Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery by Roberto Visentin, Katrine Brodersen, Bjørn Richelsen, Niels Møller, Chiara Dalla Man, Andreas Kristian Pedersen, Jan Abrahamsen, Jens Juul Holst, Michael Festersen Nielsen

“…Two months after surgery, insulin secretion (p<0.05) and glucose effectiveness both improved equally in the two groups (11%, RYGB (p<0.01); 8%, SG (p>0.05)), whereas insulin sensitivity remained virtually unaltered. …”
Get full text

Gender-related differences in care-seeking behaviour for newborns: a systematic review of the evidence in South Asia by Sharif A. Ismail, Amy McCullough, Sufang Guo, Alyssa Sharkey, Sheeba Harma, Paul Rutter

“…We reviewed evidence on sex and gender differences in care-seeking behaviour for neonates as a driver for this.Methods We conducted a systematic review of literature published between January 1st, 1996 and August 31st, 2016 in Pubmed, Embase, Eldis and Imsear databases, supplemented by grey literature searches. …”
Get full text

Exploring spousal disparities: Age, earnings, and education as predictors of intimate partner violence in 29 developing countries by Rafi Amir-ud-Din, Rubina Idrees, Javaria Farooqui, Abdus Sattar Abbasi

“…Conclusion: The findings underscore the need for targeted policies to prevent IPV, particularly in low- and middle-income countries, by addressing spousal disparities in age, earnings, and education to promote gender equality.…”
Get full text

Cellular and molecular screening of connective tissue dysplasia in adolescent athletes (pilot study) by M. V. Dvornichenko, A. E. Sizikova, T. V. Saprina, E. N. Pashkova, M. S. Shcherbinko, I. A. Khlusov, V. V. Novitsky

“…The purpose of the study is to evaluate the cellular and molecular parameters of bone remodeling in the blood as potential markers of undifferentiated forms of connective tissue dysplasiaMaterials and methods. The structural and functional status of cellular elements of in vitro culturing of mononuclear leukocytes of peripheral blood in adolescent athletes connected with phenotypic manifestations of undifferentiated connective tissue dysplasia (UCTD) were investigated. 25 pupils of sport schools from 10–14 years old (main disciplines: figure skating, gymnastics, athletics) were examined with the help of express analysis. …”
Get full text

Altered Neuroplasticity in Epilepsy is Associated with Neuroinflammation and Oxidative Stress: In vivo Evidence of Brain-Derived Extracellular Vesicles by Wang S, Zhang H, Li R, Liu Z, Xiang D

“…While preclinical studies implicate neuroinflammation and oxidative stress in epilepsy-associated neuroplasticity, in vivo molecular-level evidence in humans is lacking.Patients and Methods: We used astrocyte-derived extracellular vesicles (ADEVs) and neuron-derived extracellular vesicles (NDEVs) as brain-derived biomarkers to explore biomarkers of neuroplasticity, neuroinflammation, and oxidative stress. …”
Get full text

Promising Response to Neoadjuvant Chemotherapy Plus Immunotherapy in Metaplastic Breast Carcinoma by Tan Q, Li N, Wang Y, Du T, Liang G, Zhao Z, Tang J, Wu H

“…This study aimed to evaluate the efficacy of combining NAC with immune checkpoint inhibitors (ICIs) in MpBC patients.Methods: We conducted a retrospective analysis of MpBC patients treated with NAC, with or without the addition of immunotherapy, at Sun Yat-sen university Cancer center between 2017 and 2024. …”
Get full text

First Experience in Small Incision Lenticule Extraction with the Femto LDV Z8 and Lenticule Evaluation Using Scanning Electron Microscopy by Mengmeng Wang, Fengju Zhang, Christine Carole Copruz, Longhui Han

“…To evaluate the specifications and technique properties of the new Femto LDV Z8 in creating intrastromal refractive lenticules during small incision lenticule extraction (SMILE). Methods. Six enucleated porcine eyeballs were equally divided into two groups (Femto LDV Z8 or VisuMax) and were randomly assigned to three experienced refractive surgeons who performed SMILE on each group. …”
Get full text

