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8361
Age-Specific Differences in Association Between Personality and Changes in Outing Behaviors During the COVID-19 Pandemic in Japan: Cross-Sectional Web-Based Questionnaire Survey
Published 2025-06-01“…Overall, 1236 participants were recruited, with an equal number of participants for each gender and 10-year age group. …”
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8362
A Clinical Risk Prediction Model for Depressive Disorders Based on Seven Machine Learning Algorithms
Published 2025-05-01“…Weifeng Jin,* Shuzi Chen,* Mengxia Wang,* Ping Lin Department of Medical Laboratory, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ping Lin, Email Linpingsun20000@aliyun.comObjective: To develop a clinical risk prediction model for depressive disorders using seven machine learning algorithms based on routine blood test indicators.Methods: A retrospective study was conducted, involving 284 patients with depressive disorders and 214 healthy controls recruited between January and October 2024. …”
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8363
Global Trends and Emerging Frontiers on Ovarian Endometriosis: A Bibliometric and Visualization Analysis
Published 2025-06-01“…This study aimed to explore the development of ovarian endometriosis via bibliometric analysis and to identify global trends and frontiers.Methods: We systematically reviewed all pertinent studies up to 2023 from the Web of Science Core Collection (WoSCC) were downloaded. …”
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8364
Assessing the quality and integrating the evidence and strength of recommendations in the guidelines for gastric precancerous lesions
Published 2025-02-01“…Regarding reporting quality, domains 1, 3, and 4 had mean reporting rates equal to or higher than 60%. The mean overall score for the recommendation quality was 19.11%. …”
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8365
Distinct Trajectories of Fatigue Among Families with Post-Intensive Care Syndrome
Published 2025-06-01“…Qiong Chen,1,* Yanjin Huang,2,* Limin Xu,1 Xiaomei Chen3 1Department of Intensive Care Medicine, Xiamen Haicang Hospital, Xiamen, Fujian, People’s Republic of China; 2Department of Nursing, Xiamen Haicang Hospital, Xiamen, Fujian, People’s Republic of China; 3Department of Pain, Xiamen Haicang Hospital, Xiamen, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiong Chen, Department of Intensive Care Medicine, Xiamen Haicang Hospital, No. 89 haiyu Road, Haicang District, Xiamen, Fujian, 361026, People’s Republic of China, Tel +86 177 50612461, Email chenqiongfff@163.comPurpose: This study investigated the trajectories of fatigue symptoms in post-intensive care syndrome among family members (PICS-F) and aimed to explore the sociodemographic and clinical factors related to these trajectories.Patients and Methods: This was a longitudinal observational study conducted in an intensive care unit (ICU) of a tertiary hospital in Xiamen, China. …”
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8366
Demographic profile and trend in burn injury: A clinical study in South Karnataka
Published 2025-01-01“…Results: The age group involved was mostly from 0 to 10 years and accounted for 27.4%. Almost equal representation in male and female sex. The cause of burns was mostly thermal burns. …”
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8367
Prevalence and factors associated with preventable drug-related emergency department visits (DRED p ) in elderly patients
Published 2024-10-01“…This study investigates the prevalence of preventable drug-related ED visits (DRED p ) and the characteristics of DRPs in elderly ED patients through a comprehensive medication review. Methods A cross-sectional study was conducted at a non-trauma ED of a university-affiliated tertiary-care hospital. …”
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8368
Low-Density Lipoprotein Cholesterol as a Protective Factor in COPD and Implications for Statin Therapy: A Multi-Omics Genetic Epidemiology Study
Published 2025-07-01“…This study aimed to explore the association between low-density lipoprotein cholesterol (LDL-C) and COPD, as well as the impact of statin drugs on the progression of COPD.Methods: Employing an integrated approach that encompasses observational studies, genetic epidemiology, and molecular biology, this research investigated the link between LDL-C and COPD using clinical survey data, genome-wide association study (GWAS) data, and transcriptomic data. …”
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8369
The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis
Published 2025-01-01“…Building upon previous research on the immunological and inflammatory aspects of JDM, this study aims to investigate the role of pyroptosis in the pathogenesis of JDM using a comprehensive bioinformatics approach.Methods: Two microarray datasets (GSE3307 and GSE11971) were obtained from the Gene Expression Omnibus database, and a list of 62 pyroptosis-related genes was compiled. …”
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8370
Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis
Published 2025-04-01“…This study aimed to investigate gene expression changes related to myocardial aging in sepsis.Methods: Transcriptomic datasets (GSE79962 and GSE141864) were analyzed to identify senescence-related genes (SRGs) by intersecting differentially expressed genes (DEGs) with the CellAge database. …”
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8371
Decomposing socioeconomic differences in self-rated health and healthcare expenditure by chronic conditions and social determinants
Published 2025-05-01“…This study identifies which chronic conditions and social determinants contribute most to socioeconomic differences in self-rated health and healthcare expenditure. Methods Registry and survey data combining 3 socioeconomic indicators (income, education, and financial welfare), 26 social determinants, 20 chronic conditions, age, sex, self-rated health, and healthcare expenditure for 135,183 Dutch individuals aged 25–65, were linked at individual level. …”
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8372
A Bibliometric Analysis of the WoSCC Literature on the Use of Selective Serotonin Reuptake Inhibitors as Antidepressants
