Is the combination of linagliptin and allopurinol better prophylaxis against post-contrast acute kidney injury? A multicenter prospective randomized controlled study by Ahmed Fayed, Ahmed A. Hammad, Dina O. Abdulazim, Hany Hammad, Mohamed Amin, Samir Elhadidy, Mona M. Salem, Ibrahim M. Abd ElAzim, Lajos Zsom, Eva Csongradi, Karim M. Soliman, Usama A. Sharaf El Din

“…We speculated that linagliptin as a single agent or in combination with allopurinol may reduce the incidence of post-contrast AKI in stage 3–5 chronic kidney disease (CKD) patients with underlying DKD.Methods Out of 951 DKD patients eligible for this study, 800 accepted to sign informed consent. …”
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Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment by Eric A. Smith, Rachel L. Belote, Nelly M. Cruz, Tarek E. Moustafa, Carly A. Becker, Amanda Jiang, Shukran Alizada, Anastasia Prokofyeva, Tsz Yin Chan, Tori A. Seasor, Michael Balatico, Emilio Cortes-Sanchez, David H. Lum, John R. Hyngstrom, Hanlin Zeng, Dekker C. Deacon, Allie H. Grossmann, Richard M. White, Thomas A. Zangle, Robert L. Judson-Torres

“…Methods An independent analysis of published sequencing data was performed to evaluate the frequency of receptor tyrosine kinase (RTK) ligands and adapter protein gene variants and expression. …”
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An Italian Survey on the Management of Pediatric Convulsive Status Epilepticus: More Than Just a Pharmacological Choice by Caterina Zanus, Giulia Cannizzaro, Giacomo Danieli, Angela Amigoni, Silvia Buratti, Francesca Izzo, Massimo Mastrangelo, Maria Cristina Mondardini, Paola Costa, Anna Rosati, Carla Marini, Lucia Fusco, Italian Paediatric Status Epilepticus Group

“…Abstract Background and Purpose To explore specialists’ opinions on the current management of pediatric convulsive status epilepticus (CSE) in Italy and the main factors influencing the applicability of guidelines. Methods We conducted a national survey of child neurologists, pediatric emergency physicians, and intensivists. …”
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Acromegaly as a Multisystem Disease – Analysis of Metabolic Complications. Review of Current Literature by Daria Anna Krzyżanowska, Paula Bętkowska, Magdalena Strzelczyk, Joanna Wziątek, Iwona Koziołek, Gabriela Pabis, Patrycja Fatyga, Wiktoria Fatyga, Piotr Kowalik, Kinga Dowierciał

“…The aim of this review is to deepen the understanding of acromegaly as a systemic disease, with particular emphasis on its metabolic complications.  Material and methods The paper analyzes scientific publications on acromegaly and its metabolic complications published between 2008 and 2024. …”
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Influence of Emergent Vegetation Layout on Flow Pattern in a Rectangular Shallow Basin by Junnan LYU, Yuxuan JIANG, Zhidong YAO, Chen YE, Xufeng YAN

“…Prior research has extensively debated shallow basins’ functions and influencing factors from these perspectives, employing methods such as field investigations, aerial remote sensing, physical experiments, large-scale modeling, and surveys. …”
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Medical-psychological aspects of professional deformation of personality development among emergency medical staff by O. S. Lalymenko, І. V. Zavhorodnii, V. A. Kapustnyk, I. Boeckelmann, V. F. Zabashta, M. O. Stytsenko

“…To study the specifics of professional burnout formation considering the relationship between its levels and typological personality traits of emergency medical staff. Materials and methods. A medical and psychological survey was conducted among 120 medical professionals of the “Regional Clinical Hospital – Center for Emergency Medical Care and Disaster Medicine” in Kharkiv, Ukraine. …”
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A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development by Cristóbal Vacarezza, Julieta Araneda, Pamela Gonzalez, Oscar Arteaga, Katherine Marcelain, Enrique A. Castellon, Ana Periera, Maroun Khoury, Bettina Müller, Juan Alberto Lecaros, Sofia P. Salas, Arnoldo Riquelme, Alejandro H. Corvalan, Jorge Jiménez de la Jara, Catterina Ferreccio, Carolina Goic, Bruno Nervi, Juan Carlos Roa, Gareth I. Owen

