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  1. 6841

    Evaluation of Nosocomial Infection Management Efficiency Based on the Data Envelopment Analysis Model by Wang J, Wang G, Qi C

    Published 2025-04-01
    “…Jin Wang,1,* Gan Wang,2,3,* Chaoyi Qi4 1Department of Healthcare-associated Infection Management, Qingdao Municipal Hospital, Qingdao, People’s Republic of China; 2Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, People’s Republic of China; 3School of Public Health, Fudan University, Shanghai, People’s Republic of China; 4Department of Anorectal Surgery, Taian Hospital of Traditional Chinese Medicine, Taian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gan Wang, Email gwangqd@163.comBackground: This study used data envelopment analysis (DEA), to assess relative efficiency of infection control in different clinical departments of the hospital for performance evaluation purposes.Methods: All wards and departments from January to December 2022 were selected as decision units, and five input and two output indicators related to infection prevention and control were determined using DEA. …”
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  2. 6842

    Construction and Validation of a Nomogram Prediction Model for the Risk of Cefoperazone Sodium/Sulbactam Sodium-Related Coagulation Disorders by Min M, Zeng J, Zou M, Peng Y

    Published 2025-08-01
    “…Mengjun Min,1,* Jing Zeng,1,* Mingyue Zou,1 Yingxian Peng2 1Department of Pharmacy, The Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University, Wuhan, People’s Republic of China; 2Department of Pharmacy, Hubei No. 3 People’s Hospital of Jianghan University, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yingxian Peng, Hubei No. 3 People’s Hospital of Jianghan University, No. 26 Zhongshan Road, Qiaokou District, Wuhan, Hubei, 430033, People’s Republic of China, Email pyx0316@163.comObjective: To construct and validate a nomogram prediction model for the risk of cefoperazone sodium/sulbactam sodium (CPZ/SAM)-related coagulation disorders in hospitalized patients.Methods: Patients treated with CPZ/SAM from January 2022 to December 2024 were enrolled and divided into a coagulation disorder group and a control group based on the occurrence of coagulation disorders. …”
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  3. 6843
  4. 6844

    Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis. by James D Berry, Jeremy M Shefner, Robin Conwit, David Schoenfeld, Myles Keroack, Donna Felsenstein, Lisa Krivickas, William S David, Francine Vriesendorp, Alan Pestronk, James B Caress, Jonathan Katz, Ericka Simpson, Jeffrey Rosenfeld, Robert Pascuzzi, Jonathan Glass, Kourosh Rezania, Jeffrey D Rothstein, David J Greenblatt, Merit E Cudkowicz, Northeast ALS Consortium

    Published 2013-01-01
    “…Analysis of the pharmacokinetics, tolerability, and safety was used to determine the ceftriaxone dosage for Stage 3 efficacy testing.<h4>Methods</h4>In Stage 1, 66 subjects at ten clinical sites were enrolled and randomized equally into three study groups receiving intravenous placebo, ceftriaxone 2 grams daily or ceftriaxone 4 grams daily divided BID. …”
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  5. 6845

    Nerve Complications with Regional Anesthesia in Foot and Ankle Surgery Avoiding the Popliteal Fossa by Austin Gerwig MA, BS, Breanna Santoso, Maximilian George, Nicholas Cheney DO, FAOAO, Patrick O'Connor

    Published 2024-12-01
    “…An approach to block more distal nerves and avoid the popliteal fossa altogether may provide equal anesthetic and pain relief with fewer motor and sensory complications. …”
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  6. 6846

    Atelocollagen Injection Enhances the Healing of Nonoperatively Treated Achilles Tendon Tears by Jaehwang Song MD, PhD, Chan Kang MD, PhD, Seongkyeong Jo MS

    Published 2024-12-01
    “…The animals were equally divided into the noninjection group (NG) and the collagen injection group (CG). …”
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  7. 6847

    Clinical review of stroke care at National District Hospital, Bloemfontein by Selma Smit, Dirk T. Hagemeister, Cornel van Rooyen

    Published 2023-01-01
    “…The median age was 61 years (range 28–89 years), with an almost equal split between genders. The most common risk factor was hypertension (81.3%). …”
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  8. 6848

    Clustering analysis of 100-year international seismic catalogue for Azerbaijan by Т.Х. Бабаев, Я.Н. Алиев, Г.Р. Бабаев

    Published 2025-03-01
    “…The number of earthquakes with magnitude greater and equal to magnitude of completeness for cluster I and VI is 213 and 30 respectively. …”
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  9. 6849

    Tigulixostat Alleviates Hyperuricemic Nephropathy by Promoting M2 Macrophage Polarization by Xue L, Tao Q, Chang H, Yan S, Wang L, Zhao Z, Tu C

    Published 2025-01-01
    “…Currently, xanthine oxidase (XO) inhibitors are the predominant uric-lowering medications on the market.Methods: In this study, we utilized single-cell RNA sequencing, spatial metabolomics, plasma metabolomics, flow cytometry to explore the effects of Tigulixostat on uric acid level and hyperuricemic nephropathy (HN) in Uox-KO mouse model.Results: In this study, we discovered that Tigulixostat (LC350189) more effectively reduced SUA levels and resulted in better renal outcomes compared to allopurinol, without inducing liver injury in urate oxidase knockout (Uox-KO) mice. …”
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  10. 6850

    &ldquo;I Haven&rsquo;t Told Other People. I Want to Keep My Dignity&rdquo;: HIV Related Stigma Among the Elderly in Uganda by Nakasujja N, Nakigudde J, Lwanga IB, Sezibera V