Demographic profile of pediatric malignancies in Himachal Pradesh by Anupam Badhan, Parveen Bhardwaj, Vijay Yadav, Neelam Grover, Rajeev Kumar Seem

“…Acute lymphoblastic leukemia was the most common hematological malignancy noted in 22.58%, followed equally by Hodgkin's disease and non-Hodgkin's lymphoma (20% of total hematological malignancies). …”
Get full text

Effects of bioactive peptides combined with probiotics on serum uric acid in patients with hyperuricemia by HAN Dan，ZHAO Ya，HUANG Enshan，YE Shuhua，WANG Wanjin，WU Fangmin，WANG Dingliang，ZHANG Ronghua

“…Objective: To evaluate the effect of bioactive peptides combined with probiotics on serum uric acid (SUA) in patients with hyperuricemia (HUA), so as to provide the evidence for prevention and treatment of HUA. Methods: The patients with HUA aged 18 to 65 years were selected and randomly divided into an intervention group and a control group. …”
Get full text

Comparison of active tuberculosis occurrence associated with Janus kinase inhibitors and biological DMARDs in rheumatoid arthritis by Jin-Won Kwon, Yun-Kyoung Song, Jaehee Lee, Junwoo Jo

“…Objectives This study aimed to evaluate the risk of tuberculosis associated with the use of Janus kinase (JAK) inhibitors or biological disease-modifying antirheumatic drugs (bDMARDs) in patients diagnosed with rheumatoid arthritis (RA) in South Korea.Methods In this nationwide matched-cohort study, we retrospectively identified adult patients with new-onset RA from the National Health Insurance Service database who were prescribed bDMARDs or JAK inhibitors and recently underwent latent tuberculosis infection (LTBI) screening during 2012‒2021, and followed them up until the end of 2022 for the development of active tuberculosis. …”
Get full text

Depictions of older adults residing in nursing homes: a Goffman-inspired thematic analysis of children’s picture books in a Danish context by Stinne Glasdam, Ragnhild Julante Andersen Gulestø, Christie Stilwell

“…Older adult characters were often depicted as equals to children, while the middle generation functioned as a bridge between generations without much interaction with older adults. …”
Get full text

The influence of an interactive educational approach on advance care planning counseling in individuals with psychiatric disorders by Yi-Chien Chen, Fang-Ying Chu, Ling-Yu Chang, Ming-Yuan Hsieh, Chao-Hsien Lee

“…This research explores the influence of an interactive educational approach on the ACP process for psychiatric patients and whether this approach can enhance their comprehension, attitudes, and intentions regarding Advance Decisions (AD). Methods To accommodate potential variances and ensure robustness in our findings, we ultimately elected to recruit 90 participants. …”
Get full text

Academic Pressure and Psychological Imbalance in High School Students: Predictors of Depression via Polynomial Regression and Response Surface Analysis by Ye Y, Zhang Z, Tao Z, Liping C, Wang Y, Chen H, Li S, Chen X, Tang H, Zhou J, Zhou J

“…Yanyue Ye,1,&ast; Zheng Zhang,1,&ast; Zhen Tao,3 Cui Liping,2 Yuxin Wang,1 Hui Chen,1 Sihong Li,1 Xianliang Chen,1 Huajia Tang,1 Jiawei Zhou,1 Jiansong Zhou1,&ast; 1Department of Psychiatry, the Second Xiangya Hospital of Central South University, National Center for Mental Disorders, National Clinical Research Center for Mental Disorders, Changsha, People’s Republic of China; 2Department of Psychiatry, Liuyang Brain Hospital, Liuyang, People’s Republic of China; 3Human Resources Department, Hebei Vocational University of Technology and Engineering, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jiansong Zhou, Email zhoujs2003@csu.edu.cnObjective: The purpose of this study was to explore how the congruence between academic pressure and psychological imbalance affects depressive symptoms in adolescents and to further explore grade-level differences in these effects among high school students.Methods: The study population consisted of 29,975 high school students from 20 schools in Liuyang City, Hunan Province. …”
Get full text

