Identification of ZNF652 as a Diagnostic and Therapeutic Target in Osteoarthritis Using Machine Learning by Chen Y, Liang R, Zheng X, Fang D, Lu WW, Chen Y

“…The DEGs were discerned using three distinct machine learning methods. The accuracy of these DEGs in diagnosing OA was evaluated using the Receiver Operating Characteristic (ROC) Curve. …”
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Causal Relationship Between Psychosocial Factors and Neck Pain: A Two-Sample Mendelian Randomization Study by Liang H, Wu Q, Yang S, Zhang S, Miao J, Jin H, Wang X

“…This study aimed to investigate whether potential risk factors have a causal effect on NP at the genetic level using a two-sample Mendelian randomization (MR) analysis.Methods: Summary-level data for potential risk factors, including distress, anxiety disorder, depression, mood, sleep disorder, loneliness, education, alcohol consumption, smoking, time spent using the computer, and physical activity, as well as NP, were obtained from multiple large-scale Genome-Wide Association Studies (GWAS). …”
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Exploring the Association Between Triglyceride-Glucose Indices and Their Derivatives With Obstructive Sleep Apnea: Insights From the National Health and Nutrition Examination Surve... by Zhou Y, Xue F

“…Yating Zhou,* Fei Xue* Kunshan Hospital of Traditional Chinese Medicine, Kunshan City, Suzhou, Jiangsu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Xue, Department of Surgery, Kunshan Hospital of Traditional Chinese Medicine, Zuchongzhi South Road, Kunshan City, Suzhou, Jiangsu, 215300, People’s Republic of China, Email 2090168460@qq.comBackground: Simple and affordable methods for evaluating Insulin Resistance (IR) have been suggested, such as the Triglyceride-Glucose (TyG) index and its variants, including the TyG-Body Mass Index (TyG-BMI), TyG-Waist Circumference (TyG-WC), and TyG-Waist-to-Height Ratio (TyG-WHtR). …”
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Prognostic Value of Four Objective Nutritional Indices in Predicting Long-Term Prognosis in Elderly Patients with Atrial Fibrillation: A Retrospective Cohort Study by He Q, Fan X, Li B, He Q, Cao Y, Zhang H

“…Qingwei He,1,* Xingman Fan,2,3,* Bowen Li,3 Qiongyi He,1 Yukun Cao,2 Haitao Zhang1,2 1The Fifth School of Clinical Medicine, Air Force Clinical Medical School, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China; 2Department of Cardiology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, People’s Republic of China; 3Graduate School, Hebei North University, Zhangjiakou, Hebei, 075000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haitao Zhang; Yukun Cao, Email kjzht@sina.com; caoyukuntg@163.comBackground: Several objective and comprehensive nutritional assessment methods have been used for predicting adverse outcomes in elderly patients with various diseases. …”
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Assessment of the Myocardial Stress Biomarker NT-proBNP in Real Clinical Practice by I. A. Kozlov, D. A. Sokolov

“…Subjects and Methods. The study involved 35 vascular surgery patients of varying degrees of cardiological risk. …”
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Macrophage Infiltration Correlated with IFI16, EGR1 and MX1 Expression in Renal Tubular Epithelial Cells Within Lupus Nephritis-Associated Tubulointerstitial Injury via Bioinformat... by Tian M, Tang M, Chen C, Lin Y, Chen H, Xu Y

“…Ming Tian,1,2,* Min Tang,1,2,* Caiming Chen,1– 3,* Yufang Lin,1,2 Hong Chen,4 Yanfang Xu1– 3 1Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China; 2Fujian Clinical Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China; 3Department of Nephrology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, People’s Republic of China; 4Department of Pathology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Chen; Yanfang Xu, Email fychenhong@126.com; xuyanfang99@hotmail.comObjective: A comprehensive bioinformatics analysis was conducted to investigate potential new diagnostic biomarkers and immune infiltration characteristics associated with tubulointerstitial injury in lupus nephritis (LN), and to examine possible correlations between key genes and infiltrating immune cells.Methods: The GSE32591, GSE113342, and GSE200306 datasets were downloaded from the Gene Expression Omnibus database and differentially expressed genes (DEGs) were identified in the pooled dataset. …”
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Identification of Potential Drug Targets for the Treatment of Severe Burn Wounds from a Multi-Omics Perspective by Zhu G, Li J, Xu J, Guo G, Zhu F

