Fracture activation in the overburden and aquiclude stability under the mining of close-distance coal seams by Jian CAO, Haitao SU, Chao WANG, Jianwei LI, Liang LI, Xuwei MAO

“…This is prone to cause aquiclude instability, leading to groundwater loss. MethodsThis study aims to reveal the characteristics of fractures in the overburden and the aquiclude stability in the mining of close-distance coal seams. …”
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Characterization of a Highly Virulent Klebsiella michiganensis Strain Isolated from a Preterm Infant with Sepsis by Xu P, Zhang D, Zhuo W, Zhou L, Du Y, Zhang P, Ma L, Wang Y

“…In future, it will be necessary to investigate the concept of the high virulence of K. michiganensis to determine the treatment method.Keywords: Klebsiella michiganensis, whole-genome sequencing, preterm infant, sepsis…”
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Association Between Sarcopenia Susceptibility and Cesarean Section: A Study Based on National Health and Nutrition Examination Survey (NHANES) and Mendelian Randomization by Tian F, Pan H, Wu Q, Jiang D

“…Feng Tian,1,2,* Huiying Pan,3,4,* Qi Wu,2 Dapeng Jiang2 1Department of Pediatric Surgery, Suzhou Wujiang District Children’s Hospital, Suzhou, Jiangsu Province, People’s Republic of China; 2Department of Oncology (Ward 2), Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 3Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4Department of Obstetrics and Gynecology, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dapeng Jiang, Department of Oncology (Ward 2), Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China, Email jdp509@163.comObjective: To investigate the relationship between sarcopenia susceptibility and cesarean section (CS) and to assess causality using Mendelian randomization (MR).Methods: Data from 1,316 individuals aged from 20– 59 in National Health and Nutrition Examination Survey (NHANES) 2013– 2016 were included in the study. …”
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A New Heterozygous Variant of c.1225_1227delTTC (p.Phe409del) in Insulin Receptor Gene Associated with Severe Insulin Resistance and Hyperandrogenemia in an Adolescent Female with... by Song Y, Lei W, Huang Q, Zhang J, Zhang Q, Chen L, Li H, Liu L, Zeng T, Hu X

“…Yuqing Song,1,2,* Wenjie Lei,1– 3,* Qianqian Huang,1,2 Jiehan Zhang,1,2 Qiao Zhang,4 Lulu Chen,1,2 Huiqing Li,1,2 Li Liu,5 Tianshu Zeng,1,2 Xiang Hu1,2 1Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Provincial Clinical Research Center for Diabetes and Metabolic Disorders, Wuhan, 430022, People’s Republic of China; 3People’s Hospital of Luotian County, Huanggang, 438600, People’s Republic of China; 4Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 5The People’s Hospital of Maojian, Shiyan, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianshu Zeng; Xiang Hu, Email tszeng@126.com; huxiang628@126.comBackground: Functional defects caused by mutations in the insulin receptor (INSR) gene often lead to severe hereditary insulin resistance syndromes, including but not limited to type A insulin resistance syndrome.Method and Result: Here, we report a case of a 12-year-old girl with elevated fasting blood glucose detected by opportunistic testing, associated with severe insulin resistance and hyperandrogenemia. …”
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Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis. by Elizabeth Stratton, Amit Lampit, Isabella Choi, Rafael A Calvo, Samuel B Harvey, Nicholas Glozier

“…<h4>Background</h4>Many organisations promote eHealth applications as a feasible, low-cost method of addressing mental ill-health and stress amongst their employees. …”
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Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach: features of pathomorphological diagnostics by V. A. Tumanskiy, V A. Shavrin

“…It was described the molecular and genetic disorders, as well as the stages of stomach MALT-lymphoma to select the method of patient’s treatment.…”
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The maintenance of competence of rural district hospital medical practitioners by M.R. de Villiers, P.J.T. de Villiers, A. Kent

“…These are not, however, the most appropriate or effective methods of acquiring the knowledge and skills that doctors define as being useful to them. …”
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Trends for Admission, Mortality and Emergency Surgery in Upper Gastrointestinal Bleeding: A Study of Eight Years of Admissions in a Tertiary Care Hospital by Cazacu SM, Parscoveanu M, Rogoveanu I, Goganau A, Vieru A, Moraru E, Cartu D