Comparative analysis of early outcomes of the first 150 cases of posterior approach robotic‐assisted radical prostatectomy and identification of the learning curve: A single‐surgeo... by Li June Tay, Henry Y. C. Pan, Leigh James Spurling, Philip Dundee

“…Abstract Objectives To report intraoperative and early postoperative outcomes of posterior approach Robotic Assisted Radical Prostatectomy (RARP) patients and analyse a single‐surgeon learning curve. Patients & Methods The initial 150 patients undergoing posterior approach RARP by a single surgeon were analysed in three equal cohorts. …”
Get full text

Efficacy of the combination of tadalafil and tamsulosin versus tadalafil alone as a medical expulsive therapy for stone L1/3 ureter 10 mm or less: A prospective comparative placebo... by Ahmed Reda, Mostafa Kamel, Mohamed Loay, Yaser M. Abdelsalam, Mohamed A. Zarzour

“…We aimed to compare the combination of tadalafil and tamsulosin versus tadalafil alone as MET for stones in the L1/3 ureter of 10 mm or less. Materials and methods. A total of 150 patients with L1/3 ureteric stones measuring 10 mm or less were enrolled in the study and randomly assigned to one of 3 equal groups using a computer-generated random number. …”
Get full text

Comparative Evaluation of the Defocus Curve of Monofocal IOL, Extended Depth of Focus IOL, and Trifocal IOL by M. E. Konovalov, A. V. Morenko

“…Comparative evaluation of the defocus curve (DC) of monofocal IOLs (MIOLs), extended depth of focus IOLs (EDОF) and trifocal IOLs (TIOLs). Patients and methods. We observed 90 patients (average age 57.8 ± 1.8 years) who underwent standard binocular phacoemulsification of cataracts in both eyes with emmetropic “target” refraction and postoperative monocular uncorrected distance visual acuity (UCVA) of at least 1.0 rel. units. …”
Get full text

Risk factors of cerebral complications after cardiac surgery by L. M. Tibekina, E. G. Smertina, V. D. Zolotov, A. O. Zaitseva, A. P. Kretsu, M. S. Stolyarov, M. S. Kamenskikh, M. V. Starosotskaya, D. V. Shmatov

“…The authors defined the risk factors of cerebral complications after cadiosurgical operations. MATERIAL AND METHODS. The patients with ischemic heart disease who underwent coronary artery bypass grafting (CABG) were included in the first group (n=189) 132 (69,8 %) men and 57 (30,2 %) women aged 62,5 ± 8,3 years old. …”
Get full text

The Nb4C3 MXenzyme Attenuates MASH by Scavenging ROS in a Mouse Model by He S, Lv Y, Gao Z, Peng L

“…However, treating MASH remains a challenge.Methods: Two-dimensional (2D) niobium carbide (Nb4C3) MXene nanoenzymes (MXenzymes) possess both antioxidant and anti-inflammatory properties and have attracted considerable attention in the tumor and engineering fields. …”
Get full text

A Comparative Study between Ultrasound Cycloplasty and Cyclocryotherapy for the Treatment of Neovascular Glaucoma by Wang Ruixue, Wang Tao, Li Ning

“…To compare the clinical efficacy, safety, and histological effect between ultrasound cycloplasty (UCP) and cyclocryotherapy in the treatment of neovascular glaucoma. Methods. Two groups of neovascular glaucoma patients who underwent two types of treatment, respectively, namely, 26 patients treated by UCP and 23 by cyclocryotherapy, were treated and observed during the clinical study for six months. …”
Get full text

DYNAMICS OF OBSERVED AND RELATIVE SURVIVAL OF PATIENTS WITH PRIMARY LIVER CANCER ON THE POPULATION LEVEL ACCORDING TO DISEASE STAGE AND HISTOLOGICAL STRUCTURE by V. M. Merabishvili, O. f Chepik, E. N. Merabishvili

“…Also it was necessary to estimate a number of analytical indicators, which reflect the state of problem. Material and methods. To solve this purpose there were studied the state of problem in European registries, data on state reporting of Russia and primary materials of the Population-Based Cancer Registry of St. …”
Get full text