“…Despite improvements in the treatment of burn patients due to advancements in materials and techniques, there remains a need for novel therapeutic approaches to enhance burn prognosis further.Patients and Methods: Several types of genomic methods are used in this study, such as differential gene expression analysis, weighted gene co-expression network analysis (WGCNA), machine learning, and Mendelian randomization (MR), to find genes that are linked to severe burns and create a diagnostic nomogram to see how well these genes can predict severe burns. …”
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ORGANIZATIONAL ISSUES OF CARDIOREHABILITATION SERVICE IN RUSSIA. THE RESULTS OF PILOT PROJECT “DEVELOPMENT OF REHABILITATION SYSTEM OF CARDIOVASCULAR PATIENTS IN MEDICAL INSTITUTIO... by D. M. Aronov, M. G. Bubnova, S. A. Boytsov, G. Е. Ivanova, A. G. Andreev, О. L. Barbarash, V. V. Belova, V. N. Belov, B. V. Borisov, Е. V. Ivanov, I. М. Karamova, A. V. Karpukhin, V. B. Krasnitskiy, Е. S. Kyblanova, P. А. Lebedev, Е. А. Lisnyak, N. P. Lyamina, Т. N. Mizurova, О. F. Misyura, I. E. Mishina, О. V. Mischenko, S. Yu. Nikulina, N. I. Ostroushko, S. А. Poteshkina, А. S. Sidorov, А. А. Sprikut, I. S. Sukhinina, А. G. Tkacheva, S. А. Ustyugov, G. А. Chumakova

“…To analyze,  how is, under  the  framework of the  Pilot Project, organized and being conducted  the improvement of work of the known departments in exact medical institutions (MI) of RF for rehabilitation of cardiovascular  diseases (CVD) patients  at the  three  steps  under  the current “Order of medical care and medical rehabilitation”, and how do the scientifically proven and types and methods  of cardiorehabilitation (CR) being implemented,  and to try to elaborate  on an exact algorithm for patients course.Material and methods. …”
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Intervention effect and mechanism of Dracocephalum moldavica L. extract on bleomycin-induced pulmonary fibrosis in rats by Xiaoyu SUN, Li CHEN, Ruifang GAO, Hui YU, Min JIN

“…A rat model of pulmonary fibrosis was constructed using bleomycin (5 mg·kg−1) intratracheal instillation, and an equal volume of saline was instilled into the control group. …”
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Conventional and Conformal Radiotherapy with and without Beam Intensity Modulation in Patients with Stage II Hodgkin’s Lymphoma with Supradiaphragmal Lesions by YuN Vinogradova, EI Ivanova, AI Chumachenko, EV Smirnova, GI Andreev, AM Kalesnik, NA Vorob’ev, NV Il’in

“…Overall 5- and 10-year survival (OS) was equal and accounted for 98.0 ± 1.4 %, the disease-free survival (DFS) was also equal between groups and accounted for 85.9 ± 1.3 %. …”
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A Comparative Analysis of Energy Efficiency of Two Sprinkler Irrigation Systems for Wheat Cultivation (Case Study: Dehgolan Plains, Kurdistan) by P. Tahmasbi, F. Dalvand, S.A. Hosseini, B. Karimi, H. Ghadrshnas

“…Moreover, the energy productivity and efficiency of the two systems were almost equal as well as the net energy of irrigation system (1) and irrigation system (2) was 41510.96 and 64156.03 MJ ha-1, respectively. …”
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A holistic approach to childhood trauma: assessing the role of Adlerian therapy in post-hospitalisation recovery by Samaran Elisabeth, Cherry Mustamu Alva, Difran Nobel Bistara, Susanti Susanti, Suryo Putro Waskito Aji, Hasim Nur Hafni

“…Participants were equally divided into intervention (Adlerian therapy) and control (play therapy) groups, receiving therapy over four weeks. …”
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Ipomoea batatas (L.) Lam. cultivation in the conditions of light culture in vitro and ex vitro by E. A. Kalashnikova, R. N. Kirakosyan, A. V. Gushchin, K. G. Abubakarov, N. N. Sleptsov, S. K. Temirbekova, A. P. Glinushkin, O. V. Meleshina, N. Ya. Rebouh, M. M. Tareeva

