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4501
Associations Between Lifetime Histories of Iron Deficiency, Anxiety, Depression and Multiple Pain Conditions: An Observational Study Using a Large-Scale National Database
Published 2025-07-01“…David Champion,1,2 Minh Bui,3 Phillip Aouad,2,* Arthur Teng,1,4,* Arthur S Walters,5,* Elias Georges Karroum,6,* Aidan Christopher Tan,1,2,* Zijing Yang,7,* Emily Joyce,8,* Tiina Jaaniste1,2 1School of Clinical Medicine, University of New South Wales, UNSW, Sydney, NSW, 2052, Australia; 2Department of Pain Medicine, Sydney Children`s Hospital, Randwick, NSW, 2031, Australia; 3Centre for Epidemiology and Biostatistics in the School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia; 4Department of Sleep Medicine, Sydney Children`s Hospital, Randwick, NSW, 2031, Australia; 5Department of Neurology, Sleep Division, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA; 6Department of Neurology, University of Virginia School of Medicine, Charlottesville, VA, 22903, USA; 7Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Rheumatic Diseases, King’s College, London Strand, London, WC2R 2LS, UK; 8Faculty of Science, University of Sydney, Sydney, NSW, 2006, Australia*These authors contributed equally to this workCorrespondence: David Champion, Department of Pain Medicine, Bright Alliance Building, Level 7, Sydney Children`s Hospital, Randwick, NSW, 2031, Australia, Tel +61 410405020, Email gdavidchampion@gmail.comPurpose: Our aims were to investigate in adults, as we have shown in three paediatric samples, associations between a history of iron deficiency (whenever acquired and treated) and history (> 3 months) of primary, overlapping and multisite chronic pain conditions, and to investigate associations between history of iron deficiency, anxiety, and depression.Participants and Methods: We recruited adult twins and their families from the Australian Twin Registry database. …”
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4502
Determining the probability of spondyloarthritis in patients with uveitis
Published 2024-11-01“…SpA was diagnosed in 51/160 pts with unilateral uveitis and was not diagnosed in 109/160 (OR=2.028; 95% CI: 0.913–4.501; p=0.082); out of 48 pts with bilateral uveitis was 9 with SpA and 39 without SpA (OR=0.493; 95% CI: 0.222–1.095; p=0.082); among 149 pts with isolated AU – 55 with SpA and 94 without SpA (OR=6.319; 95% CI: 2.384–16.749; p=0.001); of 59 pts with panuveitis – 5 with SpA and 54 without SpA (OR=0.158; 95% CI: 0.060–0.419; p=0.001); among 159 HLA-B27-positive – 56 with SpA and 103 without SpA (OR=6.117; 95% CI: 2.091–17.888; p=0.001); the onset of uveitis at the age of ≤30 years was in 44/107 pts with SpA and in 63/107 – without SpA (OR=3.710; 95% CI: 1.921–7.168; p=0.001); SpA was confirmed in 39/79 male pts and was not confirmed in 40 (OR=5.014; 95% CI: 2.637–9.535; p=0.001).A formula to determine the probability of SpA in pts with uveitis was obtained by the method of multifactorial discriminant analysis: 1.972 × Х1 + 1.476 × Х2 + 1.418 × Х3 + 1.270 × Х4 + 0.668 × Х5 + 0.162 × Х6, where X1 – male; X2 – the onset of uveitis at the age of ≤30 years; X3 – HLA-B27; X4 – isolated anterior uveitis; X5 – unilateral uveitis; X6 – acute recurrent uveitis.If the amount is greater than 4.552, the probability of SpA is estimated as high, if the amount is less than or equal to 4.552, it is low.Conclusion. …”
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4503
Pemantapan Proses Sintesis Ligan Dibutilditiokarbamat (DBDTK) Sebagai Pengekstrak Logam Tanah Jarang Berdasarkan Desain Eksperimen
Published 2018-09-01“…The prediction of ligand based on the experimental design is 56.12% while the prediction of Gd(III) extraction with ligand of the synthesis result is obtained equal to 78.41%. The conclusion of this research is that the synthesis of dibuthyldithiocarbamate ligand based on the experimental design can be developed for large-scale synthesis.…”
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4504
The effects of esketamine on postoperative delirium in older patients with fragile brain function during the non-acute phase following lung cancer surgery: a randomized controlled...
