The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

“…Yintao Wu,* Jianyong Zhu,* Hong Zhang, Nianxin Xia Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nianxin Xia, Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China, Email doctorxnx@163.comPurpose: This study was developed to compare the efficacy of combined D-TACE-HAIC + lenvatinib + PD-1 inhibitor treatment to that of TACE + sorafenib treatment for patients with intermediate and advanced HCC.Patients and Methods: Here, a retrospective analysis of patients with unresectable HCC who underwent transarterial chemoembolization (TACE) from March 2018 to March 2022 at the our hospital was conducted. …”
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Health behavior and disease self-management indicators in patients with cardiovascular diseases using a health app: Findings from an RCT by Sonia Lippke, Luisa Korte, Vinayak Anand Kumar, Andreas Fach, Tiara Ratz

“…A total of N = 40 CVD patients were randomized equally to the CG (45% women; mean age = 60.6 years) and the IG (35% women; mean age = 61.5 years).ResultsFindings support H1 with correlations between behaviors (r = −0.66–0.79) and disease self-management (r = −0.06–0.70). …”
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Mortality trends from 2003 to 2009 among adolescents and young adults in rural Western Kenya using a health and demographic surveillance system. by Penelope A Phillips-Howard, Frank O Odhiambo, Mary Hamel, Kubaje Adazu, Marta Ackers, Anne M van Eijk, Vincent Orimba, Anja van't Hoog, Caryl Beynon, John Vulule, Mark A Bellis, Laurence Slutsker, Kevin deCock, Robert Breiman, Kayla F Laserson

“…<h4>Background</h4>Targeted global efforts to improve survival of young adults need information on mortality trends; contributions from health and demographic surveillance system (HDSS) are required.<h4>Methods and findings</h4>This study aimed to explore changing trends in deaths among adolescents (15-19 years) and young adults (20-24 years), using census and verbal autopsy data in rural western Kenya using a HDSS. …”
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Embryological considerations and evaluation of congenital anomalies of craniovertebral junction: A single-center experience by Reddy Ravikanth, Pooja Majumdar

“…The present study was undertaken to know the embryological basis of the CVJ and to identify commonly observed congenital CVJ abnormalities, their frequency, and mode of presentation. Materials and Methods: Diagnosed cases of CVJ anomalies on dynamic MDCT head were reviewed at a tertiary care center between January 2014 to December 2019. …”
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Impact of New-Onset Atrial Fibrillation on Mortality in Critically Ill Patients by Zhang HD, Ding L, Mi LJ, Zhang AK, Liu YD, Li XN, Yan XX, Shen YJ, Tang M

“…This study sought to evaluate the impact of new-onset AF on mortality in a critically ill population.Methods: This study identified 48018 adult patients admitted to the ICU from the Medical Information Mart for Intensive Care (MIMIC)-IV database. …”
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Comparative Assessment of the Dynamics of Visual Performance of a Patient with Visually Intense Work with Binocular Cataract after Various Technologies of Cataract Phacoemulsificat... by D. F. Pokrovsky, I. B. Medvedev, N. I. Ovechkin, I. G. Ovechkin, A. I. Pavlov

“…Comparative assessment of the dynamics of visual performance (VP) of a patient with visually intense work with binocular cataract after various technologies of cataract phacoemulsification (PEC).Methods. There were 300 patients with binocular cataract under our observation. …”
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A Risk Model Based on sCD25 for Early Mortality in Adult Patients with Hemophagocytic Lymphohistiocytosis by Li C, Lv K, Zhou Y, Cheng X, Li F

“…We aim to investigate the characteristics of the early death (ED) in adults with HLH and develop a reliable risk model to predict early mortality.Materials and Methods: Between September 2013 and July 2024, 254 adult patients with HLH were examined. …”
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Preferences for home-based care services during China’s long-term care market transition: evidence from a discrete choice experiment by Zihan Ni, Xiuyuan Zhu, Jing Guo, Shiyu Xie, Shimeng Liu, Xiaoguang Yang