“…Data regarding mortality were controversial; in non-variceal bleeding, the increasing age of the population, increased use of anti-thrombotic and anticoagulant therapy in patients with cardiovascular diseases, and the use of non-steroidal anti-inflammatory drugs are counterbalanced by the progress in endoscopic therapy with stable mortality.Material and Method: We performed a retrospective, cross-sectional study that included patients admitted with UGIB in Clinical Emergency Hospital Craiova during 2013– 2020.Results: 3571 patients with UGIB were selected; a trend toward increased admission for UGIB from 2013 to 2019 was noted, with a significant decrease in 2020. …”
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A Retrospective Study on the Effect of STA Anesthesia Technique in the Extraction of Impacted Teeth in Dental Outpatients and Its Impact on Patient Anxiety Levels by Xu J, Su J, Liu G, Ying W, Yuan F

“…Jie Xu,1,&amp;ast; Junsen Su,1,&amp;ast; Guangfeng Liu,2 Wanggui Ying,3 Fang Yuan4 1Department of Stomatology, High-Tech District, Jinan Stomatological Hospital, Jinan, People’s Republic of China; 2Department of Stomatology, Wendeng Hospital of Traditional Chinese Orthopedics and Traumatology of Shandong Province, Weihai, Shandong, People’s Republic of China; 3Department of Stomatology, Shungeng District, Jinan Stomatological Hospital, Jinan, People’s Republic of China; 4Department of Prosthodontics, Jinan Stomatological Hospital, Jinan, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Wanggui Ying, Email ywy117@126.com Fang Yuan, Email ynfm053@163.comObjective: To analyze the effect of the Single Tooth Anesthesia (STA) technique in dental outpatient patients undergoing the extraction of impacted teeth and its impact on patient anxiety levels.Methods: This retrospective study included clinical data from 130 patients who underwent the extraction of a single mandibular impacted tooth in our dental outpatient department between April 2022 and June 2024. …”
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The Evaluation of Reference Values of Plasma and Effect-Site Concentrations of Propofol and Remifentanil During Extubation in Patients Who Had Hysteroscopy Procedures by Wei Y, Wang J, Xu Z, Ma R

“…Yu Wei,1– 3,&ast; Jianwei Wang,1– 3,&ast; Zifeng Xu,1– 3 Rui Ma1– 3 1Department of Anesthesiology, the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, Peoples Republic of China; 3Shanghai Municipal Key Clinical Specialty, Shanghai, Peoples Republic of China&ast;These authors contributed equally to this workCorrespondence: Rui Ma; Zifeng Xu, Department of Anesthesiology, the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai Municipal Key Clinical Specialty, Huashan Road 1961, Shanghai, 200030, People’s Republic of China, Tel +86-021-64070434, Email marui_merrygood@163.com; xuzf@shsmu.edu.cnAim: This study aimed to assess the correlation of plasma concentration (Cp) and effect-site concentration (Ce) of propofol and remifentanil with level of consciousness and evaluate their reference values during extubation in patients scheduled day-case operative hysteroscopy under propofol-remifentanil anesthesia.Methods: Propofol (Marsh model) and remifentanil (Minto model) were simultaneously administered using a target-controlled infusion (TCI) pump for the induction and maintenance of anesthesia. …”
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Improving retention of pediatric feeding tubes with a nasal bridle: a randomized controlled trial by Megan Foster, Veronica Armijo-Garcia, Jonathan Gelfond, Andrew D. Meyer

“…Methods A prospective, open-label randomized controlled trial was carried out between February 2020 and January 2021 at a tertiary pediatric hospital. …”
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Characteristics of the blood plasma “lipid peroxidation — antioxidant protection” system depending on nasal mucosa microflora composition in various chronic rhinitis phenotypes... by O. V. Smirnova, N. S. Goncharova

“…At the second stage, the LPO–AOP indices were determined in the blood plasma using a spectrophotometric method. Statistical analysis of the obtained results was performed using the Statistica 8.0 software package. …”
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Caregiver Burden and Its Associated Factors Among Family Caregivers of Hospitalized Patients with Neurocritical Disease: A Cross-Sectional Study by Wei L, Zhao X, Chen X, He Y, Liu J, Xian J, Yang Y