Published 2025-08-01“…The Confusion Assessment Method (CAM) was used to evaluate the incidence(%) of POD at 24 h and 72 h post-surgery. …”
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4505
Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease
Published 2025-02-01“…The CIBERSORT algorithm and Wilcoxon test method were used to analyze the differences in immune cells between the CAD and normal samples. …”
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4506
Effects of Xenon on Neuroinflammatory Markers: a Prospective Pilot Study
Published 2023-07-01“…Patients were randomized into 2 equal groups. In Group I (Comparison, n=15) in addition to the standard treatment for TBI, each patient included in the study underwent 7 sessions of inhalation of an air mixture with an oxygen content of at least 30 vol.% for 30 minutes. …”
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4507
Efficacy and Safety of Transarterial Chemoembolization Combined with Hepatic Arterial Infusion Chemotherapy Plus Lenvatinib for Intermediate-Stage Hepatocellular Carcinoma Beyond U...
Published 2025-03-01“…Propensity score matching (PSM) and inverse probability weighting (IPTW) were applied to balance baseline differences. The Kaplan–Meier method was utilized for survival analysis. Cox regression-based multivariate analysis was used to identify survival-related risk factors. …”
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4508
Transcription analysis of TIMP-1 and NM23-h1 genes in glioma cell invasion Análise transcricional dos genes TIMP-1 e NM23-H1 na invasão celular em astrocitoma difuso e glioblastoma...
Published 2006-09-01“…PURPOSE: To evaluate using transcription analysis the presence and importance of two genes: NM23-H1 and TIMP-1 on control of tumor cell invasion in diffuse astrocytomas (WHO II) and glioblastoma multiforme (WHO IV). METHOD: Northern blot analysis of NM23-H1 and TIMP-1 was performed. …”
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4509
Diagnostic and Predictive Values of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis: A Multi-Center Prospective Clinical Study
Published 2025-06-01“…Kaifei Wang,1,* Youchen Zhang,2,* Lei Sang,3,* Ye Hu,1,* Longxiang Su,4 Sheling Xie,1 Kun Xiao,1 Jianqiao Xu,1 Jiang Wang,1 Fei Xie,1 Guangfa Zhu,5 Shihui Fu,6– 8 Lixin Xie1 1College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Department of Pediatrics, Hainan Hospital of Chinese PLA General Hospital, Sanya, People’s Republic of China; 3Information Department, Hainan Hospital of Chinese PLA General Hospital, Sanya, People’s Republic of China; 4Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 5Department of Pulmonary and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People’s Republic of China; 6Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Hainan Geriatric Disease Clinical Medical Research Center, Hainan Branch of China Geriatric Disease Clinical Research Center, Sanya, People’s Republic of China; 7Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People’s Republic of China; 8The Second School of Clinical Medicine, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shihui Fu, Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Hainan Geriatric Disease Clinical Medical Research Center, Hainan Branch of China Geriatric Disease Clinical Research Center, Sanya, People’s Republic of China, Email xiaoxiao0915@126.com Lixin Xie, College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, People’s Republic of China, Email xielx301@126.comObjective: To determine diagnostic values of serum and urine soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in sepsis including septic shock and their predictive values for clinical prognosis and sepsis-associated acute kidney injury (AKI).Methods: A multi-center prospective research method was used to enroll patients with sepsis.Results: A total of 586 cases were studied, including 238 patients with sepsis and 348 healthy individuals. …”
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4510
Survival of retinoblastoma patients: a cohort study by two Russian medical centers
Published 2021-03-01“…To evaluate the overall, disease-specific, event-free, relapse-free survival of retinoblastoma (RB) patients and cumulative probability of eye survival in such patients.Material and methods. The study included 223 children with RB (126 male, 97 female). …”
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4511
Electroacupuncture Prevent and Treat Perioperative Cognitive Impairment in Elderly Patients Undergoing Hip Surgery: A Protocol for a Randomized Controlled Trial
Published 2025-06-01“…However, the mechanism of electroacupuncture treatment for PND is comparatively unexplored.Methods/Design: This is a single-center clinical, prospective randomized controlled clinical trial protocol. 180 patients will be randomly divided into the treatment group and the control group in a ratio of 1:1. …”
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4512
Impact of Pre-Interventional Observational Management Duration on Outcomes of Embolization for Splenic Injuries: Experience from Two Centers
