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8321
Antibiofilm and Anticancer Activity of Multi-Walled Carbon Nanotubes Fabricated with Hot-Melt Extruded Astaxanthin-Mediated Synthesized Silver Nanoparticles
Published 2025-01-01“…The antibiofilm and anticancer effects were studied comprehensively by loading the AST AgNPs onto MWCNT-Silica.Methods: AgNPs-loaded MWCNT-silica (MWCNT-Ag) was prepared through the binding reaction of TSD and silanol groups and the aggregation interaction of Ag and TSD. …”
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8322
Ultrasound guided thoracic dorsal root ganglia pulsed radiofrequency verified by fluroscopy for patients with lung cancer and metastatic thoracic cage pain: a randomized controlled...
Published 2025-12-01“…The current study aimed to investigate the effect of ultrasound guided pulsed radiofrequency (PRF) of thoracic DRG on metastatic thoracic cage pain intensity and impact of pain on daily life of patients with lung cancer.Materials and Methods 30 patients with lung cancer thoracic cage metastatic pain were randomized equally to receive active PRF plus 0.5 ml lidocaine 2% for each thoracic DRG modulation (group 1) or non-active PRF plus 0.5 ml of lidocaine 2% (group 2). …”
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8323
Evaluation of comparative efficacy of Celastrus paniculatus (Jyotishmati) capsule versus sertraline capsule in the management of Chittodvega (generalized anxiety disorder): protoco...
Published 2024-10-01“…Aim and objectives To evaluate the comparative efficacy of Jyotishmati versus sertraline in the management of Chittodvega. Methods In this randomized active controlled double blind equivalence trial a total of 70 patients will be enrolled and divided into two equal groups. …”
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8324
EPIDEMIOLOGICAL ANALYSIS OF CARIES IN CHILDREN DURING OUT-PATIENT TREATMENT IN DONETSK REGION
Published 2018-03-01“…The purpose of this work is an epidemiological analysis of caries in children during out-patient treatment at the dentist`s in Donetsk region. Material and methods. The data of 33 697 children of three age groups were analyzed. …”
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8325
Unveiling Ventilator-Associated Pneumonia: S100A8 as a Promising Biomarker Through Integrated RNA-Seq Analysis
Published 2024-12-01“…There was an urgent need for new diagnostic biomarkers for VAP.Methods: The transcriptome of VAP patients was analyzed and computed using bioinformatics techniques in this study. …”
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8326
Plasma Fetuin-B Levels are Associated with Nervous Symptoms and Conduction Velocity in Patients with Painful DPN
Published 2025-03-01“…Ke Lin,1,* Xiaocui Wang,2,* Tao Gu,3,* Keduo Feng,1 Wang Zeng,1 Liu Yang1 1Department of Neurology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing, People’s Republic of China; 2Department of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, Second Affiliated Hospital of Army Medical University, Chongqing, People’s Republic of China; 3Department of Radiology, Second Affiliated Hospital of Army Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ke Lin; Liu Yang, Department of Neurology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing, People’s Republic of China, Email ayalinke@126.com; 510586640@qq.comAim: To assess the plasma concentrations of the novel hepatokine fetuin-B in individuals with type 2 diabetes with or without diabetic peripheral neuropathy (DPN), and to evaluate the relationship among fetuin-B levels, nervous function, and metabolic parameters.Methods: A total of 333 participants were recruited and divided into three groups: DPN, painful DPN (pDPN), and non-DPN. …”
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8327
Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation
Published 2025-08-01“…Yijing Zhou,* Chengli Lou,* Xiuqin Xu, Bo Feng, Xiaoping Fan, Xiangjing Wang Department of Nephropathy, Jiaxing Traditional Chinese Medicine Hospital, Jiaxing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yijing Zhou, Email zyj13967332522@163.comPurpose: Ursolic acid (UA) improves diabetic nephropathy (DN), but its regulatory mechanism requires further verification.Methods: The bioactive component-target network of UA in DN was determined using a network pharmacology approach. …”
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8328
Ultrasound-guided pulsed radiofrequency versus perineural platelet rich plasma injection for the treatment of idiopathic carpal tunnel syndrome: a prospective randomized controlled...
