Restoration of sperm quality in lead acetate-induced rats via treatment with Moringa oleifera leaf extract by Wurlina Wurlina, Imam Mustofa, Dewa Ketut Meles, Aswin Rafif Khairullah, Adeyinka Oye Akintunde, Kadek Rachmawati, Niluh Suwasanti, Dewa Made Sucipta Putra, Sri Mulyati, Suzanita Utama, Ulul Khoiriyah, Baich R. Tyarraushananda Defvyanto, Sila Faredy Heriana, Katty Hendriana Priscilia Riwu, Riza Zainuddin Ahmad, Audrey Gracelia Riwu

“…Aim: This study aimed to explore the antioxidant potential of Moringa oleifera leaf extract (MOLE) in enhancing the semen quality of rats exposed to lead acetate. Methods: Twenty-five healthy rats were randomly and equally divided into five groups. …”
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Effect of cognitive-behavioral therapy combined with exercise training in adolescent girls with elevated depression symptoms: a randomized controlled clinical trial by Sally Mohamed Saeed Mahmoud, Doaa Tammam Atia, Doaa Sayed Mostafa, Mohamed Farouk Abdel-Latif, Lamyaa Ahmed Fergany, Neveen M. Abdulrahman, Kamal Eldin S. Mohamed, Malak A. Elmahdy

“… Objective: To investigate the effects of cognitive-behavioral therapy (CBT) combined with regular versus intermittent exercise on depression and quality of sleep-in adolescent girls. Participants and Methods: Sixty adolescent girls aged 12-17 years with mild to moderate depression were equally distributed to three groups, each group 20 patients. …”
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Prevalence of airway hyperresponsiveness and its seasonal variation in children with asthma by Shu-Jung Huang, Li-Lun Lin, Li-Chen Chen, Liang-Shiou Ou, Tsung-Chieh Yao, Kuo-Chien Tsao, Kuo-Wei Yeh, Jing-Long Huang

“…However, these studies have mostly been conducted in temperate regions.This study evaluated the prevalence of AHR to methacholine and its seasonal variation in asthmatic children in Taiwan, a subtropical country. Methods: A total of 276 children with asthma and their MCCT results were retrospectively reviewed. …”
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Proteomics analysis reveals the mechanism of anemoside B4 in treating clinical mastitis in dairy cows by Zeru Zhang, Yuquan Zhao, Zhetong Su, Ke Dong, Zhicai Zuo, Yixin Huang, Shumin Yu, Suizhong Cao, Liuhong Shen

“…This study was based on Label free relative quantitative proteomics technology to reveal the internal mechanism of AB4 treatment of CM; (2) Methods: Twelve healthy Chinese Holstein cows (group C) and twelve Chinese Holstein cows (group T) with CM were selected. …”
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Evaluating the Reliability of Anatomic Landmarks in Safe Lumbar Puncture Using Magnetic Resonance Imaging: Does Sex Matter? by Maryam Rahmani, Seyed Mehran Vaziri Bozorg, Ahmad Reza Ghasemi Esfe, Afsaneh Morteza, Omid Khalilzadeh, Elham Pedarzadeh, Madjid Shakiba

“…To determine the level of the conus medullaris-Tuffier's line, and conus medullaris-Tuffier's line distance using imaging and evaluate their relation to age and gender. Methods. We performed a cross-sectional study of 189 adult participants, who underwent MR imaging of lumbosacral spine. …”
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Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles by O. A. Puchenkova, O. V. Shheblykina, D. A. Kostina, A. A. Bolgov, P. R. Lebedev, V. V. Molchanov, T. G. Pokrovskaya, M. V. Korokin, E. A. Nikiforov, N. F. Vaskina, T. A. Idrisov, T. D. Moseev, V. V. Melekhin, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin

“…To study the acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles.Materials and methods. The study was performed on white laboratory female BALB/c mice (n=57) and male C57Bl/6 mice (n=66). …”
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Clinical and epidemiological characteristics of imported intestinal infections in children by E. Yu. Pylaeva, N. N. Zverevа, А. А. Erovichenkov, S. K. Pylaeva, E. A. Artamonova, N. Yu. Pshenichnaya, A. M. Demkina, O. N. Solodovnikova, Yu. N. Khlypovka, A. Yu. Dyagileva, A. Kh. Nurpeysova, A. U. Berestovskaia, O. V. Shamsheva, D. N. Protsenko