Published 2025-08-01“…Van Thang Nguyen,1,2,* Thanh Dung Le,3,4,* Hong Duc Pham,1,5,* Quang Loc Tran3,4,* 1Radiology Department, Hanoi Medical University, Hanoi, Vietnam; 2Radiology Department, Hai Duong Medical Technical University, Hai Duong, Vietnam; 3Radiology Department, VNU University of Medicine and Pharmacy, Hanoi, Vietnam; 4Radiology Department, Viet Duc University Hospital, Hanoi, Vietnam; 5Radiology Department, Saint Paul Hospital, Hanoi, Vietnam*These authors contributed equally to this workCorrespondence: Van Thang Nguyen, Department of Radiology, Hai Duong Medical Technical University, Hai Duong, Vietnam, Email nguyenvanthang@hmtu.edu.vnObjective: To evaluate the clinical and technical success of splenic artery embolization (SAE) in the management of splenic trauma and factors affecting treatment outcomes.Materials and Methods: A retrospective and prospective study was conducted at two centers from December 2019 to December 2023, including 400 patients with splenic trauma (grade III–V according to the American Association for the Surgery of Trauma (AAST) - 2018 classification) and the Abbreviated Injury Scale (AIS) 2005 change from the AIS-1998. …”
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4513
PHASE 2 MULTICENTER RANDOMIZED CLINICAL TRIAL: NEOADJUVANT CHEMORADIOTHERAPY FOLLOWED BY D2 GASTRECTOMY AND ADJUVANT CHEMOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED GASTRIC CANCER
Published 2020-03-01“…Additional objectives of the study were to assess the accuracy of preoperative staging of gastric cancer; tumor regression grade of the primary tumor and regional lymph node metastases according to CT findings; treatment outcomes according to the criteria of frequency and time to recurrence/metastasis; 1-, 2 -, and 3-year survival rates. Material and methods. The study included 70 patients with equal distribution between the treatment groups. …”
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4514
AuNRs-PPARγmAb Induce Targeted Adipocyte Apoptosis Through Photothermal Effects for Effective Localized Fat Reduction
Published 2025-08-01“…This targeted approach offers a promising method for non-surgical, localized fat reduction. …”
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4515
Influence of Noninvasive Respiratory Support Techniques on Gas Exchange in Cardiac Surgical Patients Suffering from Post-Operative Respiratory Failure
Published 2019-09-01“…Every patient was subjected consecutively to arterial blood gases test during room air breathing, low-flow oxygen therapy using a mask with a pre-volume bag, high-flow ventilation (HFNC), and noninvasive positive pressure mask ventilation (NIPPV). Each method was applied during 1 hour prior to the test. …”
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4516
Awake Flexible Bronchoscopy Intubation Practice Among Otorhinolaryngology Surgery: An Observation Study Based on Practice Video Recordings and Clinical Data
Published 2025-08-01“…Baseline characteristics, oxygenation methods, topicalisation, sedation levels, and procedural outcomes were documented. …”
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4517
Small-sided games for technical and tactical development in young rink hockey players (Juegos reducidos para el desarrollo técnico de jóvenes jugadores de hockey sobre patines)
Published 2022-01-01“…For data collection instrument we used the deferred observation method where we proceeded to a descriptive analysis of the data to find the means, standard deviation and totals of: Shots, Passes, Interceptions and Goals. …”
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4518
PLATINUM-BASED CHEMORADIOTHERAPY AS DEFINITIVE TREATMENT IN ADVANCED SQUAMOUS CELL CARCINOMA OF HEAD AND NECK IN REAL-WORLD SETTING
Published 2025-05-01“…Survival outcomes were estimated with the Kaplan-Meier method, and statistical comparisons were performed using the log-rank test and Cox proportional hazards regression for univariate and multivariate analyses. …”
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4519
Enhanced Efficacy of Some Antibiotics in the Presence of Silver Nanoparticles Against Clinical Isolate of Pseudomonas aeruginosa Recovered from Cystic Fibrosis Patients
Published 2024-11-01“…The fractional inhibitory concentration index (FICI) was determined via the checkerboard method to evaluate the synergistic effects of Ag-NPs and various antibiotics.Results: The biosynthesized Ag-NPs were uniformly spherical and measured around 15 nm in size. …”
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4520
The state of the biogeometric profile of the posture of young athletes specializing in hand-to-hand combat as a prerequisite for the development of corrective and preventive measur...
Published 2024-07-01“…The problems identified during the study were solved using generally accepted methods: theoretical analysis of scientific literature on the chosen research topic; the Torso program was used to determine the types of posture, visual screening of the state of the biogeometric profile of the posture of young athletes specializing in hand-to-hand combat included a focus on the tribal system and the use of a method for comparing individual posture on a photogram and methods of mathematical statistics. …”
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