Published 2025-08-01“…The secondary outcomes included functional outcome evaluated by the Boston Carpal Tunnel Questionnaire (BCTQ), Nerve Conduction Velocity (NCV) and median nerve cross-sectional area (CSA). Methods This prospective, double-blinded, randomized controlled study was conducted on Seventy-five patients diagnosed with mild to moderate CTS, they were randomly allocated into three equal groups. …”
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8329
Real-World Pharmacovigilance Analysis of Adverse Events Associated with Liposomal Bupivacaine and Bupivacaine
Published 2025-04-01“…The primary goal of this study was to conduct a thorough safety evaluation of liposomal bupivacaine and bupivacaine.Patients and Methods: This study analyzed adverse events (AEs) associated with liposomal bupivacaine and bupivacaine using the FDA Adverse Event Reporting System (FAERS) database from Q1 2004 to Q2 2024. …”
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8330
Exploring Ototoxicity Associated with Capmatinib: Insights from a Real-World Data Analysis of the FDA Adverse Event Reporting System (FAERS) Database
Published 2025-06-01“…The aim of this study was to explore the significant adverse drug reactions (ADRs) associated with Capmatinib through the FDA Adverse Event Reporting System (FAERS) database.Methods: We employed the reported odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and the Empirical Bayes Geometric Mean (EBGM) as primary algorithms for the disproportionality analysis. …”
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8331
Development of a capability framework for Allied Health research careers in health services
Published 2025-02-01“…Pre-existing frameworks focus largely on research capabilities within the academic context, and do not adequately capture the specific capabilities required of AH research roles in health services. Equally, existing frameworks assume a career progression that moves from clinical practice, through a PhD and then onto a research academic path, and hence have limited relevance for other types of research roles that exist within health services. …”
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8332
Possibilities of a software-based hybrid single photon emission computed tomography/ magnetic resonance imaging in the diagnosis of complicated diabetic foot syndrome
Published 2016-03-01“…Objective: to give the results of a software-based hybrid single photon emission computed tomography/magnetic resonance imaging (SPECT/MRI) in detecting osteomyelitis (OM) in patients with diabetic foot syndrome (DFS).Material and methods. Seventy-six patients (35 men and 41 women) (mean age, 59.4±7.1 years) with type 1 and 2 diabetes mellitus and suspected OM were examined. …”
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8333
Six weeks of either EPA-rich or DHA-rich Omega-3 supplementation alters submaximal exercise physiology in endurance trained male amateurs
Published 2025-08-01“…The current study aimed to investigate if EPA-rich or DHA-rich supplements are equally efficient at modifying physiological responses to submaximal exercise and potentially improving performance.MethodsFifty-five endurance trained amateurs participated in a submaximal exercise test followed by a 24 km time trial (TT) before and after a six-week supplementation period. …”
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8334
An Evidence-Based Medical Review on Preoperative Exercise Prehabilitation in Lung Cancer Patients
Published 2025-08-01“…To integrate and evaluate the evidence related to preoperative exercise prehabilitation in patients with lung cancer.Methods: Conducted utilizing the “ 6S” model of evidence resources, according to the search strategy searching for relevant guidelines, evidence summaries, best practices, systematic reviews, and expert consensuses on preoperative exercise prehabilitation for lung cancer patients. …”
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8335
Predicting Time to First Rejection Episode in Lung Transplant Patients Using a Comprehensive Multi-Indicator Model
Published 2025-01-01“…This study aimed to develop and validate a prognostic model using laboratory data to predict the time to first rejection episode in lung transplant recipients.Methods: Data from 160 lung transplant recipients were retrospectively collected. …”
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8336
China’s position and competitiveness in the global antibiotic value chain: implications for global health
Published 2024-12-01“…This is important for discussions about equitable and resilient global supplies, including through global instruments such as the pandemic treaty. Methods This study utilizes data from the International Trade Center database to analyze global and Chinese export trade patterns in the antibiotic industry from 2002 to 2021, along with trends in comparative advantage. …”
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8337
New Drug Approvals in China: An International Comparative Analysis, 2019-2023
Published 2025-04-01“…This study aims to analyze and compare the trends in new drug approvals in China, the United States (US), the European Union (EU), and Japan from 2019 to 2023.Methods: Data on new drug approvals were collected from the National Medical Products Administration (NMPA), Food and Drug Administration (FDA), European Medicines Agency (EMA), and Pharmaceuticals and Medical Devices Agency (PMDA), including information on the generic name, trade name, applicants, target, approval date, drug type, approved indications, therapeutic area, the highest R&D status in China, and special approval status. …”
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8338
Assessing microvascular dysfunction and predicting long-term prognosis in patients with cardiac amyloidosis by cardiovascular magnetic resonance quantitative stress perfusion
Published 2025-01-01“…This study sought to investigate the extent of microvascular dysfunction and its incremental prognostic value in cardiac light-chain amyloidosis (AL-CA) by quantitative stress perfusion. Methods: A total of 126 AL amyloidosis patients (61.13 ± 8.46 years, 81 male) confirmed by pathology were prospectively recruited. …”
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8339
Evaluation of the Cost-Effectiveness of Vaccination of Children with 5-valent Vaccine against Rotavirus Infection in the Russian Federation
Published 2018-01-01“…Vaccines against rotavirus infection substantially reduce morbidity.The objective of this study is to analyze cost-effectiveness of vaccination of children with 5-valent vaccine against rotavirus infection in the Russian Federation.Methods. The evaluation was carried out using modelling on the basis of published data on the effectiveness of vaccines and epidemiological data for the Russian Federation. …”
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8340
Monetary Fines in EU Mergers: In Need for More Regulation
Published 2019-04-01“…The third section deals with Article 14(3) and the fining methods on mergers. By reviewing each of these five cases, it is important to address factors taken into consideration when imposing fines. …”
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