“…In the case of traveling abroad, the prevailing purpose was tourism, with equal proportions staying in a hotel or private sector. …”
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Acute safety, cardiovascular, perceptual and neuromuscular responses to autoregulated and non-autoregulated blood flow restriction training during elbow rehabilitation in people wi... by Daniel C. Ogrezeanu, Andrea Tur-Boned, Nicholas Rolnick, Nicholas Rolnick, Juan J. Carrasco, Juan J. Carrasco, Carlos Cruz-Montecinos, Carlos Cruz-Montecinos, Joaquín Calatayud, Santiago Bonanad, Sofía Pérez-Alenda

“…Therefore, this study aimed to evaluate the acute safety, cardiovascular, neuromuscular and perceptual responses during AUTO and NAUTO BFR training in PWH.MethodsEleven severe PWH under prophylaxis performed two sessions of elbow flexion and extension using elastic bands at 50% of the limb occlusion pressure (LOP) with different BFR settings (AUTO vs. …”
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Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases by Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, Cristian Papara, David A. De Luca, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, Matthias Laudes, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Ralf J. Ludwig, Ralf J. Ludwig

“…Yet, several knowledge gaps remain: For several CIDs, inconsistent results have been reported, relating to their obesity-imposed risk, data on most rare CIDs remain unavailable, sex differences and racial disparities remain mostly unaddressed.MethodsA large-scale cohort study compared the risk of developing 46 CIDs in individuals with overweight/obesity (n=3,101,824) to an equal number of non-overweight/obese individuals. …”
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Long-term effect of treatment for non-muscle invasive bladder cancer on Quality of life: a cross-sectional study by Rikke Vilsbøll Milling, Ninna Kjær Nielsen, Charlotte Graugaard-Jensen, Peter Christensen, Helle Pappot, Jørgen Bjerggaard Jensen

“…Both cases and controls scored equally on the functional items and symptom items of the EORTC-QLQ-C30. …”
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Humanising processes after harm part 2: compounded harm experienced by patients and their families after safety incidents by Lauren Ramsey, Joanne Hughes, Debra Hazeldine, Sarah Seddon, Mary Gould, Jo Wailling, Jenni Murray, Siobhan McHugh, Ruth Simms-Ellis, Ruth Simms-Ellis, Daisy Halligan, Katherine Ludwin, Jane K. O’Hara

“…However, the latter, termed ‘compounded harm’ is rarely acknowledged.AimsWe aimed to explore the ways compounded harm is experienced by patients and their families as a result of organisational responses to safety incidents and propose how this may be reduced in practice.MethodsWe used framework analysis to qualitatively explore data derived from interviews with 42 people with lived or professional experience of safety incident responses. …”
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Risk Warning of Neutrophil‐to‐Lymphocyte Ratio for Neurological Recovery in Acute Ischemic Stroke After Thrombolysis: A Retrospective Study by Yiran Zhao, Xu Wang, Wenxiu Qin, Shaojing Shi, Min Wang, Jinsheng Zhang, Xin Zou, Junfeng Xu, Jing Li, Xuemin Shi

“…ABSTRACT Background To investigate the relationship between dynamic changes in the neutrophil‐to‐lymphocyte ratio (NLR) and neurological recovery in noninfected patients with acute cerebral infarction after thrombolysis. Methods A retrospective analysis was conducted on 277 patients with stroke thrombolysis. …”
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Comparative analysis of upper body postural angles and their association with neck pain in car and motorcycle drivers by Aafreen Aafreen, Abdur Raheem Khan, Ashfaque Khan, Ausaf Ahmad, Monira I. Aldhahi, Weam Okab Alsalem, Mohammed M Alshehri, Almutasim Billa Moafa, Ahmed Ghazwani, Mohammad Abu Shaphe

“…Purpose: This study aimed to assess upper-body postural angles and neck pain among car drivers and motorcycle drivers separately, and to compare these outcomes between the two groups. Methods: This cross-sectional study comprised a total of 200 participants, with an equal distribution between car drivers (n = 100) and motorcycle drivers (n = 100). …”
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Global inequalities in arts, music or educational organization membership: an epidemiological analysis of 73,825 adults from 51 countries by Hei Wan Mak, Jessica K. Bone, Taiji Noguchi, Joeun Kim, Rina So, Emma Walker, Calum Smith, Marlee Bower, Ferdi Botha, Nisha Sajnani, Nils Fietje, Daisy Fancourt

