A Nomogram for Predicting Overall Survival in Primary Central Nervous System Lymphoma: A Retrospective Study by Ling Y, Miao X, Zhou X, Ma J, Lin Z, Li Q, Zhang M, Ma Y, Chen B

“…This study aimed to develop a novel prognostic model based on real clinical data and compare it with existing systems.Patients and Methods: A total of 288 patients newly diagnosed with PCNSL were recruited. …”
Get full text

Reduction of death anxiety in patients with advanced cancer in short-term psychotherapy by Paula Oberth, Franziska Springer, Antje Lehmann-Laue, Anja Mehnert-Theuerkauf

“…The active control group, a non-specific psychotherapeutic counselling intervention (SPI), showed equal effects on depression and distress and consequently both groups are investigated together in this study. …”
Get full text

Caregiver-Reported ADHD in Shanghai, China: Prevalence, Associated Factors, and Implications for Diagnosis by Wang S, Zhang M, Huang L, Zhang X, Xue Z

“…This study aimed to examine the prevalence of caregiver-reported ADHD in Shanghai, China, and identify associated factors.Patients and Methods: A cross-sectional survey was conducted in Jiading District, Shanghai, targeting caregivers of children and adolescents attending elementary, middle, and high schools. …”
Get full text

Evaluation and Comparison of the Academic Quality of Open-Access Mega Journals and Authoritative Journals: Disruptive Innovation Evaluation by Yuyan Jiang, Xue-li Liu, Liyun Wang

“…However, the absolute number was roughly equal to that of authoritative journals. OAMJs surpassed authoritative journals in publishing innovative papers in 24 research directions (eg, Allergy), accounting for 40.68% of all research directions in clinical medicine. …”
Get full text

Does bladder outflow obstruction obfuscate the traditional clinical factors that are used to assess the risk of prostate cancer at rapid‐access diagnostic clinics? by Thomas Philip Cahill, Samuel Joseph Withey, Steve Hazell, Declan Cahill, Netty Kinsella

“…This will help facilitate effective and evidence‐based triaging of patients in rapid‐access clinics. Materials and Methods We retrospectively analysed prospectively collected data from 307 suspected prostate cancer patients who underwent diagnostic biopsy from 2019 to 2023 at a single, high‐volume, specialist cancer centre. …”
Get full text

Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta... by Rui Li, Laichun Lu, Yu Lin, Mingxia Wang, Xin Liu

“…The aim of this study was to compare the efficacy and safety of metronidazole monotherapy with vancomycin monotherapy and combination therapy in CDI patients.<h4>Methods</h4>A comprehensive search without publication status or other restrictions was conducted. …”
Get full text

Orthovoltage x-ray therapy significantly reduces disability risk in knee osteoarthritis patients: A decade-long cohort study by Maria V. Makarova, Mikhail Yu. Valkov, Andrey М. Grjibovski

“…A total of 292 patients were randomly distributed among two groups of equal sizes. The control group received combination therapy with NSAIDs and SYSADOA. …”
Get full text

TRIMETAZIDINE INFLUENCE ON FILTRATION AND TUBULOINTERSTITIAL FUNCTION OF KIDNEYS IN ISCHEMIC HEART DISEASE PATIENTS WITH CHRONIC HEART FAILURE AND RENAL DYSFUNCTION by N. A. Koziolova, I. I. Kolegova, M. V. Surovtseva

“…All CHF and stage 3 CKD patients were randomized to equal 2 groups depending on the kind of treatment. …”
Get full text

Mortality in the Volgograd Region Against the COVID-19 Pandemic by A. V. Alpatov

“…Estimation of excess mortality was carried out taking into account the dynamics of age-specific mortality rates.Materials and methods. The main sources of information for the study of mortality were the Russian database on fertility and mortality and Rosstat data. …”
Get full text

Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions by Wu S, Zhou Z, Li Y, Wu R, Jiang J

“…This study delves into the role of quercetin-pretreated MSC-derived exosomes (MSCsQr-exo) in accelerating the healing of diabetic wounds.Methods: MSCsQr-exo were isolated from quercetin-pretreated MSCs and applied to fibroblasts to evaluate changes in cell function. …”
Get full text

PREDICTION OF THE INFLUENCE OF ORIGINAL AND GENERIC ROSUVASTATIN ON DIRECT MEDICAL COSTS OF SECONDARY PREVENTION IN PATIENTS WITH CHRONIC TYPES OF ISCHEMIC HEART DISEASE by E. I. Tarlovskaya, G. I. Nechaeva, S. V. Malchikova, А. А. Semenkin

“…To study therapeutic equivalence of rosuvastatin generic and original medication and to conduct the pharmacoeconomic analysis to compare the impact of the drug on direct expenses in secondary prevention for the patients with chronic ischemic heart disease (CHD). Material and methods. The open label, prospective observational study performed with the switch of medication, that included 38 patients with chronic CHD and duration of 6 months. …”
Get full text