“…Present actions for the development of oncology research, innovation and patient care. Methods Triangulating objective system metrics of economic, epidemiological, private and public sector resources together with policy analysis, we assessed cancer burden, infrastructure, and investigation. …”
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Performance of Current Chronic Kidney Disease Screening Criteria in Women and Men Across Ethnic Groups: The HELIUS Study by Taryn G. Vosters, MSc, Vianda S. Stel, PhD, Kitty J. Jager, MD, PhD, Bart Ferwerda, PhD, Roos F. Marsman, MD, PhD, Frans J. van Ittersum, MD, PhD, Bert-Jan H. van den Born, MD, PhD, Henrike Galenkamp, PhD, Liffert Vogt, MD, PhD, Irene G.M. van Valkengoed, PhD

“…Patients and Methods: We included 12,384 women and 9046 men of Dutch, South Asian and African Surinamese, Ghanaian, Turkish, and Moroccan origin from the baseline HELIUS Study (January 1, 2011, through December 31, 2015, Amsterdam, the Netherlands). …”
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Sleep quality, daytime sleepiness, and obstructive sleep apnea risk among iranian commercial airline pilots by Asghar Akhavan, Mahdieh Hasanalifard, Reyhaneh Abolghasemi, Abolfazl Khamaki, Shokofeh Radfar, Taleb Badri

“…In this matched cross-sectional comparative study, the sleep status and related factors in commercial airline flight pilots were evaluated. Methods: All pilots and the healthy sex- and age-matched controls who met the inclusion criteria and signed informed consent were included in the study. …”
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Forensic psychiatric care professionals’ experiences of communicating with foreign patients and their relatives: the importance of language and culture by Omed Abdul Rahman, Omed Abdul Rahman, Omed Abdul Rahman, Eirini Alexiou, Eirini Alexiou, Alessio Degl’Innocenti, Alessio Degl’Innocenti, Christopher Holmberg, Christopher Holmberg, Christopher Holmberg, Patricia Olaya-Contreras, Patricia Olaya-Contreras

“…The aim of this study was to explore the experiences of forensic psychiatric professionals and identify factors influencing effective communication in their interactions with patients and their relatives who have limited proficiency in Swedish.MethodsNine professionals specializing in forensic psychiatry— including physicians, registered nurses, and counselors—participated in deep individual interviews. …”
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Standardizing smokeless tobacco packs in India to enhance health warning visibility and harm perceptions by Hannah E. Barker, Raniyan Zaman, Lauren Czaplicki, Sejal Saraf, Rana J. Singh, Ashish K. Pandey, Joanna E. Cohen

“…This study explored consumer perceptions of existing khaini packs and two proposed standard shape/size khaini packs across dimensions of HWL noticeability and harm perceptions. Methods In March 2023, we conducted 24 focus groups (FGs) across India. …”
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Risk factors affecting long-term efficacy of ultrasound-guided high-intensity focused ultrasound treatment for multiple uterine fibroids by Zhenjiang Lin, Feng Xu, Yuan Yuan, Jiaojiao Peng, Jin Luo, Chunmei Gong, Dayong Chen, Yangyang Wang, Donghong Wang, Bing Yang, Lian Zhang

“…Objectives To investigate the long-term efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) for multiple uterine fibroids and the factors associated with recurrence.Materials and methods Five hundred and forty-nine patients with multiple uterine fibroids treated with USgHIFU from June 2017 to June 2019 were retrospectively analyzed. …”
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Comparative analysis of autodermal graft and polypropylene mesh use in large incisional hernia defects reconstruction by Stojiljković Danilo, Kovačević Predrag, Višnjić Milan, Janković Irena, Stevanović Goran, Stojiljković Predrag, Stojiljković Marija, Trenkić Milan, Golubović Zoran, Ignjatović Nebojša, Dimitrijević Zorica, Kovačević Tatjana, Stošić Biljana, Bagur Nataša

“…The aim of the study was to comparatively analyse efficacy and safety of autodermal graft and polypropylene mesh in surgical treatment of large abdominal wall defects. Methods. This prospective comparative clinical study enroled 40 patients surgically treated for large incisional hernia repair in a 10-year period. …”
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Real world treatment patterns for recurrent and metastatic head and neck cancer in the post-KEYNOTE 048 era by Daniel Y. Lee, Alexander Pan, Maxim Yaskolko, Michael Chiorazzi, Aarti Bhatia, Barbara Burtness, Jeffrey J. Ishizuka, Jeffrey J. Ishizuka, Jeffrey J. Ishizuka