    Published 2024-12-01
    “…We therefore explored issues related to disclosure of HIV status and HIV-related stigma in the elderly.Patients and Methods: This was an exploratory qualitative study, employing Straussian Grounded Theory. …”
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  11. 6851

    Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial by Mariam Dawoud, Maha Al-Husseiny, Omneya Helal, Moutaz Elsherbini, Mazen Abdel-Rasheed, Mona Sediek

    Published 2023-08-01
    “…Abstract Objective This study compares the effectiveness of administering sublingual misoprostol combined with oxytocin to that of IV tranexamic acid combined with oxytocin to reduce intra and post-operative blood loss in high-risk women for postpartum haemorrhage (PPH) following cesarean section (CS). Methods About 315 high-risk pregnant women undergoing CS participated in this trial. …”
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  12. 6852

    Exploring the Predictive Potential of Systemic Immune Inflammation Index and Hematologic Markers in Preterm Labor Risk Assessment by Sadullah Özkan, Yaprak Üstün

    Published 2025-04-01
    “…Objective: This study aimed to evaluate the potential association between the Systemic Immune Inflammation Index (SII) and preterm labor, given the growing interest in inflammatory biomarkers as possible predictors of pregnancy outcomes. Methods: Conducted as a retrospective observational study at University of Health Sciences Türkiye, Etlik Zübeyde Hanım Women`s Health and Research Hospital, the study included 200 participants, split equally between those with preterm labor and a control group with term births. …”
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  13. 6853

    Role of RAPID score and adjusted RAPID score in management of infected pleural effusion by Ahmed M. Amer, Azza A. El akhal

    Published 2025-04-01
    “…Diabetes mellitus (DM) was a predisposing factor for treatment failure at the cut-off value of RAPID score greater than or equal to 2, so the modified RAPID score had more value in the prediction of the outcome of medical treatment in infected pleural effusion. …”
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  14. 6854

    Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study by Feng S, Wang Y, Liu S, Zhang Y, He L

    Published 2025-02-01
    “…This study aims to explore these relationships using Mendelian Randomization (MR) analysis.Methods: Data from 191 resting-state functional MRI (rsfMRI) phenotypes and endometriosis genetic datasets were analyzed using both forward and reverse MR approaches. …”
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  15. 6855

    Global antibiotic dosing strategies in hospitalised children: Characterising variation and implications for harmonisation of international guidelines. by Michelle N Clements, Neal Russell, Julia A Bielicki, Sally Ellis, Silke Gastine, Yingfen Hsia, Joseph F Standing, A Sarah Walker, Mike Sharland

    Published 2021-01-01
    “…We investigated factors underlying variation in antibiotic dosing using data from five global point prevalence surveys.<h4>Methods & findings</h4>Data from 3,367 doses of the 16 most frequent intravenous antibiotics administered to children 1 month-12 years across 23 countries were analysed. …”
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  16. 6856

    Immediate consecutive microvascular decompression for bilateral classical trigeminal neuralgia by Mauro Alberto Segura-Lozano, Mario Alexis del Real-Gallegos, Pedro Mendoza-Lemus, Octavio Carranza-Rentería, Yael Rodrigo Torres-Torres, Alejandro González-Silva, Arturo Santoyo-Pantoja, Aarón Giovanni Munguía-Rodríguez

    Published 2024-11-01
    “…Microvascular decompression (MVD) is a well-established treatment for TN; however, the experience with immediate consecutive bilateral MVD procedures is limited and requires further evaluation.ObjectiveTo evaluate the safety and efficacy of immediate consecutive bilateral MVD in patients with severe BTN compared to non-consecutive bilateral MVD procedures.MethodsA retrospective analysis was conducted on 15 patients with BTN who underwent bilateral MVD. …”
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  17. 6857

    Risky sexual behaviour amidst predicament of acceptable sexually transmitted infection partner notification modalities: A cross-sectional survey amongst minibus taxi drivers in Gau... by Mathildah M. Mokgatle, Sphiwe Madiba

    Published 2020-12-01
    “…Conclusion: Preferred patient-initiated and provider-initiated PN was almost equal, hence, the provider-initiated PN should be augmented to support the current patient-initiated PN to increase the overall STI notification.…”
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  18. 6858

    Atopic Dermatitis and Psoriasis as Overlapping Syndromes by A. Bozek, M. Zajac, M. Krupka

    Published 2020-01-01
    “…This study aimed to present the clinical and immunological profiles of patients with concomitant AD and PS and compare them with those of patients with only one of the diseases. Methods. In this observational study, 38 children with concomitant AD and PS with a mean age of 6.5±3.2 yrs were compared with 41 similar patients with AD only (5.3±5.1 yrs) and 28 patients with PS only (6.4±4.3 yrs). …”
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  19. 6859

    Hand-arm vibration and the risk of vascular and neurological diseases-A systematic review and meta-analysis. by Tohr Nilsson, Jens Wahlström, Lage Burström

    Published 2017-01-01
    “…Moreover the aim was to estimate the magnitude of such an association using meta-analysis.<h4>Methods</h4>This systematic review covers the scientific literature up to January 2016. …”
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  20. 6860

    The Protective Role of Folic Acid in Biochemical and Histopathological Changes Induced by Azithromycin in the Livers of Pregnant Albino Rats by Safaa M. Hanafy, Soha S. Zakaria

    Published 2025-02-01
    “…<i>Background and Objectives</i>: We evaluated the impact of the second-generation macrolide azithromycin on pregnant albino rats’ livers and assessed the protective role of folic acid. <i>Materials and Methods</i>: For this study, forty pregnant rats were treated and then examined. …”
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