Cluster Set Resistance Training Reduces Autonomic Perturbations Compared to Traditional Protocols in Trained Healthy Young Individuals: A Clinical Study by Bianca de Souza Soares, Maria Clara Gomes Alves, Carlos Eduardo Cantelmo, Bruna Cristina de Oliveira Barros, Gustavo Vieira de Oliveira

“…Objectives: This study investigates the effects of cluster set resistance training (RT) on heart rate variability (HRV) parameters in young, healthy individuals. Methods: This trial was registered in the Brazilian Clinical Trials Registry (ReBEC) under the identification number RBR-9857xj3 on 7 December 2024. …”
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Study on the Mechanism of Artesunate in Modulating AR Epithelial Injury and Th2-Type Inflammatory Status by Bao Y, Zhang Z, Shi B, Chen Q, Zhang Y, Zhu X

“…Youwei Bao,* Zhiqiang Zhang,* Binbin Shi, Qi Chen, Ying Zhang, Xinhua Zhu Department of Otorhinolaryngology Head and Neck Surgery, The second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xinhua Zhu, Department of Otorhinolaryngology Head and Neck Surgery, The second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China, Email entzxh@126.comObjective: To evaluate the therapeutic efficacy of Artesunate (ART) in a mouse model of allergic rhinitis (AR) induced by house dust mite (HDM) and explore its underlying mechanism.Experimental Methods: Transcriptome sequencing (RNA-seq) analysis identified differentially expressed genes (DEGs) in nasal mucosa between healthy and allergic mice, with Gene Set Enrichment Analysis (GSEA) revealing STING pathway activation. …”
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Transparent memory tests with even repeating addresses for storage devices by V. N. Yarmolik, I. M. Mrozek, V. A. Levantsevich, D. V. Demenkovets

“…Mathematical models describing the faulty states of storage devices and the methods used for their detection are investigated. …”
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Association Between Hysterectomy and Accelerated Aging: Protective Effect of Dietary Fiber and Mediating Role of Creatinine by Qian W, Xu B, Fang Y, Wu X

“…Wen Qian,1,* Binkai Xu,2,* Yuan Fang,1 Xian Wu1 1Department of Operation, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center of Nanjing Medical University, Changzhou, Jiangsu Province, People’s Republic of China; 2Department of Surgery, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center of Nanjing Medical University, Changzhou, Jiangsu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xian Wu, Email wxcz0519@163.comObjective: To investigate the association between hysterectomy and accelerated aging, with a focus on the mediating effect of renal function and protective role of dietary fiber intake.Methods: The cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2010. …”
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IL-6 and CD4+/CD8+ are Important Indicators for Predicting Prognosis in Elderly AECOPD Patients: A Retrospective Study by Liu Q, Wang Y, Cao X, Zhang S, Xie J

“…Qingqing Liu,1,2,* Yanhui Wang,1,2,* Xueshuai Cao,1,2 Shan Zhang,1,2 Juan Xie1,2 1Department of General Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, People’s Republic of China; 2Center of Community-Based Health Research, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Juan Xie, Email abclux@126.comPurpose: Evaluating the role of IL-6 and CD4+/CD8+ in predicting the prognosis of elderly patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Patients and Methods: This study retrospectively enrolled 413 elderly patients who were hospitalized for AECOPD between January 2019 and December 2021. …”
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A Nomogram for Predicting Survival in Patients with SARS-CoV-2 Omicron Variant Pneumonia Based on Admission Data by Yang Y, Li D, Nie J, Wang J, Huang H, Hang X

“…This study aimed to develop a nomogram for predicting survival using chest computed tomography (CT) imaging features and laboratory test results based on admission data.Patients and Methods: A total of 436 patients with SARS-CoV-2 pneumonia (323 and 113 in the training and validation groups, respectively) were enrolled. …”
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Effects of Curcumin on Iron Overload in Rats by Gülüzar Özbolat, Arash Alizadeh Yegani

“…This study investigated the effects of curcumin on iron overload in rats. Methods: Forty male Wistar rats weighing 139.78 ± 11.95 gm (Mean ± SD) were divided into three equal groups: (i) controls; (ii) iron overload group that received six doses of iron dextran 1000 mg/kg–1 by intraperitoneal injections (i.p.); and (iii) iron overload curcumin group that received six doses of curcumin (1000 mg/kg BW by i.p.).  …”
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Availability of basic first aid training for cardiac arrest for people with disabilities by A. A. Birkun, Ye. A. Kosova, K. I. Redkokosh, A. S. Gapon

“…The aim was to study the digital accessibility (web accessibility) of massive open online courses in cardiopulmonary resuscitation (CPR) for PWD.Material and methods. A search was carried out for free English-language online courses teaching the principles and rules of providing first aid in cardiac arrest. …”
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Association of depression with sleep quality might be greater than that of pain intensity among outpatients with chronic low back pain by Wang H, Fu T, Hsu S, Hung C

“…This study aimed to investigate this issue.Patients and methods: A total of 225 outpatients with CLBP were enrolled from a general orthopedics clinic. …”
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Long-term results of elbow synovectomy and debridement in rheumatoid arthritis by Anastasia Aleksandrovna Roskidailo, S A Makarov, V N Amirdzhanova

“…Objective: to evaluate the efficiency of surgical treatment and the quality of life (QL) in patients with rheumatoid arthritis (RA) and elbow damage. Subjects and methods. Fifty-three patients who had undergone elbow synovectomy and debridement were examined 11±5.2 years postoper atively. …”
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Blood Eosinophil Count in Asthma Is Associated With Increased Abdominal Aortic Diameter and Increased Vascular Stiffness by Biener L, Budimovska A, Skowasch D, Pizarro C, Frisch BC, Nickenig G, Stumpf MJ, Schaefer CA, Schahab N