“…Results For respondents, the service attitude of nursing staff (relative importance 29.59%), and the nursing program (29.30%) are of almost equal importance, followed by the monthly cost (20.62%). …”
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Multiomics-Based Deep Learning Prediction of Prognosis and Therapeutic Response in Patients With Extensive-Stage Small Cell Lung Cancer Receiving Chemoimmunotherapy: A Retrospectiv... by Nie F, Pei X, Du J, Shi W, Wang J, Feng L, Liu Y

“…Fang Nie,&ast; Xiufeng Pei,&ast; Jiale Du, Wanting Shi, Jianying Wang, Lu Feng, Yonggang Liu Department of Thoracic Oncology, Baotou Cancer Hospital, Baotou, Inner Mongolia, 014000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yonggang Liu, Email zlnkldf8000@sina.comObjective: This study aimed to develop a clinical early warning prediction model to evaluate the prognosis and response to chemoimmunotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC), thereby guiding clinical decision-making.Methods: A retrospective analysis was conducted on the clinical data and radiomics parameters of 309 patients with ES-SCLC hospitalized at Baotou Cancer Hospital from February 2020 to September 2024. …”
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EFFICACY AND SAFETY OF A NEW COMBINED MEDICATION WITH RECOMBINANT INTERFERON AND BETAMETHASONE IN THE TREATMENT OF HAY FEVER DURING PERIODS OF EXACERBATION by A. A. Ryabtseva, N. Y. Sotnikova, O. V. Chumikov, N. A. Stupakova

“…Patients were divided into two equal groups. The main group received Allergoferon® beta, the control group was treated with Oftan® Dexamethasone and Nasobek medications. …”
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TWELVE-WEEK MULTICENTER OPEN-LABEL RANDOMIZED COMPARATIVE STUDY OF THE EFFICACY AND SAFETY OF METHOTREXATE AS A CONCENTRATED SOLUTION FOR SUBCUTANEOUS ADMINISTRATION AND AS 15-MG T... by Yu. V. Muravyev, V. I. Mazurov, E. L. Nasonov

“…Objective: to evaluate of the efficacy of methotrexate (MTX) as a concentrated solution (50 mg/ml) for subcutaneous administration versus coated tablets at equal oral doses of 15 mg/week for rheumatoid arthritis (RA).Subjects and methods. …”
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Mean perfusion pressure in cardiopulmonary bypass as a factor of intraoperative acute kidney injury by D. V. Sokolov, R. V. Akmalova, N. S. Molchan, I. V. Bovkun, O. V. Galkina, Yu. S. Polushin

“…The OBJECTIVE was to evaluate the role of mean perfusion pressure in the development of acute kidney injury (AKI) in patients operated with CPB.METHODS AND MATERIALS. A retrospective monocenter observational study was conducted among patients CPB (n=97) who underwent planned heart surgery using CPB. …”
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Comparative Study and Transcriptomic Analysis on the Antifungal Mechanism of Ag Nanoparticles and Nanowires Against Trichosporon asahii by Han M, Xia Z, Zou Y, Hu P, Zhang M, Yang X, Ma MG, Yang R

“…However, the antifungal mechanism of silver nanomaterials with different morphologies still needs to be explored.Methods: Herein, the antifungal effect of silver nanomaterials against fungus was comparative investigated via silver nanowires and silver nanoparticles with a similar size (30 nm).Results: The optimal antifungal concentration of silver nanowires is 6.24 μg/mL, meanwhile the antifungal concentration of silver nanoparticles is 100 μg/mL. …”
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Graphene Oxide Nanosheets Induce Mitochondrial Toxicity in Human Ovarian Granulosa Cells: Implications for Female Reproductive Health by Li M, Lu H, Ye C, Wang X, Ji D, Zhang Z, Cao Y, Zou W

“…This study investigates the short-term effects of a single dose of GO nanosheets on human ovarian granulosa cells, focusing on mitochondrial damage.Materials and Methods: First, cell viability was detected by CCK-8 and apoptosis was detected by flow cytometry to assess the cytotoxicity of GO on KGN. …”
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A Psychometric Analysis of the Polish Online Version of the Aging Semantic Differential Scale (ASD) by Puto G, Wadelska-Kaczmarek A, Muszalik M

