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7941
Factor Analysis of the Effect of Hepatitis B-Related Liver Cancer Treatment Efficacy
Published 2025-06-01“…This study analyzes the clinical factors related to the overall survival (OS) and progression-free survival (PFS) of patients with hepatitis B-related hepatocellular carcinoma (HCC) treated with DEB-TACE to provide reference data for individualized treatment.Methods: In this retrospective study, 128 patients with hepatitis B-related primary liver cancer who received DEB-TACE treatment and being followed up (range of follow-up: 4– 39 months) were included. …”
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7942
Effect of two different digital construction techniques of mandibular implant-assisted overdentures on peri-implant bone loss and posterior ridge resorption: a 3-year prospective r...
Published 2025-07-01“…So, this study aimed to investigate the effect of two different digital construction techniques of implant-assisted overdentures on peri-implant and posterior mandibular bone resorptions by CBCT. Materials and methods Twenty patients who received mandibular overdenture constructed by different construction techniques were classified equally and randomly into two groups (n = 10 per group): Group M: received milled mandibular overdenture opposed by maxillary complete denture. …”
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7943
Network Pharmacology and Experimental Validation of the Effects of Shenling Baizhu San, Quzhi Ruangan Fang and Gexia Zhuyu Tang on the Intestinal Flora of Rats with NAFLD
Published 2025-04-01“…Jia Guo,1,2,* Anhua Shi,1,3,4,* Yanhong Sun,1 Shunzhen Zhang,1 Xiaoyi Feng,1,3,4 Yifan Chen,1 Zheng Yao1,3,4 1School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China; 2Dongtai Hospital of Traditional Chinese Medicine, Dongtai, Jiangsu, 224200, People’s Republic of China; 3The Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China; 4Yunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Yao, School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China, Tel +8618908719365, Email YaoYNUCM@163.comObjective: In this study, we investigated the effect of Shenling Baizhu San(SLBZS), Quzhi Ruangan Fang(QZRGF) and Gexia Zhuyu Tang(GXZYT) on the intestinal flora of NAFLD rats through network pharmacology and experimental validation.Materials and Methods: Protein-protein interaction, Gene Ontology (GO), and molecular docking were performed. …”
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7944
EVALUATION OF PERIODONTAL TISSUES CONDITION IN CHILDREN WITH BLOOD COAGULABILITY PATHOLOGY
Published 2014-02-01“…Hygiene index value was determined according to Fedorov and Volodkina, PMA index (papillary-marginal-alveolar index) was determined by standard methods. Visual presence of inflammation clinical signs and periodontal tissue condition was determined in each group. …”
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7945
A Retrospective Machine Learning Analysis to Predict 3-Month Nonunion of Unstable Distal Clavicle Fracture Patients Treated with Open Reduction and Internal Fixation
Published 2025-05-01“…Changke Ma,1,* Wei Lu,2,3,* Limei Liang,4,* Kaizong Huang,3 Jianjun Zou3,5 1Department of Orthopaedics, Nanjing Luhe People’s Hospital, Yangzhou University, Nanjing, People’s Republic of China; 2School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China; 3Department of Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 4Department of Rehabilitation, Nanjing Luhe People’s Hospital, Yangzhou University, Nanjing, People’s Republic of China; 5Department of Pharmacy, Nanjing First Hospital, China Pharmaceutical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kaizong Huang, Email kzhuang@nju.edu.cn Jianjun Zou, Email zoujianjun100@126.comBackground: This retrospective study aims to predict the risk of 3-month nonunion in patients with unstable distal clavicle fractures (UDCFs) treated with open reduction and internal fixation (ORIF) using machine learning (ML) methods. …”
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7946
Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization
Published 2025-01-01“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
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7947
Awareness, Knowledge, Attitude, and Source of Information on HIV Infection Among College Students