Analysis and Validation of a Diagnostic Nomogram for Predicting the Risk of Acute Respiratory Failure for Non-HIV Related Pneumocystis Jirovecii Pneumonia Patients by Bian W, Xin Y, Bao J, Gong P, Li R, Wang K, Xi W, Chen Y, Ni W, Gao Z

“…In this article, we explore the risk factors of ARF and propose a prognostic model of ARF for PCP patients.Methods: In this multi-center, retrospective study in 6 secondary or tertiary academic hospitals in China, 120 PCP patients were screened from the Dryad database for the development of a predictive model. …”
Get full text

Comparison of laparoscopic surgical skills acquired on a virtual reality simulator and a box trainer: an analysis for obstetrics-gynecology residents by M. Varras, C. Loukas, N. Nikiteas, V.K. Varra, F.N. Varra, E. Georgiou

“…The aim of this study was to compare the training efficacy of virtual reality (VR) simulators and box-trainers (BTs) for skills acquisition in gynecologic surgery, and also to study the transferability of these skills in the performance of more advanced gynecologic operations. Methods: Twenty residents in obstetrics-gynecology with minimal laparoscopic experience were randomized into two equal groups to be trained on either a VR simulator (Group-A) or a BT (Group-B). …”
Get full text

EPIDEMIOLOGY OF MALIGNANT TUMORS OF LARGE SALIVARY GLANDS (POPULATION-BASED STUDY) by V. M. Merabishvili, O. F. Chepik, E. N. Merabishvili

“…These values were 0000 equal to 0.7 and 0.4 0/ in Russia (2014), and 0.6 and 0.5 0/ in St. …”
Get full text

Serum afamin levels in women with polycystic ovary syndrome by Md. Jaminur Rashid, Md. Shahed-Morshed, Hurjahan Banu, Muhammad Abul Hasanat

“…This study aimed to assess the diagnostic performance of serum afamin in PCOS and the association of IR and metabolic syndrome (MS) in patients versus controls. Methods: This cross-sectional study included 40 women with PCOS based on the International Evidence-based Guideline, 2018, and an equal number of matched healthy controls from a university hospital between July 2020 and September 2021. …”
Get full text

Cost‐Effectiveness of Computer‐Assisted Cytology in a Primary hrHPV‐Based Cervical Cancer Screening Programme by Ellen M. G. Olthof, S. Kaljouw, Folkert J. vanKemenade, Anne M. Uyterlinde, Inge M. C. M. deKok

“…ABSTRACT Background Computer‐assisted screening (CAS) shows equal performance compared to manual screening, although results are heterogeneous. …”
Get full text

Treating overactive bladder symptoms after transurethral prostatic surgery for benign prostatic hyperplasia – Which medication to choose? by Cheng-Ling Lee, Hann-Chorng Kuo

“…Conclusion: Solifenacin and mirabegron are two different drug classes both equally effective in treating immediate OAB symptoms after TUR-P or TUI-P. …”
Get full text

Accuracy of physician self‐estimation of time spent during patient care in the emergency department by Martin A. Reznek, Virginia Mangolds, Kevin A. Kotkowski, Kian D. Samadian, James Joseph, Celine Larkin

“…Direct observation is time consuming and cost prohibitive, so we sought to determine if physician self‐estimation of time spent during patient care was accurate. Methods We performed a prospective, convenience‐sample study in which research assistants measured time spent by ED physicians in patient care. …”
Get full text

Comparative evaluation of push-out bond strength after root perforation repair using recently introduced bioceramic and calcium silicate-based materials – An in vitro study by Gurinder Kaur, Deepak Kurup, Deepyanti Dubey, Ajit Hindlekar, Ganesh Ranganath Jadhav, Priya Mittal, Siddharth Shinde

“…Aim: This study was planned to comparatively evaluate the push-out bond strength (PBS) after perforation (PF) repair using mineral trioxide aggregate (MTA) repair high plasticity (HP), Biodentine, and EndoSequence Bioceramic (BC) root repair material (ERRM). Methods: Ninety freshly extracted, intact, human molars were collected. …”
Get full text

Development and Characterization of 4A7: A High-Affinity Monoclonal Antibody Targeting Claudin18.2 by Wu Y, Tian J, Zhou Y, Zhang R, Gao X, Luo L

“…However, patients with advanced, unresectable, or metastatic GC or PC face poor prognoses, highlighting the urgent need for more effective Claudin18.2-targeted therapies.Methods and Results: We developed 4A7, a fully human monoclonal antibody with superior affinity and specificity for Claudin18.2, using a rigorous positive and negative screening strategy to eliminate cross-reactivity with Claudin18.1. …”
Get full text