“…Previous studies have focused on caregiver burden for patients in the home rehabilitation stage, while few studies investigate caregiver burden among informal caregivers of early postoperative inpatients.Objective: This study aimed to investigate caregiver burden for caregivers of patients with neurocritical diseases during hospitalization and to identify predictive factors related to caregiver burden.Methods: From November 2023 to April 2024, a cross-sectional study was conducted using a convenience sampling method to assess patients with neurocritical disease and their family caregivers. …”
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Attenuation of acute postoperative pain and opioid requirement with the use of magnesium sulfate in patients undergoing limb amputations by Rabeea Sajid Qureshi, Tanveer Alam, Ahsun Waqar Khan, Muhammad Bilal Shafiq

“…They were randomised into 2 equal groups. The anaesthesia protocol was uniform for all patients. …”
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ILF-neurofeedback in clinical practice: examining symptom change and performance metrics across diagnostic groups by Thomas Theis, Ute Bolduan, Sigrid Seuß, Johannes Spallek, Bernhard Wandernoth, René Mayer-Pelinski, René Mayer-Pelinski

“…IntroductionNeurofeedback (NF), particularly Infra-Low Frequency (ILF) Neurofeedback, is an emerging method of neuromodulation aimed at enhancing the brain’s self-regulation. …”
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Investigating the relationship between personal values and green consumption in students of Shahid Beheshti University by Azadeh Askari, Sepideh Samaee

“…The convenience sampling method was used for sampling. According to the sample size table, 375 people were selected and 353 questionnaires were analyzed. …”
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A Novel Triptolide Nano-Liposome with Mitochondrial Targeting for Treatment of Hepatocellular Carcinoma by Zhou L, Du Y, Shang Y, Xiang D, Xia X

“…In this study, we used triptolide (TP), a bioactive constituent in Tripterygium wilfordii Hook F, as a model drug to develop a novel nano-liposome drug delivery system for the treatment of liver tumours.Methods: We constructed a functionally-modified triptolide liposome (FA+TPP-TP-Lips) using the film-dispersion method and investigated its physicochemical properties, mitochondrial targeting of hepatic tumour cells, in vitro and in vivo anti-hepatic tumour activity and its mechanism.Results: The prepared FA+TPP-TP-Lips had a particle size of 99.28 ± 5.7 nm, a PDI of 0.20 ± 0.02, a zeta potential of 1.2 ± 0.08 mV, and an encapsulation rate of 74.37% ± 1.07%.FA+TPP-TP-Lips facilitates the cellular uptake of drug delivery systems and improves their targeted delivery to mitochondria. …”
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Prevalencia de las limitaciones funcionales durante el envejecimiento en la población española y su relación con el índice de masa corporal (Prevalence of functional limitations d... by Raquel Leirós-Rodríguez, Vicente Romo-Pérez, Anxela Soto-Rodríguez, José L García-Soidán

“…Objective: to describe the prevalence of functional limitations and examine its association with BMI, age, and sex. Method: in this cross-sectional study, data from 5,970 people aged 65 and over (age range 65-94 years) was retrieved from the European Health Survey 2014 (EES14) conducted by the National Statistics Institute and the Ministry of Health, Services Social and Equality of the Spanish Government. …”
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Platelet distribution width as a cost-effective marker for sepsis-associated acute kidney injury: A retrospective cross-section study. by Xuelian Yin, Jiebin Li, Enfeng Ren, Yi Zheng, Hong Zhao, Jing Zhang, Qingxia Du

“…<h4>Objective</h4>This study aims to determine whether platelet distribution width within 24 hours of admission could serve as a predictor of S-AKI in septic patients.<h4>Method</h4>A retrospective analysis of platelet indices in patients with sepsis at the Affiliated Tongren Hospital of Capital Medical University, a tertiary medical center, was conducted from 2015 to 2022. …”
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The Eagle Eyes: an Intervention Utilizing Visual Thinking Strategies to Enhance the Observation Skills of Medical Students by Najmeh Ghorbani, Maryam Alizadeh, Azadeh Sayarifard, Abdoljavad Khajavi, Philip Yenawine

“…While both interventions were equally effective in the delayed follow-up and real-world settings regarding the total number of observations and words used, the VTS and VTA approach led to a notable increase in the time spent on observation descriptions. …”
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