“…Cellular biotechnology is aimed at solving this problem using methods of clonal microreproduction, cell selection, somatic hybridization, etc. …”
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Women’s experiences of gender-based violence supports through an intersectional lens: a global scoping review by Amaya Perez-Brumer, Beverley M Essue, Cyndirela Chadambuka, Isabel Arruda-Caycho, Danielle Tocallino, Rebecca Balasa, Prossy Kiddu Namyalo, Carmina Ravanera, Sarah Kaplan

“…Most studies (60%) were published since 2015 and used qualitative methods (63%). Findings reflected intersectional differences in women’s experiences of accessing GBV services across contexts and lived experiences. …”
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Evaluating the anticancer efficacy of Chara vulgaris ethanolic extract and selenium nanoformulation in Ehrlich carcinoma mice: role of autophagy and apoptosis by Maha Alsunbul, Thanaa A. El-Masry, Maisra M. El-Bouseary, Enas I. El Zahaby, Mostafa M. El-Sheekh, Mohamed M. S. Gaballa, Eman Wahsh, Heba Kamel Badawy, Jawaher Abdullah Alamoudi, Reem ALQahtani, Naifa Alenazi, Maysa M. F. El-Nagar

“…The present work investigated the anticancer effect of ethanolic extract from Chara vulgaris (C. vulgaris) and its selenium nanoformulation (CvSeNPs) against solid Ehrlich carcinoma (SEC). Methods Gas chromatography-mass spectroscopy was used to analyze C. vulgaris, and many analytical methods were used to characterize the biosynthesized CvSeNPs, including zeta potential, particle size, polydispersity index (PDI), SEM, TEM, and FTIR. …”
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Weight management and its educational differences among retired individuals living with obesity—a salutogenic approach by Hilla Nordquist, Tea Lallukka, Jatta Valkonen, Anu Joki

“…Half of the interviewees had a low level of education, and the other half had a high level of education. Women and men were equally represented. We analyzed the data using a deductive-inductive content analysis. …”
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Do We Have a Place for Non-Steroidal Anti-Inflammatory Drugs in Corneal Refractive Surgery? by N. V. Maychuk, I. A. Mushkova, M. R. Obraztsova

“…To study the clinical efficacy and safety of Broxinac (0.09 % bromfenac solution) in the early postoperative period of corneal refractive surgery.Materials and methods. The study included 168 patients (168 eyes) with moderate and high myopia after PRK (24 eyes), FemtoLASIK (78 eyes) and ReLEx SMILE (66 eyes), divided into equal subgroups: in the main group, Broxinac was instilled once 30 minutes after the operation, and in the control group — placebo. …”
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Microkeratome versus manually dissected donor tissue for Descemet stripping endothelial keratoplasty: A randomized prospective study by Ritu Mali, Smruti R. Priyadarshini, Srikant K. Sahu, Amrita Mohanty, Sujata Das

“…Purpose: To compare the visual outcomes, postoperative complications, and graft asymmetry between precut and manually dissected donor tissues for Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet stripping endothelial keratoplasty (DSEK) procedures, respectively. Methods: Seventy eyes of 70 patients undergoing DSEK/DSAEK at a tertiary eyecare center in eastern India were included in this prospective randomized control study. …”
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Does Health Education Through Videos and E-Leaflet Have a Good Influence on Improving Students’ Reproductive Health Knowledge, Attitudes, and Practices? an Intervention Study... by Yuliasih ND, Sari P, Bestari AD, Martini N, Sujatmiko B

“…The hypothesis for this study was to explore the differences in knowledge, attitudes, and practices before and after the intervention.Methods: This study used a quasi-experimental design. …”
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Characterisation of diabetic ketoacidosis in children and adolescents with type 1 diabetes: a regional hospital study by Sophy Korula, Sheikh Arif Maqbool Kozgar, Lloyd Bwanaisa

“…Abstract Aim To characterise the clinical and biochemical parameters of children (0–16 years) who presented with Diabetic Ketoacidosis (DKA) at a regional hospital in Australia. Methods A retrospective observational study was conducted following the approval of the Ethics Committee. …”
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