“…Methods This study analyzed cross-sectional data from Wave 7 of the World Values Survey (2017–2023), with 73,825 respondents from 51 countries. …”
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Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis by Elizabeth Gorman, Hongzheng Dai, Hongzheng Dai, Yanming Feng, William James Craigen, William James Craigen, David C. Y. Chen, Fan Xia, Fan Xia, Linyan Meng, Linyan Meng, Pengfei Liu, Pengfei Liu, Robert Rigobello, Arpita Neogi, Christine M. Eng, Christine M. Eng, Yue Wang, Yue Wang

“…To assess the clinical utility of this approach, we describe the results from a retrospective review of patients having dual genome panel testing for mitochondrial disease.MethodsDual genome panel testing by NGS was performed on a cohort of 1,509 unrelated affected individuals with suspected mitochondrial disorders. …”
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Novel allelic variants of blaOXA-48-like carried on IncN2 and IncC2 plasmids isolated from clinical cases in Argentina: In vivo emergence of blaOXA-567 by Juan Manuel de Mendieta, Denise De Belder, Nathalie Tijet, Barbara Ghiglione, Roberto G. Melano, Melina Rapoport, Pablo Power, Adriana Di Bella, Estefanía Biondi, Fernando Pasterán, Alejandra Corso, Sonia A. Gomez

“…The aim of this study was to analyse the phenotypic profile and dissemination strategies of two novel OXA enzymes, blaOXA-438 and blaOXA-567, located in Escherichia coli M17224 and Klebsiella pneumoniae M21014, respectively, isolated from two paediatric patients. Methods: Minimum inhibitory concentration measurements were performed to determine the phenotypic profile of the clinical isolates, transconjugants and transformant cells. …”
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Development and the need for implementation of a health-related quality of life measurement strategy for patients with soft tissue sarcoma undergoing preoperative radiotherapy by Geraldien Florine Foppele, Lisette M. Wiltink, Marta Fiocco, Jules Lansu, Astrid N. Scholten, Winan J. van Houdt, Yvonne Schrage, Winette T.A. van der Graaf, Rick L.M. Haas, Olga Husson

“…Patients and methods: To address this gap, a sarcoma-specific tool was developed complementing the most used cancer-generic EORTC QLQ-C30 questionnaire, with additional items tailored to the specific challenges of radiotherapy and surgery in sarcoma patients. …”
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Non-Invasive Ventilation Failure in Pediatric ICU: A Machine Learning Driven Prediction by Maria Vittoria Chiaruttini, Giulia Lorenzoni, Marco Daverio, Luca Marchetto, Francesca Izzo, Giovanna Chidini, Enzo Picconi, Claudio Nettuno, Elisa Zanonato, Raffaella Sagredini, Emanuele Rossetti, Maria Cristina Mondardini, Corrado Cecchetti, Pasquale Vitale, Nicola Alaimo, Denise Colosimo, Francesco Sacco, Giulia Genoni, Daniela Perrotta, Camilla Micalizzi, Silvia Moggia, Giosuè Chisari, Immacolata Rulli, Andrea Wolfler, Angela Amigoni, Dario Gregori

“…This study aims to identify predictors of first-attempt NIV failure in PICU patients by testing various machine learning techniques and comparing their predictive abilities. <b>Methods</b>: Data were sourced from the TIPNet registry, which comprised patients admitted to 23 Italian Paediatric Intensive Care Units (PICUs). …”
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Evaluation of GFAP/UCH-L1 biomarkers for computed tomography exclusion in mild traumatic brain injury (mTBI) by Jacopo M. Legramante, Marilena Minieri, Marzia Belli, Alfredo Giovannelli, Alessia Agnoli, Daniela Bajo, Lorenza Bellincampi, Anna Maria De Angelis, Alessandro Terrinoni, Massimo Pieri, Eleonora Nicolai, Vito N. Di Lecce, Carla Paganelli, Gianluigi Ferrazza, Susanna Longo, Marco Ciotti, Sergio Bernardini

“…Combined biomarkers had a sensitivity equal to 1.00 (95% CI 0.64-1.00) and a negative predictive value (NPV) of 1.00 (0.99-1.00) in mTBI diagnosis with a negative CT. …”
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Radiomics Results for Adrenal Mass Characterization Are Stable and Reproducible Under Different Software by Giacomo Feliciani, Francesca Mascolo, Alberto Cossu, Luca Urso, Francesco Feletti, Enrico Menghi, Anna Sarnelli, Maria Rosaria Ambrosio, Melchiore Giganti, Aldo Carnevale

“…<i>Background</i>: This study aims to investigate stability and reproducibility of radiomics biomarkers for adrenal lesion characterization across different software packages. <i>Methods</i>: Unenhanced CT images from patients with adrenal tumors were analyzed. …”
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