“…BackgroundWhile KEYNOTE-048 established anti-PD1 with or without chemotherapy as first-line treatment for recurrent and metastatic head and neck squamous cell carcinoma (HNSCC) with combined positive score (CPS) ≥ 1, treatment choice remains ambiguous given additional toxicity of combination treatment.MethodsPatients treated first-line with anti-PD1 monotherapy, anti-PD1+chemotherapy, or cetuximab+chemotherapy in the Flatiron Health database were included. …”
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Causes and MEchanisms foR non-atopic Asthma in Children (CAMERA) study: rationale and protocol by Mary Njoroge, Gabriela Pimentel Pinheiro, Cinthia Vila Nova Santana, Hajar Ali, Stephanie Hobbs, Santiago Mena-Bucheli, Natalia Romero-Sandoval, Steven Robertson, Charlotte E. Rutter, Donna Davoren, Collin Brooks, Jeroen Douwes, Philip J. Cooper, Harriet Mpairwe, Camila A. Figueiredo, Alvaro A. Cruz, Mauricio L. Barreto, Neil Pearce, Lucy Pembrey, the CAMERA study group

“…The focus of this paper is the protocol for sample collection and analysis of clinical data on possible non-atopic mechanisms. Methods In each of the four centres, the CAMERA study will enroll 160 participants aged 10–28 years, equally distributed among atopic asthmatics (AA), non-atopic asthmatics (NAA), atopic non-asthmatics and non-atopic non-asthmatics. …”
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The necessity of thyroid-stimulating hormone suppression therapy for low-risk differentiated thyroid carcinoma following hemithyroidectomy: A systematic review and meta-analysis by Xinyu Wang, Yuqian Ye, Mizaniya Amdulla, Chenglong Ren, Yunhe Liu, Song Ni

“…This study aims to conduct a comprehensive literature review concerning the necessity of TSH suppression therapy in DTC after hemithyroidectomy. Methods: A systematic search of publicly available literature on postoperative TSH suppression therapy in DTC was conducted by querying databases such as PubMed, Embase, Cochrane, and Web of Science. …”
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Transurethral prostate surgery in prostate cancer patients: A population-based comparative analysis of complication and mortality rates by Michele Marchioni, Giulia Primiceri, Alessandro Veccia, Marta Di Nicola, Umberto Carbonara, Fabio Crocerossa, Ugo Falagario, Ambra Rizzoli, Riccardo Autorino, Luigi Schips

“…We aimed to test the effect of PCa versus BPH on surgical outcomes after transurethral prostate surgery, namely complication and mortality rates. Methods: Within the American College of Surgeons National Surgical Quality Improvement Program database (2011–2016), we identified patients who underwent transurethral resection of the prostate, photoselective vaporization, or laser enucleation. …”
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Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes by Michelle Horan, Michelle Horan, Daniel Carey, Daniel Carey, Silvin Knight, Silvin Knight, A. Fagan, James F. M. Meaney, James F. M. Meaney, Rose Anne Kenny, Rose Anne Kenny, Rose Anne Kenny, Céline De Looze, Céline De Looze

“…In this study, we investigate the independent and moderating effects of increased arterial stiffness (AS) and reduced cerebral blood flow (CBF) on hippocampal volume (HV) in a large MRI sample of community-dwelling older adults from the Irish Longitudinal Study on Ageing (TILDA).MethodsLongitudinal data from study participants for Wave 1 (2009–2011) and Wave 3 (2014-2015) were included. …”
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Prevalence of airway hyperresponsiveness and its seasonal variation in children with asthma by Shu-Jung Huang, Li-Lun Lin, Li-Chen Chen, Liang-Shiou Ou, Tsung-Chieh Yao, Kuo-Chien Tsao, Kuo-Wei Yeh, Jing-Long Huang

“…However, these studies have mostly been conducted in temperate regions.This study evaluated the prevalence of AHR to methacholine and its seasonal variation in asthmatic children in Taiwan, a subtropical country. Methods: A total of 276 children with asthma and their MCCT results were retrospectively reviewed. …”
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Proteomics analysis reveals the mechanism of anemoside B4 in treating clinical mastitis in dairy cows by Zeru Zhang, Yuquan Zhao, Zhetong Su, Ke Dong, Zhicai Zuo, Yixin Huang, Shumin Yu, Suizhong Cao, Liuhong Shen

“…This study was based on Label free relative quantitative proteomics technology to reveal the internal mechanism of AB4 treatment of CM; (2) Methods: Twelve healthy Chinese Holstein cows (group C) and twelve Chinese Holstein cows (group T) with CM were selected. …”
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