Published 2025-07-01“…Caixia Zheng,1,* Qingyun Tang,2,* Jianyong Zeng,1 Huiqun Zhong,2 Hongyan Xie,3 Hongjie Ou1 1Department of Infectious Diseases, First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, People’s Republic of China; 2Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 3Department of General Practice, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongjie Ou, Department of Infectious diseases, The First Affiliated Hospital of Xiamen University, No. 10, Shanggu Road, Siming District, Xiamen City, 361003, Fujian Province, People’s Republic of China, Email ouhongjie@sina.com Hongyan Xie, Department of General Practice, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou City, 510515, Guangdong Province, People’s Republic of China, Email 492577598@qq.comObjective: To evaluate the college students’ awareness, knowledge, attitude, and source of information on human immunodeficiency virus (HIV).Methods: This is a multicenter study with 490 college students participated in the questionnaire survey. …”
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7948
New compounds with a dihydropyridine framework as promising hypolipidemic and hepatoprotective agents
Published 2024-09-01“…The experimental results were statistically processed using the recognized methods of mathematical statistics. When processing the experimental data, the average arithmetic (AA) was determined. …”
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7949
Breast Cancer Knowledge and Attitude Toward Breast Cancer Screening Practice Among Catholic Nuns in Lake Zone—Tanzania
Published 2024-11-01“…Study design: The study was a cross-sectional design. Methods: A total of 385 Catholic nuns participated in the study. …”
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7950
Serum RIPK1, Acute Lung Injury, and Outcomes in Severe Traumatic Brain Injury: A Multicenter Prospective Study
Published 2025-03-01“…Multifactorial analytical methods were applied to assess relevancies.Results: Patients, as opposed to controls, had markedly raised serum RIPK1 levels, with the even substantially higher levels in those with lower GCS scores, bilateral pupil enlargement or obliterated basal cisterns. …”
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7951
Impact on Participation and Autonomy Questionnaire (IPA): Reliability and Validity of the Chinese Version for Stroke Survivors
Published 2025-03-01“…Ya-Nan He,* Xiao-Huan Qin,* Jian-Hong Lv, Yan-Ping Guo Department of Nursing, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Hong Lv; Yan-ping Guo, Department of Nursing, Shanghai East Hospital, School of Medicine, Tongji University, No. 150 Jimo Road, Pudong New Area, Shanghai, 200120, People’s Republic of China, Tel +86-18930805118 ; +86-13764211995, Email lv2253jh6@outlook.com; gyp13764211995@126.comPurpose: This study aimed to evaluate reliability and validity of the Chinese version of the Impact on Participation and Autonomy Questionnaire (IPA-C) for people with stroke.Methods: The English version of the IPA (IPA-E) was translated into the Chinese version using the protocol for linguistic validation of patient-reported outcome instruments. …”
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7952
Comprehensive Analysis of the Role of Heat Shock Proteins in the Immune Microenvironment and Clinical Significance of Hepatocellular Carcinoma
Published 2025-02-01“…However, the specific role of HSPs in HCC requires further investigation.Methods: We analyzed the genomic characteristics of HSPs in liver cancer in the TCGA and ICGC databases, and functional enriched analysis of HSPs. …”
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7953
Predicting Resistance and Survival of HCC Patients Post-HAIC: Based on Shapley Additive exPlanations and Machine Learning
Published 2025-05-01“…Fan Yao,1,2,* Jianliang Miao,3,* Bing Quan,1,2 Jinghuan Li,1,2 Bei Tang,1,2 Shenxin Lu,1,2 Xin Yin1,2 1Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2National Clinical Research Center for Interventional Medicine, Shanghai, People’s Republic of China; 3First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Yin, Liver Cancer Institute, Zhongshan Hospital, Fudan University, 136 Yi Xue Yuan Road, Shanghai, People’s Republic of China, Email yin.xin@zs-hospital.sh.cnPurpose: To establish prediction models using Shapley Additive exPlanations (SHAP) and multiple machine learning (ML) algorithms to identify clinical features influencing hepatic arterial infusion chemotherapy (HAIC) resistance and survival in patients with hepatocellular carcinoma (HCC).Patients and Methods: We recruited 286 patients with unresectable HCC who underwent HAIC. …”
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7954
Can Peritumoral Radiomics Based on MRI Predict the Microvascular Invasion Status of Combined Hepatocellular Carcinoma and Cholangiocarcinoma Before Surgery?
