation on Clinical Characteristics in Pediatric Obstructive Sleep Apnea Based on Two Distinct Guidelines by Ji T, Long T, Li X, Xu Z, Zhao J, Wang G, Wang H, Li H, Zhang F, Zheng L, Wang S, Ni X

“…Tingting Ji,1,* Ting Long,1,* Xiaodan Li,1,* Zhifei Xu,2 Jing Zhao,1 Guixiang Wang,1 Hua Wang,1 Hongbin Li,1 Fengzhen Zhang,1 Li Zheng,1 Shengcai Wang,1 Xin Ni1,3 1Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China; 2Department of Respiratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China; 3Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Ni, Email nixin@bch.com.cn; Shengcai Wang, Email wsc820329@163.comObjective: To investigate the differences in assessment of clinical characteristics between children with obstructive sleep apnea (OSA) diagnosed according to the 2007 and 2020 guidelines and those without OSA, together with the relationships between polysomnography (PSG) parameters and cognitive tests scores in preschool and school-aged children with OSA.Methods: Eighty children were totally recruited and divided into OSA and non-OSA groups based on two distinct guidelines, with further subclassification into preschool and school-aged subgroups. …”
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Development and validation of a nomogram prediction model for factors influencing 131I-refractory Graves’ hyperthyroidism by Kehua Liao, Xiaojuan Wei, Yan Chen, Dongyun Meng, Shaozhou Mo, Zeyong Sun, Fengyang Song, Lu Lu, Wentan Huang

“…ObjectiveTo examine the factors influencing 131I-refractory Graves’ disease (GD) hyperthyroidism in patients, develop a nomogram prediction model, and conduct its validation.MethodsA total of 272 hyperthyroidism patients who received initial 131I treatment at our hospital from January 2021 to January 2022 were randomly selected. …”
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Exome sequencing in Nigerian children with early‐onset epilepsy syndromes by Ibitayo Abigail Ademuwagun, Yagoub Adam, Solomon Oladapo Rotimi, Steffen Syrbe, Maximilian Radtke, Julia Hentschel, Johannes R. Lemke, Ezekiel Adebiyi

“…Results Pathogenic variants were identified in 6 out of 22 individuals, equaling a diagnostic yield of 27.3% and comprising variants in BPTF, NAA15, SCN1A, TUBA1A and twice in CACNA1A. …”
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Banxia Gualou Xiebai Tang and Qishen Yiqi Dropping Pills Combined Therapy for Qi Deficiency, Phlegm, and Blood Stasis Syndrome in Post-PCI Coronary Heart Disease Patients by Fan M, Du L, Jiang W, Ding T, Yang X, Peng Z

“…Mingqiang Fan,1,* Li Du,1,* Wensheng Jiang,2 Tao Ding,1 Xiangxiang Yang,1 Zhengfei Peng1 1Department of Cardiovascular Medicine, Affiliated Hospital of Gansu Medical College, Pingliang, Gansu, 744000, People’s Republic of China; 2Department of Integrated Chinese and Western Medicine, Affiliated Hospital of Gansu Medical College, Pingliang, Gansu, 744000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingqiang Fan, Email fbz790@126.comObjective: To evaluate the effects of Banxia Gualou Xiebai Tang combined with Qishen Yiqi Dropping Pills on Qi deficiency, phlegm, and blood stasis syndrome in post-percutaneous coronary intervention (PCI) coronary heart disease (CHD) patients.Methods: A retrospective analysis was conducted on 100 post-PCI CHD patients with Qi deficiency, phlegm, and blood stasis syndrome treated from October 2022 to April 2024. …”
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Effect of Esketamine-Based Opioid-Sparing Anesthesia Protocol on the Quality of Early Recovery After Urological Surgery: A Randomized Clinical Trial by Qi Y, Li W, Ren Y, Sun J, Zhu Y, Wang L, Zhou M, Wang L

“…The present study explored the effect of the esketamine-based opioid-sparing anesthesia protocol on the quality of postoperative recovery in patients undergoing elective urological surgery.Patients and Methods: A randomized, double-blind, controlled clinical trial was adopted. …”
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Ant’s faunistic investigation (Hymenoptera:Formicidae) in Shiraz vicinity by Roshanak Torabi, Shahrokh Pashaei Rad, Mohammad Reza Shokri

“…Samples were collected equally in times and numbers in the spring, summer and fall season 2014. …”
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Wedelolactone Ameliorates Ischemic Stroke by Inhibiting Oxidative Damage and Ferroptosis via HIF-1α/SLC7A11/GPX4 Signaling by Tao X, Zhao M, Gao K, Zhang W, Xu D, Li W, Mu F, Lin R, Guo C, Li R, Wang J

“…However, the potential of Wel to improve ischemic stroke (IS) and the underlying mechanisms remain unclear.Methods: The middle cerebral artery occlusion and reperfusion (MCAO/R) and oxygen-glucose deprivation/reoxygenation (OGD/R) were established to evaluate the potential neuroprotective of Wel. …”
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Psychological rehabilitation of individuals with alcohol use disorder, drug addiction, gambling disorder, and codependency by Aidos Ibragim, Bakytgul Issatayeva, Kundyz Kuanzhanova, Almagul Mandykayeva, Aliya Mambetalina

“…Future policy initiatives should prioritize the development of therapist training programs and the implementation of evidence-based treatment methods. Moreover, the results emphasize the necessity for continuous post-treatment support to maintain long-term recovery and prevent relapse. …”
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Melatonin Activates KEAP1/NRF2/PTGS2 Pathway to Attenuate Hyperoxia-Driven Ferroptosis in Bronchopulmonary Dysplasia by Deng X, Xie A, Ye D, Ma Y, Bao Z, Xie Q, Luo Z, Wang R, Li H, Yu R

“…This study aimed to test the hypothesis that melatonin mitigates hyperoxia-induced BPD by inhibiting ferroptosis in alveolar epithelial cells, specifically through modulation of the KEAP1/NRF2/PTGS2 signaling pathway.Methods: Hyperoxia-induced MLE-12 cells and neonatal mice were used to establish BPD models. …”
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Intralesional Bleomycin in Periungual Warts: A Prospective Randomised Controlled Study by Kallolinee Samal, Nibedita Dixit, Srigopal Mohanty, Debjit Kar, Siddhartha Dash, Manoj Kumar Nayak

“…A total of 56 patients with PW were randomised equally by block randomisation into two groups: Group A and Group B. …”
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