“…Blood eosinophil count (BEC) is implicated in both eosinophilic asthma and arterial wall inflammation.Objective: To explore the possible association of BEC in asthma and abdominal aortic artery changes.Methods: 112 outpatients were prospectively enrolled in this exploratory study. …”
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Effects of mini-dose esketamine–dexmedetomidine combination supplemented intravenous analgesia on postoperative sleep quality in elderly patients after total knee arthroplasty: a p... by Xiaoyan Wang, Xiaoli Ji, Jinfeng Liu, Caicai Liu, Yanhua Luo

“…However, the effectiveness of mini-dose esketamine–dexmedetomidine supplemented intravenous analgesia on postoperative sleep quality remains to be elucidated.Methods and analysis 110 elderly patients undergoing total knee arthroplasty will be randomly assigned to different regimens of patient-controlled intravenous analgesia with a total volume of 100 mL in either the experimental group (sufentanil 1.5 µg/kg+esketamine 25 mg+dexmedetomidine 100 µg) or the control group (sufentanil 1.5 µg/kg+equal vol of placebo, ie, saline). …”
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Nanotherapeutics for Macrophage Network Modulation in Tumor Microenvironments: Targets and Tools by Li R, Huang J, Wei Y, Wang Y, Lu C, Liu J, Ma X

“…In conclusion, nanotherapeutics targeting macrophages remains immense potential for the development of macrophage-mediated tumor treatment methods and will further enhance our understanding, diagnosis, and treatment of various malignants.Keywords: engineered macrophages, nanomedicine, cancer therapy, anti-tumor immunity…”
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The Application and Efficacy of Medication Safety Officer-Based Multidisciplinary Management in Reducing Adverse Drug Reaction and Improving Intravenous Management by Zhang X, Yan M, Qu X, Li Y, Liu L, Liu C

“…This study evaluates the effectiveness of medication safety officer (MSO)-based multidisciplinary management on managing IV fluids in children’s outpatient and emergency departments, aiming to reduce adverse drug reaction (ADR) and standardize IV infusion management.Methods: Implementing MSO-based multidisciplinary management integrates multidisciplinary supervision, information system optimization, and fostering medication safety culture. …”
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Using a Systems Thinking Approach to Increase Coastal Community Resilience against Environmental Shocks: A Case Study of Valiathura Coastal Area, India by Baker Matovu, Meltem Alkoyak-Yildiz, Isaac Lukambagire, Linda A. Etta, Yasin Bbira, Expedito Nuwategeka

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Hippocampal Anti-inflammatory Effect of Electroacupuncture at Baihui and Shenting on Cognitive Dysfunction Induced by Systemic Inflammation by CHEN Xiaomei, PANG Lina, WANG Zhifu

“…ObjectiveTo investigate the hippocampal anti-inflammatory mechanism of electroacupuncture at Baihui and Shenting on cognitive dysfunction induced by Lipopolysaccharide (LPS) intraperitoneal injection.MethodsA total of 45 clean grade adult C57BL/6 male mice (bodyweight 18-22 g) were randomly divided into control group, endotoxic brain injury group (model group) and endotoxic brain injury + electroacupuncture group (EA group). …”
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The sero-prevalence of brucellosis in cattle and their herders in Bahr el Ghazal region, South Sudan. by Nuol Aywel Madut, Adrian Muwonge, George William Nasinyama, John Bwalya Muma, Jacques Godfroid, Ambrose Samuel Jubara, James Muleme, Clovice Kankya

“…The bovine sero-prevalence was approximately equally distributed among the male 30.4% (26.9-34.2) and the females 32.5% (26.8-38.7). …”
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Comparison of Learning Curves and Clinical Outcomes in Unilateral Biportal Endoscopic Spinal Surgery Versus Percutaneous Transforaminal Endoscopic Surgery: A Cumulative Sum Analysi... by Yuan S, Chen R, Mei Y, Fan N, Wang T, Wang A, Du P, Xi Y, Zang L

“…This study aimed to evaluate the learning curves for unilateral biportal endoscopic spinal surgery (UBESS) and percutaneous transforaminal endoscopic surgery (PTES) by performing cumulative sum (CUSUM) analysis and to assess their efficacies in managing degenerative spinal diseases.Patients and Methods: This retrospective cohort study included 100 consecutive patients who underwent PTES and 100 consecutive patients who received UBESS. …”
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Effect of oral health education model on tooth brushing behavior and oral hygiene among children with intellectual disabilities by Muhammad Fiqih Sabilillah, Hari Kusnanto, Lisdrianto Hanindriyo, Sri Kuswandari

“… Objective: The aim of this study was to evaluate the effectiveness of an oral health education model in improving tooth brushing behavior and oral hygiene among children with intellectual disabilities. Material and Methods: This study used a quasi-experimental design with a pretest-posttest control group. …”
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A safety review and meta-analyses of bevacizumab and ranibizumab: off-label versus goldstandard. by Christine Schmucker, Christoph Ehlken, Hansjuergen T Agostini, Gerd Antes, Gerta Ruecker, Monika Lelgemann, Yoon K Loke

“…<h4>Background</h4>We set out a systemic review to evaluate whether off-label bevacizumab is as safe as licensed ranibizumab, and whether bevacizumab can be justifiably offered to patients as a treatment for age-related macular degeneration with robust evidence of no differential risk.<h4>Methods and findings</h4>Medline, Embase and the Cochrane Library were searched with no limitations of language and year of publication. …”
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