Published 2024-11-01“…Therefore, we conducted a bibliometric analysis to explore the research patterns surrounding SSRIs for depression, aiming to gain a deeper understanding of their development and impact.Methods: Publications about the use of SSRIs for the treatment of depression were identified in the Web of Science Core Collection. …”
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8373
Experiences of Individually Tailored Internet-Based Cognitive Behavioral Therapy During the COVID-19 Pandemic: Qualitative Interview Study
Published 2025-06-01“…ObjectiveThis qualitative study aimed to investigate the experiences of participants undergoing individually tailored ICBT with weekly therapist support during the COVID-19 pandemic. MethodsWe approached trial participants who had received ICBT for psychological symptoms related to the COVID-19 pandemic during the summer of 2020. …”
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8374
Clinical and Molecular Insights Into Anti-MDA5 Antibody-Positive Dermatomyositis: A Single-Center Retrospective and Transcriptomic Study
Published 2025-08-01“…Yunli Ren,1,* Tianqi Wu,2,* Weiwei Shi3,4 1Department of Rheumatology and Immunology, Affiliated Hospital 2 of Nantong University, Nantong, People’s Republic of China; 2School of Medicine, Nantong University, Nantong, People’s Republic of China; 3Department of Dermatology, Affiliated Hospital 2 of Nantong University, Nantong, People’s Republic of China; 4Department of Dermatology, The Third Affiliated Hospital of Soochow University, Changzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weiwei Shi, Department of Dermatology, Affiliated Hospital 2 of Nantong University, No. 666,Shengli Road, Nantong, 226000, People’s Republic of China, Email youzhi_gg@126.comObjective: To comprehensively characterize clinical features, diagnostic challenges, and prognostic biomarkers of anti-MDA5 antibody-positive dermatomyositis (MDA5-DM), incorporating transcriptomic analysis to elucidate underlying molecular mechanisms.Methods: We conducted a retrospective analysis of 29 MDA5-DM patients, collecting detailed clinical and laboratory data. …”
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8375
The Radiosensitizing Effect of Tumor-Derived Microparticles Co-Loaded with Sorafenib and Gold Nanoparticles on Hepatocellular Carcinoma
Published 2025-04-01“…In this study, we introduce a novel approach for treating HCC using tumor cell-derived microparticles (MPs) co-loaded with sorafenib and gold nanoparticles (AuNP) in combination with radiotherapy.Methods: MPSF@AuNP was prepared by co-incubating AuNP with sorafenib, and was evaluated using dynamic light scattering (DLS), transmission electron microscopy (TEM), ultraviolet-visible spectrophotometry (UV-Vis), inductively coupled plasma optical emission spectrometry (ICP-OES), high-performance liquid chromatography (HPLC), and SDS-PAGE electrophoresis. …”
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8376
Polyallylamine Hydrochloride-Modified Bovine Serum Albumin Nanoparticles Loaded with α-Solanine for Chemotherapy of Pancreatic Cancer
Published 2025-04-01“…To address these issues, this study developed a nanoparticle delivery system (PBSO NPs) using bovine serum albumin as a carrier, with polyallylamine hydrochloride surface modification to enhance α-Sol delivery.Methods: PBSO NPs were characterized using transmission electron microscopy, dynamic light scattering, nanoparticle size analyzers, and Fourier-transform infrared spectroscopy. …”
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8377
Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening
Published 2025-07-01“…Wenqiang Li,1,* Youli Wen,1,* Yuting Fan,2 Zefu Hu,3 Zhiping Deng,1 Qian Huang3 1Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan Province, 643000, People’s Republic of China; 2Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province, 637000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, Sichuan Province, 635000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Huang, Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, 635000, Sichuan Province, People’s Republic of China, Tel +8615196767955, Email hq15196767955@163.com Zhiping Deng, Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, 643000, Sichuan Province, People’s Republic of China, Tel +8613608158051, Email zgsdzp1016@163.comPurpose: This study aims to investigate the association between the Life’s Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.Patients and Methods: We screened the NHANES database for data from 2007– 2018. …”
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8378
Self-Esteem and College Students’ Online Impulse Buying: The Independent and Interactive Moderating Role of Interdependent Self-Construal and Interpersonal Relationships
Published 2024-12-01“…Drawing on the theory of compensatory consumption, the current study aimed to examine the influence of self-esteem on college students’ online impulse buying and the independent and interactive moderating role of interdependent self-construal and interpersonal relationships.Patients and Methods: This study recruited 323 college students through random sampling and invited them to complete self-reported questionnaires measuring self-esteem, online impulse buying, interdependent self-construal, and interpersonal relationships. …”
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8379
Health utility value of overactive bladder in Japanese older adults
Published 2025-01-01“…Abstract Objectives To determine the health utility values (HUVs) of overactive bladder (OAB), defined as urinary urgency, usually accompanied by urinary daytime or nocturnal frequency, with or without urinary incontinence, among adults aged ≥65 years and to assess the HUV decrements (disutilities) of OAB according to its severity. Methods This cross‐sectional Internet‐based study was conducted between 2 and 9 November 2023, with quota sampling with equal probability for each sex and age group (age 65–74 years and ≥75 years). …”
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8380
The Effects of Hyperlipidemia on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Gynecological Tumor Surgery
Published 2025-02-01“…However, the association between hyperlipidemia and POCD has not been well examined.Methods: A total of 98 patients were divided into hyperlipidemia group and normal lipid group based on blood lipid level. …”
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