Published 2025-07-01“…Le Guo,1,2,* Chantao Huang,2,* Peng Hao,2,* Ningyang Jia,3 Ling Zhang2,4 1Lab of Molecular Imaging and Medical Intelligence, Department of Radiology, Longgang Central Hospital of Shenzhen (Shenzhen Clinical Medical College, Guangzhou University of Chinese Medicine), Shenzhen, 518116, People’s Republic of China; 2Department of Imaging Diagnosis, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s Republic of China; 3Department of Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, People’s Republic of China; 4Medical Imaging Department of Ganzhou People’s Hospital, Ganzhou, 341000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ling Zhang, Department of Imaging Diagnosis, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s Republic of China, Tel +86-2062786561, Email zhangling_smu@163.com Ningyang Jia, Department of Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, People’s Republic of China, Tel +86-02181875211, Email jianingyang6@163.comObjective: To investigate the role of MRI peritumoral imaging in predicting microvascular invasion (MVI) status in patients with combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CCA).Methods: Clinical and pathological data and MRI images of 118 patients with surgically resected and pathologically confirmed cHCC-CCA were retrospectively collected. …”
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7955
A Comprehensive Bibliometric Analysis of Brucellosis Research: Insights from CNKI and Web of Science Databases (2014-2023)
Published 2025-05-01“…Jin Wang,1,2,* Qing Cao,3,* Shijun Guo,1,2 Yonglin Li,1,2 Guowei Li,1,2 Chunjiang Yan,1,2 Minan Zheng,1,2 Dawei Wang,4 Xiaotu Xi1,2 1Emergency Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine(Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, People’s Republic of China; 2The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China; 3The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 4The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dawei Wang, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China, Tel +8613580469953, Email david@gzucm.edu.cn Xiaotu Xi, Emergency Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine(Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, People’s Republic of China, Tel +8613929556092, Fax +86-020-81887233, Email xxttm@gzucm.edu.cnPurpose: This study aimed to analyze the current status, research hotspots, and frontiers of brucellosis from 2014 to 2023 using data from China National Knowledge Infrastructure (CNKI) and Web of Science (WoS) via CiteSpace, and to provide new insights for researchers in the field.Material and Methods: Articles related to brucellosis published from 2014 to 2023 were retrieved from CNKI and WoS databases. …”
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7956
Determining the optimum high-flow nasal cannula flow rate to achieve the desired fraction of inspired oxygen: A bench study
Published 2025-08-01“…Therefore, we introduced a new variable, defined as flow ratio, which equaled the HFNC flow divided by inspiratory flow. …”
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7957
Sleep quality, daytime sleepiness, and obstructive sleep apnea risk among iranian commercial airline pilots
Published 2025-12-01“…In this matched cross-sectional comparative study, the sleep status and related factors in commercial airline flight pilots were evaluated. Methods: All pilots and the healthy sex- and age-matched controls who met the inclusion criteria and signed informed consent were included in the study. …”
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7958
Retrospective Evaluation of Synovial Chondromatosis with Histopathological and Clinical Features
Published 2025-08-01“…Results: A total of 114 cases were identified, with a nearly equal gender distribution (male-to-female ratio: 0.95). …”
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7959
The effect of preventive administration of metaraminol on hypothermia and shivering in cesarean section patients randomized clinical trial --a randomized controlled study
Published 2025-07-01“…This study aims to evaluate whether prophylactic low-dose metaraminol infusion, compared to saline control, reduces intraoperative hypothermia and shivering in cesarean section patients under spinal anesthesia.MethodsThis study is a randomized, double-blind, placebo-controlled trial, including a total of 66 full-term pregnant women scheduled for cesarean section under spinal anesthesia. …”
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7960
Allelopathic activity of Phragmites australis against Bolboschoenus planiculmis and the involved active allelochemicals
Published 2025-06-01“…(reed) in natural wetland communities; however, the allelopathic activity of reed on B. planiculmis remains poorly understood.MethodsThis study investigated the allelopathic effects of reed on B. planiculmis and identified the phenolic allelochemicals involved. …”
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