“…The aim of the study was to analyse the psychometrics of the Polish online version of the Aging Semantic Differential Scale (ASD).Methods: The study was conducted among 384 students of bachelor’s and master’s degree studies in nursing (94.3%) and other medical disciplines: midwifery and emergency medical services (5.7%). …”
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Diagnostic Performance of Infrared Thermography, Quantitative Sudomotor Axonal Reflex Testing, and 3-Phase Bone Scintigraphy for Complex Regional Pain Syndrome Diagnosis: A Retrosp... by Noh C, Lee J, Choi HY, Park E, Shin YS, Hong B, Ko Y, Oh C, Lee SY

“…This retrospective study aimed to elucidate the diagnostic validity and potential value of these modalities for the diagnosis of CRPS.Patients and Methods: The Budapest criteria were used to diagnose CRPS, and infrared thermography, QSART, and 3-phase bone scintigraphy were performed as ancillary tests. …”
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Ultrasonic Bone Scalpel in Anterior Cervical Discectomy and Fusion Enhances Outcomes and Foraminal Decompression in Cervical Radiculopathy: A Retrospective Cohort Study by Peng Z, Xiong Y, Jia Y, Li J, Liu Z, Wang G

“…No significant differences in complication rates, including dural tears or nerve root injuries, were found between the two groups.Conclusion: The ultrasonic bone scalpel-assisted decompression technique offers significant advantages over traditional methods in terms of surgical outcomes, including better pain relief, functional recovery, and foraminal enlargement, while maintaining comparable safety profiles.Keywords: ultrasonic bone scalpel, anterior cervical discectomy and fusion, ACDF, foraminotomy, smallest oblique sagittal area…”
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Effect and Safety of Finerenone in Patients with IgA Nephropathy by Guo Y, Zhang X, Zhao S, Wang Y, Wang L, Li Q, Yu L, Tang L

“…Yanhong Guo,&amp;ast; Xuewen Zhang,&amp;ast; Silu Zhao,&amp;ast; Yulin Wang, Liuwei Wang, Qiuhong Li, Lu Yu, Lin Tang Department of Nephropathy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Lin Tang, Department of Nephropathy, the First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou, Henan, 450052, People’s Republic of China, Tel +8613838194409, Email tanglin@zzu.edu.cnPurpose: The study aimed to retrospectively evaluate the efficacy and safety of finerenone in patients diagnosed with IgA nephropathy.Methods: 42 IgA nephropathy patients treated with finerenone combined with renin–angiotensin system inhibitor (RASI) and 42 patients who received RASI monotherapy were included in this study. …”
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Childhood Maltreatment and Internet Addiction: A Moderated Mediation Model of Depression and Physical Activities by Li S, Zhang L, Song L, Fan T, Li Y, Shen Y

“…This study investigates the mediating role of depression and the moderating role of physical activity in the relationship between childhood maltreatment and adolescent internet addiction.Methods: Data from 1610 Chinese middle school students were analyzed using statistical software: Mplus 8.3 was used for SEM, while SPSS 26.0 and Hayes’ PROCESS Macro were used for correlation analyses, hierarchical regression, and moderated mediation model.Results: Results showed that emotional abuse was significantly positively associated with internet addiction and the association was mediated by depression. …”
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Is Race Associated with Referral Disparities for Patients with Diabetic Foot Ulcers? by Kyle M. Schweser MD, Mubinah Khaleel DO, Ashwin Garlapaty, Sam Hawkins, James Cook DVM, PhD, Kylee Rucinski PhD, MHA

“…This retrospective study was designed to determine 1) the associations of race and living status with rates of referral to specialists for DFU treatment, and 2) the severity of DFU at time of initial presentation. Methods: Patients were identified from the medical record based on a diagnosis related to diabetic foot ulcers made between January 01, 2018, and June 01, 2023, in the family medicine clinic, endocrinology clinic, or emergency department at a Midwest Level 1 Academic Hospital. …”
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